stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
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What lipids are associated with stearic acid?
Related references are published most in these journals:
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen Y et al. | A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. | 2010 | Appl Spectrosc | pmid:20925991 |
| Mukherjee S et al. | Stearic acid delivery to corneum from a mild and moisturizing cleanser. | 2010 | J Cosmet Dermatol | pmid:20883293 |
| Salem HF | Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats. | 2010 | Int J Nanomedicine | pmid:21187946 |
| Fang X et al. | Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. | 2010 | BMC Syst Biol | pmid:21092312 |
| Rideout TC et al. | Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice. | 2010 | Mol Nutr Food Res | pmid:20333723 |
| Daraghmeh N et al. | Preparation and characterization of a novel co-processed excipient of chitin and crystalline mannitol. | 2010 | AAPS PharmSciTech | pmid:21052880 |
| Rawat MK et al. | Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. | 2010 | Ther Deliv | pmid:22816120 |
| Zornetzer GA et al. | The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond. | 2010 | Biochemistry | pmid:20014832 |
| Westerbacka J et al. | Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. | 2010 | Gastroenterology | pmid:20600015 |
| Shen J et al. | Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: Improving in vivo ocular distribution. | 2010 | Int J Pharm | pmid:20934499 |
| Almeida CP et al. | Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. | 2010 | Int J Nanomedicine | pmid:20957219 |
| Ram HN et al. | Formulation and evaluation of floating tablets of liquorice extract. | 2010 | Pharmacognosy Res | pmid:21589757 |
| Varshosaz J et al. | Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. | 2010 | Int J Prev Med | pmid:21566772 |
| Alizadeh M et al. | The effect of hypocaloric diet enriched in legumes with or without L-arginine and selenium on anthropometric measures in central obese women. | 2010 | J Res Med Sci | pmid:21526106 |
| Araújo J et al. | Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. | 2010 | Int J Pharm | pmid:20362042 |
| Bender K et al. | Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. | 2010 | Reproduction | pmid:20385782 |
| Pedersen PJ et al. | Liposomal formulation of retinoids designed for enzyme triggered release. | 2010 | J. Med. Chem. | pmid:20405849 |
| Jain S et al. | Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. | 2010 | J Young Pharm | pmid:21264091 |
| Liew CV et al. | In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. | 2010 | Int J Pharm | pmid:19922776 |
| Naumova EA et al. | Influence of individual saliva secretion on fluoride bioavailability. | 2010 | Open Dent J | pmid:21221176 |
| Harvey KA et al. | Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. | 2010 | Clin Nutr | pmid:19926177 |
| Patel BP et al. | Formulation and evaluation of mouth dissolving tablets of cinnarizine. | 2010 | Indian J Pharm Sci | pmid:21218071 |
| Kotagale NR et al. | Carbopol 934-Sodium Alginate-Gelatin Mucoadhesive Ondansetron Tablets for Buccal Delivery: Effect of pH Modifiers. | 2010 | Indian J Pharm Sci | pmid:21218058 |
| Zhou Q et al. | Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating. | 2010 | J Pharm Sci | pmid:19795479 |
| Swami G et al. | Soyabean powder as a novel diluent in tablet formulation of simvastatin. | 2010 | Indian J Pharm Sci | pmid:21218051 |
| Balch RJ and Trescot A | Extended-release morphine sulfate in treatment of severe acute and chronic pain. | 2010 | J Pain Res | pmid:21197323 |
| Uchimoto T et al. | Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate. | 2010 | Int J Pharm | pmid:19913080 |
| Nouri A et al. | Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. | 2010 | Acta Biomater | pmid:19815096 |
| El Hadrami A et al. | Chitosan in plant protection. | 2010 | Mar Drugs | pmid:20479963 |
| Luan L et al. | [Studies on the chemical constituents of extract with water from Forsythia suspensa]. | 2010 | Zhong Yao Cai | pmid:20575415 |
| Remya K et al. | Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets. | 2010 | J Young Pharm | pmid:21042477 |
| Contreras GA et al. | Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. | 2010 | J. Dairy Sci. | pmid:20494158 |
| Sateesha S et al. | Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. | 2010 | J Young Pharm | pmid:21042476 |
