stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Boutonneuse Fever D001907 5 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Whooping Cough D014917 6 associated lipids
Bronchitis D001991 6 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
Gonorrhea D006069 7 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Rosenthal MD and Whitehurst MC Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. 1983 Biochim. Biophys. Acta pmid:6615875
Hwang CC and Danti AG Percutaneous absorption of flufenamic acid in rabbits: effect of dimethyl sulfoxide and various nonionic surface-active agents. 1983 J Pharm Sci pmid:6620136
Philip J and Daly RE Test for selection of erythromycin stearate bulk drug for tablet preparation. 1983 J Pharm Sci pmid:6620167
Shih JC and Ohsawa R Differential effect of cholesterol on two types of 5-hydroxytryptamine binding sites. 1983 Neurochem. Res. pmid:6621769
van Kamp HV et al. Improvement by super disintegrants of the properties of tablets containing lactose, prepared by wet granulation. 1983 Pharm Weekbl Sci pmid:6622211
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Kushi Y et al. Comparative study of acidic glycosphingolipids by field desorption and secondary ion mass spectrometry. 1983 J. Biochem. pmid:6671968
Green B et al. Qualitative and quantitative changes in milk fat during lactation in the tammar wallaby (Macropus eugenii). 1983 Aust. J. Biol. Sci. pmid:6675645
Tulenko TN and Rabinowitz JL Metabolism of C14 mevalonate by adult and fetal arteries. 1983 Artery pmid:6677248
AkbuÄŸa J et al. Studies on flufenamic acid capsules and tablets. 1983 Pharmazie pmid:6634915
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Chien JL and Hogan EL Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. 1983 J. Biol. Chem. pmid:6885798
Pethick DW et al. The metabolism of circulating non-esterified fatty acids by the whole animal, hind-limb muscle and uterus of pregnant ewes. 1983 Br. J. Nutr. pmid:6821682
Slomiany A et al. Isolation of fatty acids covalently bound to the gastric mucus glycoprotein of normal and cystic fibrosis patients. 1983 Biochem. Biophys. Res. Commun. pmid:6860340
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Khan KA et al. The effect of mixing time of magnesium stearate on the tableting properties of dried microcrystalline cellulose. 1983 Pharm Acta Helv pmid:6867042
Shanson DC et al. High dose oral erythromycin for preventing endocarditis. 1983 Lancet pmid:6130318
de Haan P and Kalsbeek GL Humoral immune response to some benzylpenicillin preparations. 1983 Allergy pmid:6412583
Anderton P et al. Measles-virus-persistent infection in BGM cells. Modification of the incorporation of [3H]arachidonic acid and [14C]stearic acid into lipids. 1983 Biochem. J. pmid:6414459
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Bascoul J et al. Preparation of autoxidized cholesterol mixtures from [4-14C] cholesterol and cholesteryl fatty acid esters. 1983 J. Steroid Biochem. pmid:6423895
Kemp P and Lander DJ The hydrogenation of gamma-linolenic acid by pure cultures of two rumen bacteria. 1983 Biochem. J. pmid:6318740
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Carli F and Colombo I Influence of porosity on the contact angle of non-wet solids. 1983 J. Pharm. Pharmacol. pmid:6135790
Gabriel SM and Simpkins JW Effects of a sustained-release naloxone pellet on luteinizing hormone secretion in female rats. 1983 Neuroendocrinology pmid:6139759
Bleeker J Tolerance and efficacy of erythromycin stearate tablets versus enteric-coated erythromycin base capsules in the treatment of patients with acne vulgaris. 1983 J. Int. Med. Res. pmid:6219902
Hoover RL et al. Role of cholesterol in the capping of surface immunoglobulin receptors on murine lymphocytes. 1983 J. Cell Biol. pmid:6223042
Agrawal HC et al. In vivo incorporation of [3H]palmitic acid into PO protein, the major intrinsic protein of rat sciatic nerve myelin. 1983 J. Biol. Chem. pmid:6189827
Neufeld EJ et al. High affinity esterification of eicosanoid precursor fatty acids by platelets. 1983 J. Clin. Invest. pmid:6308046
Oriel JD et al. Treatment of gonococcal urethritis in men with a rifampicin-erythromycin combination. 1982 Oct-Dec Sex Transm Dis pmid:6821502
della Ventura A and della Ventura D [Clinical experiments with erythromycin stearate in surgery of the oral cavity]. 1982 May-Jun Odontostomatol Implantoprotesi pmid:6984149
May DC et al. The effects of erythromycin on theophylline elimination in normal males. 1982 Feb-Mar J Clin Pharmacol pmid:7068935
RÃ¥dberg T et al. Metabolic studies in gestational diabetic women during contraceptive treatment: effects on glucose tolerance and fatty acid composition of serum lipids. 1982 Gynecol. Obstet. Invest. pmid:7035304
Maddux MS et al. The effect of erythromycin on theophylline pharmacokinetics at steady state. 1982 Chest pmid:7042226
Eccleston GM The influence of fatty alcohols on the structure and stability of creams prepared with polyethylene glycol 1000 monostearate/fatty alcohols. 1982 Int J Cosmet Sci pmid:19469959
Pharmaceutical Reimbursement Board; final maximum allowable cost (MAC) determinations for certain drug products--Health Care Financing Administration. Final notice. 1982 Fed Regist pmid:10259800
Perkins RC et al. Equilibrium binding of spin-labeled fatty acids to bovine serum albumin: suitability as surrogate ligands for natural fatty acids. 1982 Biochemistry pmid:6289869
Akesson B Content of phospholipids in human diets studied by the duplicate-portion technique. 1982 Br. J. Nutr. pmid:7066286
Holub BJ The relative deacylation of different molecular species of endogenous phosphatidylethanolamine in rat liver microsomes by phospholipase activity. 1982 Biochim. Biophys. Acta pmid:7093298
Pritzker KP et al. Adrenal and hepatic calcium stearate crystal deposits in dogs fed a thiamine-deficient diet. 1982 Am. J. Vet. Res. pmid:7103233
Huang YS et al. Tissue lipids in acute acrylamide intoxicated rats. 1982 Can J Neurol Sci pmid:7104883
Townsend LE et al. In vitro acylation of rat brain myelin proteolipid protein. 1982 J. Biol. Chem. pmid:7107590
Sanchez J et al. Lipase-induced alterations of fatty acid synthesis by subcellular fractions from germinating pea (Pisum sativum L.). 1982 Biochem. J. pmid:7115342
Boyd RD et al. Oxidation rates of major fatty acids in fasting neonatal pigs. 1982 J. Anim. Sci. pmid:7118744
Rosing U et al. Relative fatty acid composition of serum lecithin in the second half of the normal pregnancy. 1982 Gynecol. Obstet. Invest. pmid:7129232
Heimdahl A and Nord CE Influence of erythromycin on the normal human flora and colonization of the oral cavity, throat and colon. 1982 Scand. J. Infect. Dis. pmid:7071527
Woodward H et al. Isolation, purification, and properties of respiratory mucus glycoproteins. 1982 Biochemistry pmid:7074033
Faas FH and Carter WJ Fatty acid desaturation and microsomal lipid fatty acid composition in experimental hypothyroidism. 1982 Biochem. J. pmid:7181859
Nozawa CM and Apostolov K Increase in the saturation of C18 fatty acids induced by coxsackie B6 virus in Vero cells. 1982 Virology pmid:6285601