stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Snoeren TA et al. Multidisciplinary approach to unravelling the relative contribution of different oxylipins in indirect defense of Arabidopsis thaliana. 2009 J. Chem. Ecol. pmid:19798534
Atherton HJ et al. Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse. 2009 Mol. Syst. Biol. pmid:19357638
Peters GH et al. Effects of fatty acid inclusion in a DMPC bilayer membrane. 2009 J Phys Chem B pmid:19195101
Sugisawa K et al. Rapid quantitative analysis of magnesium stearate in pharmaceutical powders and solid dosage forms by atomic absorption: method development and application in product manufacturing. 2009 J Pharm Biomed Anal pmid:19195812
Tuomasjukka SS et al. Regio-distribution of stearic acid is not conserved in chylomicrons after ingestion of randomised, stearic acid-rich fat in a single meal. 2009 J. Nutr. Biochem. pmid:19195862
Parlati C et al. Pulmonary spray dried powders of tobramycin containing sodium stearate to improve aerosolization efficiency. 2009 Pharm. Res. pmid:19184617
Matharu Z et al. Langmuir-Blodgett film based on MEH-PPV for cholesterol biosensor. 2009 Anal. Chim. Acta pmid:19185127
Kadotani A et al. Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19755671
Prajapati ST et al. Studies on formulation and in vitro evaluation of floating matrix tablets of domperidone. 2009 Indian J Pharm Sci pmid:20177450
Puzanowska-Tarasiewicz H et al. Spectroscopic and electrochemical analysis of psychotropic drugs. 2009 Indian J Pharm Sci pmid:20177449
Mahmoud AM et al. Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate. 2009 Int J Anal Chem pmid:20140080
Evans LM et al. Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice. 2009 Clin. Exp. Metastasis pmid:19267249
Mahmoud AM New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms. 2009 Int J Anal Chem pmid:20140076
Mukherjee S and Datta A Morphology and structural evolution in cobalt stearate Langmuir-Blodgett films. 2009 J Nanosci Nanotechnol pmid:19928206
Jayakumar OD et al. Water dispersible Fe3O4 nanoparticles carrying doxorubicin for cancer therapy. 2009 J Nanosci Nanotechnol pmid:19908532
Gängler P et al. In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel. 2009 BMC Oral Health pmid:19799785
Yonezawa T et al. Saturated fatty acids stimulate and insulin suppresses BMCP1 expression in bovine mammary epithelial cells. 2009 Biochem. Biophys. Res. Commun. pmid:19852928
Hellemans KH et al. Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase. 2009 PLoS ONE pmid:19787047
Masuoka HC et al. Mcl-1 degradation during hepatocyte lipoapoptosis. 2009 J. Biol. Chem. pmid:19734538
Yang Y et al. Radial-position-controlled doping of CdS/ZnS core/shell nanocrystals: surface effects and position-dependent properties. 2009 Chemistry pmid:19206119
Durak D and Kalender Y Fine structure and chemical analysis of the metathoracic scent gland secretion in Graphosoma lineatum (Linnaeus, 1758) (Heteroptera, Pentatomidae). 2009 C. R. Biol. pmid:19200924
Wu Y et al. Metabonomic profile of rats with acute liver rejection. 2009 OMICS pmid:19196102
Kaye RS et al. Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies. 2009 J Pharm Sci pmid:19189420
Sobal G et al. Uptake of 99mTc-labeled chondroitin sulfate by chondrocytes and cartilage: a promising agent for imaging of cartilage degeneration? 2009 Nucl. Med. Biol. pmid:19181270
Marvey BB Extrudate versus powder silica alumina as support for Re₂O₇ catalyst in the metathesis of seed oil-derivatives - a comparison. 2009 Int J Mol Sci pmid:19333442
Pérez-Berná AJ et al. Screening a peptide library by DSC and SAXD: comparison with the biological function of the parent proteins. 2009 PLoS ONE pmid:19194494
Figueiras AN et al. Epicuticular lipids induce aggregation in Chagas disease vectors. 2009 Parasit Vectors pmid:19173716
