stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
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Authors | Title | Published | Journal | PubMed Link |
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SKOU JC | Local anaesthetics. V. The action of local anaesthetics on monomolecular layers of stearic acid. | 1954 | Acta Pharmacol Toxicol (Copenh) | pmid:14398295 |
MUNZEL K and AMMANN R | [Washable oil-water ointments. V. Complex-emulsified ointments; differences between stearate- and complex-emulsified ointments]. | 1954 | Pharm Acta Helv | pmid:13194353 |
SCRIBANTE P and FAVARGER P | [Studies on digestibility of stearic acid and its glyceric esters in rat]. | 1954 | Helv Physiol Pharmacol Acta | pmid:13201008 |
DUNCOMBE WG and GLASCOCK RF | The contribution of dietary stearic acid to milk fat. | 1954 | Biochem. J. | pmid:13172205 |
BERGSTROM S et al. | Intestinal absorption and metabolism of 2:2-dimethylstearic acid in the rat. | 1954 | Biochem. J. | pmid:13230010 |
GLASCOCK RF and REINIUS LR | Location of tritium in stearic acid produced by catalytic tritiation of elaidic acid. | 1954 | Biochem. J. | pmid:13230049 |
SHAFER JK and SMITH CA | Treatment of early infectious syphilis with N,N'-dibenzylethylenediamine dipenicillin G; a second report. | 1954 | Bull. World Health Organ. | pmid:13182589 |
CSIPKE Z | [Advanced training in prescription filling]. | 1954 | Gyogyszeresz | pmid:24551927 |
VALADE P and COSTE E | [Toxicity of the organic lead salts; experimental study]. | 1953 | Arch Mal Prof | pmid:13149301 |
BUTCHER EO | Penetration of radioactive stearic acid into the skin of the rat. | 1953 | J. Invest. Dermatol. | pmid:13096866 |