stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Reperfusion Injury D015427 65 associated lipids
Liver Neoplasms D008113 8 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Fodorová M et al. Structural features of lipid A of Rickettsia typhi. 2011 Acta Virol. pmid:21434703
Ropero J et al. Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation. 2011 Appl Spectrosc pmid:21396195
Junk MJ et al. DEER in biological multispin-systems: a case study on the fatty acid binding to human serum albumin. 2011 J. Magn. Reson. pmid:21450500
Franch-Lage F et al. Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging. 2011 Int J Pharm pmid:21419207
Xu QC et al. Enhanced photocatalytic activity of C-N-codoped TiO2 films prepared via an organic-free approach. 2011 J. Hazard. Mater. pmid:21316842
Zhou QT et al. Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach. 2011 J Pharm Sci pmid:21455980
Wang S et al. Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. 2011 PLoS Pathog. pmid:21731492
Paczkowski S and Schütz S Post-mortem volatiles of vertebrate tissue. 2011 Appl. Microbiol. Biotechnol. pmid:21720824
Wahjudi PN et al. Turnover of nonessential fatty acids in cardiolipin from the rat heart. 2011 J. Lipid Res. pmid:21957203
Haghjou N et al. Sustained release intraocular drug delivery devices for treatment of uveitis. 2011 J Ophthalmic Vis Res pmid:22454753
Paul D et al. Proteome and membrane fatty acid analyses on Oligotropha carboxidovorans OM5 grown under chemolithoautotrophic and heterotrophic conditions. 2011 PLoS ONE pmid:21386900
Ash MM et al. Phytosterol stearate esters elicit similar responses on plasma lipids and cholesterol absorption but different responses on fecal neutral sterol excretion and hepatic free cholesterol in male Syrian hamsters. 2011 Nutr Res pmid:21840470
Potta SG et al. Preparation and characterization of ibuprofen solid lipid nanoparticles with enhanced solubility. 2011 J Microencapsul pmid:21171818
Mosca M et al. Effect of membrane composition on lipid oxidation in liposomes. 2011 Chem. Phys. Lipids pmid:21185813
de Lima-Salgado TM et al. Molecular mechanisms by which saturated fatty acids modulate TNF-α expression in mouse macrophage lineage. 2011 Cell Biochem. Biophys. pmid:20809180
James J et al. Two-dimensional surface properties of PEO-PPO-PEO triblock copolymer film at the air/water interface in the absence and presence of Tyr-Phe dipeptide, Val-Tyr-Val tripeptide, SDS and stearic acid. 2011 Colloids Surf B Biointerfaces pmid:20888193
Ely DR and Carvajal MT Determination of the scale of segregation of low dose tablets using hyperspectral imaging. 2011 Int J Pharm pmid:21601625
Zhang Y and Clapp A Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. 2011 Sensors (Basel) pmid:22247651
Neji SB et al. Esterification of fatty acid over Tunisian acid activated clay: kinetic study. 2011 J Oleo Sci pmid:21606617
Whitney TR et al. Redberry juniper as a roughage source in lamb feedlot rations: wool and carcass characteristics, meat fatty acid profiles, and sensory panel traits. 2011 Meat Sci. pmid:21570776
Jishnu V et al. Formulation and evaluation of cephalexin extended release matrix tablets using 3 factorial design. 2011 J Young Pharm pmid:22224031
Yalcin H et al. Effect of gamma-irradiation on some chemical characteristics and volatile content of linseed. 2011 J Med Food pmid:21548804
Dong Z et al. Preparation and in vitro, in vivo evaluations of norfloxacin-loaded solid lipid nanopartices for oral delivery. 2011 Drug Deliv pmid:21554156
Oosterveer MH et al. Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. 2011 Nutr Metab (Lond) pmid:22201701
Zhang Y et al. α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. 2011 Lipids Health Dis pmid:21592363
Ting TC et al. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. 2011 J. Biol. Chem. pmid:21596756
Man TY et al. Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21406612
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Chen M et al. [Study on the chemical constituents from Fructus Toosendan (III)]. 2011 Zhong Yao Cai pmid:22500422
Wu DJ et al. Metabonomics-based omics study and atherosclerosis. 2011 J Clin Bioinforma pmid:22040517
Walash MI et al. Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. 2011 Chem Cent J pmid:21996025
El-Enany NM et al. Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate. 2011 Chem Cent J pmid:21978386
D'Ambrosio DN et al. Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage. 2011 PLoS ONE pmid:21949825
Nurul Syazana MS et al. Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. 2011 BMC Complement Altern Med pmid:21943200
