stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Feix JB et al. | An electron-electron double-resonance study of interactions between [14N]- and [15N]stearic acid spin-label pairs: lateral diffusion and vertical fluctuations in dimyristoylphosphatidylcholine. | 1984 | Biochemistry | pmid:6329270 |
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Lem NW and Stumpf PK | In Vitro Fatty Acid Synthesis and Complex Lipid Metabolism in the Cyanobacterium, Anabaena Variabilis: II. Acyl Transfer and Complex Lipid Formation. | 1984 | Plant Physiol. | pmid:16663690 |
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Bhakoo KK et al. | Regional studies of changes in brain fatty acids following experimental ischaemia and reperfusion in the gerbil. | 1984 | J. Neurochem. | pmid:6236282 |
Abumrad NA et al. | Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. | 1984 | J. Biol. Chem. | pmid:6746632 |
Zoeller RA and Wood R | Effects of cyclopropene fatty acids on the lipid composition of the Morris hepatoma 7288C. | 1984 | Lipids | pmid:6431218 |
Sivarajan M et al. | Regulation of intracellular arachidonate in normal and stressed endothelial cells. | 1984 | Biochim. Biophys. Acta | pmid:6433983 |
Rosén C et al. | Acute otitis media in older children and adults treated with penicillin or erythromycin. | 1984 | Acta Otolaryngol Suppl | pmid:6437133 |
Dixon JF and Hokin LE | Secretogogue-stimulated phosphatidylinositol breakdown in the exocrine pancreas liberates arachidonic acid, stearic acid, and glycerol by sequential actions of phospholipase C and diglyceride lipase. | 1984 | J. Biol. Chem. | pmid:6438097 |
Forsberg NE et al. | Roles of acetate and its interactions with glucose and lactate in cow mammary tissue. | 1984 | J. Dairy Sci. | pmid:6438200 |
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Fenyvest E et al. | Cyclodextrin polymer, a new tablet disintegrating agent. | 1984 | Pharmazie | pmid:6494226 |
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Kennett FF et al. | Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds. | 1984 | Am. J. Physiol. | pmid:6507637 |
Wirthensohn G et al. | Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal substrates. | 1984 | Biochim. Biophys. Acta | pmid:6477951 |
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Slevin ML et al. | The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension. | 1984 | Invest New Drugs | pmid:6511233 |
Vandermeerschen-Doizé F and Paquay R | Effects of continuous long-term intravenous infusion of long-chain fatty acids on feeding behaviour and blood components of adult sheep. | 1984 | Appetite | pmid:6517567 |
Hunter JM and Sommerville RG | Erythromycin stearate in treating chlamydial infection of the cervix. | 1984 | Br J Vener Dis | pmid:6518350 |
Farkas T | Adaptation of fatty acid composition to temperature--a study on carp (Cyprinus carpio L.) liver slices. | 1984 | Comp. Biochem. Physiol., B | pmid:6518757 |
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Rosén C et al. | Acute otitis media in older children and adults treated with phenoxymethyl penicillin or erythromycin stearate. Bacteriological and immunological aspects. | 1983 Sep-Oct | Acta Otolaryngol. | pmid:6416018 |
Robson HG et al. | Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. | 1983 Jul-Sep | Sex Transm Dis | pmid:6648747 |
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