stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Boutonneuse Fever D001907 5 associated lipids
Bronchitis D001991 6 associated lipids
Whooping Cough D014917 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Cholestasis, Extrahepatic D001651 7 associated lipids
Skin Diseases, Infectious D012874 7 associated lipids
Hypopituitarism D007018 7 associated lipids
Gonorrhea D006069 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Olivieri C et al. Phylogenetic position of a copper age sheep (Ovis aries) mitochondrial DNA. 2012 PLoS ONE pmid:22457789
Kottala N et al. Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. 2012 AAPS PharmSciTech pmid:22965660
Singh AV and Nath LK Evaluation of acetylated moth bean starch as a carrier for controlled drug delivery. 2012 Int. J. Biol. Macromol. pmid:22210486
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Shuhendler AJ et al. Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry. 2012 J Control Release pmid:21939700
Tamokou Jde D et al. Antioxidant and antimicrobial activities of ethyl acetate extract, fractions and compounds from stem bark of Albizia adianthifolia (Mimosoideae). 2012 BMC Complement Altern Med pmid:22809287
Brown PN et al. Determination of major phenolic compounds in Echinacea spp. raw materials and finished products by high-performance liquid chromatography with ultraviolet detection: single-laboratory validation matrix extension. 2011 Sep-Oct J AOAC Int pmid:22165004
Tomuta I et al. High-Throughput NIR-Chemometric Method for Meloxicam Assay from Powder Blends for Tableting. 2011 Oct-Dec Sci Pharm pmid:22145112
Nanjwade BK et al. Functions of lipids for enhancement of oral bioavailability of poorly water-soluble drugs. 2011 Oct-Dec Sci Pharm pmid:22145101
Jelvehgari M et al. Formulation, characterization and in vitro evaluation of theophylline-loaded Eudragit RS 100 microspheres prepared by an emulsion-solvent diffusion/evaporation technique. 2011 Nov-Dec Pharm Dev Technol pmid:20722498
Qu WX et al. Analysis of fatty acids in A. szechenyianum Gay. by microwave-assisted extraction and gas chromatography-mass spectrometry. 2011 May-Jun Phytochem Anal pmid:20848395
Nath B et al. Preparation and in vitro dissolution profile of zidovudine loaded microspheres made of Eudragit RS 100, RL 100 and their combinations. 2011 May-Jun Acta Pol Pharm pmid:21648196
BozdaÄŸ-Pehlivan S et al. Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. 2011 May-Jun Acta Pol Pharm pmid:21648198
Malik K et al. Taste masked microspheres of ofloxacin: formulation and evaluation of orodispersible tablets. 2011 Jul-Sep Sci Pharm pmid:21886910
Zaid AN et al. Formulation and bioequivalence of two valsartan tablets after a single oral administration. 2011 Jan-Mar Sci Pharm pmid:21617777
Shah DA et al. Stability indicating LC-method for estimation of paracetamol and lornoxicam in combined dosage form. 2011 Jan-Mar Sci Pharm pmid:21617776
Fodorová M et al. Structural features of lipid A of Rickettsia typhi. 2011 Acta Virol. pmid:21434703
Ropero J et al. Near-infrared chemical imaging slope as a new method to study tablet compaction and tablet relaxation. 2011 Appl Spectrosc pmid:21396195
Junk MJ et al. DEER in biological multispin-systems: a case study on the fatty acid binding to human serum albumin. 2011 J. Magn. Reson. pmid:21450500
Franch-Lage F et al. Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging. 2011 Int J Pharm pmid:21419207
Xu QC et al. Enhanced photocatalytic activity of C-N-codoped TiO2 films prepared via an organic-free approach. 2011 J. Hazard. Mater. pmid:21316842
Zhou QT et al. Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach. 2011 J Pharm Sci pmid:21455980
Sheikh KA et al. Influence of hydration state and homologue composition of magnesium stearate on the physical chemical properties of liquid paraffin lipogels. 2011 Int J Pharm pmid:21457766
