stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Thiel WJ and Sberna FJ | Fluidized bed film coating of an interactive powder mixture to produce microencapsulated 2-5 microns particles. | 1986 | J. Pharm. Pharmacol. | pmid:2871149 |
Hattori T et al. | Attenuation by pentobarbital of free fatty acid and diacylglycerol liberation during global ischaemia in rat brain. | 1986 | Neurol. Res. | pmid:2871507 |
Catalá A | Stearic acid desaturation in rat liver microsomes: stimulation by fatty acid binding protein. | 1986 | Acta Physiol Pharmacol Latinoam | pmid:2876583 |
Gotoh K et al. | Effects of unsaturated fatty acids on the peroxisomal enzyme activities of Tetrahymena pyriformis. | 1986 | J. Biochem. | pmid:2880840 |
Crosby T et al. | Identification of ecdysone 22-long-chain fatty acyl esters in newly laid eggs of the cattle tick Boophilus microplus. | 1986 | Biochem. J. | pmid:3030275 |
Ginóbili de MartÃnez MS et al. | Asymmetry of diacylglycerol metabolism in rat cerebral hemispheres. | 1986 | J. Neurochem. | pmid:3083043 |
Smith DM and Waite M | Phospholipid metabolism in human neutrophil subfractions. | 1986 | Arch. Biochem. Biophys. | pmid:3083776 |
Singh H and Poulos A | A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. | 1986 | Arch. Biochem. Biophys. | pmid:3767370 |
Goto S et al. | [Role of metal stearates in preparation of Eudragit RS-microcapsules containing sulfamethizole by evaporation process in water phase]. | 1986 | Yakugaku Zasshi | pmid:3701600 |
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Wan LS and Choong YL | The effect of excipients on the penetration of liquid into tablets. | 1986 | Pharm Acta Helv | pmid:3725815 |
Oh-Hashi Y et al. | Temperature- and growth-phase-dependent changes in membrane fatty acid compositions of Brevibacterium ammoniagenes. | 1986 | Arch. Biochem. Biophys. | pmid:3729431 |
Carter-Dawson L et al. | Rhodopsin, 11-cis vitamin A, and interstitial retinol-binding protein (IRBP) during retinal development in normal and rd mutant mice. | 1986 | Dev. Biol. | pmid:3732615 |
Chowhan ZT and Chi LH | Drug-excipient interactions resulting from powder mixing. III: Solid state properties and their effect on drug dissolution. | 1986 | J Pharm Sci | pmid:3735096 |
Chowhan ZT and Chi LH | Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution. | 1986 | J Pharm Sci | pmid:3735097 |
Fujii T et al. | Effect of exogenous lipids incorporated into the membrane of human erythrocytes on its glucose transport activity. | 1986 | Biochem. Int. | pmid:3741447 |
Peura P et al. | The effect of ethanol on the release of free fatty acids from the brain in vivo; a study with push-pull cannula. | 1986 | Arch. Toxicol. Suppl. | pmid:3468932 |
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Bankson DD et al. | Determination of retinyl esters and retinol in serum or plasma by normal-phase liquid chromatography: method and applications. | 1986 | Clin. Chem. | pmid:3940733 |
Tabachnick M and Korcek L | Effect of long-chain fatty acids on the binding of thyroxine and triiodothyronine to human thyroxine-binding globulin. | 1986 | Biochim. Biophys. Acta | pmid:2869786 |
Uribe WR | Yaws in Colombia. | 1985 May-Jun | Rev. Infect. Dis. | pmid:4012172 |
Willcox RR | Mass treatment campaigns against the endemic treponematoses. | 1985 May-Jun | Rev. Infect. Dis. | pmid:4012173 |
Brown ST | Therapy for nonvenereal treponematoses: review of the efficacy of penicillin and consideration of alternatives. | 1985 May-Jun | Rev. Infect. Dis. | pmid:4012176 |
Noy N and Zakim D | Fatty acids bound to unilamellar lipid vesicles as substrates for microsomal acyl-CoA ligase. | 1985 | Biochemistry | pmid:2931113 |
Enk L et al. | High-dose depot-medroxyprogesterone acetate--effects on the fatty acid composition of serum lecithin and cholesterol ester. | 1985 | Gynecol. Oncol. | pmid:2933308 |
