stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Iot T et al. | Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes. | 1975 | Biochemistry | pmid:167814 |
Phadke RS | Sedimentation test for procaine benzylpenicillin in oil with aluminium monostearate. III. Substitution of the sedimentation rate for the blood-level duration test of WHO in rabbits. | 1975 Aug-Nov | Hindustan Antibiot Bull | pmid:1236093 |
Sabbah A | [Letter: Immunodepressive action of erythromycin ethyl-succinate and erythromycin stearate. Study by the lymphoblastic transformation test and natural and rheumatoid rosette test]. | 1976 | Nouv Presse Med | pmid:1264643 |
Lundberg B | Thermal properties of systems containing cholesteryl esters and triglycerides. | 1976 | Acta Chem. Scand., B, Org. Chem. Biochem. | pmid:1266525 |
Pickart LR and Thaler MM | Free fatty acids and albumin as mediators of thrombin-stimulated fibrinogen synthesis. | 1976 | Am. J. Physiol. | pmid:1267031 |
Musty PR and Nickless G | Extractants for organochlorine insecticides and polychlorinated biphenyls from water. | 1976 | J. Chromatogr. | pmid:818099 |
Soler-Argilaga C et al. | The effect of sex on the quantity and properties of the very low density lipoprotein secreted by the liver in vitro. | 1976 | J. Lipid Res. | pmid:178815 |
Uyesaka N et al. | Lanthanum and some other cation-induced changes in fluidity of synaptosomal membrane studied with nitroxide stearate spin labels. | 1976 | J. Membr. Biol. | pmid:181579 |
Miller RW and De La Roche IA | Properties of spin labelled membranes of Fusarium oxysporum f. sp. lycopersici. | 1976 | Biochim. Biophys. Acta | pmid:182261 |
Ruf HH and Gratzl M | Binding of nitroxide stearate spin labels to bovine serum albumin. | 1976 | Biochim. Biophys. Acta | pmid:184832 |
Todorow S and Elies W | [Oily contrast medium in liquor space following myelography. A clinical-radiological study on extent, velocity and ways of elimination of monoiodine stearate]. | 1976 | Neurochirurgia (Stuttg) | pmid:185538 |
Marai L et al. | Identification of isomeric doxyl stearic acids by gas-liquid chromatography and mass spectrometry. | 1976 | Chem. Phys. Lipids | pmid:186203 |
Zenser TV et al. | Spin-labeled stearates as probes for microenvironment of murine thymocyte adenylate cyclase-cyclic adenosine 3':5'-monophosphate system. | 1976 | J. Biol. Chem. | pmid:187588 |
Koroly MJ and Conner RL | Unsaturated fatty acid biosynthesis in Tetrahymena. Evidence for two pathways. | 1976 | J. Biol. Chem. | pmid:826532 |
Waring AJ et al. | In vivo modification of plant membrane phospholipid composition. | 1976 | Biochim. Biophys. Acta | pmid:953014 |
Björkhem I | On the mechanism of regulation of omega oxidation of fatty acids. | 1976 | J. Biol. Chem. | pmid:956185 |
Steffen DG and Platner WS | Subcellular membrane fatty acids of rat heart after cold acclimation or thyroxine. | 1976 | Am. J. Physiol. | pmid:961919 |
Adachi H et al. | Effect of long-chain acyl-CoA on the omega-oxidation of monocarboxylic acid. | 1976 | Hokkaido Igaku Zasshi | pmid:985795 |
Porra RJ and Stumpf PK | Lipid biosynthesis in developing and germinating soybean cotyledons. The formation of palmitate and stearate by chopped tissue and supernatant preparations. | 1976 | Arch. Biochem. Biophys. | pmid:987755 |
Weber J et al. | [Can zinc stearate cause lung fibrosis? (Case report)]. | 1976 | Beitr Silikoseforsch Pneumokoniose | pmid:990095 |
Yamashita T et al. | [Studies on erythromycin stearate capsules (OE-7) (author's transl)]. | 1976 | Jpn J Antibiot | pmid:933342 |
Thies C | Development of injectable microcapsules for use in the treatment of narcotic addiction. | 1976 | Natl Inst Drug Abuse Res Monogr Ser | pmid:967230 |
Gray AP and Guardina WJ | Long-acting narcotic antagonist complexes. | 1976 | Natl Inst Drug Abuse Res Monogr Ser | pmid:967231 |
Eliasz AW et al. | Phospholipid phase transitions. Effects of n-alcohols, n-monocarboxylic acids, phenylalkyl alcohols and quaternary ammonium compounds. | 1976 | Biochim. Biophys. Acta | pmid:971432 |
Graham KC et al. | Simple thin-layer chromatographic identification method for erythromycin stearate. | 1976 | J. Chromatogr. | pmid:977688 |
