stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
NadtochiÄ­ VV and BrodskiÄ­ RA [Absorption routes of stearic acid and leucine in the small intestine of the rat after gamma irradiation]. 1983 Arkh Anat Gistol Embriol pmid:6639383
Hundrieser KE et al. Distribution of trans-octadecenoic acid in the major glycerolipids of human milk. 1983 J. Pediatr. Gastroenterol. Nutr. pmid:6644446
Hikal AH Dissolution of meprobamate from various tablet formulations. 1983 Pharmazie pmid:6669616
Kohn MC and Garfinkel D Computer simulation of metabolism in palmitate-perfused rat heart. I. Palmitate oxidation. 1983 Ann Biomed Eng pmid:6592996
Duncan MO et al. Treatment of chancroid with erythromycin. A clinical and microbiological appraisal. 1983 Br J Vener Dis pmid:6603249
Upreti GC et al. Membrane lipids of hepatic tissue. I. Neutral lipids from subcellular fractions of liver and hepatoma 7288CTC. 1983 J. Natl. Cancer Inst. pmid:6572743
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Flood MT et al. Vitamin A utilization in human retinal pigment epithelial cells in vitro. 1983 Invest. Ophthalmol. Vis. Sci. pmid:6885309
Chien JL and Hogan EL Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. 1983 J. Biol. Chem. pmid:6885798
Edwards EK and Edwards EK Allergic reaction to triethanolamine stearate in a sunscreen. 1983 Cutis pmid:6831931
Chapkin RS et al. Characterization of the individual phospholipids and their fatty acids in serum and high-density lipoprotein of the renal patient on long-term maintenance hemodialysis. 1983 J. Lab. Clin. Med. pmid:6833842
Hillmar I et al. Influence of fatty acids on microsomal diacylglycerol acyltransferase activity in primary cultures of hepatocytes. 1983 Hoppe-Seyler's Z. Physiol. Chem. pmid:6840704
Warrell DA et al. Pathophysiology and immunology of the Jarisch-Herxheimer-like reaction in louse-borne relapsing fever: comparison of tetracycline and slow-release penicillin. 1983 J. Infect. Dis. pmid:6842024
Zeisel SH et al. Formation of methylamines from ingested choline and lecithin. 1983 J. Pharmacol. Exp. Ther. pmid:6842395
Foot M et al. Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. 1983 Biochem. J. pmid:6847622
Quinn PA et al. Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. 1983 Am. J. Obstet. Gynecol. pmid:6849358
Streichman S et al. Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. 1983 Biochim. Biophys. Acta pmid:6849970
Sobel JD et al. Legionella bozemanii. Still another cause of pneumonia. 1983 JAMA pmid:6854903
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Khan KA et al. The effect of mixing time of magnesium stearate on the tableting properties of dried microcrystalline cellulose. 1983 Pharm Acta Helv pmid:6867042
Yoshida S et al. Brain free fatty acids, edema, and mortality in gerbils subjected to transient, bilateral ischemia, and effect of barbiturate anesthesia. 1983 J. Neurochem. pmid:6403669
Swendsen CL et al. 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine: a novel source of arachidonic acid in neutrophils stimulated by the calcium ionophore A23187. 1983 Biochem. Biophys. Res. Commun. pmid:6407484
Inman WH and Rawson NS Erythromycin estolate and jaundice. 1983 Br Med J (Clin Res Ed) pmid:6407653
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Gabriel SM and Simpkins JW Effects of a sustained-release naloxone pellet on luteinizing hormone secretion in female rats. 1983 Neuroendocrinology pmid:6139759
Hoover RL et al. Role of cholesterol in the capping of surface immunoglobulin receptors on murine lymphocytes. 1983 J. Cell Biol. pmid:6223042
Jacques NA Membrane perturbation by cerulenin modulates glucosyltransferase secretion and acetate uptake by Streptococcus salivarius. 1983 J. Gen. Microbiol. pmid:6229601
Agrawal HC et al. In vivo incorporation of [3H]palmitic acid into PO protein, the major intrinsic protein of rat sciatic nerve myelin. 1983 J. Biol. Chem. pmid:6189827
Oriel JD et al. Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. 1982 Oct-Dec Sex Transm Dis pmid:6821502
della Ventura A and della Ventura D [Clinical experiments with erythromycin stearate in surgery of the oral cavity]. 1982 May-Jun Odontostomatol Implantoprotesi pmid:6984149
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RÃ¥dberg T et al. Metabolic studies in gestational diabetic women during contraceptive treatment: effects on glucose tolerance and fatty acid composition of serum lipids. 1982 Gynecol. Obstet. Invest. pmid:7035304
Maddux MS et al. The effect of erythromycin on theophylline pharmacokinetics at steady state. 1982 Chest pmid:7042226
Aprahamian SA et al. Comparative studies on the kinetic parameters and product analyses of chicken and rat liver and yeast fatty acid synthetase. 1982 Comp. Biochem. Physiol., B pmid:7044669
Jacques NA Relationship between cyclopropane synthetase and the formation of cyclopropane fatty acids by Proteus vulgaris grown under various respiratory conditions. 1982 J. Gen. Microbiol. pmid:7045282
Wei TC Quantitative determination of chemical composition of gallstones by infrared absorption spectrophotometry. 1982 Taiwan Yi Xue Hui Za Zhi pmid:6954245
Slomiany BL et al. Lipid composition of the matrix of human submandibular salivary gland stones. 1982 Arch. Oral Biol. pmid:6958224
Goto M et al. Evidence for a correlation between swimming velocity and membrane fluidity of Tetrahymena cells. 1982 Biochim. Biophys. Acta pmid:6818990
Pharmaceutical Reimbursement Board; final maximum allowable cost (MAC) determinations for certain drug products--Health Care Financing Administration. Final notice. 1982 Fed Regist pmid:10259800
Rosing U et al. Relative fatty acid composition of serum lecithin in the second half of the normal pregnancy. 1982 Gynecol. Obstet. Invest. pmid:7129232
Heimdahl A and Nord CE Influence of erythromycin on the normal human flora and colonization of the oral cavity, throat and colon. 1982 Scand. J. Infect. Dis. pmid:7071527
Woodward H et al. Isolation, purification, and properties of respiratory mucus glycoproteins. 1982 Biochemistry pmid:7074033
Katz AM et al. Fatty acid effects on calcium influx and efflux in sarcoplasmic reticulum vesicles from rabbit skeletal muscle. 1982 Biochim. Biophys. Acta pmid:7074105
Bridges CD et al. Vitamin A in human eyes: amount, distribution, and composition. 1982 Invest. Ophthalmol. Vis. Sci. pmid:7076416
Lehmann J and McGill M Biochemical and ultrastructural alterations in platelets, reticulocytes, and lymphocytes from rats fed vitamin E-deficient diets. 1982 J. Lipid Res. pmid:7077144
Josefsson K et al. Dose-related pharmacokinetics after oral administration of a new formulation of erythromycin base. 1982 Br J Clin Pharmacol pmid:7082537
NadtochiÄ­ VV and BrodskiÄ­ RA [Absorption study of 3H-stearic acid in the rat small intestine using electron microscopic autoradiography]. 1982 Tsitologiia pmid:7135486
Chen SC et al. Calorimetric evidence for phase transitions in spin-label lipid bilayers. 1982 Biochemistry pmid:7138849