Severino P et al. Polymorphism, crystallinity and hydrophilic-lipophilic balance of stearic acid and stearic acid-capric/caprylic triglyceride matrices for production of stable nanoparticles. 2011 Colloids Surf B Biointerfaces pmid:21543196
Zhou QT et al. Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties. 2011 Int J Pharm pmid:21527321
Wang S et al. Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars. 2011 PLoS Pathog. pmid:21731492
Manzano E et al. Study of the GC-MS determination of the palmitic-stearic acid ratio for the characterisation of drying oil in painting: La Encarnación by Alonso Cano as a case study. 2011 Talanta pmid:21530791
Paczkowski S and Schütz S Post-mortem volatiles of vertebrate tissue. 2011 Appl. Microbiol. Biotechnol. pmid:21720824
Wahjudi PN et al. Turnover of nonessential fatty acids in cardiolipin from the rat heart. 2011 J. Lipid Res. pmid:21957203
Paul D et al. Proteome and membrane fatty acid analyses on Oligotropha carboxidovorans OM5 grown under chemolithoautotrophic and heterotrophic conditions. 2011 PLoS ONE pmid:21386900
Ash MM et al. Phytosterol stearate esters elicit similar responses on plasma lipids and cholesterol absorption but different responses on fecal neutral sterol excretion and hepatic free cholesterol in male Syrian hamsters. 2011 Nutr Res pmid:21840470
Broderick PA and Kolodny EH Biosensors for brain trauma and dual laser doppler flowmetry: enoxaparin simultaneously reduces stroke-induced dopamine and blood flow while enhancing serotonin and blood flow in motor neurons of brain, in vivo. 2011 Sensors (Basel) pmid:22346571
Rojas J and Kumar V Comparative evaluation of silicified microcrystalline cellulose II as a direct compression vehicle. 2011 Int J Pharm pmid:21708237
Ely DR and Carvajal MT Determination of the scale of segregation of low dose tablets using hyperspectral imaging. 2011 Int J Pharm pmid:21601625
Neji SB et al. Esterification of fatty acid over Tunisian acid activated clay: kinetic study. 2011 J Oleo Sci pmid:21606617
Whitney TR et al. Redberry juniper as a roughage source in lamb feedlot rations: wool and carcass characteristics, meat fatty acid profiles, and sensory panel traits. 2011 Meat Sci. pmid:21570776
Yalcin H et al. Effect of gamma-irradiation on some chemical characteristics and volatile content of linseed. 2011 J Med Food pmid:21548804
Dong Z et al. Preparation and in vitro, in vivo evaluations of norfloxacin-loaded solid lipid nanopartices for oral delivery. 2011 Drug Deliv pmid:21554156
Zhang Y et al. α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. 2011 Lipids Health Dis pmid:21592363
Ting TC et al. Increased lipogenesis and stearate accelerate vascular calcification in calcifying vascular cells. 2011 J. Biol. Chem. pmid:21596756
Man TY et al. Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21406612
Pingali K et al. Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions. 2011 Drug Dev Ind Pharm pmid:20942612
Arora G et al. Formulation and evaluation of controlled release matrix mucoadhesive tablets of domperidone using Salvia plebeian gum. 2011 J Adv Pharm Technol Res pmid:22171313
Sathiyaraj S et al. Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation. 2011 J Adv Pharm Technol Res pmid:22171312
Solanki SS and Dahima R Formulation and evaluation of aceclofenac mouth-dissolving tablet. 2011 J Adv Pharm Technol Res pmid:22171305
Negi JS et al. Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL. 2011 J Adv Pharm Technol Res pmid:22171304
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
El-Enany NM et al. Spectrofluorimetric determination of sertraline in dosage forms and human plasma through derivatization with 9-fluorenylmethyl chloroformate. 2011 Chem Cent J pmid:21978386
D'Ambrosio DN et al. Distinct populations of hepatic stellate cells in the mouse liver have different capacities for retinoid and lipid storage. 2011 PLoS ONE pmid:21949825