Tachibana H Green tea polyphenol sensing. 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:21422740
Raza A and Zia-Ul-Haq M Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms. 2011 Int J Anal Chem pmid:21760789
Abdulrahman SA and Basavaiah K Sensitive and selective spectrophotometric determination of gabapentin in capsules using two nitrophenols as chromogenic agents. 2011 Int J Anal Chem pmid:21760787
Zenita O and Basavaiah K Utility of N-bromosuccinimide for the titrimetric and spectrophotometric determination of famotidine in pharmaceutical formulations. 2011 Int J Anal Chem pmid:21760785
Almer G et al. Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. 2011 Int J Nanomedicine pmid:21753879
Brown JD et al. VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. 2011 PLoS ONE pmid:21750705
Fernandez C et al. Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. 2011 PLoS ONE pmid:21738729
Singhal A et al. Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability. 2011 Pharmacognosy Res pmid:21731393
Li FQ et al. A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets. 2011 Int J Nanomedicine pmid:21720502
Amaya KR et al. Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. 2011 J. Neurochem. pmid:21496023
Duangjit S et al. Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. 2011 J Drug Deliv pmid:21490750
Kumaravelrajan R et al. Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination. 2011 Lipids Health Dis pmid:21477386
Kordyukova LV et al. Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. 2011 Biochim. Biophys. Acta pmid:21420932
Wang L et al. Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. 2011 AIDS Res Ther pmid:21385339
Intorre F et al. Differential effect of cheese fatty acid composition on blood lipid profile and redox status in normolipidemic volunteers: a pilot study. 2011 Int J Food Sci Nutr pmid:21591986
Liu Y et al. Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. 2011 Rapid Commun. Mass Spectrom. pmid:22006384
Fabiano A et al. Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results. 2011 J. Matern. Fetal. Neonatal. Med. pmid:21781003
Gresback R et al. Combined plasma gas-phase synthesis and colloidal processing of InP/ZnS core/shell nanocrystals. 2011 Nanoscale Res Lett pmid:21711589
Desai D et al. Fatty acid and water-soluble polymer-based controlled release drug delivery system. 2011 J Pharm Sci pmid:21374622
Watanabe H et al. Biosynthetic Pathway for Sex Pheromone Components Produced in a Plusiinae Moth, Plusia festucae. 2011 Front Endocrinol (Lausanne) pmid:22649385
Yee JK et al. Organ-specific alterations in fatty acid de novo synthesis and desaturation in a rat model of programmed obesity. 2011 Lipids Health Dis pmid:21569358
Shivanand K et al. In vivo bioavailability studies of sumatriptan succinate buccal tablets. 2011 Daru pmid:22615661
Gande S and Rao Y Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. 2011 Daru pmid:22615658
Varshosaz J et al. Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats. 2011 Daru pmid:22615647
Dey S et al. Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. 2011 ISRN Pharm pmid:22389855
Prajapati ST et al. Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. 2011 ISRN Pharm pmid:22389845
Flowers MT et al. Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. 2011 PLoS ONE pmid:21573029
Kulinowski P et al. Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. 2011 Pharm. Res. pmid:21181545
Christian F et al. Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. 2011 J. Biol. Chem. pmid:21177871
Mantzaris MD et al. Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells. 2011 FEBS J. pmid:21182590
Kouskoumvekaki I and Panagiotou G Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. 2011 J. Biomed. Biotechnol. pmid:20936122
Wang GG et al. Self-assembled biomimetic superhydrophobic CaCO3 coating inspired from fouling mineralization in geothermal water. 2011 Langmuir pmid:21919516
Basu BJ and Manasa J Effect of deposition parameters on the wettability and microstructure of superhydrophobic films with hierarchical micro-nano structures. 2011 J Colloid Interface Sci pmid:21864844
Su Z et al. Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine. 2011 Mol. Pharm. pmid:21770405
Asahi H et al. Plasmodium falciparum: differing effects of non-esterified fatty acids and phospholipids on intraerythrocytic growth in serum-free medium. 2011 Exp. Parasitol. pmid:21095186
Petelska AD and Figaszewski ZA The equilibria of phosphatidylcholine-fatty acid and phosphatidylcholine-amine in monolayers at the air/water interface. 2011 Colloids Surf B Biointerfaces pmid:20888195
