stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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Simões AP et al. | Incorporation of free fatty acids can explain alterations in the molecular species composition of phosphatidylcholine and phosphatidylethanolamine in human erythrocytes as induced by Plasmodium falciparum. | 1992 | Cell Biol. Int. Rep. | pmid:1327542 |
TOVE SB et al. | Turnover of palmitic, stearic, and unsaturated fatty acids in rat liver. | 1956 | J. Biol. Chem. | pmid:13278335 |
MEAD JF et al. | Metabolism of the essential fatty acids. II. The metabolism of stearate, oleate, and linoleate by fat-deficient and normal mice. | 1956 | J. Biol. Chem. | pmid:13278347 |
MUNZEL K and AMMANN R | [Contributions on the character of water-soluble fatty ointments. X. Quasiviscosity determination of stearate ointments]. | 1955 | Pharm Acta Helv | pmid:13289260 |
Fanjul LF et al. | Diacylglycerol rather than Ca2+ mediates GnRH inhibition of FSH induced steroidogenesis in ovarian granulosa cells. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1329745 |
GLASCOCK RF and REINIUS LR | Studies on the origin of milk fat. 1. The location of tritium in stearic acid produced by the catalytic addition of tritium to elaidic acid. | 1956 | Biochem. J. | pmid:13315207 |
JAMES AT and MARTIN AJ | Gas-liquid chromatography: the separation and identification of the methyl esters of saturated and unsaturated acids from formic acid to n-octadecanoic acid. | 1956 | Biochem. J. | pmid:13315260 |
BLOMSTRAND R et al. | On the intestinal absorption of 2, 2-dimethylstearic acid fed as free acid or as glyceride. | 1956 | Acta Physiol. Scand. | pmid:13339456 |
KERN W et al. | [Suggestions for the composition of the general section on ointments and salve bases and emulsifiers in the German Pharmacopeia (DAB 6, Annex). II]. | 1956 | Hautarzt | pmid:13345190 |
COOKE NJ et al. | The branched-chain fatty acids of mutton fat. 3. The isolation of 16-methylheptadecanoic acid (isostearic acid). | 1956 | Biochem. J. | pmid:13363830 |
HUME JC and FACIO G | An analysis of the results of the treatment of yaws with a single injection of procaine penicillin with 2% aluminium monostearate. | 1956 | Bull. World Health Organ. | pmid:13404472 |
Buensod M and Favarger P | [Observations on the digestibility of palmitic and stearic acids and their glyceric esters in rats]. | 1956 | Helv Physiol Pharmacol Acta | pmid:13405350 |
BRZEZINSKI A et al. | Prolonged effect of riboflavin: aluminum monostearate suspensions in man. | 1957 | J Am Pharm Assoc Am Pharm Assoc | pmid:13438726 |
KARVINEN E et al. | Effect of palmitic and stearic acid on cholesterol absorption in man. | 1957 | J Appl Physiol | pmid:13462909 |
FABER JS | A note on the assay of zinc stearate. | 1957 | J Am Pharm Assoc Am Pharm Assoc | pmid:13491438 |
Rafi MA et al. | Correction of sulfatide metabolism after transfer of prosaposin cDNA to cultured cells from a patient with SAP-1 deficiency. | 1992 | Am. J. Hum. Genet. | pmid:1350885 |
RUTSTEIN DD et al. | Effects of linolenic and stearic acids on cholesterol-induced lipoid deposition in human aortic cells in tissue-culture. | 1958 | Lancet | pmid:13515277 |
COX AJ and DEEDS F | Dietary production of lipogranuloma in rats. | 1958 Mar-Apr | Am. J. Pathol. | pmid:13520907 |