Qureshi J et al. Chronomodulated drug delivery system of salbutamol sulphate for the treatment of nocturnal asthma. 2008 May-Jun Indian J Pharm Sci pmid:20046744
Issa MM et al. Novel atomic absorption spectrometric and rapid spectrophotometric methods for the quantitation of paracetamol in saliva: application to pharmacokinetic studies. 2008 May-Jun Indian J Pharm Sci pmid:20046743
Gohel MC and Sarvaiya KG Exploration of cold extrusion for the preparation of enteric minitablets of isoniazid. 2008 May-Jun Indian J Pharm Sci pmid:20046736
Gohel MC et al. Modulation of venlafaxine hydrochloride release from press coated matrix tablet. 2008 May-Jun Indian J Pharm Sci pmid:20046735
Bhise SB and Aloorkar NH Formulation and in vitro Evaluation of Floating Capsules of Theophylline. 2008 Mar-Apr Indian J Pharm Sci pmid:20046717
Setty CM et al. Development of fast dispersible aceclofenac tablets: effect of functionality of superdisintegrants. 2008 Mar-Apr Indian J Pharm Sci pmid:20046709
Masareddy RS et al. Development of mouth dissolving tablets of clozapine using two different techniques. 2008 Jul-Aug Indian J Pharm Sci pmid:20046788
Syed AA and Syeda A Spectrophotometric determination of certain benzimidazole proton pump inhibitors. 2008 Jul-Aug Indian J Pharm Sci pmid:20046782
Baldania SL et al. RP-HPLC Estimation of Risperidone in Tablet Dosage Forms. 2008 Jul-Aug Indian J Pharm Sci pmid:20046778
Ganesh S et al. In vitro Evaluation of the Effect of Combination of Hydrophilic and Hydrophobic Polymers on Controlled Release Zidovudine Matrix Tablets. 2008 Jul-Aug Indian J Pharm Sci pmid:20046771
Cocchi M et al. [Membrane platelet fatty acids: biochemical characterisation of the ischemic cardiovascular disease, characteristics of the paediatric age, through an artificial neural network interpretation]. 2008 Jan-Feb Pediatr Med Chir pmid:18491675
Liang L and Fang Y Photoluminescence of a mixed Langmuir-Blodgett film of C(60) and stearic acid at room temperature. 2008 Spectrochim Acta A Mol Biomol Spectrosc pmid:17499018
Simon MN et al. Persistent activation of Akt or ERK prevents the toxicity induced by saturated and polyunsaturated fatty acids in RINm5F β-cells. 2008 Toxicol In Vitro pmid:18395405
Arida AI and Al-Tabakha MM Cellactose a co-processed excipient: a comparison study. 2008 Pharm Dev Technol pmid:18379907
Jones PJ Dietary agents that target gastrointestinal and hepatic handling of bile acids and cholesterol. 2008 J Clin Lipidol pmid:21291720
Lee YH et al. Separation and determination of polyethylene glycol fatty acid esters in cosmetics by a reversed-phase HPLC/ELSD. 2008 Talanta pmid:18371826
Darole PS et al. Formulation and evaluation of microemulsion based delivery system for amphotericin B. 2008 AAPS PharmSciTech pmid:18446472
Flasiński M et al. Per-6-O-(tert-butyldimethylsilyl)cyclodextrins (TBDMS-CDs) in Langmuir monolayers: the importance of a spreading solvent in the preparation of LB layers suitable for sensor application. 2008 J Phys Chem B pmid:18358030
Liao KS et al. Superhydrophobic surfaces formed using layer-by-layer self-assembly with aminated multiwall carbon nanotubes. 2008 Langmuir pmid:18324860
Hentschel A et al. Beta-carotene-loaded nanostructured lipid carriers. 2008 J. Food Sci. pmid:18298743
Georget DM et al. A study on maize proteins as a potential new tablet excipient. 2008 Eur J Pharm Biopharm pmid:18294824
Lee DY and Fiehn O High quality metabolomic data for Chlamydomonas reinhardtii. 2008 Plant Methods pmid:18442406
Xie L et al. Quality-by-design (QbD): effects of testing parameters and formulation variables on the segregation tendency of pharmaceutical powder measured by the ASTM D 6940-04 segregation tester. 2008 J Pharm Sci pmid:18271036
