stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Skin Diseases, Infectious D012874 7 associated lipids
Seizures D012640 87 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Rosacea D012393 13 associated lipids
Relapsing Fever D012061 3 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Prostatic Diseases D011469 4 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Pneumoconiosis D011009 3 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Palma S et al. Design of Peumus boldus tablets by direct compression using a novel dry plant extract. 2002 Int J Pharm pmid:11897423
Muzíková J [Effect of magnesium stearate on the tensile strength of tablets made with the binder Prosolv SMCC 90]. 2002 Ceska Slov Farm pmid:11910741
Long GT et al. Hard to swallow dry: kinetics and mechanism of the anhydrous thermal decomposition of acetylsalicylic acid. 2002 J Pharm Sci pmid:11920766
Yokoyama K et al. Computerized posturography with sway frequency analysis: application in occupational and environmental health. 2002 Ind Health pmid:11926510
Gravena C et al. Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans. 2002 J. Endocrinol. pmid:11927386
Kushibiki S et al. Effect of beta-lactoglobulin on plasma retinol and triglyceride concentrations, and fatty acid composition in calves. 2001 J. Dairy Res. pmid:11928954
Wanten GJ et al. Saturated triglycerides and fatty acids activate neutrophils depending on carbon chain-length. 2002 Eur. J. Clin. Invest. pmid:11952815
Sato M et al. [Clinical studies on OE-7 chiefly in the treatment of acute respiratory infections (author's transl)]. 1975 Jpn J Antibiot pmid:1195513
Yao Y et al. Regulation of triacylglycerol and phospholipid trafficking by fatty acids in newborn swine enterocytes. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11960778
Møller JK et al. Effect of nitrosylmyoglobin and saturated fatty acid anions on metmyoglobin-catalyzed oxidation of aqueous methyl linoleate emulsions. 2002 Biochim. Biophys. Acta pmid:11985897
Eromosele CO and Eromosele IC Fatty acid compositions of seed oils of Haematostaphis barteri and Ximenia americana. 2002 Bioresour. Technol. pmid:11991081
Ali J et al. Buccoadhesive erodible disk for treatment of oro-dental infections: design and characterisation. 2002 Int J Pharm pmid:11996813
Bolwell GP et al. The apoplastic oxidative burst in response to biotic stress in plants: a three-component system. 2002 J. Exp. Bot. pmid:11997382
Alhamami OM The effects of some physico-chemical factors and pharmaceutical excipients on the bioavailability of nitrofurantoin oily and aqueous suspensions in rats. 2002 Drug Dev Ind Pharm pmid:12026223
Dobbins RL et al. The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. 2002 Diabetes pmid:12031970
Kelly FD et al. Short-term diets enriched in stearic or palmitic acids do not alter plasma lipids, platelet aggregation or platelet activation status. 2002 Eur J Clin Nutr pmid:12032647
Hu PC and Chen BH Effects of riboflavin and fatty acid methyl esters on cholesterol oxidation during illumination. 2002 J. Agric. Food Chem. pmid:12033831
Cozzini P et al. Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 1. Models without explicit constrained water. 2002 J. Med. Chem. pmid:12036355
Ohta N and Hatta I Interaction among molecules in mixtures of ceramide/stearic acid, ceramide/cholesterol and ceramide/stearic acid/cholesterol. 2002 Chem. Phys. Lipids pmid:12047901
Singhal R et al. Immobilization of urease on poly(N-vinyl carbazole)/stearic acid Langmuir-Blodgett films for application to urea biosensor. 2002 Biosens Bioelectron pmid:12052355