stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Pedrazzi V et al. Tensile bond strength of a polymeric intra-buccal bioadhesive: the mucin role. 2001 Nov-Dec Boll Chim Farm pmid:11822242
Hong CY Discovery of gemifloxacin (Factive, LB20304a): a quinolone of a new generation. 2001 Jan-Feb Farmaco pmid:11347965
Kim JY et al. Lipid and fatty acid analysis of fresh and frozen-thawed immature and in vitro matured bovine oocytes. 2001 Reproduction pmid:11425337
Radwan SS et al. Effects of lipids on n-alkane attenuation in media supporting oil-utilizing microorganisms from the oily Arabian Gulf coasts. 2001 FEMS Microbiol. Lett. pmid:11430415
Yu HY et al. Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells. 2001 Diabetologia pmid:11380080
Chen H et al. Effect of cholesterol on miscibility and phase behavior in binary mixtures with synthetic ceramide 2 and octadecanoic acid. Infrared studies. 2001 Biochim. Biophys. Acta pmid:11406112
Morita YS and Englund PT Fatty acid remodeling of glycosyl phosphatidylinositol anchors in Trypanosoma brucei: incorporation of fatty acids other than myristate. 2001 Mol. Biochem. Parasitol. pmid:11420102
Kamm W et al. Analysis of steryl esters in cocoa butter by on-line liquid chromatography-gas chromatography. 2001 J Chromatogr A pmid:11407581
Hashimoto F et al. Accumulation of medium chain acyl-CoAs during beta-oxidation of long chain fatty acid by isolated peroxisomes from rat liver. 2001 Biol. Pharm. Bull. pmid:11411544
Hilpert B et al. Isolation and characterization of signal transduction mutants of Arabidopsis thaliana that constitutively activate the octadecanoid pathway and form necrotic microlesions. 2001 Plant J. pmid:11439130
Kushibiki S et al. Effect of beta-lactoglobulin on plasma retinol and triglyceride concentrations, and fatty acid composition in calves. 2001 J. Dairy Res. pmid:11928954
Haastrup A et al. Lipids stimulate the production of 6-keto-prostaglandin f(1alpha) in human dorsal hand veins. 2001 Hypertension pmid:11641299
Zeng F et al. [Analysis on infrared spectrum of human body gallstone with comparative method]. 2001 Guang Pu Xue Yu Guang Pu Fen Xi pmid:12947655
Chayabutra C et al. Rhamnolipid production by Pseudomonas aeruginosa under denitrification: effects of limiting nutrients and carbon substrates. 2001 Biotechnol. Bioeng. pmid:11084590
Nakanishi M et al. Characterisation of myogenic cell membrane: II. Dynamic changes in membrane lipids during the differentiation of mouse C2 myoblast cells. 2001 Cell Biol. Int. pmid:11589611
Patel S et al. Chemical and physical analyses of wax ester properties. 2001 J. Insect Sci. pmid:15455064
Zhang RJ et al. Self-organized lateral patterning of a rare earth complex and stearic acid in Langmuir films. 2001 Chemphyschem pmid:23696530
Liang X et al. Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction. 2001 J. Biol. Chem. pmid:11423543
Zhang L et al. Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element. 2001 Biochem. J. pmid:11415448
Montell E et al. DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11158925
Hannah VC et al. Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells. 2001 J. Biol. Chem. pmid:11085986
Lee I and Kadenbach B Palmitate decreases proton pumping of liver-type cytochrome c oxidase. 2001 Eur. J. Biochem. pmid:11737187
Raila J et al. Plasma transport and tissue distribution of beta-carotene, vitamin A and retinol-binding protein in domestic cats. 2001 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:11691620
Baines DL et al. Fatty acid modulation and sequence identity of fetal guinea pig alveolar type II cell amiloride-sensitive Na+ channel. 2001 Biochem. Biophys. Res. Commun. pmid:11676504
Boros LG and Williams RD Isofenphos induced metabolic changes in K562 myeloid blast cells. 2001 Leuk. Res. pmid:11532522
Pierri EG et al. Determination of oxamniquine in capsules by HPLC. 2001 J Pharm Biomed Anal pmid:11516919
