stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Hypopituitarism D007018 7 associated lipids
Hypothalamic Diseases D007027 3 associated lipids
Hypothyroidism D007037 32 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Infertility D007246 3 associated lipids
Insulin Resistance D007333 99 associated lipids
Insulinoma D007340 28 associated lipids
Ischemia D007511 18 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Legionnaires' Disease D007877 4 associated lipids
Leprosy D007918 8 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Liver Neoplasms D008113 8 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Kumar RV and Sinha VR Tailoring of drug delivery of 5-fluorouracil to the colon via a mixed film coated unit system. 2011 Acta Pharm pmid:21945913
Jing F et al. Phylogenetic and experimental characterization of an acyl-ACP thioesterase family reveals significant diversity in enzymatic specificity and activity. 2011 BMC Biochem. pmid:21831316
Guntupalli R et al. Phage Langmuir monolayers and Langmuir-Blodgett films. 2011 Colloids Surf B Biointerfaces pmid:20843668
Saeed M et al. Assessment of diffuse transmission and reflection modes in near-infrared quantification, part 2: DIFFuse reflection information depth. 2011 J Pharm Sci pmid:20862671
Uchino T et al. Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane. 2011 J Toxicol Sci pmid:21297346
Shin S et al. Time-oriented experimental design method to optimize hydrophilic matrix formulations with gelation kinetics and drug release profiles. 2011 Int J Pharm pmid:21251963
Calegari VC et al. Inflammation of the hypothalamus leads to defective pancreatic islet function. 2011 J. Biol. Chem. pmid:21257748
Uchimoto T et al. A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area. 2011 Eur J Pharm Biopharm pmid:21284955
Wadher KJ et al. Formulation and evaluation of a sustained-release tablets of metformin hydrochloride using hydrophilic synthetic and hydrophobic natural polymers. 2011 Indian J Pharm Sci pmid:22303065
Du YZ et al. Receptor-mediated gene delivery by folic acid-modified stearic acid-grafted chitosan micelles. 2011 Int J Nanomedicine pmid:21845046
Sharma S et al. RP-HPLC Method for Simultaneous Estimation of Nitazoxanide and Ofloxacin in Tablets. 2011 Indian J Pharm Sci pmid:22131628
Lavigne JP et al. Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections. 2011 BMC Res Notes pmid:22126300
Steidl S et al. Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. 2011 PLoS ONE pmid:22102904
Guschina I et al. Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. 2011 Lipids pmid:20963507
Bailey JA et al. Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. 2011 PLoS ONE pmid:21799757
Protière M et al. Rational design of the gram-scale synthesis of nearly monodisperse semiconductor nanocrystals. 2011 Nanoscale Res Lett pmid:21791060
Rajendraprasad N et al. Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. 2011 Int J Anal Chem pmid:21785594
Bhope SG et al. Design and development of a stable polyherbal formulation based on the results of compatibility studies. 2011 Pharmacognosy Res pmid:21772756
Yang J et al. Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes. 2011 BMC Genomics pmid:21631939
Chabukswar A et al. Six sigma: process of understanding the control and capability of ranitidine hydrochloride tablet. 2011 J Young Pharm pmid:21607050
Lacaze C et al. The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. 2011 Malar. J. pmid:21605361
Houmard JA et al. Is there a metabolic program in the skeletal muscle of obese individuals? 2011 J Obes pmid:21603262
Mahdi ES et al. Effect of surfactant and surfactant blends on pseudoternary phase diagram behavior of newly synthesized palm kernel oil esters. 2011 Drug Des Devel Ther pmid:21792294
Wang Y et al. [Analysis of plasma metabonomics of mini-swines with qi deficiency and blood stasis syndrome due to chronic myocardial ischemia]. 2011 Zhong Xi Yi Jie He Xue Bao pmid:21288451
Islam A and Ehsan A Comparison of suture material and technique of closure of subcutaneous fat and skin in caesarean section. 2011 N Am J Med Sci pmid:22540072
Green CD and Olson LK Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21266672
González-Mira E et al. Potential use of nanostructured lipid carriers for topical delivery of flurbiprofen. 2011 J Pharm Sci pmid:20575052
Peter A et al. Relationships between hepatic stearoyl-CoA desaturase-1 activity and mRNA expression with liver fat content in humans. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21045174
Han L et al. Starch stearate as a novel encapsulation wall material and its effect on oil-water interfacial tension. 2011 J Control Release pmid:22195872