DAWSON RM | The labelling of ram semen in vivo with radioactive phosphate and [carboxy-14C] stearic acid. | 1958 | Biochem. J. | pmid:13522653 |
HARDING HE | Some enquiries into the toxicology of zinc stearate. | 1958 | Br J Ind Med | pmid:13523087 |
Holian O and Nelson R | Action of long-chain fatty acids on protein kinase C activity: comparison of omega-6 and omega-3 fatty acids. | 1992 May-Jun | Anticancer Res. | pmid:1352441 |
CONIGLIO JG and CATE DL | The distribution and biosynthesis of palmitic and stearic acids in liver, intestine, and carcass of intact normal and fasted rats. | 1958 | J. Biol. Chem. | pmid:13549425 |
KELLERSHOHN C and BENICHOUX R | [Comparative study of the drainage through the lymphatic vessels of a radioactive fat, ethyl diiodosterate labeled with I 131, and a radioactive colloidal substance, colloidal gold 198]. | 1958 May-Jun | Minerva Nucl | pmid:13565747 |
LONG CL et al. | Studies on absorption and metabolism of propylene glycol distearate. | 1958 | Arch. Biochem. Biophys. | pmid:13584006 |
LONG CL et al. | An investigation of the in vivo hydrolysis and absorption of propylene glycol distearate. | 1958 | Arch. Biochem. Biophys. | pmid:13584007 |
Fatani W and Rosen D | Irradiation of Langmuir-Blodgett multilayer preparations of phospholipids and a fatty acid. 1: Effect of UV radiation. | 1992 | Int. J. Radiat. Biol. | pmid:1362756 |
Fatani W and Rosen D | Irradiation of Langmuir-Blodgett multilayer preparations of phospholipids and a fatty acid. 2: Effect of X-radiation. | 1992 | Int. J. Radiat. Biol. | pmid:1362757 |
BLOMSTRAND R et al. | Asymmetric incorporation of linoleic acid-1-C14 and stearic acid-1-C14 into human lymph lecithins during fat absorption. | 1959 | Proc. Soc. Exp. Biol. Med. | pmid:13645714 |
GERSHFELD NL and SHANES AM | Antagonism of veratrine by calcium ion in monolayers of stearic acid. | 1959 | Science | pmid:13658972 |
FITZHUGH OG et al. | Chronic oral toxicities of four stearic acid emulsifiers. | 1959 | Toxicol. Appl. Pharmacol. | pmid:13659539 |
SKIPSKI VP et al. | Identification of 2-hydroxystearic acid in spinal cord phrenosine by chromatographic separation of hydroxy fatty acids. | 1959 | Arch. Biochem. Biophys. | pmid:13661981 |
SHANES AM and GERSHFELD NL | Interactions of veratrum alkaloids, procaine, and calcium with monolayers of stearic acid and their implications for pharmacological action. | 1960 | J. Gen. Physiol. | pmid:13750673 |
Bengochea LA et al. | Changes in microsomal phospholipid fatty acids composition in cholestatic rats. | 1992 Mar-Apr | Arch Int Physiol Biochim Biophys | pmid:1379485 |
AGARWAL SC et al. | Blood-level duration limit test of procaine benzylpenicillin in sheep. | 1961 | Bull. World Health Organ. | pmid:13859560 |
KUNUGI K | Studies on the syntheses of sucrose fatty acid esters. II. Separation of the alcoholyses products by liquid column chromatography and determination of the contents of sucrose monostearate. | 1963 | Chem. Pharm. Bull. | pmid:13927387 |
KUNUGI K | Studies on the syntheses of sucrose fatty acid esters. III. Re-esterification of sucrose monostearate. | 1963 | Chem. Pharm. Bull. | pmid:13927388 |
NAKAGAKI M and NISHINO M | [Studies on the physicochemical properties of aluminum soap. II. Structural viscosity of aluminum stearate in benzene]. | 1963 | Yakugaku Zasshi | pmid:13937343 |