Choo CY et al. The cytotoxicity and chemical constituents of the hexane fraction of Typhonium flagelliforme (Araceace). 2001 J Ethnopharmacol pmid:11483390
Bolhuis GK et al. DC calcium lactate, a new filler-binder for direct compaction of tablets. 2001 Int J Pharm pmid:11397569
DePeters EJ et al. Fatty acid and triglyceride composition of milk fat from lactating Holstein cows in response to supplemental canola oil. 2001 J. Dairy Sci. pmid:11352169
Korkishko YN et al. Characterization of alpha-phase soft proton-exchanged LiNbO3 optical waveguides. 2001 J Opt Soc Am A Opt Image Sci Vis pmid:11336221
Pacia SV et al. Biogenic amines in the human neocortex in patients with neocortical and mesial temporal lobe epilepsy: identification with in situ microvoltammetry. 2001 Brain Res. pmid:11311871
Fukui E et al. An in vitro investigation of the suitability of press-coated tablets with hydroxypropylmethylcellulose acetate succinate (HPMCAS) and hydrophobic additives in the outer shell for colon targeting. 2001 J Control Release pmid:11166411
Dean DD et al. Effect of polymer molecular weight and addition of calcium stearate on response of MG63 osteoblast-like cells to UHMWPE particles. 2001 J. Orthop. Res. pmid:11347688
Mizukoshi Y et al. Preparation of platinum nanoparticles by sonochemical reduction of the Pt(IV) ions: role of surfactants. 2001 Ultrason Sonochem pmid:11105315
Byrdwell WC et al. Triacylglycerol analysis of potential margarine base stocks by high-performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometry and flame ionization detection. 2001 J. Agric. Food Chem. pmid:11170612
Hatta I et al. X-ray diffraction study on ordered, disordered and reconstituted intercellular lipid lamellar structure in stratum corneum. 2001 Biophys. Chem. pmid:11254216
Alves MM et al. Effects of lipids and oleic acid on biomass development in anaerobic fixed-bed reactors. Part II: Oleic acid toxicity and biodegradability. 2001 Water Res. pmid:11257881
De Vriese SR et al. The composition of saturated fatty acids in plasma phospholipids changes in a way to counteract changes in the mean melting point during pregnancy. 2001 Lipids pmid:11214724
Wu J et al. Influence of wet granulation and lubrication on the powder and tableting properties of codried product of microcrystalline cellulose with beta-cyclodextrin. 2001 Eur J Pharm Biopharm pmid:11154905
Sakuma S et al. The effects of fatty acyl CoA esters on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11161586
Kita K et al. Characterization of the reversible nature of the reaction catalyzed by sphingolipid ceramide N-deacylase. A novel form of reverse hydrolysis reaction. 2001 Eur. J. Biochem. pmid:11168398
Thosar SS et al. A comparison of reflectance and transmittance near-infrared spectroscopic techniques in determining drug content in intact tablets. 2001 Pharm Dev Technol pmid:11247272
Höltje M et al. Molecular dynamics simulations of stratum corneum lipid models: fatty acids and cholesterol. 2001 Biochim. Biophys. Acta pmid:11248214
Sabir A et al. Formulation and process optimization to eliminate picking from market image tablets. 2001 Int J Pharm pmid:11250098
Nishioka Y and Yoshino H Lymphatic targeting with nanoparticulate system. 2001 Adv. Drug Deliv. Rev. pmid:11251245
Voinovich D et al. Melt pelletization in high shear mixer using a hydrophobic melt binder: influence of some apparatus and process variables. 2001 Eur J Pharm Biopharm pmid:11677073
Rahamatalla AB et al. Changes in fatty acids composition during seed growth and physicochemical characteristics of oil extracted from four safflower cultivars. 2001 Plant Foods Hum Nutr pmid:11678443
Maynar M et al. Menopause-induced changes in lipid fractions and total fatty acids in plasma. 2001 Endocr. Res. pmid:11678583
Bézaire V et al. Effects of fasting on muscle mitochondrial energetics and fatty acid metabolism in Ucp3(-/-) and wild-type mice. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11595653
