stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Skin Diseases, Infectious D012874 7 associated lipids
Seizures D012640 87 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Rosacea D012393 13 associated lipids
Relapsing Fever D012061 3 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Prostatic Diseases D011469 4 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Pneumoconiosis D011009 3 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Kashefi K et al. Geoglobus ahangari gen. nov., sp. nov., a novel hyperthermophilic archaeon capable of oxidizing organic acids and growing autotrophically on hydrogen with Fe(III) serving as the sole electron acceptor. 2002 Int. J. Syst. Evol. Microbiol. pmid:12054231
Aveldano MI and Bazán NG Rapid production of diacylglycerols enriched in arachidonate and stearate during early brain ischemia. 1975 J. Neurochem. pmid:1206411
Williams RO et al. Investigation of excipient type and level on drug release from controlled release tablets containing HPMC. 2002 Pharm Dev Technol pmid:12066573
Liu Q et al. High-oleic and high-stearic cottonseed oils: nutritionally improved cooking oils developed using gene silencing. 2002 J Am Coll Nutr pmid:12071306
Schmidt LE and Dalhoff K Food-drug interactions. 2002 Drugs pmid:12093316
Liang X et al. Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species. 2002 J. Biol. Chem. pmid:12105219
Anwar F et al. Analytical characterization of Salicornia bigelovii seed oil cultivated in Pakistan. 2002 J. Agric. Food Chem. pmid:12105947
Sebti I et al. Edible bioactive fatty acid-cellulosic derivative composites used in food-packaging applications. 2002 J. Agric. Food Chem. pmid:12105960
Østdal H et al. Reaction between protein radicals and other biomolecules. 2002 Free Radic. Biol. Med. pmid:12106816
Cao X et al. Langmuir and Langmuir-Blodgett films of a novel tryptophan peptide lipid. 2002 Chem. Commun. (Camb.) pmid:12122989
Phadtare S et al. Improved performance of preordered fungal protease-stearic acid biocomposites: enhanced catalytic activity, reusability, and temporal stability. 2002 Jul-Aug Biotechnol. Prog. pmid:12153301
Liu Q et al. High-stearic and High-oleic cottonseed oils produced by hairpin RNA-mediated post-transcriptional gene silencing. 2002 Plant Physiol. pmid:12177486
Lin JT et al. Molecular species of acylglycerols incorporating radiolabeled fatty acids from castor (Ricinus communis L.) microsomal incubations. 2002 J. Agric. Food Chem. pmid:12188611
LaFontaine MA et al. 3-nitropropionic acid-induced changes in bilayer fluidity in synaptosomal membranes: implications for Huntington's disease. 2002 Neurochem. Res. pmid:12199156
Chen Y et al. [Studies on chemical constituents of Forsythia suspensa (Thunb) Vahl]. 1999 Zhongguo Zhong Yao Za Zhi pmid:12205888
Berzins A et al. Surface damage in machined ram-extruded and net-shape molded retrieved polyethylene tibial inserts of total knee replacements. 2002 J Bone Joint Surg Am pmid:12208909
Giesy JG et al. Effect of dose of calcium salts of conjugated linoleic acid (CLA) on percentage and fatty acid content of milk fat in midlactation holstein cows. 2002 J. Dairy Sci. pmid:12214995
Yim B et al. Sonolysis of surfactants in aqueous solutions: an accumulation of solute in the interfacial region of the cavitation bubbles. 2002 Ultrason Sonochem pmid:12219583
Pollet S et al. [Substrates and products of fatty acid elongation in mouse brain microsomes]. 1975 Biochimie pmid:1222143
Li C et al. Resistance of cultivated tomato to cell content-feeding herbivores is regulated by the octadecanoid-signaling pathway. 2002 Plant Physiol. pmid:12226528