stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Coulomb B et al. | Biafine applied on human epidermal wounds is chemotactic for macrophages and increases the IL-1/IL-6 ratio. | 1997 | Skin Pharmacol. | pmid:9449167 |
Dave PC et al. | Calculating order parameter profiles utilizing magnetically aligned phospholipid bilayers for 2H solid-state NMR studies. | 2003 Sep-Nov | Solid State Nucl Magn Reson | pmid:12943910 |
Molloy PL and Eisenstadt JM | Erythromycin resistance in mouse L cells. | 1979 | Somatic Cell Genet. | pmid:531731 |
Stults BM et al. | Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. | 1983 | South. Med. J. | pmid:6857302 |
Cobb TK | Effects of dietary stearic acid on plasma cholesterol levels. | 1992 | South. Med. J. | pmid:1734530 |
Desudchit P et al. | Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men. | 1984 | Southeast Asian J. Trop. Med. Public Health | pmid:6441265 |
Liang L and Fang Y | Photoluminescence of a mixed Langmuir-Blodgett film of C(60) and stearic acid at room temperature. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17499018 |
Deb S et al. | Langmuir-Blodgett films of p-terphenyl in different matrices: evidence of dual excimer. | 2007 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17350881 |
Biswas S et al. | Formation of complex films with water-soluble CTAB molecules. | 2006 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16549387 |
Xu G and Fang Y | Studies of surface-enhanced Raman scattering of C60 Langmuir-Blodgett film on a new substrate. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17889595 |