Canonico PL et al. | Arachidonate stimulates prolactin release in vitro: a role for the fatty acid and its metabolites as intracellular regulator(s) in mammotrophs. | 1985 | Endocrinology | pmid:2981065 |
Onoda T et al. | Antitumor activity of D-mannosamine in vitro: cytotoxic effect produced by mannosamine in combination with free fatty acids on human leukemia T-cell lines. | 1985 | Jpn. J. Clin. Oncol. | pmid:3877190 |
Shanson DC et al. | Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance. | 1985 | J. Antimicrob. Chemother. | pmid:3882657 |
Politi LE et al. | Dexamethasone effect on free fatty acid and diacylglycerol accumulation during experimentally induced vasogenic brain edema. | 1985 | Neurochem Pathol | pmid:3831846 |
Boiron F et al. | A comparison of substrate-dependent fatty acyl-CoA synthetase activities and ATP hydrolysis in membrane pellets from normal and trembler mouse sciatic nerves. | 1985 | Neurochem. Int. | pmid:20492990 |
Roughan PG | Phosphatidylglycerol and chilling sensitivity in plants. | 1985 | Plant Physiol. | pmid:16664127 |
Wood CB et al. | Reduction in the stearic to oleic acid ratio in the circulating red blood cells: a possible tumour marker in solid human neoplasms. | 1985 | Eur J Surg Oncol | pmid:4007173 |
Harrison GA et al. | Resistance in oral streptococci after repeated three-dose erythromycin prophylaxis. | 1985 | J. Antimicrob. Chemother. | pmid:4008379 |
Roblot L et al. | Effect of lubricant level and applied compressional pressure on surface friction of tablets. | 1985 | J Pharm Sci | pmid:4020661 |
Fujii M et al. | Fatty acid compositions of triacylglycerols and phospholipids in hen liver lipid before and after sexual maturity. | 1985 | Poult. Sci. | pmid:4022907 |
Carranco E et al. | Carbamazepine toxicity induced by concurrent erythromycin therapy. | 1985 | Arch. Neurol. | pmid:3977647 |
Ruwart MJ et al. | 16,16-Dimethyl PGE2 and fatty acids protect hepatocytes against CCl4-induced damage. | 1985 | In Vitro Cell. Dev. Biol. | pmid:4030626 |
Sklan D et al. | Digestion and absorption of lipids and bile acids in sheep fed stearic acid, oleic acid, or tristearin. | 1985 | J. Dairy Sci. | pmid:4031186 |
Bridges CD et al. | Vitamin A and interstitial retinol-binding protein in an eye with recessive retinitis pigmentosa. | 1985 | Invest. Ophthalmol. Vis. Sci. | pmid:4039711 |
Beckurts TE et al. | Kinetics of different 123I- and 14C-labelled fatty acids in normal and diabetic rat myocardium in vivo. | 1985 | Nucl Med Commun | pmid:4047532 |
Plachy J et al. | In vitro biopharmaceutical test for wetting rate. | 1985 | Acta Pharm Hung | pmid:4050448 |
Griffiths G et al. | The acylation of sn-glycerol 3-phosphate and the metabolism of phosphatidate in microsomal preparations from the developing cotyledons of safflower (Carthamus tinctorius L.) seed. | 1985 | Biochem. J. | pmid:4052051 |
Stubbs C et al. | Determination of erythromycin in serum and urine by high-performance liquid chromatography with ultraviolet detection. | 1985 | J Pharm Sci | pmid:4078714 |
Tse AG et al. | A glycophospholipid tail at the carboxyl terminus of the Thy-1 glycoprotein of neurons and thymocytes. | 1985 | Science | pmid:2865810 |
Crutchley DJ | Hydroxyeicosatetraenoic acids and other unsaturated fatty acids inhibit endotoxin-induced thromboplastin activity in human monocytes. | 1985 | Biochem. Biophys. Res. Commun. | pmid:2865954 |
Johansson ME | Influence of the granulation technique and starting material properties on the lubricating effect of granular magnesium stearate. | 1985 | J. Pharm. Pharmacol. | pmid:2867134 |
Staniforth JN | Relationship between particle packing and the physical stability of powder mixes. | 1985 | J. Pharm. Pharmacol. | pmid:2867136 |