Dasu MR and Jialal I Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:20959532
Goto T et al. Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. 2011 Biochem. J. pmid:21605082
Mužíková J and Eimerová I A study of the compaction process and the properties of tablets made of a new co-processed starch excipient. 2011 Drug Dev Ind Pharm pmid:21469946
Yoshida MI et al. Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions. 2011 Drug Dev Ind Pharm pmid:21449701
Kushner J et al. Examining the impact of excipient material property variation on drug product quality attributes: a quality-by-design study for a roller compacted, immediate release tablet. 2011 J Pharm Sci pmid:21319161
de Sousa Neto D et al. Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I). 2011 Chem. Phys. Lipids pmid:21238439
Seow LJ et al. Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. 2011 J Ethnopharmacol pmid:21167271
Liu H et al. A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. 2011 Nanotechnology pmid:21169661
Aardema H et al. Oleic acid prevents detrimental effects of saturated fatty acids on bovine oocyte developmental competence. 2011 Biol. Reprod. pmid:21311036
Pingali K et al. Mixing order of glidant and lubricant--influence on powder and tablet properties. 2011 Int J Pharm pmid:21356286
Zaki Rizkalla CM et al. In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery. 2011 AAPS PharmSciTech pmid:21800216
Roblegg E et al. Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion. 2011 Eur J Pharm Biopharm pmid:21801834
Van Hoeck V et al. Elevated non-esterified fatty acid concentrations during bovine oocyte maturation compromise early embryo physiology. 2011 PLoS ONE pmid:21858021
de Morais e Silva FA et al. Rosacea fulminans in pregnancy with ocular perforation. 2011 J Dtsch Dermatol Ges pmid:21366860
Morinaga N et al. Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59. 2011 Enzyme Microb. Technol. pmid:22113022
Tuei VC et al. Effects of human serum albumin complexed with free fatty acids on cell viability and insulin secretion in the hamster pancreatic β-cell line HIT-T15. 2011 Life Sci. pmid:21396379
Lee DM et al. Oxidative stress and inflammation in renal patients and healthy subjects. 2011 PLoS ONE pmid:21829457
Das SC et al. Use of surface energy distributions by inverse gas chromatography to understand mechanofusion processing and functionality of lactose coated with magnesium stearate. 2011 Eur J Pharm Sci pmid:21621612
Laverroux S et al. Isomerization of vaccenic acid to cis and trans C18:1 isomers during biohydrogenation by rumen microbes. 2011 Lipids pmid:21706384
Someshwar K et al. Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride. 2011 Acta Pharm pmid:21684848
Pani NR et al. Compatibility studies of nateglinide with excipients in immediate release tablets. 2011 Acta Pharm pmid:21684850
Němcová-Fürstová V et al. Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction. 2011 Cell. Physiol. Biochem. pmid:21691070
Pereira MG et al. Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions. 2011 PLoS ONE pmid:21818313
Xu M et al. Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism. 2011 J. Biol. Chem. pmid:21697096
Chaturvedi K et al. Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. 2010 Oct-Dec Sci Pharm pmid:21179326
Terekhova EA et al. [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. 2010 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:20391761
Kristó K et al. Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin. 2010 Jul-Aug Pharm Dev Technol pmid:19772392
Badawy SI et al. Effect of spray-dried mannitol on the performance of microcrystalline cellulose-based wet granulated tablet formulation. 2010 Jul-Aug Pharm Dev Technol pmid:20088677
Kaur G et al. Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. 2010 Jan-Mar Sci Pharm pmid:21179370
Stanisz B et al. Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. 2010 Jan-Feb Acta Pol Pharm pmid:20210086
Aburahma MH et al. Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. 2010 Apr-Jun Sci Pharm pmid:21179352
Singh B et al. Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. 2010 Apr-Jun Sci Pharm pmid:21179349
Salem HF Sustained-release progesterone nanosuspension following intramuscular injection in ovariectomized rats. 2010 Int J Nanomedicine pmid:21187946
Rideout TC et al. Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice. 2010 Mol Nutr Food Res pmid:20333723
Zornetzer GA et al. The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond. 2010 Biochemistry pmid:20014832
Almeida CP et al. Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. 2010 Int J Nanomedicine pmid:20957219