Swaminathan V and Kildsig DO An examination of the moisture sorption characteristics of commercial magnesium stearate. 2001 AAPS PharmSciTech pmid:14727865
Carballeira NM et al. Identification and total synthesis of novel fatty acids from the Siphonarid limpet Siphonaria denticulata. 2001 J. Nat. Prod. pmid:11720525
Chen DB et al. In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel. 2001 Chem. Pharm. Bull. pmid:11724235
Finley JW and Davis CD Manganese absorption and retention in rats is affected by the type of dietary fat. 2001 Biol Trace Elem Res pmid:11697763
Mironova GD et al. Palmitic and stearic acids bind Ca2+ with high affinity and form nonspecific channels in black-lipid membranes. Possible relation to Ca2+-activated mitochondrial pores. 2001 J. Bioenerg. Biomembr. pmid:11710807
Glew RH et al. Fatty acid composition of the milk lipids of Nepalese women: correlation between fatty acid composition of serum phospholipids and melting point. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11728165
Shen Z et al. Fatty acid composition of lysophosphatidic acid and lysophosphatidylinositol in plasma from patients with ovarian cancer and other gynecological diseases. 2001 Gynecol. Oncol. pmid:11585410
Fomuso LB and Akoh CC Enzymatic modification of high-laurate canola to produce margarine fat. 2001 J. Agric. Food Chem. pmid:11559158
Moon YA et al. Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins. 2001 J. Biol. Chem. pmid:11567032
Takamoto DY et al. Stable ordering in Langmuir-Blodgett films. 2001 Science pmid:11509723
Wu P et al. Atemoyacin E, a bis-tetrahydrofuran annonaceous acetogenin from Annona atemoya seeds. 2001 J Asian Nat Prod Res pmid:11491392
Lalman JA and Bagley DM Anaerobic degradation and methanogenic inhibitory effects of oleic and stearic acids. 2001 Water Res. pmid:11471698
Mu YM et al. Saturated FFAs, palmitic acid and stearic acid, induce apoptosis in human granulosa cells. 2001 Endocrinology pmid:11459807
Ebba F et al. Stress relaxation studies of granules as a function of different lubricants. 2001 Eur J Pharm Biopharm pmid:11522488
Hunter KA et al. Effect of diets rich in oleic acid, stearic acid and linoleic acid on postprandial haemostatic factors in young healthy men. 2001 Br. J. Nutr. pmid:11502234
Gupta SV and Khosla P Palmitic and stearic acids similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. 2001 J. Nutr. pmid:11481404
Clouet P et al. Mitochondrial respiration on rumenic and linoleic acids. 2001 Biochem. Soc. Trans. pmid:11356175
Papanikolaou S et al. Kinetic profile of the cellular lipid composition in an oleaginous Yarrowia lipolytica capable of producing a cocoa-butter substitute from industrial fats. 2001 Antonie Van Leeuwenhoek pmid:11827207
Jensen RG et al. Parenteral infusion of a lactating woman with intralipid: changes in milk and plasma fatty acids. 2001 Adv. Exp. Med. Biol. pmid:11787679
Kuppuswamy R et al. Estimation of capping incidence by indentation fracture tests. 2001 AAPS PharmSci pmid:11741256
Otsuka M et al. Comparative evaluation of tableting compression behaviors by methods of internal and external lubricant addition: inhibition of enzymatic activity of trypsin preparation by using external lubricant addition during the tableting compression process. 2001 AAPS PharmSci pmid:11741271
Stehlin C et al. X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation. 2001 EMBO J. pmid:11689423
Andrès C et al. On the difficulty of assessing the specific surface area of magnesium stearate. 2001 Int J Pharm pmid:11337159
Ogwal S and Xide TU Bioavailability and stability of erythromycin delayed release tablets. 2001 Afr Health Sci pmid:12789122
Ves-Losada A et al. Incorporation and distribution of saturated and unsaturated fatty acids into nuclear lipids of hepatic cells. 2001 Lipids pmid:11337983
