stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Wright LC et al. The origin of 1H NMR-visible triacylglycerol in human neutrophils. Highfatty acid environments result in preferential sequestration of palmitic acid into plasma membrane triacylglycerol. 2000 Eur. J. Biochem. pmid:10601852
Rukkwamsuk T et al. Interrelation of fatty acid composition in adipose tissue, serum, and liver of dairy cows during the development of fatty liver postpartum. 2000 J. Dairy Sci. pmid:10659963
Schwarzmann G et al. Using biotinylated gangliosides to study their distribution and traffic in cells by immunoelectron microscopy. 2000 Meth. Enzymol. pmid:11070901
Messier AM and Bizzozero OA Conserved fatty acid composition of proteolipid protein during brain development and in myelin subfractions. 2000 Neurochem. Res. pmid:10823577
Bessesen DH et al. Trafficking of dietary oleic, linolenic, and stearic acids in fasted or fed lean rats. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10827016
Shiromani PK and Clair J Statistical comparison of high-shear versus low-shear granulation using a common formulation. 2000 Drug Dev Ind Pharm pmid:10738654
Florin-Christensen J et al. Phosphatidylcholine formation is the predominant lipid biosynthetic event in the hemoparasite Babesia bovis. 2000 Mol. Biochem. Parasitol. pmid:10743618
Sun Y et al. [The study of the microwave reaction of stearic acid and pentyl amine]. 2000 Guang Pu Xue Yu Guang Pu Fen Xi pmid:12945403
Schmider W et al. Transport of heptafluorostearate across model membranes. Membrane transport of long-chain fatty acid anions I. 2000 J. Lipid Res. pmid:10787438
Wissing S et al. An investigation into the use of stepwise isothermal high sensitivity DSC as a means of detecting drug-excipient incompatibility. 2000 Int J Pharm pmid:10802407
Min Y et al. Pregnancy reduces arachidonic and docosahexaenoic in plasma triacylglycerols of Korean women. 2000 Int J Vitam Nutr Res pmid:10804459
Ahrabi SF et al. Influence of neutron activation factors on matrix tablets for site specific delivery to the colon. 2000 Eur J Pharm Sci pmid:10767600
Swaminathan V and Kildsig DO The effect of particle morphology on the physical stability of pharmaceutical powder mixtures: the effect of surface roughness of the carrier on the stability of ordered mixtures. 2000 Drug Dev Ind Pharm pmid:10769777
Plötz BM et al. Characterization of a novel lipid A containing D-galacturonic acid that replaces phosphate residues. The structure of the lipid a of the lipopolysaccharide from the hyperthermophilic bacterium Aquifex pyrophilus. 2000 J. Biol. Chem. pmid:10753930
Daubresse JC [Atherosclerosis and nutrition]. 2000 Rev Med Brux pmid:11068494
Podczeck F and Newton JM Powder and capsule filling properties of lubricated granulated cellulose powder. 2000 Eur J Pharm Biopharm pmid:11072194
Engler MM et al. Dietary docosahexaenoic acid affects stearic acid desaturation in spontaneously hypertensive rats. 2000 Lipids pmid:11026622
Miersch O and Wasternack C Octadecanoid and jasmonate signaling in tomato (Lycopersicon esculentum Mill.) leaves: endogenous jasmonates do not induce jasmonate biosynthesis. 2000 Biol. Chem. pmid:11030429
Fitch CD et al. A role for linoleic acid in erythrocytes infected with Plasmodium berghei. 2000 Biochim. Biophys. Acta pmid:11113630
Knopp RH et al. One-year effects of increasingly fat-restricted, carbohydrate-enriched diets on lipoprotein levels in free-living subjects. 2000 Proc. Soc. Exp. Biol. Med. pmid:11082213
French SJ et al. The effects of intestinal infusion of long-chain fatty acids on food intake in humans. 2000 Gastroenterology pmid:11040181
Saito A et al. Effects of capsaicin on biliary free fatty acids in rats. 2000 Int J Vitam Nutr Res pmid:10683757
Granot E et al. Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. 2000 Am. J. Clin. Nutr. pmid:11063450
Willie BM et al. Possible explanation for the white band artifact seen in clinically retrieved polyethylene tibial components. 2000 J. Biomed. Mater. Res. pmid:11007625