Gouda AA and Hassan WS Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations. 2008 Chem Cent J pmid:18410679
Lee WJ and Chen YC Novolak PF resins prepared from phenol liquefied Cryptomeria japonica and used in manufacturing moldings. 2008 Bioresour. Technol. pmid:18243689
Zaccone A et al. Correlation between colloidal stability and surfactant adsorption/association phenomena studied by light scattering. 2008 J Phys Chem B pmid:18229917
Tanka-Salamon A et al. Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids. Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation. 2008 FEBS J. pmid:18279394
Harding L et al. The development of microthermal analysis and photothermal microspectroscopy as novel approaches to drug-excipient compatibility studies. 2008 Int J Pharm pmid:18162342
Desai D et al. Solid-state interaction of stearic acid with povidone and its effect on dissolution stability of capsules. 2008 Int J Pharm pmid:18194844
Garay AS and Rodrigues DE Effects of the inclusion of the spin label 10-doxyl-stearic acid on the structure and dynamics of model bilayers in water: stearic acid and stearic acid/cholesterol (50:20). 2008 J Phys Chem B pmid:18198858
Bacher C et al. Granule fraction inhomogeneity of calcium carbonate/sorbitol in roller compacted granules. 2008 Int J Pharm pmid:17765416
Yuan H et al. Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. 2008 Int J Pharm pmid:17714896
Guchardi R et al. Influence of fine lactose and magnesium stearate on low dose dry powder inhaler formulations. 2008 Int J Pharm pmid:17689898
Wu H et al. Process analytical technology (PAT): quantification approaches in terahertz spectroscopy for pharmaceutical application. 2008 J Pharm Sci pmid:17722101
Hamad ML et al. Functionality of magnesium stearate derived from bovine and vegetable sources: dry granulated tablets. 2008 J Pharm Sci pmid:18351597
Guo J et al. Phenolic molding compound filled with nonmetals of waste PCBs. 2008 Environ. Sci. Technol. pmid:18284173
Nyblom HK et al. Glucose-induced de novo synthesis of fatty acyls causes proportional increases in INS-1E cellular lipids. 2008 NMR Biomed pmid:17691080
Werle M Natural and synthetic polymers as inhibitors of drug efflux pumps. 2008 Pharm. Res. pmid:17896100
Kauffman JF et al. Near infrared spectroscopy of magnesium stearate hydrates and multivariate calibration of pseudopolymorph composition. 2008 J Pharm Sci pmid:17546666
Houmadi S et al. Langmuir-Blodgett film of hydrophobin protein from Pleurotus ostreatus at the air-water interface. 2008 Langmuir pmid:18925762
Crowe FL et al. Fatty acid composition of plasma phospholipids and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition. 2008 Am. J. Clin. Nutr. pmid:18996872
Isaev NP and Dzuba SA Fast stochastic librations and slow rotations of spin labeled stearic acids in a model phospholipid bilayer at cryogenic temperatures. 2008 J Phys Chem B pmid:18826269
Koseki T et al. Development of novel fast-disintegrating tablets by direct compression using sucrose stearic acid ester as a disintegration-accelerating agent. 2008 Chem. Pharm. Bull. pmid:18827375
Navarro-Tarazaga ML et al. Fatty acid effect on hydroxypropyl methylcellulose-beeswax edible film properties and postharvest quality of coated 'Ortanique' mandarins. 2008 J. Agric. Food Chem. pmid:18950188
Fang YP et al. Physicochemical and safety evaluation of 5-aminolevulinic acid in novel liposomes as carrier for skin delivery. 2008 J Liposome Res pmid:18348070
Aoki PH et al. Sensor array made with nanostructured films to detect a phenothiazine compound. 2008 J Nanosci Nanotechnol pmid:19049023
Liu Q et al. Cobalt nanowires prepared by heterogeneous nucleation in propanediol and their catalytic properties. 2008 Nanotechnology pmid:21828879
Ishima Y et al. S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding. 2008 J. Biol. Chem. pmid:18940810