Fukui E et al. Effect of magnesium stearate or calcium stearate as additives on dissolution profiles of diltiazem hydrochloride from press-coated tablets with hydroxypropylmethylcellulose acetate succinate in the outer shell. 2001 Int J Pharm pmid:11274815
Kelly FD et al. A stearic acid-rich diet improves thrombogenic and atherogenic risk factor profiles in healthy males. 2001 Eur J Clin Nutr pmid:11305631
Oviedo JM et al. Pulmonary surfactant protein SP-B is significantly more immunoreactive in anionic than in zwitterionic bilayers. 2001 FEBS Lett. pmid:11311247
Ferreira JA et al. Hydrophobic interactions between spin-label 5-SASL and humic acid as revealed by ESR spectroscopy. 2001 Environ. Sci. Technol. pmid:11349289
Ghanouni P et al. Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor. 2001 Proc. Natl. Acad. Sci. U.S.A. pmid:11353823
Waddington E et al. Identification and quantitation of unique fatty acid oxidation products in human atherosclerotic plaque using high-performance liquid chromatography. 2001 Anal. Biochem. pmid:11355856
van den Bergh BA et al. Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements. 2001 Int J Pharm pmid:11292538
Ulmann L et al. Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats. 2001 Prostaglandins Leukot. Essent. Fatty Acids pmid:11334555
Habán P et al. Oleic acid serum phospholipid content is linked with the serum total- and LDL-cholesterol in elderly subjects. 2000 Nov-Dec Med. Sci. Monit. pmid:11208461
Pignatello R et al. In vitro release kinetics of Tolmetin from tabletted Eudragit microparticles. 2000 May-Jun J Microencapsul pmid:10819424
Le Hénaff M and Fontenelle C Chemical analysis of processing of spiralin, the major lipoprotein of Spiroplasma melliferum. 2000 May-Jun Arch. Microbiol. pmid:10896212
el-Mahdi IM and Deasy PB Tableting of coated ketoprofen pellets. 2000 Mar-Apr J Microencapsul pmid:10738689
Muller D et al. Niosomes as carriers of radiopaque contrast agents for X-ray imaging. 2000 Mar-Apr J Microencapsul pmid:10738698
Williams EE et al. The curvature and cholesterol content of phospholipid bilayers alter the transbilayer distribution of specific molecular species of phosphatidylethanolamine. 2000 Jul-Sep Mol. Membr. Biol. pmid:11128974
Bogataj M et al. The influence of magnesium stearate on the characteristics of mucoadhesive microspheres. 2000 Jul-Aug J Microencapsul pmid:10898089
Florin-Christensen J et al. Phosphatidylcholine formation is the predominant lipid biosynthetic event in the hemoparasite Babesia bovis. 2000 Mol. Biochem. Parasitol. pmid:10743618
Sun Y et al. [The study of the microwave reaction of stearic acid and pentyl amine]. 2000 Guang Pu Xue Yu Guang Pu Fen Xi pmid:12945403
Schmider W et al. Transport of heptafluorostearate across model membranes. Membrane transport of long-chain fatty acid anions I. 2000 J. Lipid Res. pmid:10787438
Wissing S et al. An investigation into the use of stepwise isothermal high sensitivity DSC as a means of detecting drug-excipient incompatibility. 2000 Int J Pharm pmid:10802407
Min Y et al. Pregnancy reduces arachidonic and docosahexaenoic in plasma triacylglycerols of Korean women. 2000 Int J Vitam Nutr Res pmid:10804459
Ahrabi SF et al. Influence of neutron activation factors on matrix tablets for site specific delivery to the colon. 2000 Eur J Pharm Sci pmid:10767600
Zhang Q et al. Studies on the cyclosporin A loaded stearic acid nanoparticles. 2000 Int J Pharm pmid:10867245
Ehinger AM and Kietzmann M Tissue distribution of oxacillin and ampicillin in the isolated perfused bovine udder. 2000 J Vet Med A Physiol Pathol Clin Med pmid:10842465
Stanley JC VAT and fat. Taxing single nutrient is dangerous. 2000 BMJ pmid:10877557
Robson H et al. An investigation into the release of cefuroxime axetil from taste-masked stearic acid microspheres. III. The use of DSC and HSDSC as means of characterising the interaction of the microspheres with buffered media. 2000 Int J Pharm pmid:10878327
Richieri GV et al. Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. 2000 Biochemistry pmid:10852718