| MeSH term | MeSH ID | Detail |
|---|---|---|
| Insulinoma | D007340 | 28 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Liver Neoplasms | D008113 | 8 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Irvine RF et al. | The calcium-dependent phosphatidylinositol-phosphodiesterase of rat brain. Mechanisms of suppression and stimulation. | 1979 | Eur. J. Biochem. | pmid:227685 |
| Butzler JP et al. | Clinical and pharmacological evaluation of different preparations of oral erythromycin. | 1979 | Chemotherapy | pmid:316377 |
| Colmano G et al. | Activated silver coatings for surgical implants. | 1979 | Va Med | pmid:316624 |
| Welling PG et al. | Plasma levels following single and repeated doses of erythromycin estolate and erythromycin stearate. | 1979 | J Pharm Sci | pmid:423080 |
| Lerk CF et al. | Effect of microcrystalline cellulose on liquid penetration in and disintegration of directly compressed tablets. | 1979 | J Pharm Sci | pmid:423092 |
| Saarni H et al. | Erythromycin levels in serum during treatment with erythromycin stearate and base. | 1979 | Ann. Clin. Res. | pmid:397800 |
| Tierno MA and Brenner RR | [Biochemistry of the developmental cycle of Triatoma infestans (Vinchuca). 2. Biosynthesis of fatty acids]. | 1979 | Acta Physiol Lat Am | pmid:400672 |
| Riordan JR et al. | Plasma membrane lipids of human diploid fibroblasts from normal individuals and patients with cystic fibrosis. | 1979 | Biochim. Biophys. Acta | pmid:476136 |
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| Holub BJ and Piekarski J | The formation of phosphatidylinositol by acylation of 2-acyl-sn-glycero-3-phosphorylinositol in rat liver microsomes. | 1979 | Lipids | pmid:459717 |
| Berend N et al. | Plasma and saliva concentrations for a new formulation of erythromycin stearate. | 1979 | Curr Med Res Opin | pmid:467089 |
| Doran TA et al. | Amniotic fluid lecithin/sphingomyelin ratio, palmitic acid, palmitic acid/stearic acid ratio, total cortisol, creatinine, and percentage of lipid-positive cells in assessment of fetal maturity and fetal pulmonary maturity: a comparison. | 1979 | Am. J. Obstet. Gynecol. | pmid:433991 |
| Nielsen GD et al. | [Aspiration of talcum or powder containing zinc stearate by children]. | 1979 | Ugeskr. Laeg. | pmid:442270 |
| Dunlop EM et al. | Penicillin levels in blood and CSF achieved by treatment of syphilis. | 1979 | JAMA | pmid:374763 |
| Malmborg AS | Effect of food on absorption of erythromycin. A study of two derivatives, the stearate and the base. | 1979 | J. Antimicrob. Chemother. | pmid:500517 |
| Wosilait WD and Ryan MP | The effects of oleic acid, tolbutamide, and oxyphenbutazone on the binding of warfarin by human serum albumin. | 1979 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:504792 |
| Rutland J et al. | The influence of food on the bioavailability of new formulations of erythromycin stearate and base. | 1979 | Br J Clin Pharmacol | pmid:508509 |
| Yakatan GJ et al. | Single-dose fasting bioequivalence assessment of erythromycin stearate tablets in man. | 1979 | J Pharmacokinet Biopharm | pmid:512842 |
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| Russell NJ and Harwood JL | Changes in the acyl lipid composition of photosynthetic bacteria grown under photosynthetic and non-photosynthetic conditions. | 1979 | Biochem. J. | pmid:115463 |
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| Eccleston GM | The structure and stability of O/W emulsions stabilised by polyethylene glycol 1000 monostearate/fatty alcohols [proceedings]. | 1979 | J. Pharm. Pharmacol. | pmid:42725 |
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| Melander A | Influence of food on the bioavailability of drugs. | 1978 Sep-Oct | Clin Pharmacokinet | pmid:81118 |
