| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Alves M and Peric M | An EPR study of the interfacial properties of phosphatidylcholine vesicles with different lipid chain lengths. | 2006 | Biophys. Chem. | pmid:16517048 |
| Ramirez-Dorronsoro JC et al. | Chargeability measurements of selected pharmaceutical dry powders to assess their electrostatic charge control capabilities. | 2006 | AAPS PharmSciTech | pmid:17285749 |
| Huber AH et al. | Fatty acid-specific fluorescent probes and their use in resolving mixtures of unbound free fatty acids in equilibrium with albumin. | 2006 | Biochemistry | pmid:17128966 |
| Douliez JP et al. | Self-assembly of fatty acid-alkylboladiamine salts. | 2006 | Langmuir | pmid:16401110 |
| Raith K et al. | Towards a molecular characterization of pharmaceutical excipients: mass spectrometric studies of ethoxylated surfactants. | 2006 | Int J Pharm | pmid:16730931 |
| Pérez-Vich B et al. | Molecular analysis of the high stearic acid content in sunflower mutant CAS-14. | 2006 | Theor. Appl. Genet. | pmid:16362273 |
| Urai M et al. | Structural analysis of an extracellular polysaccharide produced by Rhodococcus rhodochrous strain S-2. | 2006 | Carbohydr. Res. | pmid:16676419 |
| Shibata Y et al. | Fluidity and tableting characteristics of a powder solid dispersion of the low melting drugs ketoprofen and ibuprofen with crospovidone. | 2006 | Drug Dev Ind Pharm | pmid:16638683 |
| Capková P et al. | Structure of montmorillonite cointercalated with stearic acid and octadecylamine: modeling, diffraction, IR spectroscopy. | 2006 | J Colloid Interface Sci | pmid:16631185 |
| Wang Y et al. | Chronic effects of different non-esterified fatty acids on pancreatic islets of rats. | 2006 | Endocrine | pmid:16622307 |
| Khairuzzaman A et al. | Zero-order release of aspirin, theophylline and atenolol in water from novel methylcellulose glutarate matrix tablets. | 2006 | Int J Pharm | pmid:16621361 |
| Wang Y et al. | Chain orientation and headgroup structure in Langmuir monolayers of stearic acid and metal stearate (Ag, Co, Zn, and Pb) studied by infrared reflection-absorption spectroscopy. | 2006 | J Chem Phys | pmid:16613467 |
| Mora PC et al. | Differential scanning calorimetry as a screening technique in compatibility studies of DHEA extended release formulations. | 2006 | J Pharm Biomed Anal | pmid:16574368 |
| Hasegawa T et al. | Molecular orientation analysis of a single-monolayer Langmuir-Blodgett film on a thin glass plate by infrared multiple-angle incidence resolution spectrometry. | 2006 | Anal. Chem. | pmid:16536405 |
| Serebryakova MV et al. | Mass spectrometric sequencing and acylation character analysis of C-terminal anchoring segment from Influenza A hemagglutinin. | 2006 | Eur J Mass Spectrom (Chichester) | pmid:16531651 |
| Polat M | Kinetic estimation of the adsorbate distribution on the surface from adsorbed amounts. | 2006 | J Colloid Interface Sci | pmid:16445933 |
| Fernandez-Moya V et al. | Lipid characterization of a high-stearic sunflower mutant displaying a seed stearic acid gradient. | 2006 | J. Agric. Food Chem. | pmid:19127733 |
| Miranda LA et al. | Performance of UASB and DAEB reactors in the anaerobic digestion of synthetic wastewater containing sodium oleate and sodium stereate. | 2006 | Water Sci. Technol. | pmid:16939093 |
| Colla E et al. | Amaranthus cruentus flour edible films: influence of stearic acid addition, plasticizer concentration, and emulsion stirring speed on water vapor permeability and mechanical properties. | 2006 | J. Agric. Food Chem. | pmid:16939322 |
| Renaville B et al. | Eicosapentaenoic acid and 3,10 dithia stearic acid inhibit the desaturation of trans-vaccenic acid into cis-9, trans-11-conjugated linoleic acid through different pathways in Caco-2 and T84 cells. | 2006 | Br. J. Nutr. | pmid:16571147 |
| Fukuda S et al. | Augmentation of vaccenate production and suppression of vaccenate biohydrogenation in cultures of mixed ruminal microbes. | 2006 | J. Dairy Sci. | pmid:16507700 |
| Nazzal S and Khan MA | Controlled release of a self-emulsifying formulation from a tablet dosage form: stability assessment and optimization of some processing parameters. | 2006 | Int J Pharm | pmid:16563673 |
| Swaminathan V et al. | Measurement of the surface energy of lubricated pharmaceutical powders by inverse gas chromatography. | 2006 | Int J Pharm | pmid:16469458 |
| Barman S and Vasudevan S | Contrasting melting behavior of zinc stearate and zinc oleate. | 2006 | J Phys Chem B | pmid:16471580 |
| Wang ZJ et al. | Neuroprotective effect of the stearic acid against oxidative stress via phosphatidylinositol 3-kinase pathway. | 2006 | Chem. Biol. Interact. | pmid:16448636 |
| Salles HC et al. | The venomous secrets of the web droplets from the viscid spiral of the orb-weaver spider Nephila clavipes (Araneae, Tetragnatidae). | 2006 | Chem. Biodivers. | pmid:17193305 |
| Song GY et al. | High-fat feeding reduces endothelium-dependent vasodilation in rats: differential mechanisms for saturated and unsaturated fatty acids? | 2006 | Clin. Exp. Pharmacol. Physiol. | pmid:16895544 |
