stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Fang X et al. Development and analysis of an in vivo-compatible metabolic network of Mycobacterium tuberculosis. 2010 BMC Syst Biol pmid:21092312
Rideout TC et al. Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice. 2010 Mol Nutr Food Res pmid:20333723
Zornetzer GA et al. The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond. 2010 Biochemistry pmid:20014832
Westerbacka J et al. Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. 2010 Gastroenterology pmid:20600015
Even P et al. Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. 2010 Metab. Clin. Exp. pmid:19775712
Hirabara SM et al. Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells. 2010 J. Cell. Physiol. pmid:19780047
Lehto T et al. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. 2010 J Control Release pmid:19744531
Tay T et al. Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism? 2010 Int J Pharm pmid:19748561
Shen J et al. Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: Improving in vivo ocular distribution. 2010 Int J Pharm pmid:20934499
Almeida CP et al. Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. 2010 Int J Nanomedicine pmid:20957219
Renaville B et al. Plasma and follicular fluid fatty acid profiles in dairy cows. 2010 Reprod. Domest. Anim. pmid:19055554
Ram HN et al. Formulation and evaluation of floating tablets of liquorice extract. 2010 Pharmacognosy Res pmid:21589757
Varshosaz J et al. Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. 2010 Int J Prev Med pmid:21566772
Alizadeh M et al. The effect of hypocaloric diet enriched in legumes with or without L-arginine and selenium on anthropometric measures in central obese women. 2010 J Res Med Sci pmid:21526106
Elbaz A et al. Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro. 2010 J. Cell. Mol. Med. pmid:19382912
Louis J et al. PAD4-dependent antibiosis contributes to the ssi2-conferred hyper-resistance to the green peach aphid. 2010 Mol. Plant Microbe Interact. pmid:20367470
Ospina-E JC et al. Development of combinations of chemically modified vegetable oils as pork backfat substitutes in sausages formulation. 2010 Meat Sci. pmid:20374815
Ye S et al. Polyunsaturated docosahexaenoic acid suppresses oxidative stress induced endothelial cell calcium influx by altering lipid composition in membrane caveolar rafts. 2010 Prostaglandins Leukot. Essent. Fatty Acids pmid:20206488
Rajab M et al. Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid. 2010 Pharmazie pmid:20225651
Araújo J et al. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. 2010 Int J Pharm pmid:20362042
Kiss H et al. Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). 2010 Stand Genomic Sci pmid:21304711
Bender K et al. Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. 2010 Reproduction pmid:20385782
Jain S et al. Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. 2010 J Young Pharm pmid:21264091
Naumova EA et al. Influence of individual saliva secretion on fluoride bioavailability. 2010 Open Dent J pmid:21221176
Patel BP et al. Formulation and evaluation of mouth dissolving tablets of cinnarizine. 2010 Indian J Pharm Sci pmid:21218071
Kotagale NR et al. Carbopol 934-Sodium Alginate-Gelatin Mucoadhesive Ondansetron Tablets for Buccal Delivery: Effect of pH Modifiers. 2010 Indian J Pharm Sci pmid:21218058
Swami G et al. Soyabean powder as a novel diluent in tablet formulation of simvastatin. 2010 Indian J Pharm Sci pmid:21218051
Balch RJ and Trescot A Extended-release morphine sulfate in treatment of severe acute and chronic pain. 2010 J Pain Res pmid:21197323
Sorek N et al. An S-acylation switch of conserved G domain cysteines is required for polarity signaling by ROP GTPases. 2010 Curr. Biol. pmid:20451389
Murate M et al. Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane. 2010 Biochemistry pmid:20433166
Zhou QT et al. Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach. 2010 Int J Pharm pmid:20435112
Cohn JS et al. Reduction in intestinal cholesterol absorption by various food components: mechanisms and implications. 2010 Atheroscler Suppl pmid:20439167
Pantusa M and Bartucci R Kinetics of stearic acid transfer between human serum albumin and sterically stabilized liposomes. 2010 Eur. Biophys. J. pmid:20306030