| Shepherd J et al. | Effects of dietary polyunsaturated and saturated fat on the properties of high density lipoproteins and the metabolism of apolipoprotein A-I. | 1978 | J. Clin. Invest. | pmid:207739 |
| Hellgren L and Vincent J | Erythromycin stearate in acne vulgaris: its effect on the skin surface lipids and on the activity of purified pancreatic lipase. | 1978 | Dermatologica | pmid:145975 |
| Mäntylä R et al. | Bioavailability and effect of food on the gastrointestinal absorption of two erythromycin derivatives. | 1978 | Ann. Clin. Res. | pmid:367255 |
| Yang YT et al. | Dietary lipid metabolism in lactating dairy cows. | 1978 | J. Dairy Sci. | pmid:568635 |
| Iranloye TA and Parrott EL | Effects of compression force, particle size, and lubricants on dissolution rate. | 1978 | J Pharm Sci | pmid:641763 |
| Gray AP and Yamauchi TN | Steroid antifertility agents. Ionic complexes of basic derivatives for prolonged action. | 1978 | J. Med. Chem. | pmid:671469 |
| Welling PG et al. | Bioavailability of erythromycin stearate: influence of food and fluid volume. | 1978 | J Pharm Sci | pmid:660450 |
| Abramov LA et al. | Acute respiratory distress caused by erythromycin hypersensitivity. | 1978 | Arch. Intern. Med. | pmid:666483 |
| Stein Y et al. | Intralysosomal hydrolysis of cholesterol esters of varying fatty acid composition in cultured human skin fibroblasts. | 1978 | Biochim. Biophys. Acta | pmid:698242 |
| Schuler LA et al. | Effect of luteinizing hormone of the lipid composition of rat ovaries. | 1978 | J. Endocrinol. | pmid:702016 |
| Triggs EJ and Ashley JJ | Oral administration of erythromycin stearate: effect of dosage form on plasma levels. | 1978 | Med. J. Aust. | pmid:713930 |
| Springolo V | [Bioavailability of formulations containing erythromycin base or stearate in soft enteric gelatin capsules]. | 1978 | Boll Chim Farm | pmid:743360 |
| Ahmed M and Enever RP | The influence of magnesium stearate on physical properties and biological availability of sulphadiazine tablet formulations. | 1978 | Pharm Acta Helv | pmid:746045 |
| Patelski J et al. | Effect of substrate composition and concentration on aortic cholesterol ester hydrolase activity. | 1978 | Enzyme | pmid:25174 |
| Meakin BJ et al. | The implication of stearate mould release agents in the loss of benzalkonium chloride from ophthalmic solutions in polyethylene bottles [proceedings]. | 1978 | J. Pharm. Pharmacol. | pmid:32268 |
| Paavolainen M et al. | Penetration of erythromycin stearate into maxillary sinus mucosa and secretion in chronic maxillary sinusitis. | 1977 Sep-Oct | Acta Otolaryngol. | pmid:199040 |
| Patil GS and Cornwell DG | Surface phase separation and collapse of the stearate anion--alkaline earth cation complex. | 1977 | J. Lipid Res. | pmid:833501 |
| Vilim A et al. | A simple thin-layer chromatographic identification procedure for erythromycin base, stearate, estolate and ethylsuccinate. | 1977 | J. Chromatogr. | pmid:838805 |
| Roguinsky M and Serieys F | [Treatment of mastitis in dry cows: treatment of all cows vs treatment of infected cows only (author's transl)]. | 1977 | Ann. Rech. Vet. | pmid:606146 |
| Sun GY | Metabolism of arachidonate and stearate injected simultaneously into the mouse brain. | 1977 | Lipids | pmid:895416 |
| Murthy KS and Samyn JC | Effect of shear mixing on in vitro drug release of capsule formulations containing lubricants. | 1977 | J Pharm Sci | pmid:903855 |
| Yamashita T and Tsubura E | [Influence of meal on the plasma concentration of patients received repeated administration of OE-7, erythromycin stearate capsules (author's transl)]. | 1977 | Jpn J Antibiot | pmid:909141 |
| Galpin JR and Allen JC | The influence of micelle formation on lipoxygenase kinetics. | 1977 | Biochim. Biophys. Acta | pmid:409436 |
| Donaldson RP and Beevers H | Lipid composition of organelles from germinating castor bean endosperm. | 1977 | Plant Physiol. | pmid:16659829 |