stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Conte U et al. | The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. | 1972 | Farmaco Prat | pmid:5049531 |
Lesslauer W and Blasie JK | Direct determination of the structure of barium stearate multilayers by x-ray diffraction. | 1972 | Biophys. J. | pmid:5057749 |
Price CJ and Rowe CE | Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. | 1972 | Biochem. J. | pmid:5075269 |
Patil GS et al. | Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. | 1972 | J. Lipid Res. | pmid:5075503 |
Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. | 1972 | Yakugaku Zasshi | pmid:4675495 |
Zackler J et al. | A mass screening program for the detection of gonorrhea. | 1972 | Am. J. Obstet. Gynecol. | pmid:4623083 |
Wahle KW and Garton GA | Desaturation of stearate by sheep tissue microsomal preparations. | 1972 | Biochem. J. | pmid:4643297 |
Kannangara CG and Stumpf PK | Fat Metabolism in Higher Plants: XLVII. The Effect of Nitrite and Other Anions on the Formation of Unsaturated Fatty Acids by Isolated Chloroplasts. | 1972 | Plant Physiol. | pmid:16657990 |
Miyake Y et al. | [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. | 1973 | Yakugaku Zasshi | pmid:4797567 |
Ryan DC et al. | Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4568626 |
Bond JM et al. | The second international reference preparation of procaine benzylpenicillin in oil with aluminium monostearate. | 1973 | Bull. World Health Organ. | pmid:4541152 |
Arya OP and Bosa CB | In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. | 1973 | Br J Vener Dis | pmid:4748409 |
McLeay A and Cooke P | Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. | 1973 | Med. J. Aust. | pmid:4694278 |
Norwitz G and Gordon H | Determination of lithium stearate in sebacate-based lubricants by atomic absorption. | 1973 | Talanta | pmid:18961363 |
Caldwell HC | Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. | 1974 | J Pharm Sci | pmid:4830001 |
Beleslin DB et al. | Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. | 1974 | Neuropharmacology | pmid:4840846 |
Kasuya M et al. | Toxic effect of cadmium stearate on rat cerebellum in culture. | 1974 | Bull Environ Contam Toxicol | pmid:4474041 |
Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. | 1974 | Practitioner | pmid:4591200 | |
Wood R | Sterospecific analysis of hepatoma, host liver, and normal rat liver triglycerides from animals on chow and fat free diets. | 1975 | Lipids | pmid:167260 |
Iot T et al. | Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes. | 1975 | Biochemistry | pmid:167814 |
Thompson W and MacDonald G | Isolation and characterization of cytidine diphosphate diglyceride from beef liver. | 1975 | J. Biol. Chem. | pmid:169258 |
Morrisett JD et al. | Multiple thermotropic phase transitions in Escherichia coli membranes and membrane lipids. A comparison of results obtained by nitroxyl stearate paramagnetic resonance, pyrene excimer fluorescence, and enzyme activity measurements. | 1975 | J. Biol. Chem. | pmid:169264 |
Asker AF et al. | Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. | 1975 | Pharmazie | pmid:169527 |
McGee R and Spector AA | Fatty acid biosynthesis in Erlich cells. The mechanism of short term control by exogenous free fatty acids. | 1975 | J. Biol. Chem. | pmid:237919 |
Choulis NH and Papadopoulos H | Factors effecting drug release from inert matrices. Part 1: effects of surfactants on the release of quinine sulfate. | 1975 | Pharmazie | pmid:239411 |
Kalm O et al. | Erythromycin stearate in acute maxillary sinusitis. | 1975 | Scand. J. Infect. Dis. | pmid:241119 |
Bieri VG and Wallach DF | Variations of lipid-protein interactions in erythrocyte ghosts as a function of temperature and pH in physiological and non-physiological ranges. A study using a paramagnetic quenching of protein fluorescence by nitroxide lipid analogues. | 1975 | Biochim. Biophys. Acta | pmid:241415 |