Lockridge JB et al. Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. 2008 J. Lipid Res. pmid:18387886
Xue R et al. A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18767022
Sadhu HG et al. Poisoning of workers working in small lead-based units. 2008 Indian J Occup Environ Med pmid:20040974
Kirtsreesakul V et al. Microbiology and antimicrobial susceptibility patterns of commensal flora in the middle nasal meatus. 2008 Ann. Otol. Rhinol. Laryngol. pmid:19140538
Chatterjee A and Chowdhury R Bile and unsaturated fatty acids inhibit the binding of cholera toxin and Escherichia coli heat-labile enterotoxin to GM1 receptor. 2008 Antimicrob. Agents Chemother. pmid:17954701
Karoussi O and Hamouda AA Macroscopic and nanoscale study of wettability alteration of oil-wet calcite surface in presence of magnesium and sulfate ions. 2008 J Colloid Interface Sci pmid:17931645
Fujio J et al. Regulation of gut-derived resistin-like molecule beta expression by nutrients. 2008 Diabetes Res. Clin. Pract. pmid:17936398
Richardson AD et al. Central carbon metabolism in the progression of mammary carcinoma. 2008 Breast Cancer Res. Treat. pmid:17879159
Smirnov AI Post-processing of EPR spectra by convolution filtering: calculation of a harmonics' series and automatic separation of fast-motion components from spin-label EPR spectra. 2008 J. Magn. Reson. pmid:17967556
Gotoh K et al. A quartz crystal microbalance simulation to examine the effect of ultraviolet light treatment on characteristics of polyethylene surface. 2008 J Oleo Sci pmid:18685232
Adeagbo AA and Alebiowu G Evaluation of cocoa butter as potential lubricant for coprocessing in pharmaceutical tablets. 2008 Pharm Dev Technol pmid:18484488
Cai JY et al. [Studies on chemical constituents from Anoectochilus roxburghii]. 2008 Zhong Yao Cai pmid:18619237
Ma BJ et al. [Chemical constituents study on the fruiting bodies of Lactarius rufus]. 2008 Zhong Yao Cai pmid:18619269
Fini A et al. Raman and thermal analysis of indomethacin/PVP solid dispersion enteric microparticles. 2008 Eur J Pharm Biopharm pmid:18621516
Liu LX et al. Effect of particle properties on the flowability of ibuprofen powders. 2008 Int J Pharm pmid:18652883
Lumor SE et al. Optimization of solid fat content and crystal properties of a trans-free structured lipid by blending with palm midfraction. 2008 J. Agric. Food Chem. pmid:18781758
Moon CD et al. Reclassification of Clostridium proteoclasticum as Butyrivibrio proteoclasticus comb. nov., a butyrate-producing ruminal bacterium. 2008 Int. J. Syst. Evol. Microbiol. pmid:18768601
Terés S et al. Oleic acid content is responsible for the reduction in blood pressure induced by olive oil. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18772370
Weber D et al. Quantification of lubricant activity of magnesium stearate by atomic force microscopy. 2008 Drug Dev Ind Pharm pmid:18777241
Simonsick WJ and Petkovska VI Detailed structural elucidation of polyesters and acrylates using Fourier transform mass spectrometry. 2008 Anal Bioanal Chem pmid:18719895
Aleong JM et al. Ice recrystallization inhibition in ice cream by propylene glycol monostearate. 2008 J. Food Sci. pmid:19021802
Johansson TP and Leach GW A low temperature phase transition in Langmuir-Blodgett films. 2008 J Phys Chem B pmid:18855435
Mazumder B et al. Flow of Formulation Granules through a Conical Hopper. 2008 Indian J Pharm Sci pmid:21369452
Shah DA et al. Stability Indicating RP-HPLC Estimation of Atorvastatin Calcium and Amlodipine Besylate in Pharmaceutical Formulations. 2008 Indian J Pharm Sci pmid:21369436
Zhang XX et al. Effects of breast cancer resistance protein inhibitors and pharmaceutical excipients on decreasing gastrointestinal toxicity of camptothecin analogs. 2008 Acta Pharmacol. Sin. pmid:18954535