stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Ebube NK et al. | Application of near-infrared spectroscopy for nondestructive analysis of Avicel powders and tablets. | 1999 | Pharm Dev Technol | pmid:10027209 |
Zuurman K et al. | Effect of magnesium stearate on bonding and porosity expansion of tablets produced from materials with different consolidation properties. | 1999 | Int J Pharm | pmid:10053207 |
Rukkwamsuk T et al. | Hepatic fatty acid composition in periparturient dairy cows with fatty liver induced by intake of a high energy diet in the dry period. | 1999 | J. Dairy Sci. | pmid:10068949 |
Woldseth B et al. | Monounsaturated trans fatty acids, elaidic acid and trans-vaccenic acid, metabolism and incorporation in phospholipid molecular species in hepatocytes. | 1998 | Scand. J. Clin. Lab. Invest. | pmid:10088200 |
Caster WO et al. | Effect of dietary palmitate, stearate, oleate and linoleate on the tissue lipid and systolic blood pressure of the rat. | 1976 | Int J Vitam Nutr Res | pmid:1010686 |
Brown ST | Treatment of secondary syphilis. | 1976 | J Am Vener Dis Assoc | pmid:1010778 |
Jarvis GN et al. | Isolation and characterization of two glycerol-fermenting clostridial strains from a pilot scale anaerobic digester treating high lipid-content slaughterhouse waste. | 1999 | J. Appl. Microbiol. | pmid:10196746 |
Hannuksela M et al. | Contact sensitivity to emulsifiers. | 1976 | Contact Derm. | pmid:1021350 |
Neumann D et al. | A comparison of sutures for adjustable strabismus surgery. | 1999 | J AAPOS | pmid:10221801 |
Huang S et al. | Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. | 1999 | Kidney Int. | pmid:10231436 |
Pharmaceutical Reimbursement Board; final maximum allowable cost (MAC) determinations for certain drug products--Health Care Financing Administration. Final notice. | 1982 | Fed Regist | pmid:10259800 | |
Horhota ST et al. | Effect of storage at specified temperature and humidity on properties of three directly compressible tablet formulations. | 1976 | J Pharm Sci | pmid:1032656 |
Shen WW et al. | Effect of nonionic surfactants on percutaneous absorption of salicylic acid and sodium salicylate in the presence of dimethyl sulfoxide. | 1976 | J Pharm Sci | pmid:1032661 |
Cavalli R et al. | Solid lipid nanoparticles as carriers of hydrocortisone and progesterone complexes with beta-cyclodextrins. | 1999 | Int J Pharm | pmid:10332075 |
Müller WE | The use of 8-anilino-1-naphthalenesulfonic acid as a reporter group molecule for circular dichroism and fluorescence measurements. The effect of stearic acid and sodium dodecylsulfate on the conformation of bovine and human serum albumin. | 1976 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:1033907 |
Jones AE et al. | Effect of fatty acid chain length and saturation on the gastrointestinal handling and metabolic disposal of dietary fatty acids in women. | 1999 | Br. J. Nutr. | pmid:10341674 |
Bardi L et al. | Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. | 1999 | Int. J. Food Microbiol. | pmid:10357281 |
Alava MA et al. | Fatty acid desaturation: effect of alphafetoprotein on alpha-linolenic acid conversion by fetal rat hepatocytes. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10359023 |
McKellop HA et al. | Effect of molecular weight, calcium stearate, and sterilization methods on the wear of ultra high molecular weight polyethylene acetabular cups in a hip joint simulator. | 1999 | J. Orthop. Res. | pmid:10376720 |