Yin AW and Huang SJ [Research on chemical constituents of xuefu zhuyu decoction]. 2011 Zhong Yao Cai pmid:22372145
Nurul Syazana MS et al. Antiproliferative effect of methanolic extraction of tualang honey on human keloid fibroblasts. 2011 BMC Complement Altern Med pmid:21943200
Rajpurohit H et al. Hordeum vulgare hull in the design of fast disintegrating tablets. 2011 J Young Pharm pmid:21897660
Patel D et al. Design of Controlled Release Non-erodible Polymeric Matrix Tablet Using Microwave Oven-assisted Sintering Technique. 2011 J Young Pharm pmid:21897655
Tachibana H Green tea polyphenol sensing. 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:21422740
Fernandez C et al. Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. 2011 PLoS ONE pmid:21738729
Singhal A et al. Colon-targeted quercetin delivery using natural polymer to enhance its bioavailability. 2011 Pharmacognosy Res pmid:21731393
Li FQ et al. A novel spray-dried nanoparticles-in-microparticles system for formulating scopolamine hydrobromide into orally disintegrating tablets. 2011 Int J Nanomedicine pmid:21720502
Eggerath J et al. EDX-Element Analysis of the In Vitro Effect of Fluoride Oral Hygiene Tablets on Artificial Caries Lesion Formation and Remineralization in Human Enamel. 2011 Open Dent J pmid:21687564
Jeon I et al. Evaluation of roll compaction as a preparation method for hydroxypropyl cellulose-based matrix tablets. 2011 J Pharm Bioallied Sci pmid:21687348
Duangjit S et al. Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. 2011 J Drug Deliv pmid:21490750
Lim J et al. Solution structures of the acyl carrier protein domain from the highly reducing type I iterative polyketide synthase CalE8. 2011 PLoS ONE pmid:21674045
Kumaravelrajan R et al. Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination. 2011 Lipids Health Dis pmid:21477386
Kordyukova LV et al. Linker and/or transmembrane regions of influenza A/Group-1, A/Group-2, and type B virus hemagglutinins are packed differently within trimers. 2011 Biochim. Biophys. Acta pmid:21420932
Wang L et al. Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. 2011 AIDS Res Ther pmid:21385339
Sahu SK et al. Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel. 2011 J Drug Target pmid:20367067
Salem H et al. Nanosized rods agglomerates as a new approach for formulation of a dry powder inhaler. 2011 Int J Nanomedicine pmid:21383856
Nicholls HT et al. Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue. 2011 Diabetes pmid:21378177
Meng Y et al. Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase. 2011 Biotechnol Biofuels pmid:21366905
Intorre F et al. Differential effect of cheese fatty acid composition on blood lipid profile and redox status in normolipidemic volunteers: a pilot study. 2011 Int J Food Sci Nutr pmid:21591986
Gresback R et al. Combined plasma gas-phase synthesis and colloidal processing of InP/ZnS core/shell nanocrystals. 2011 Nanoscale Res Lett pmid:21711589
Desai D et al. Fatty acid and water-soluble polymer-based controlled release drug delivery system. 2011 J Pharm Sci pmid:21374622
Kulinowski P et al. Magnetic resonance imaging and image analysis for assessment of HPMC matrix tablets structural evolution in USP Apparatus 4. 2011 Pharm. Res. pmid:21181545
Christian F et al. Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. 2011 J. Biol. Chem. pmid:21177871
Gallardo LA et al. Europium stearate additives delay oxidation of UHMWPE for orthopaedic applications: a pilot study. 2011 Clin. Orthop. Relat. Res. pmid:21153455
Mantzaris MD et al. Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells. 2011 FEBS J. pmid:21182590
Basu BJ and Manasa J Effect of deposition parameters on the wettability and microstructure of superhydrophobic films with hierarchical micro-nano structures. 2011 J Colloid Interface Sci pmid:21864844