| Karande AD et al. | In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. | 2010 | Int J Pharm | pmid:20558264 |
| Hurko O et al. | Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. | 2010 | Int J Alzheimers Dis | pmid:20981353 |
| Kim IS and Oh IJ | Preparation and characterization of stearic acid-pullulan nanoparticles. | 2010 | Arch. Pharm. Res. | pmid:20512475 |
| A J et al. | Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses. | 2010 | PLoS ONE | pmid:20949032 |
| Wang J et al. | Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. | 2010 | J Pharm Sci | pmid:20533436 |
| Karande AD et al. | Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend. | 2010 | Int J Pharm | pmid:20472048 |
| Thörn K et al. | Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells. | 2010 | Lipids Health Dis | pmid:20920255 |
| Akihisa T et al. | Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. | 2010 | J Oleo Sci | pmid:20513968 |
| Aly S | Detachment and recovery index: A new parameter measuring powder compressibility. | 2010 | J Adv Pharm Technol Res | pmid:22247881 |
| Brown AW et al. | Plant sterol and stanol substrate specificity of pancreatic cholesterol esterase. | 2010 | J. Nutr. Biochem. | pmid:19615880 |
| Tripathi B and Platel K | Finger millet (Eleucine coracana) flour as a vehicle for fortification with zinc. | 2010 | J Trace Elem Med Biol | pmid:20122580 |
| Pires de Souza FC et al. | In vitro comparison of the radiopacity of cavity lining materials with human dental structures. | 2010 | J Conserv Dent | pmid:20859477 |
| Lyra A et al. | Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes. | 2010 | BMC Gastroenterol | pmid:20849659 |
| Huang WH et al. | Development of liposomal salbutamol sulfate dry powder inhaler formulation. | 2010 | Biol. Pharm. Bull. | pmid:20190418 |
| Jeong SH and Park K | Simple preparation of coated resin complexes and their incorporation into fast-disintegrating tablets. | 2010 | Arch. Pharm. Res. | pmid:20191352 |
| Cho KH et al. | Monoacylglycerol (MAG)-oleic acid has stronger antioxidant, anti-atherosclerotic, and protein glycation inhibitory activities than MAG-palmitic acid. | 2010 | J Med Food | pmid:20136442 |
| Yang X et al. | In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. | 2010 | Drug Dev Ind Pharm | pmid:20141448 |
| Du YZ et al. | Stearic acid grafted chitosan oligosaccharide micelle as a promising vector for gene delivery system: factors affecting the complexation. | 2010 | Int J Pharm | pmid:20170716 |
| Baki G et al. | Role of surface free energy and spreading coefficient in the formulation of active agent-layered pellets. | 2010 | Eur J Pharm Biopharm | pmid:19931611 |
| Eftaiha AF et al. | Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. | 2010 | Mar Drugs | pmid:20559494 |
| Normand-Lauzière F et al. | Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. | 2010 | PLoS ONE | pmid:20532041 |
| Do PT et al. | The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. | 2010 | Plant Physiol. | pmid:20841452 |
| Rivera CA et al. | Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. | 2010 | BMC Gastroenterol | pmid:20509914 |
| Barupal DK et al. | Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. | 2010 | BMC Biotechnol. | pmid:20492649 |
| Ye M et al. | Synthesis of Sb2E3 (E = S, Se) nanorods with a flat cross section by a rapid hot injection method. | 2010 | J Nanosci Nanotechnol | pmid:21138031 |
| Xu Y et al. | Carbon-covered magnetic nanomaterials and their application for the thermolysis of cancer cells. | 2010 | Int J Nanomedicine | pmid:20463932 |
| Harvey KA et al. | Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. | 2010 | J. Lipid Res. | pmid:20852092 |
| Prossnigg F et al. | Packing behaviour of two predominant anionic phospholipids of bacterial cytoplasmic membranes. | 2010 | Biophys. Chem. | pmid:20451316 |
| Chitapanarux I et al. | Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. | 2010 | Radiat Oncol | pmid:20444243 |
| Blanco M and Peguero A | Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. | 2010 | J Pharm Biomed Anal | pmid:20044229 |
| Howell AB et al. | Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. | 2010 | BMC Infect. Dis. | pmid:20398248 |
| UÄŸurlu T et al. | Effects of lubricants on binary direct compression mixtures. | 2010 | Drug Discov Ther | pmid:22491169 |
| Saravanakumari P and Mani K | Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. | 2010 | Bioresour. Technol. | pmid:20637606 |
| Invernizzi G et al. | Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements. | 2010 | Funct. Integr. Genomics | pmid:20607344 |