El Hadrami A et al. Chitosan in plant protection. 2010 Mar Drugs pmid:20479963
Mir VG et al. Application of crustacean chitin as a co-diluent in direct compression of tablets. 2010 AAPS PharmSciTech pmid:20238188
Teixeira AC et al. Phase behaviour of oleanolic acid, pure and mixed with stearic acid: Interactions and crystallinity. 2010 Chem. Phys. Lipids pmid:20599856
Borah BM et al. Surface-modification-directed controlled adsorption of serum albumin onto magnetite nanocuboids synthesized in a gel-diffusion technique. 2010 J Colloid Interface Sci pmid:20621808
Zhu SH et al. [Study on the chemical constituents of Dichrocephala integrifolia]. 2010 Zhong Yao Cai pmid:20518304
Manickam E et al. Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. 2010 Lipids Health Dis pmid:20525346
Remya K et al. Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets. 2010 J Young Pharm pmid:21042477
Sateesha S et al. Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. 2010 J Young Pharm pmid:21042476
Hurko O et al. Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. 2010 Int J Alzheimers Dis pmid:20981353
A J et al. Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses. 2010 PLoS ONE pmid:20949032
Thörn K et al. Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells. 2010 Lipids Health Dis pmid:20920255
Aly S Detachment and recovery index: A new parameter measuring powder compressibility. 2010 J Adv Pharm Technol Res pmid:22247881
Brown AW et al. Plant sterol and stanol substrate specificity of pancreatic cholesterol esterase. 2010 J. Nutr. Biochem. pmid:19615880
Pires de Souza FC et al. In vitro comparison of the radiopacity of cavity lining materials with human dental structures. 2010 J Conserv Dent pmid:20859477
Lyra A et al. Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes. 2010 BMC Gastroenterol pmid:20849659
Roblegg E et al. Development of lipophilic calcium stearate pellets using ibuprofen as model drug. 2010 Eur J Pharm Biopharm pmid:20080179
Pan PH et al. Stearic acid attenuates cholestasis-induced liver injury. 2010 Biochem. Biophys. Res. Commun. pmid:20036638
Zhou YY et al. Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin. 2010 Int J Pharm pmid:20420886
Eftaiha AF et al. Bioadhesive controlled metronidazole release matrix based on chitosan and xanthan gum. 2010 Mar Drugs pmid:20559494
Wu T et al. Study on superhydrophobic hybrids fabricated from multiwalled carbon nanotubes and stearic acid. 2010 J Colloid Interface Sci pmid:20427047
Normand-Lauzière F et al. Increased postprandial nonesterified fatty acid appearance and oxidation in type 2 diabetes is not fully established in offspring of diabetic subjects. 2010 PLoS ONE pmid:20532041
Do PT et al. The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. 2010 Plant Physiol. pmid:20841452
Rivera CA et al. Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. 2010 BMC Gastroenterol pmid:20509914
Tiemeyer S et al. Effect of surface charge distribution on the adsorption orientation of proteins to lipid monolayers. 2010 Langmuir pmid:20707324
Barupal DK et al. Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. 2010 BMC Biotechnol. pmid:20492649
Ye M et al. Synthesis of Sb2E3 (E = S, Se) nanorods with a flat cross section by a rapid hot injection method. 2010 J Nanosci Nanotechnol pmid:21138031
Xu Y et al. Carbon-covered magnetic nanomaterials and their application for the thermolysis of cancer cells. 2010 Int J Nanomedicine pmid:20463932
Harvey KA et al. Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. 2010 J. Lipid Res. pmid:20852092
Prossnigg F et al. Packing behaviour of two predominant anionic phospholipids of bacterial cytoplasmic membranes. 2010 Biophys. Chem. pmid:20451316
Chitapanarux I et al. Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. 2010 Radiat Oncol pmid:20444243
Howell AB et al. Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. 2010 BMC Infect. Dis. pmid:20398248
UÄŸurlu T et al. Effects of lubricants on binary direct compression mixtures. 2010 Drug Discov Ther pmid:22491169
Saravanakumari P and Mani K Structural characterization of a novel xylolipid biosurfactant from Lactococcus lactis and analysis of antibacterial activity against multi-drug resistant pathogens. 2010 Bioresour. Technol. pmid:20637606