Matsuda Y et al. | Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. | 1976 | J Pharm Sci | pmid:978434 |
Caster WO et al. | Effect of dietary palmitate, stearate, oleate and linoleate on the tissue lipid and systolic blood pressure of the rat. | 1976 | Int J Vitam Nutr Res | pmid:1010686 |
Brown ST | Treatment of secondary syphilis. | 1976 | J Am Vener Dis Assoc | pmid:1010778 |
Hannuksela M et al. | Contact sensitivity to emulsifiers. | 1976 | Contact Derm. | pmid:1021350 |
Horhota ST et al. | Effect of storage at specified temperature and humidity on properties of three directly compressible tablet formulations. | 1976 | J Pharm Sci | pmid:1032656 |
Shen WW et al. | Effect of nonionic surfactants on percutaneous absorption of salicylic acid and sodium salicylate in the presence of dimethyl sulfoxide. | 1976 | J Pharm Sci | pmid:1032661 |
Müller WE | The use of 8-anilino-1-naphthalenesulfonic acid as a reporter group molecule for circular dichroism and fluorescence measurements. The effect of stearic acid and sodium dodecylsulfate on the conformation of bovine and human serum albumin. | 1976 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:1033907 |
Whorton AR et al. | The metabolism of (1-14C) stearic acid in rat testicular tissue. | 1976 | Biochim. Biophys. Acta | pmid:1252481 |
Fee JV et al. | Influence of hydrophobic materials on dissolution of a nondisintegrating hydrophilic solid (potassium chloride). | 1976 | J Pharm Sci | pmid:1255446 |
Yamashita T et al. | [Blood concentration and urinary excretion in human of OE-7, a gastric hard capsule containing enteric-coated granules. I (author's transl)]. | 1976 | Jpn J Antibiot | pmid:1263346 |
Agarwal HC and Nair AM | Studies on the cholesterol ester hydrolase of Trogoderma (Coleoptera). | 1976 | Biochem. J. | pmid:962852 |
Thompson W and MacDonald G | Cytidine diphosphate diglyceride of bovine brain. Positional distribution of fatty acids and analysis of major molecular species. | 1976 | Eur. J. Biochem. | pmid:776622 |
Warhurst DC et al. | The chemotherapy of rodent malaria, XXIV. The blood schizontocidal action of erythromycin upon Plasmodium berghei. | 1976 | Ann Trop Med Parasitol | pmid:788656 |
Boggiano BG and Gleeson M | Gastric acid inactivation of erythromycin stearate in solid dosage forms. | 1976 | J Pharm Sci | pmid:5588 |
Ahmed M and Enever RP | Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [proceedings]. | 1976 | J. Pharm. Pharmacol. | pmid:12326 |
Norwitz G and Galan M | Determination of barium and strontium peroxides (active oxygen) in igniters in small-arms tracer ammunition. | 1976 | Talanta | pmid:18961958 |
Moës A | [Influence of the addition of aluminium stearate and of colloidal silica on the properties of rectal suppositories formulations (author's transl)]. | 1976 Jul-Aug | J Pharm Belg | pmid:185351 |
Uyesaka N | Lanthanum and some other cation-induced changes in fluidity of synaptosomal membrane studied with nitroxide stearate spin labels. J. Membrane Biol. 27:283. | 1977 | J. Membr. Biol. | pmid:190405 |
Galpin JR and Allen JC | The influence of micelle formation on lipoxygenase kinetics. | 1977 | Biochim. Biophys. Acta | pmid:409436 |
Bolton P and Harwood JL | Some characteristics of soluble fatty acid synthesis in germinating pea seeds. | 1977 | Biochim. Biophys. Acta | pmid:20971 |
Rowe RC | The adhesion of film coatings to tablet surfaces--the effect of some direct compression excipients and lubricants. | 1977 | J. Pharm. Pharmacol. | pmid:22617 |
Sixsmith D | The properties of tablets containing microcrystalline cellulose. | 1977 | J. Pharm. Pharmacol. | pmid:15069 |
Newton JM and Razzo FN | The in vitro bioavailability of various drugs formulated as hard gelatin capsules. | 1977 | J. Pharm. Pharmacol. | pmid:17668 |
Newton JM and Razzo FN | The influence of additives on the presentation of a drug in hard gelatin capsules. | 1977 | J. Pharm. Pharmacol. | pmid:17694 |
Donaldson RP and Beevers H | Lipid composition of organelles from germinating castor bean endosperm. | 1977 | Plant Physiol. | pmid:16659829 |