NIELSEN K and SCHMIDT H | [Should the standard treatment of gonorrhea be changed? Effects of the treatment of gonorrhea in 1960 in ambulant and hospitalized patients]. | 1962 | Manedsskr Prakt Laegegern | pmid:13938514 |
OSTWALD R | Fat content and fatty acids in some commercial mixes for baked products. | 1963 | J Am Diet Assoc | pmid:13940620 |
GUTIERREZ J et al. | Lipid metabolism of rumen ciliates and bacteria. I. Uptake of fatty acids by Isotricha prostoma and Entodinium simplex. | 1962 | Appl Microbiol | pmid:13951437 |
HALL PF et al. | Synthesis of fatty acids by testicular tissue in vitro. | 1963 | Can J Biochem Physiol | pmid:13952129 |
HUEPER WC and PAYNE WW | Polyoxyethylene(8)stearate. Carcinogenic studies. | 1963 | Arch. Environ. Health | pmid:13955486 |
JAMES AT | [Studies on the biosynthesis of 18 carbon mono-and tri-unsaturated fatty acids by gas phase chromatography]. | 1962 | Bull. Soc. Chim. Biol. | pmid:13957228 |
FOSSA T | [Inhibition of hepatic glucose-6-phosphatase by fatty acids and zinc ions]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13958874 |
FOTI L et al. | [In vitro liver biosynthesis of cholesterol from acetate, stearate and linoleate 1-C-14]. | 1961 | Boll. Soc. Ital. Biol. Sper. | pmid:13958917 |
BARGONI N and SISINI A | [Inhibition and reactivation of the hydrolases of digestion]. | 1962 | Boll. Soc. Ital. Biol. Sper. | pmid:13966663 |
BIOZZI G et al. | [Stimulation and depression of the phagocytic function of the reticuloendothelial system by lipid emulsions. Relation to some immunological phenomena]. | 1963 | Rev Fr Etud Clin Biol | pmid:13968394 |
BONE GJ and PARENT G | Stearic acid, an essential growth factor for Trypanosoma cruzi. | 1963 | J. Gen. Microbiol. | pmid:13968755 |
BONSER GM et al. | A further study of bladder implantation in the mouse as a means of detecting carcinogenic activity: use of crushed paraffin wax or stearic acid as the vehicle. | 1963 | Br. J. Cancer | pmid:13968883 |
BAKER RW et al. | Fatty-acid composition of brain lecithins in multiple sclerosis. | 1963 | Lancet | pmid:13969172 |
ROSENBERG MD | Cell guidance by alterations in monomolecular films. | 1963 | Science | pmid:13974905 |
TROUT DL and ESTES EH | Factors affecting liver uptake of serum free stearic acid-1-C14. | 1962 | Am. J. Physiol. | pmid:13994303 |
WALLEN LL et al. | The microbiological production of 10-hydroxystearic acid from oleic acid. | 1962 | Arch. Biochem. Biophys. | pmid:13998583 |
WELD JT et al. | Production of octadecenoic acid in plasma by Staphylococcus aureus. | 1963 | Proc. Soc. Exp. Biol. Med. | pmid:13999824 |
CREASEY WA | Observations on the activation of stearic acid by rat-liver preparations. | 1962 | Biochim. Biophys. Acta | pmid:14023748 |
DAVIDOFF F and KORN ED | Synthesis of unsaturated fatty acids in the cellular slime mold. | 1962 | Biochem. Biophys. Res. Commun. | pmid:14025332 |
DEMPSKI RE et al. | Permeability of excised human keratin to lipid-soluble substances. II. | 1963 | J Pharm Sci | pmid:14026933 |
DEYKIN D and GOODMAN DS | The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. | 1962 | J. Biol. Chem. | pmid:14027461 |
KAUNITZ H et al. | Studies of the generalized Shwartzman reaction produced by diet. IV. Ethyl ester fractions of cod liver oil and dihydroxystearic acid. | 1963 | Metab. Clin. Exp. | pmid:14031428 |