Invernizzi G et al. Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements. 2010 Funct. Integr. Genomics pmid:20607344
Chon B et al. Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals. 2010 Phys Chem Chem Phys pmid:20607188
Lin SY et al. Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. 2010 Int J Pharm pmid:20561572
Bunn RC et al. Palmitate and insulin synergistically induce IL-6 expression in human monocytes. 2010 Cardiovasc Diabetol pmid:21054880
Asai T and Fujimoto Y Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. 2010 Phytochemistry pmid:20541780
Foster SP and Johnson CP Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. 2010 J. Insect Physiol. pmid:20540946
Thörn K and Bergsten P Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. 2010 J. Cell. Biochem. pmid:20524206
Zhou QT et al. Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders. 2010 Eur J Pharm Sci pmid:20433919
Nokhodchi A et al. Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives. 2010 Daru pmid:22615598
Croxton RS et al. Variation in amino acid and lipid composition of latent fingerprints. 2010 Forensic Sci. Int. pmid:20413233
Milanovic J et al. Microencapsulation of flavors in carnauba wax. 2010 Sensors (Basel) pmid:22315575
Shi X et al. On the coating of precipitated calcium carbonate with stearic acid in aqueous medium. 2010 Langmuir pmid:20334413
Nagaich U et al. Design and evaluation of a metronidazole central core matrix tablet. 2010 J Adv Pharm Technol Res pmid:22247836
Hsieh HT et al. Facile synthesis of silver nanoparticles in CO2-expanded liquids from silver isostearate precursor. 2010 Langmuir pmid:20297774
Bhattacharya S and Nagaich U Assessment of anti-nociceptive efficacy of costus speciosus rhizome in swiss albino mice. 2010 J Adv Pharm Technol Res pmid:22247830
Xing Z et al. Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. 2010 Acta Biomater pmid:20226284
Choi JN et al. Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. 2010 J. Agric. Food Chem. pmid:20225861
O'Byrne SM et al. Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20040693
Desando MA et al. Proton magnetic relaxation and the aggregation of n-octylammonium n-octadecanoate surfactant in deuterochloroform solution. 2010 J Colloid Interface Sci pmid:20223468
Collins JM et al. De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. 2010 J. Biol. Chem. pmid:20032470
Salbu L et al. Direct compression behavior of low- and high-methoxylated pectins. 2010 AAPS PharmSciTech pmid:20013080
Kordyukova LV et al. Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. 2010 Virology pmid:20006369
Jun HY et al. Long residence time of ultrasound microbubbles targeted to integrin in murine tumor model. 2010 Acad Radiol pmid:19815430
Lai TY et al. Alterations in serum fatty acid concentrations and desaturase activities in Bietti crystalline dystrophy unaffected by CYP4V2 genotypes. 2010 Invest. Ophthalmol. Vis. Sci. pmid:19797200
Gonzalez-Mira E et al. Design and ocular tolerance of flurbiprofen loaded ultrasound-engineered NLC. 2010 Colloids Surf B Biointerfaces pmid:20719479
Chakraborty S et al. Utilization of adsorption technique in the development of oral delivery system of lipid based nanoparticles. 2010 Colloids Surf B Biointerfaces pmid:20728320
Tripathi B et al. Fortification of sorghum (Sorghum vulgare) and pearl millet (Pennisetum glaucum) flour with zinc. 2010 J Trace Elem Med Biol pmid:20685098
Zhang Y et al. The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity. 2010 J. Lipid Res. pmid:19609006
Kuo WT et al. Polymeric micelles comprising stearic acid-grafted polyethyleneimine as nonviral gene carriers. 2010 J Nanosci Nanotechnol pmid:21133072
Li YW et al. [Studies on the chemical constituents of Ficus microcarpa]. 2010 Zhong Yao Cai pmid:21049616
Romanowicz L and Bańkowski E Altered sphingolipid composition in Wharton's jelly of pre-eclamptic newborns. 2010 Pathobiology pmid:20332667
Zhang L et al. Fabrication of nanotubules and microspheres from the self-assembly of amphiphilic monochain stearic acid derivatives. 2010 Langmuir pmid:21049915
Zarbakhsh A et al. Stabilization of alkylated azacrown ether by fatty acid at the air-water interface. 2010 Langmuir pmid:21049946
Thomas CP et al. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. 2010 J. Biol. Chem. pmid:20061396