| Chon B et al. | Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals. | 2010 | Phys Chem Chem Phys | pmid:20607188 |
| Lin SY et al. | Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. | 2010 | Int J Pharm | pmid:20561572 |
| Bunn RC et al. | Palmitate and insulin synergistically induce IL-6 expression in human monocytes. | 2010 | Cardiovasc Diabetol | pmid:21054880 |
| Asai T and Fujimoto Y | Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. | 2010 | Phytochemistry | pmid:20541780 |
| Foster SP and Johnson CP | Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. | 2010 | J. Insect Physiol. | pmid:20540946 |
| Thörn K and Bergsten P | Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. | 2010 | J. Cell. Biochem. | pmid:20524206 |
| Zhou QT et al. | Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders. | 2010 | Eur J Pharm Sci | pmid:20433919 |
| Nokhodchi A et al. | Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives. | 2010 | Daru | pmid:22615598 |
| Croxton RS et al. | Variation in amino acid and lipid composition of latent fingerprints. | 2010 | Forensic Sci. Int. | pmid:20413233 |
| Milanovic J et al. | Microencapsulation of flavors in carnauba wax. | 2010 | Sensors (Basel) | pmid:22315575 |
| Shi X et al. | On the coating of precipitated calcium carbonate with stearic acid in aqueous medium. | 2010 | Langmuir | pmid:20334413 |
| Nagaich U et al. | Design and evaluation of a metronidazole central core matrix tablet. | 2010 | J Adv Pharm Technol Res | pmid:22247836 |
| Hsieh HT et al. | Facile synthesis of silver nanoparticles in CO2-expanded liquids from silver isostearate precursor. | 2010 | Langmuir | pmid:20297774 |
| Bhattacharya S and Nagaich U | Assessment of anti-nociceptive efficacy of costus speciosus rhizome in swiss albino mice. | 2010 | J Adv Pharm Technol Res | pmid:22247830 |
| Xing Z et al. | Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. | 2010 | Acta Biomater | pmid:20226284 |
| Choi JN et al. | Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. | 2010 | J. Agric. Food Chem. | pmid:20225861 |
| O'Byrne SM et al. | Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20040693 |
| Desando MA et al. | Proton magnetic relaxation and the aggregation of n-octylammonium n-octadecanoate surfactant in deuterochloroform solution. | 2010 | J Colloid Interface Sci | pmid:20223468 |
| Collins JM et al. | De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. | 2010 | J. Biol. Chem. | pmid:20032470 |
| Salbu L et al. | Direct compression behavior of low- and high-methoxylated pectins. | 2010 | AAPS PharmSciTech | pmid:20013080 |
| Kordyukova LV et al. | Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. | 2010 | Virology | pmid:20006369 |
| Kushner J and Moore F | Scale-up model describing the impact of lubrication on tablet tensile strength. | 2010 | Int J Pharm | pmid:20667504 |
| Imae R et al. | Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. | 2010 | Mol. Biol. Cell | pmid:20668164 |
| Su C et al. | A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. | 2010 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:20732836 |
| Yoo HJ and HÃ¥kansson K | Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. | 2010 | Anal. Chem. | pmid:20704384 |
| Yuan Y et al. | A signal-on electrochemical probe-label-free aptasensor using gold-platinum alloy and stearic acid as enhancers. | 2010 | Biosens Bioelectron | pmid:20708400 |
| Jun HY et al. | Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. | 2010 | Acad Radiol | pmid:19815430 |
| Jian WX et al. | [Detection and analysis on plasma metabolomics in patient with coronary heart disease of Xin-blood stasis syndrome pattern]. | 2010 | Zhongguo Zhong Xi Yi Jie He Za Zhi | pmid:20815270 |
| Lai TY et al. | Alterations in serum fatty acid concentrations and desaturase activities in Bietti crystalline dystrophy unaffected by CYP4V2 genotypes. | 2010 | Invest. Ophthalmol. Vis. Sci. | pmid:19797200 |
| Zhang Y et al. | The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity. | 2010 | J. Lipid Res. | pmid:19609006 |
| Romanowicz L and Bańkowski E | Altered sphingolipid composition in Wharton's jelly of pre-eclamptic newborns. | 2010 | Pathobiology | pmid:20332667 |
| Thomas CP et al. | Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. | 2010 | J. Biol. Chem. | pmid:20061396 |
| Valencia-Chamorro SA et al. | Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. | 2010 | J. Food Sci. | pmid:21535515 |