stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Calculi D002137 3 associated lipids
Cattle Diseases D002418 24 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Brain Ischemia D002545 89 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Chancroid D002602 4 associated lipids
Coronary Disease D003327 70 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Decalcification, Pathologic D003649 1 associated lipids
Dermatitis D003872 30 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Butcher AE and Jones TM Some physical characteristics of magnesium stearate. 1972 J. Pharm. Pharmacol. pmid:4144914
Conte U et al. The effect of magnesium stearate and polytetrafluoroethylene as lubricants in direct compression of acetylsalicylic acid. 1972 Farmaco Prat pmid:5049531
Lesslauer W and Blasie JK Direct determination of the structure of barium stearate multilayers by x-ray diffraction. 1972 Biophys. J. pmid:5057749
Price CJ and Rowe CE Stimulation of the production of unesterified fatty acids in nerve endings of guinea-pig brain in vitro by noradrenaline and 5-hydroxytryptamine. 1972 Biochem. J. pmid:5075269
Patil GS et al. Effect of ionization and cation selectivity on the expansion of stearic acid monolayers. 1972 J. Lipid Res. pmid:5075503
Zackler J et al. A mass screening program for the detection of gonorrhea. 1972 Am. J. Obstet. Gynecol. pmid:4623083
Wahle KW and Garton GA Desaturation of stearate by sheep tissue microsomal preparations. 1972 Biochem. J. pmid:4643297
Kannangara CG and Stumpf PK Fat Metabolism in Higher Plants: XLVII. The Effect of Nitrite and Other Anions on the Formation of Unsaturated Fatty Acids by Isolated Chloroplasts. 1972 Plant Physiol. pmid:16657990
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. 1973 Yakugaku Zasshi pmid:4797567
Ryan DC et al. Estolate and stearate forms of erythromycin in the treatment of acute beta haemolytic streptococcal pharyngitis. 1973 Med. J. Aust. pmid:4568626
Bond JM et al. The second international reference preparation of procaine benzylpenicillin in oil with aluminium monostearate. 1973 Bull. World Health Organ. pmid:4541152
Arya OP and Bosa CB In search of an ideal single-session penicillin schedule for the treatment of gonorrhoea in Uganda. 1973 Br J Vener Dis pmid:4748409
McLeay A and Cooke P Estolate and stearate forms of erythromycin in beta-haemolytic streptococcal pharyngitis. 1973 Med. J. Aust. pmid:4694278
Norwitz G and Gordon H Determination of lithium stearate in sebacate-based lubricants by atomic absorption. 1973 Talanta pmid:18961363
Caldwell HC Dissolution of lithium and magnesium from lithium carbonate capsules containing magnesium stearate. 1974 J Pharm Sci pmid:4830001
Beleslin DB et al. Hyperthermic effect of palmitate sodium, stearate sodium and oleate sodium injected into the cerebral ventricles of conscious cats. 1974 Neuropharmacology pmid:4840846
Kasuya M et al. Toxic effect of cadmium stearate on rat cerebellum in culture. 1974 Bull Environ Contam Toxicol pmid:4474041
Antimicrobial efficacy of erythromycin stearate. A report from the general Practitioner Research Group. 1974 Practitioner pmid:4591200
Asker AF et al. Investigation of some materials as dry binders for direct compression in tablet manufacture. Part 5: Effects of lubricants and flow conditions. 1975 Pharmazie pmid:169527
York P Application of powder failure testing equipment in assessing effect on glidants on flowability of cohesive pharmaceutical powders. 1975 J Pharm Sci pmid:1151687