Wardrop J et al. Determination of erythromycin and related substances in enteric-coated tablet formulations by reversed-phase liquid chromatography. 2000 J Pharm Sci pmid:10944374
Khalil MH et al. Topical application of docosanol- or stearic acid-containing creams reduces severity of phenol burn wounds in mice. 2000 Contact Derm. pmid:10945745
Broderick PA et al. Monoamine neurotransmitters in resected hippocampal subparcellations from neocortical and mesial temporal lobe epilepsy patients: in situ microvoltammetric studies. 2000 Brain Res. pmid:10996135
Mossab A et al. Utilization of soybean oil and tallow in young turkeys compared with young chickens. 2000 Poult. Sci. pmid:11020079
Enjalbert F et al. Effects of duodenal infusions of palmitic, stearic, or oleic acids on milk composition and physical properties of butter. 2000 J. Dairy Sci. pmid:10908048
Russo LI and Ghaly ES Drug release from Carbomer 934 matrices. 2000 P R Health Sci J pmid:10909708
Schweigert FJ and Bok V Vitamin A in blood plasma and urine of dogs is affected by the dietary level of vitamin A. 2000 Int J Vitam Nutr Res pmid:10883401
Zhang Q et al. Studies on the cyclosporin A loaded stearic acid nanoparticles. 2000 Int J Pharm pmid:10867245
Ehinger AM and Kietzmann M Tissue distribution of oxacillin and ampicillin in the isolated perfused bovine udder. 2000 J Vet Med A Physiol Pathol Clin Med pmid:10842465
Stanley JC VAT and fat. Taxing single nutrient is dangerous. 2000 BMJ pmid:10877557
Robson H et al. An investigation into the release of cefuroxime axetil from taste-masked stearic acid microspheres. III. The use of DSC and HSDSC as means of characterising the interaction of the microspheres with buffered media. 2000 Int J Pharm pmid:10878327
Richieri GV et al. Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. 2000 Biochemistry pmid:10852718
Lee WN et al. Loss of regulation of lipogenesis in the Zucker diabetic (ZDF) rat. 2000 Am. J. Physiol. Endocrinol. Metab. pmid:10913044
Siaan M et al. Influence of Avicel PH-301 on the compressibility of alpha-methyldopa and phenobarbitone in direct compression. 2000 Drug Dev Ind Pharm pmid:10914328
Chang RK and Hussain MA Consolidation behavior of an experimental, cross-linked polyalkyl ammonium polymer. 2000 Drug Dev Ind Pharm pmid:10697761
Pohl EE et al. Changes of intrinsic membrane potentials induced by flip-flop of long-chain fatty acids. 2000 Biochemistry pmid:10677234
Rey H et al. Development of matrix-based theophylline sustained-release microtablets. 2000 Drug Dev Ind Pharm pmid:10677806
Willie BM et al. Elemental and morphological identification of third-body particulate and calcium stearate inclusions in polyethylene components. 2000 J. Biomed. Mater. Res. pmid:10713559
Jenkins TC Feeding oleamide to lactating Jersey cows 1. Effects on lactation performance and milk fatty acid composition. 2000 J. Dairy Sci. pmid:10714869
Alonso A et al. Lipid chain dynamics in stratum corneum studied by spin label electron paramagnetic resonance. 2000 Chem. Phys. Lipids pmid:10669304
Otz M and Thoma H Effects of the metal type and the roughness of the die wall on the expended work for tablet ejection. 2000 Pharm Dev Technol pmid:10669914
Sanders TA et al. Influence of fatty acid chain length and cis/trans isomerization on postprandial lipemia and factor VII in healthy subjects (postprandial lipids and factor VII). 2000 Atherosclerosis pmid:10729392
Weston WL and Morelli JG Steroid rosacea in prepubertal children. 2000 Arch Pediatr Adolesc Med pmid:10632252
Kaushik N and Vir S Variations in fatty acid composition of neem seeds collected from the Rajasthan state of India. 2000 Biochem. Soc. Trans. pmid:11171243
Parveez GK et al. Transgenic oil palm: production and projection. 2000 Biochem. Soc. Trans. pmid:11171275
Leese GP et al. Effects of growth hormone treatment on red cell plasma membrane fatty acid constituents in hypopituitary adults. 2000 Scott Med J pmid:11130294