Seng PN and Debuch H | [Studies on the stearic acid dehydrogenase in the liver and brain of rats of various ages (author's transl)]. | 1975 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:241688 |
Topping DL and Targ ME | Time-course of changes in blood glucose and ketone bodies, plasma lipids and liver fatty acid composition in streptozotocin-diabetic male rats. | 1975 | Horm. Res. | pmid:130333 |
Comai K et al. | Analyses of renal medullary lipid droplets from normal, hydronephrotic, and indomethacin treated rabbits. | 1975 | Lipids | pmid:1177669 |
Thompson GE and Darling KF | The hepatic uptake of individual free fatty acids in sheep during noradrenaline infusion. | 1975 | Res. Vet. Sci. | pmid:1144925 |
York P | Application of powder failure testing equipment in assessing effect on glidants on flowability of cohesive pharmaceutical powders. | 1975 | J Pharm Sci | pmid:1151687 |
Weaire PJ and Kekwick RG | The fractionation of the fatty acid synthetase activities of avocado mesocarp plastids. | 1975 | Biochem. J. | pmid:1156381 |
Janicki RS et al. | Comparison of erythromycin ethyl succinate, stearate and estolate treatments of group A streptococcal infections of the upper respiratory tract. | 1975 | Clin Pediatr (Phila) | pmid:1104241 |
Männistö P et al. | Absorption of erythromycin. A cross-over study in healthy volunteers. | 1975 | Arzneimittelforschung | pmid:1106445 |
Anderson RR et al. | Composition of cottontail rabbit milk from stomachs of young and directly from gland. | 1975 | J. Dairy Sci. | pmid:1184805 |
Smith RW and Walsh A | Composition of liver lipids of the rat during pregnancy and lactation. | 1975 | Lipids | pmid:1186452 |
Schmidt P et al. | [Animal experiments on barium stearate toxicity]. | 1975 | Z Gesamte Hyg | pmid:1189478 |
Sato M et al. | [Clinical studies on OE-7 chiefly in the treatment of acute respiratory infections (author's transl)]. | 1975 | Jpn J Antibiot | pmid:1195513 |
Harwood JL and James AT | Metabolism of trans-3-hexadecenoic acid in broad bean. | 1975 | Eur. J. Biochem. | pmid:1126340 |
Kuksis A et al. | Distribution of newly formed fatty acids among glycerolipids of isolated perfused rat liver. | 1975 | Can. J. Biochem. | pmid:1139394 |
Kuksis A et al. | Distribution of newly formed palmitate and stearate among molecular species of choline and ethanolamine phosphatides. | 1975 | Can. J. Biochem. | pmid:1139395 |
Parkes JG and Thompson W | Phosphatidylethanolamine in liver mitochondria and endoplasmic reticulum: molecular species distribution and turnover. | 1975 | Can. J. Biochem. | pmid:1139407 |
Tola S | Occupational lead exposure in Finland. IV. The polyvinyl chloride plastic industry. | 1975 | Scand J Work Environ Health | pmid:1228897 |
Kopp F et al. | Instability of Langmuir-Blodgett layers of barium stearate, cadmium arachidate and tripalmitin, studied by means of electron microscopy and infrared spectroscopy. | 1975 | Biophys. Struct. Mech. | pmid:1234025 |
Gray AP and Guardina WJ | Long-acting narcotic antagonist complexes. | 1975 | Natl Inst Drug Abuse Res Monogr Ser | pmid:1234981 |
Ercoli N | [Clinical and experimental study on an anti-inflammatory preparation of topical use. The 10-undecentil-l-ll pseudothiourea (AHR-1911)]. | 1975 | Med Cutan Ibero Lat Am | pmid:1241792 |
Thies C | Development of injectable microcapsules for use in the treatment of narcotic addiction. | 1975 | Natl Inst Drug Abuse Res Monogr Ser | pmid:1241971 |
Aveldano MI and Bazán NG | Rapid production of diacylglycerols enriched in arachidonate and stearate during early brain ischemia. | 1975 | J. Neurochem. | pmid:1206411 |
Pollet S et al. | [Substrates and products of fatty acid elongation in mouse brain microsomes]. | 1975 | Biochimie | pmid:1222143 |