Varshosaz J et al. Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. 2010 Int J Prev Med pmid:21566772
Zhou Q et al. Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating. 2010 J Pharm Sci pmid:19795479
Balch RJ and Trescot A Extended-release morphine sulfate in treatment of severe acute and chronic pain. 2010 J Pain Res pmid:21197323
Uchimoto T et al. Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate. 2010 Int J Pharm pmid:19913080
Nouri A et al. Effect of process control agent on the porous structure and mechanical properties of a biomedical Ti-Sn-Nb alloy produced by powder metallurgy. 2010 Acta Biomater pmid:19815096
El Hadrami A et al. Chitosan in plant protection. 2010 Mar Drugs pmid:20479963
A J et al. Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses. 2010 PLoS ONE pmid:20949032
Thörn K et al. Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells. 2010 Lipids Health Dis pmid:20920255
Aly S Detachment and recovery index: A new parameter measuring powder compressibility. 2010 J Adv Pharm Technol Res pmid:22247881
Brown AW et al. Plant sterol and stanol substrate specificity of pancreatic cholesterol esterase. 2010 J. Nutr. Biochem. pmid:19615880
Tripathi B and Platel K Finger millet (Eleucine coracana) flour as a vehicle for fortification with zinc. 2010 J Trace Elem Med Biol pmid:20122580
Pires de Souza FC et al. In vitro comparison of the radiopacity of cavity lining materials with human dental structures. 2010 J Conserv Dent pmid:20859477
Huang WH et al. Development of liposomal salbutamol sulfate dry powder inhaler formulation. 2010 Biol. Pharm. Bull. pmid:20190418
Jeong SH and Park K Simple preparation of coated resin complexes and their incorporation into fast-disintegrating tablets. 2010 Arch. Pharm. Res. pmid:20191352
Cho KH et al. Monoacylglycerol (MAG)-oleic acid has stronger antioxidant, anti-atherosclerotic, and protein glycation inhibitory activities than MAG-palmitic acid. 2010 J Med Food pmid:20136442
Yang X et al. In vitro skin permeation of hinokitiol loaded in vesicles composed of behenyltrimethylammonium chloride and stearic acid. 2010 Drug Dev Ind Pharm pmid:20141448
Ye M et al. Synthesis of Sb2E3 (E = S, Se) nanorods with a flat cross section by a rapid hot injection method. 2010 J Nanosci Nanotechnol pmid:21138031
Xu Y et al. Carbon-covered magnetic nanomaterials and their application for the thermolysis of cancer cells. 2010 Int J Nanomedicine pmid:20463932
Prossnigg F et al. Packing behaviour of two predominant anionic phospholipids of bacterial cytoplasmic membranes. 2010 Biophys. Chem. pmid:20451316
Chitapanarux I et al. Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. 2010 Radiat Oncol pmid:20444243
Croxton RS et al. Variation in amino acid and lipid composition of latent fingerprints. 2010 Forensic Sci. Int. pmid:20413233
Shi X et al. On the coating of precipitated calcium carbonate with stearic acid in aqueous medium. 2010 Langmuir pmid:20334413
Hsieh HT et al. Facile synthesis of silver nanoparticles in CO2-expanded liquids from silver isostearate precursor. 2010 Langmuir pmid:20297774
Xing Z et al. Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. 2010 Acta Biomater pmid:20226284
O'Byrne SM et al. Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20040693
Collins JM et al. De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. 2010 J. Biol. Chem. pmid:20032470
Salbu L et al. Direct compression behavior of low- and high-methoxylated pectins. 2010 AAPS PharmSciTech pmid:20013080
Kordyukova LV et al. Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. 2010 Virology pmid:20006369
Kushner J and Moore F Scale-up model describing the impact of lubrication on tablet tensile strength. 2010 Int J Pharm pmid:20667504
Imae R et al. Intracellular phospholipase A1 and acyltransferase, which are involved in Caenorhabditis elegans stem cell divisions, determine the sn-1 fatty acyl chain of phosphatidylinositol. 2010 Mol. Biol. Cell pmid:20668164
Su C et al. A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC. 2010 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:20732836
Yoo HJ and HÃ¥kansson K Determination of double bond location in fatty acids by manganese adduction and electron induced dissociation. 2010 Anal. Chem. pmid:20704384
Zhang Y et al. The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity. 2010 J. Lipid Res. pmid:19609006
Romanowicz L and Bańkowski E Altered sphingolipid composition in Wharton's jelly of pre-eclamptic newborns. 2010 Pathobiology pmid:20332667
Valencia-Chamorro SA et al. Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins. 2010 J. Food Sci. pmid:21535515