Khabbaz F and Albertsson AC Great advantages in using a natural rubber instead of a synthetic SBR in a pro-oxidant system for degradable LDPE. 2000 Biomacromolecules pmid:11710197
Liu Q et al. Genetic modification of cotton seed oil using inverted-repeat gene-silencing techniques. 2000 Biochem. Soc. Trans. pmid:11288706
Fatibello-Filho O and Vieira IC Construction and analytical application of a biosensor based on stearic acid-graphite powder modified with sweet potato tissue in organic solvents. 2000 Fresenius J Anal Chem pmid:11227501
Robles Valderrama E et al. [Application of gas chromatography in the identification of Enterobacter cloacae, Enterobacter aerogenes, and Enterobacter agglomerans]. 1999 Jan-Mar Rev. Latinoam. Microbiol. pmid:10932747
Chen Y et al. [Studies on chemical constituents of Forsythia suspensa (Thunb) Vahl]. 1999 Zhongguo Zhong Yao Za Zhi pmid:12205888
Bardi L et al. Saccharomyces cerevisiae cell fatty acid composition and release during fermentation without aeration and in absence of exogenous lipids. 1999 Int. J. Food Microbiol. pmid:10357281
Bretillon L et al. Effects of conjugated linoleic acid isomers on the hepatic microsomal desaturation activities in vitro. 1999 Lipids pmid:10574661
Dürig T et al. An investigation into the erosion behaviour of a high drug-load (85%) particulate system designed for an extended-release matrix tablet. Analysis of erosion kinetics in conjunction with variations in lubrication, porosity and compaction rate. 1999 J. Pharm. Pharmacol. pmid:10579678
Kikuchi K et al. Fatty acid composition of choline and ethanolamine glycerophospholipid subclasses in heart tissue of mammals and migratory and demersal fish. 1999 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:10582315
Connor WE Harbingers of coronary heart disease: dietary saturated fatty acids and cholesterol. Is chocolate benign because of its stearic acid content? 1999 Am. J. Clin. Nutr. pmid:10584037
Ceschel GC et al. Optimization of a tablet containing chlorthalidone. 1999 Drug Dev Ind Pharm pmid:10596354
Klein J et al. Fatty acid ethyl esters: a novel biologic marker for heavy in utero ethanol exposure: a case report. 1999 Ther Drug Monit pmid:10604826
González MS and Brenner RR Fatty acid delta9-desaturation in the Triatoma infestans fat body: response to food and trehalose administrations. 1999 Lipids pmid:10606043
Kumar VB et al. Changes in membrane fatty acids and delta-9 desaturase in senescence accelerated (SAMP8) mouse hippocampus with aging. 1999 Life Sci. pmid:10573183
Liu CY et al. Synthesis and analytical properties of a novel columnar metallomesogenic polymer. 1999 J Chromatogr A pmid:10588341
Levy R and Herzberg GR Hydrolysis of long-chain, n-3 fatty acid enriched chylomicrons by cardiac lipoprotein lipase. 1999 Can. J. Physiol. Pharmacol. pmid:10588486
Duan J et al. [Analysis of ethereal extracts from Odondotermes formosanus and fungus garden]. 1999 Zhong Yao Cai pmid:12571918
Zhang Q et al. [Retention behavior of solutes on liquid chromatographic column packed with dynamically modified zirconia]. 1999 Se Pu pmid:12549113
Gu W et al. [Chemical composition of Fordia cauliflora Hemsl]. 1999 Zhongguo Zhong Yao Za Zhi pmid:12242814
Cavalli R et al. Solid lipid nanoparticles as carriers of hydrocortisone and progesterone complexes with beta-cyclodextrins. 1999 Int J Pharm pmid:10332075
Jones AE et al. Effect of fatty acid chain length and saturation on the gastrointestinal handling and metabolic disposal of dietary fatty acids in women. 1999 Br. J. Nutr. pmid:10341674
Kelly FD et al. Stearic acid-rich diets do not increase thrombotic risk factors in healthy males. 1999 Lipids pmid:10419148
Muszbek L et al. The pool of fatty acids covalently bound to platelet proteins by thioester linkages can be altered by exogenously supplied fatty acids. 1999 Lipids pmid:10419194
Crocker I et al. Significance of fatty acids in pregnancy-induced immunosuppression. 1999 Clin. Diagn. Lab. Immunol. pmid:10391868