Komata Y et al. | In vitro percutaneous absorption of thiamine disulfide from a mixture of propylene glycol and fatty acid. | 1992 | J Pharm Sci | pmid:1403716 |
JOHNSON RC and GARY ND | NUTRITION OF LEPTOSPIRA POMONA. II. FATTY ACID REQUIREMENTS. | 1963 | J. Bacteriol. | pmid:14044026 |
EDWARDS CH et al. | CHROMATOGRAPHY ON COMPOUNDS OF BIOLOGICAL INTEREST OF GLASS FIBER, PARAFFIN-COATED, AND UNTREATED CELLULOSE PAPER. | 1963 | J. Chromatogr. | pmid:14045492 |
LAMBIOTTE M | [USE OF RADIOACTIVE CHOLESTEROL IN THE STUDY OF THE INFLUENCE OF DIETARY LIPIDS ON CHOLESTEROL METABOLISM]. | 1963 | Ann Nutr Aliment | pmid:14048747 |
BLOMSTRAND R et al. | BIOHYDROGENATION IN GERM-FREE RATS. | 1963 Jul-Aug | J Atheroscler Res | pmid:14051792 |
ULLMANN E et al. | [STUDIES ON THE STABILITY OF PENICILLIN G SODIUM IN THE PRESENCE OF IONOGENIC TENSIDES, ORGANIC GEL FORMERS AND PRESERVATIVE AGENTS. 7. COMMUNICATION ON THE INFLUENCE OF ADJUVANTS IN DRUG COMPOUNDING]. | 1963 Jul-Aug | Pharm Acta Helv | pmid:14052353 |
SHIFRINE M and MARR AG | THE REQUIREMENT OF FATTY ACIDS BY PITYROSPORUM OVALE. | 1963 | J. Gen. Microbiol. | pmid:14053273 |
SOLOFF LA and WIEDEMAN MP | BIOMICROSCOPIC OBSERVATIONS ON VASOCONSTRICTIVE AND THROMBOGENIC EFFECTS PRODUCED BY LONG-CHAIN SATURATED FATTY ACIDS WITHIN THE VASCULATURE OF THE WING OF AN UNANAESTHETIZED BAT. | 1963 | Nature | pmid:14058613 |
ROUS S and FAVARGER P | [ROLE OF DEGRADATION IN THE MAINTENANCE OF THE COMPOSITION OF RESERVE FATTY ACIDS]. | 1963 | Helv Physiol Pharmacol Acta | pmid:14058926 |
Ashes JR et al. | Incorporation of n-3 fatty acids of fish oil into tissue and serum lipids of ruminants. | 1992 | Lipids | pmid:1406074 |
GOMPERTZ SM and SAMMONS HG | THE ORIGIN OF FAECAL LIPIDS. THE COMPOSITION OF FAECAL FATSIN HUMAN SUBJECTS. | 1963 | Clin. Chim. Acta | pmid:14063975 |
HEALD PJ and BADMAN HG | LIPID METABOLISM AND THE LAYING HEN. I. PLASMA-FREE FATTY ACIDS AND THE ONSET OF LAYING IN THE DOMESTIC FOWL. | 1963 | Biochim. Biophys. Acta | pmid:14067611 |
KERR SE and READ WW | THE FATTY ACID COMPONENTS OF POLYPHOSPHOINOSITIDE PREPARED FROM CALF BRAIN. | 1963 | Biochim. Biophys. Acta | pmid:14067624 |
MORRIS LJ | SEPARATION OF ISOMERIC LONG-CHAIN POLYHYDROXY ACIDS BY THIN-LAYER CHROMATOGRAPHY. | 1963 | J. Chromatogr. | pmid:14070998 |
MAHADEVAN S et al. | STUDIES ON METABOLISM OF VITAMIN A. 3. THE MODE OF ABSORPTION OF VITAMIN A ESTERS IN THE LIVING RAT. | 1963 | Biochem. J. | pmid:14071526 |
MAHADEVAN S et al. | STUDIES ON METABOLISM OF VITAMIN A. 4. STUDIES ON THE MODE OF ABSORPTION OF VITAMIN A BY RAT INTESTINE IN VITRO. | 1963 | Biochem. J. | pmid:14071527 |
CORRIN B | ALUMINIUM PNEUMOCONIOSIS. I. IN VITRO COMPARISON OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND A GRANULAR ALUMINIUM POWDER. | 1963 | Br J Ind Med | pmid:14072616 |
CORRIN B | ALUMINIUM PNEUMOCONIOSIS. II. EFFECT ON THE RAT LUNG OF INTRATRACHEAL INJECTIONS OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND OF A GRANULAR ALUMINIUM POWDER. | 1963 | Br J Ind Med | pmid:14072617 |
KORN ED and GREENBLATT CL | SYNTHESIS OF ALPHA-LINOLENIC ACID BY LEISHMANIA ENRIETTII. | 1963 | Science | pmid:14074842 |
KUNUGI K | STUDIES ON THE SYNTHESES OF SUCROSE FATTY ACID ESTERS. IV. VELOCITY OF ALCOHOLYSIS REACTION. | 1963 | Chem. Pharm. Bull. | pmid:14075263 |