MacDonald AM et al. A modified supported bilayer/diblock polymer--working towards a tunable coating for capillary electrophoresis. 2011 J Chromatogr A pmid:21122870
Liu X et al. Synthesis of high quality and stability CdS quantum dots with overlapped nucleation-growth process in large scale. 2011 J Colloid Interface Sci pmid:21040929
Tamilvanan S et al. In vitro and in vivo evaluation of hydrophilic and hydrophobic polymers-based nicorandil-loaded peroral tablet compared with its once-daily commercial sustained-release tablet. 2011 Drug Dev Ind Pharm pmid:20923389
Laus MN et al. Activation of the plant mitochondrial potassium channel by free fatty acids and acyl-CoA esters: a possible defence mechanism in the response to hyperosmotic stress. 2011 J. Exp. Bot. pmid:20801915
Li Y et al. Building layer-by-layer 3D supramolecular nanostructures at the terephthalic acid/stearic acid interface. 2011 Chem. Commun. (Camb.) pmid:21755081
Kumar A et al. Phytochemical investigation and antifeedant activity of Premna latifolia leaves. 2011 Nat. Prod. Res. pmid:21756197
Hirose A et al. Clofibric acid increases the formation of oleic acid in endoplasmic reticulum of the liver of rats. 2011 J. Pharmacol. Sci. pmid:21757842
Choi SE et al. Capsaicin attenuates palmitate-induced expression of macrophage inflammatory protein 1 and interleukin 8 by increasing palmitate oxidation and reducing c-Jun activation in THP-1 (human acute monocytic leukemia cell) cells. 2011 Nutr Res pmid:21745629
Fameau AL et al. Smart foams: switching reversibly between ultrastable and unstable foams. 2011 Angew. Chem. Int. Ed. Engl. pmid:21780260
Gremos S et al. Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. 2011 Bioresour. Technol. pmid:20888759
Li S et al. Preparation, characterization, pharmacokinetics and tissue distribution of solid lipid nanoparticles loaded with tetrandrine. 2011 AAPS PharmSciTech pmid:21811889
Klein CM and Jenkins TC Docosahexaenoic acid elevates trans-18:1 isomers but is not directly converted into trans-18:1 isomers in ruminal batch cultures. 2011 J. Dairy Sci. pmid:21854940
Waters LJ et al. Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. 2011 AAPS PharmSciTech pmid:21842309
Corvis Y et al. Physicochemical stability of solid dispersions of enantiomeric or racemic ibuprofen in stearic acid. 2011 J Pharm Sci pmid:21905027
Gao Q et al. Synthesis and characterization of novel amphiphilic copolymer stearic acid-coupled F127 nanoparticles for nano-technology based drug delivery system. 2011 Colloids Surf B Biointerfaces pmid:21906917
Varshosaz J et al. Lipid nanocapsule-based gels for enhancement of transdermal delivery of ketorolac tromethamine. 2011 J Drug Deliv pmid:22175029
Taylor M and Elhissi AM Predicting the physical properties of tablets from ATR-FTIR spectra using partial least squares regression. 2011 Pharm Dev Technol pmid:20100067
Perrault M et al. An experimental investigation of the effect of the amount of lubricant on tablet properties. 2011 Drug Dev Ind Pharm pmid:20704461
Du YZ et al. Quaternary complexes composed of plasmid DNA/protamine/fish sperm DNA/stearic acid grafted chitosan oligosaccharide micelles for gene delivery. 2011 Int. J. Biol. Macromol. pmid:21035503
Peng Q et al. A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. 2011 Microb. Cell Fact. pmid:22067554
Yu WL et al. Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. 2011 Microb. Cell Fact. pmid:22047615
Sekharan TR et al. Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline. 2011 Indian J Pharm Sci pmid:22707833
Nagarsekar KS et al. Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract of leaves of vitex negundo linn. 2011 Indian J Pharm Sci pmid:22707827
Bazzini AA et al. Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. 2011 PLoS ONE pmid:22174812
Masareddy R et al. Development of Orodispersible Tizanidine HCl Tablets Using Spray Dried Coprocessed Exipient Bases. 2011 Indian J Pharm Sci pmid:22707822
Mercado FV et al. Phase diagram of mixed monolayers of stearic acid and dimyristoylphosphatidylcholine. Effect of the acid ionization. 2011 Chem. Phys. Lipids pmid:21635875
Abbasi M et al. siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice. 2011 Pharm. Res. pmid:21638135
Lan DM et al. A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. 2011 Int J Mol Sci pmid:21747717
Lee YJ and Jenkins TC Biohydrogenation of linolenic acid to stearic acid by the rumen microbial population yields multiple intermediate conjugated diene isomers. 2011 J. Nutr. pmid:21653571
Sloat BR et al. In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles. 2011 Int J Pharm pmid:21371545