Hidaka T et al. Screening of microbial products modifying the action of leptin (obese gene product) by a biosensor. 1999 J. Antibiot. pmid:10395281
Adachi T et al. A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation. 1999 J. Immunol. pmid:10395690
Alava MA et al. Fatty acid desaturation: effect of alphafetoprotein on alpha-linolenic acid conversion by fetal rat hepatocytes. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10359023
McKellop HA et al. Effect of molecular weight, calcium stearate, and sterilization methods on the wear of ultra high molecular weight polyethylene acetabular cups in a hip joint simulator. 1999 J. Orthop. Res. pmid:10376720
Neumann D et al. A comparison of sutures for adjustable strabismus surgery. 1999 J AAPOS pmid:10221801
Zuurman K et al. Effect of magnesium stearate on bonding and porosity expansion of tablets produced from materials with different consolidation properties. 1999 Int J Pharm pmid:10053207
Rukkwamsuk T et al. Hepatic fatty acid composition in periparturient dairy cows with fatty liver induced by intake of a high energy diet in the dry period. 1999 J. Dairy Sci. pmid:10068949
Jarvis GN et al. Isolation and characterization of two glycerol-fermenting clostridial strains from a pilot scale anaerobic digester treating high lipid-content slaughterhouse waste. 1999 J. Appl. Microbiol. pmid:10196746
Ebube NK et al. Application of near-infrared spectroscopy for nondestructive analysis of Avicel powders and tablets. 1999 Pharm Dev Technol pmid:10027209
Vargas CI and Ghaly ES Kinetic release of theophylline from hydrophilic swellable matrices. 1999 Drug Dev Ind Pharm pmid:10518245
Chajès V et al. Fatty-acid composition in serum phospholipids and risk of breast cancer: an incident case-control study in Sweden. 1999 Int. J. Cancer pmid:10521790
Xiao Y and Li X Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation. 1999 Brain Res. pmid:10536218
Mano T et al. Proton MR spectroscopy of Sjögren-Larsson's syndrome. 1999 AJNR Am J Neuroradiol pmid:10543638
Eliasen H et al. Growth mechanisms in melt agglomeration with a low viscosity binder. 1999 Int J Pharm pmid:10486433
Summers LK et al. Use of structured triacylglycerols containing predominantly stearic and oleic acids to probe early events in metabolic processing of dietary fat. 1999 J. Lipid Res. pmid:10508209
Facciotti MT et al. Improved stearate phenotype in transgenic canola expressing a modified acyl-acyl carrier protein thioesterase. 1999 Nat. Biotechnol. pmid:10385326
Eliasen H et al. Electrostatic charging during a melt agglomeration process. 1999 Int J Pharm pmid:10425354
Huang S et al. Interleukin-1 stimulates Jun N-terminal/stress-activated protein kinase by an arachidonate-dependent mechanism in mesangial cells. 1999 Kidney Int. pmid:10231436
Avdulov NA et al. Lipid binding to sterol carrier protein-2 is inhibited by ethanol. 1999 Biochim. Biophys. Acta pmid:9931423
Murakami K et al. Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. 1999 Biochem. Biophys. Res. Commun. pmid:10403814
Warnotte C et al. Unbound rather than total concentration and saturation rather than unsaturation determine the potency of fatty acids on insulin secretion. 1999 Mol. Cell. Endocrinol. pmid:10459862
Howes D et al. The fate of ingested glyceran esters of condensed castor oil fatty acids [polyglycerol polyricinoleate (PGPR)] in the rat. 1998 Sep-Oct Food Chem. Toxicol. pmid:9737418
Lee BJ et al. Preparation and characterization of melatonin-loaded stearyl alcohol microspheres. 1998 Nov-Dec J Microencapsul pmid:9818955
Merlo AO et al. Ribozymes targeted to stearoyl-ACP delta9 desaturase mRNA produce heritable increases of stearic acid in transgenic maize leaves. 1998 Plant Cell pmid:9761789
Fungwe TV et al. Fatty acids modulate lecithin:cholesterol acyltransferase secretion independently of effects on triglyceride secretion in primary rat hepatocytes. 1998 J. Nutr. pmid:9687543
Mikami T et al. Characterization of a O-fatty-acylated sulfatide from equine brain. 1998 Eur. J. Biochem. pmid:9692930