PANDE SV et al. | MICRODETERMINATION OF LIPIDS AND SERUM TOTAL FATTY ACIDS. | 1963 | Anal. Biochem. | pmid:14077635 |
BURNS TW et al. | EFFECT OF INSULIN ON PLASMA FREE FATTY ACIDS OF NORMAL SUBJECTS. | 1963 | J. Lab. Clin. Med. | pmid:14080865 |
CHAKRAVORTI KP and SADHU DP | STUDIES ON CHEMICAL COMPOSITION OF PROTEIN AND FAT IN THE OVIDUCT OF THE PIGEON, COLUMBA LIVIA GMELIN. | 1963 | Ann Biochem Exp Med | pmid:14082710 |
STEIN O and STEIN Y | METABOLISM OF FATTY ACIDS IN THE ISOLATED PERFUSED RAT HEART. | 1963 | Biochim. Biophys. Acta | pmid:14085937 |
ERWIN J and BLOCH K | POLYUNSATURATED FATTY ACIDS IN SOME PHOTOSYNTHETIC MICROORGANISMS. | 1963 | Biochem Z | pmid:14087318 |
LEVY G and GUMTOW RH | EFFECT OF CERTAIN TABLET FORMULATION FACTORS ON DISSOLUTION RATE OF THE ACTIVE INGREDIENT. III. TABLET LUBRICANTS. | 1963 | J Pharm Sci | pmid:14088962 |
LEFEBVRE P and HENRIOUL F | [INFLUENCE OF GLUCAGON ON THE BLOOD LEVEL AND ARTERIO-VENOUS DIFFERENCE OF UNESTERIFIED FATTY ACIDS]. | 1963 Sep-Oct | Ann. Endocrinol. (Paris) | pmid:14092350 |
NAKAGAKI M and NISHINO M | [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF ALUMINUM SOAPS. III. COMPOSITION OF ALUMINUM STEARATE AND STRUCTURAL VISCOSITY OF BENZENE SOLUTION]. | 1963 | Yakugaku Zasshi | pmid:14094211 |
NAKAGAKI M and NISHINO M | [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF ALUMINUM SOAPS. IV. EFFECT OF THERMAL TREATMENT ON THE STRUCTURE OF THE SOAP]. | 1963 | Yakugaku Zasshi | pmid:14094212 |
LEAT WM | FATTY ACID COMPOSITION OF THE SERUM LIPIDS OF PIGS GIVEN DIFFERENT AMOUNTS OF LINOLEIC ACID. | 1963 | Biochem. J. | pmid:14097364 |
FLEMMING K | RADIATION PROTECTIVE EFFECT AND PHARMACOLOGICALLY CHANGED ACTIVITY OF THE RETICULO-ENDOTHELIAL SYSTEM. | 1963 | Nature | pmid:14098457 |
SHORE PA and ALPERS HS | PLATELET DAMAGE INDUCED IN PLASMA BY CERTAIN FATTY ACIDS. | 1963 | Nature | pmid:14098491 |
YOUNG RJ and GARRETT RL | EFFECT OF OLEIC AND LINOLEIC ACIDS ON THE ABSORPTION OF SATURATED FATTY ACIDS IN THE CHICK. | 1963 | J. Nutr. | pmid:14100991 |
SALAZAR H | DIETHYLENE GLYCOL DISTEARATE EMBEDDING AND ULTRAMICROTOME SECTIONING FOR LIGHT MICROSCOPY. | 1964 | Stain Technol | pmid:14106797 |
DUPUIS G and FAVARGER P | [RESEARCH ON THE SYNTHESIS OF FATTY ACIDS. XII. THE SYNTHESIS OF OLEIC ACID IN THE MOUSE]. | 1963 | Helv Physiol Pharmacol Acta | pmid:14107835 |
ROUS S and FAVARGER P | [RESEARCH ON THE SYNTHESIS OF FATTY ACIDS. XIV. INFLUENCE OF THE COMPOSITION OF THE RESERVES ON THE SYNTHESIS OF DIFFERENT FATTY ACIDS IN THE MOUSE]. | 1963 | Helv Physiol Pharmacol Acta | pmid:14107841 |
KORN ED | FATTY ACIDS OF ACANTHAMOEBA SP. | 1963 | J. Biol. Chem. | pmid:14109190 |
KRITCHEVSKY D | EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS FED CHOLESTEROL-FREE DIETS. | 1964 Jan-Feb | J Atheroscler Res | pmid:14112225 |
VROMAN L | EFFECTS OF HYDROPHOBIC SURFACES UPON BLOOD COAGULATION. | 1964 | Thromb Diath Haemorrh | pmid:14113384 |
BJOERNTORP P et al. | ALBUMIN ANTAGONISM OF FATTY ACID EFFECTS ON OXIDATION AND PHOSPHORYLATION REACTIONS IN RAT LIVER MITOCHONDRIA. | 1964 | J. Biol. Chem. | pmid:14114863 |
BENJAMIN W and GELLHORN A | THE EFFECT OF DIABETES AND INSULIN ON THE BIOSYNTHESIS OF INDIVIDUAL FATTY ACIDS IN ADIPOSE TISSUE. | 1964 | J. Biol. Chem. | pmid:14114873 |