stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Foreign Bodies D005547 5 associated lipids
Whooping Cough D014917 6 associated lipids
Bronchitis D001991 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Hypopituitarism D007018 7 associated lipids
Gonorrhea D006069 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
MAHADEVAN S et al. STUDIES ON METABOLISM OF VITAMIN A. 4. STUDIES ON THE MODE OF ABSORPTION OF VITAMIN A BY RAT INTESTINE IN VITRO. 1963 Biochem. J. pmid:14071527
CORRIN B ALUMINIUM PNEUMOCONIOSIS. I. IN VITRO COMPARISON OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND A GRANULAR ALUMINIUM POWDER. 1963 Br J Ind Med pmid:14072616
CORRIN B ALUMINIUM PNEUMOCONIOSIS. II. EFFECT ON THE RAT LUNG OF INTRATRACHEAL INJECTIONS OF STAMPED ALUMINIUM POWDERS CONTAINING DIFFERENT LUBRICATING AGENTS AND OF A GRANULAR ALUMINIUM POWDER. 1963 Br J Ind Med pmid:14072617
KUNUGI K STUDIES ON THE SYNTHESES OF SUCROSE FATTY ACID ESTERS. IV. VELOCITY OF ALCOHOLYSIS REACTION. 1963 Chem. Pharm. Bull. pmid:14075263
BONE GJ and PARENT G Stearic acid, an essential growth factor for Trypanosoma cruzi. 1963 J. Gen. Microbiol. pmid:13968755
BONSER GM et al. A further study of bladder implantation in the mouse as a means of detecting carcinogenic activity: use of crushed paraffin wax or stearic acid as the vehicle. 1963 Br. J. Cancer pmid:13968883
BAKER RW et al. Fatty-acid composition of brain lecithins in multiple sclerosis. 1963 Lancet pmid:13969172
HEALD PJ and BADMAN HG LIPID METABOLISM AND THE LAYING HEN. I. PLASMA-FREE FATTY ACIDS AND THE ONSET OF LAYING IN THE DOMESTIC FOWL. 1963 Biochim. Biophys. Acta pmid:14067611
KERR SE and READ WW THE FATTY ACID COMPONENTS OF POLYPHOSPHOINOSITIDE PREPARED FROM CALF BRAIN. 1963 Biochim. Biophys. Acta pmid:14067624
ERWIN J and BLOCH K POLYUNSATURATED FATTY ACIDS IN SOME PHOTOSYNTHETIC MICROORGANISMS. 1963 Biochem Z pmid:14087318