Su Z et al. Effect of octreotide-polyethylene glycol(100) monostearate modification on the pharmacokinetics and cellular uptake of nanostructured lipid carrier loaded with hydroxycamptothecine. 2011 Mol. Pharm. pmid:21770405
Hayashi Y et al. Modeling of latent structure of indomethacin solid dispersion tablet using Bayesian networks. 2011 Drug Dev Ind Pharm pmid:21702729
Naumowicz M et al. Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine. 2011 Cell Biochem. Biophys. pmid:21340532
Hsouna AB et al. Chemical composition, cytotoxicity effect and antimicrobial activity of Ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat. 2011 Int. J. Food Microbiol. pmid:21601302
Petelska AD and Figaszewski ZA The equilibria of phosphatidylcholine-fatty acid and phosphatidylcholine-amine in monolayers at the air/water interface. 2011 Colloids Surf B Biointerfaces pmid:20888195
Laus MN et al. Activation of the plant mitochondrial potassium channel by free fatty acids and acyl-CoA esters: a possible defence mechanism in the response to hyperosmotic stress. 2011 J. Exp. Bot. pmid:20801915
Gremos S et al. Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. 2011 Bioresour. Technol. pmid:20888759
Li S et al. Preparation, characterization, pharmacokinetics and tissue distribution of solid lipid nanoparticles loaded with tetrandrine. 2011 AAPS PharmSciTech pmid:21811889
Klein CM and Jenkins TC Docosahexaenoic acid elevates trans-18:1 isomers but is not directly converted into trans-18:1 isomers in ruminal batch cultures. 2011 J. Dairy Sci. pmid:21854940
Waters LJ et al. Controlled microwave processing applied to the pharmaceutical formulation of ibuprofen. 2011 AAPS PharmSciTech pmid:21842309
Corvis Y et al. Physicochemical stability of solid dispersions of enantiomeric or racemic ibuprofen in stearic acid. 2011 J Pharm Sci pmid:21905027
Gao Q et al. Synthesis and characterization of novel amphiphilic copolymer stearic acid-coupled F127 nanoparticles for nano-technology based drug delivery system. 2011 Colloids Surf B Biointerfaces pmid:21906917
Khan FN and Dehghan MH Enhanced bioavailability of atorvastatin calcium from stabilized gastric resident formulation. 2011 AAPS PharmSciTech pmid:21879394
Tsai MJ et al. Oral apomorphine delivery from solid lipid nanoparticles with different monostearate emulsifiers: pharmacokinetic and behavioral evaluations. 2011 J Pharm Sci pmid:20740670
Varshosaz J et al. Lipid nanocapsule-based gels for enhancement of transdermal delivery of ketorolac tromethamine. 2011 J Drug Deliv pmid:22175029
Taylor M and Elhissi AM Predicting the physical properties of tablets from ATR-FTIR spectra using partial least squares regression. 2011 Pharm Dev Technol pmid:20100067
Du YZ et al. Quaternary complexes composed of plasmid DNA/protamine/fish sperm DNA/stearic acid grafted chitosan oligosaccharide micelles for gene delivery. 2011 Int. J. Biol. Macromol. pmid:21035503
Bhattacharjee A et al. Deposition of stearate-oleate rich seed fat in Mangifera indica is mediated by a FatA type acyl-ACP thioesterase. 2011 Phytochemistry pmid:21130480
Yuan H et al. Stearic acid-g-chitosan polymeric micelle for oral drug delivery: in vitro transport and in vivo absorption. 2011 Mol. Pharm. pmid:21138243
Krogmann A et al. Inflammatory response of human coronary artery endothelial cells to saturated long-chain fatty acids. 2011 Microvasc. Res. pmid:21112343
Nagarsekar KS et al. Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract of leaves of vitex negundo linn. 2011 Indian J Pharm Sci pmid:22707827
Bazzini AA et al. Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. 2011 PLoS ONE pmid:22174812
Masareddy R et al. Development of Orodispersible Tizanidine HCl Tablets Using Spray Dried Coprocessed Exipient Bases. 2011 Indian J Pharm Sci pmid:22707822
Göker M et al. Complete genome sequence of the thermophilic sulfur-reducer Desulfurobacterium thermolithotrophum type strain (BSA(T)) from a deep-sea hydrothermal vent. 2011 Stand Genomic Sci pmid:22675590