| El Hagrasy AS et al. | Evaluation of risk and benefit in the implementation of near-infrared spectroscopy for monitoring of lubricant mixing. | 2006 | Pharm Dev Technol | pmid:16895841 |
| Rasmussen HE et al. | Reduction in cholesterol absorption is enhanced by stearate-enriched plant sterol esters in hamsters. | 2006 | J. Nutr. | pmid:17056791 |
| Brouwer DH et al. | Size selective dustiness and exposure; simulated workplace comparisons. | 2006 | Ann Occup Hyg | pmid:16524926 |
| Biswas S et al. | Formation of complex films with water-soluble CTAB molecules. | 2006 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:16549387 |
| Suresh Y and Das UN | Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus. | 2006 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:16412622 |
| Azevedo-Martins AK et al. | Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. | 2006 | Toxicol In Vitro | pmid:16644178 |
| iHoroz BB et al. | Influence of aluminum tristearate and sucrose stearate as the dispersing agents on physical properties and release characteristics of eudragit RS microspheres. | 2006 | AAPS PharmSciTech | pmid:16584146 |
| Hu FQ et al. | A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: properties and in vitro transfection studies. | 2006 | Int J Pharm | pmid:16632285 |
| Govindarajan R et al. | Ionization states in the microenvironment of solid dosage forms: effect of formulation variables and processing. | 2006 | Pharm. Res. | pmid:16933092 |
| Shen Q et al. | Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies. | 2006 | Int J Pharm | pmid:16500056 |
| Söderhäll I et al. | Characterization of a hemocyte intracellular fatty acid-binding protein from crayfish (Pacifastacus leniusculus) and shrimp (Penaeus monodon). | 2006 | FEBS J. | pmid:16734719 |
| Hu FQ et al. | Novel self-aggregates of chitosan oligosaccharide grafted stearic acid: preparation, characterization and protein association. | 2006 | Pharmazie | pmid:16599258 |
| Killen BU and Corrigan OI | Effect of soluble filler on drug release from stearic acid based compacts. | 2006 | Int J Pharm | pmid:16600537 |
| Gelders GG et al. | Potato phosphorylase catalyzed synthesis of amylose-lipid complexes. | 2005 Sep-Oct | Biomacromolecules | pmid:16153100 |
| Parra-Barraza H et al. | Chitosan-cholesterol and chitosan-stearic acid interactions at the air-water interface. | 2005 Sep-Oct | Biomacromolecules | pmid:16153076 |
| Stanisz B | The influence of pharmaceutical excipients on quinapril hydrochloride stability. | 2005 May-Jun | Acta Pol Pharm | pmid:16193811 |
| Menéndez R et al. | In vitro and in vivo study of octacosanol metabolism. | 2005 Mar-Apr | Arch. Med. Res. | pmid:15847942 |
| Staiger H et al. | Fatty acid-induced differential regulation of the genes encoding peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in human skeletal muscle cells that have been differentiated in vitro. | 2005 | Diabetologia | pmid:16132959 |
| Arai T and Hosoi Y | [Determination of magnesium stearate in pharmaceutical preparations using derivatization with 2-nitrophenylhydrazine and HPLC]. | 2005 | Yakugaku Zasshi | pmid:15738629 |
| Watanabe L et al. | Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid. | 2005 | Biochimie | pmid:15760708 |
| Schreiner T et al. | Immediate drug release from solid oral dosage forms. | 2005 | J Pharm Sci | pmid:15761936 |
| Risé P et al. | Differential modulation by simvastatin of the metabolic pathways in the n-9, n-6 and n-3 fatty acid series, in human monocytic and hepatocytic cell lines. | 2005 | Biochem. Pharmacol. | pmid:15763545 |
| Grabowski A et al. | Characterization of long-chain fatty-acid-degrading syntrophic associations from a biodegraded oil reservoir. | 2005 | Res. Microbiol. | pmid:15939576 |
| Jahn T and Steffens KJ | Press chamber coating as external lubrication for high speed rotary presses: lubricant spray rate optimization. | 2005 | Drug Dev Ind Pharm | pmid:16316850 |
| Thijssen MA et al. | Stearic, oleic, and linoleic acids have comparable effects on markers of thrombotic tendency in healthy human subjects. | 2005 | J. Nutr. | pmid:16317124 |
| Wang L et al. | [Synthesis, characterization and evaluation of octadecyl ester-bonded monolithic column]. | 2005 | Se Pu | pmid:16350795 |
| Hackl H et al. | Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. | 2005 | Genome Biol. | pmid:16420668 |
| Navaneethan CV et al. | Application of powder rheometer to determine powder flow properties and lubrication efficiency of pharmaceutical particulate systems. | 2005 | AAPS PharmSciTech | pmid:16353997 |
| Soares LA et al. | Dry granulation and compression of spray-dried plant extracts. | 2005 | AAPS PharmSciTech | pmid:16353993 |
| Tatavarti AS et al. | Assessment of NIR spectroscopy for nondestructive analysis of physical and chemical attributes of sulfamethazine bolus dosage forms. | 2005 | AAPS PharmSciTech | pmid:16353969 |
| Salzman RA et al. | Transcriptional profiling of sorghum induced by methyl jasmonate, salicylic acid, and aminocyclopropane carboxylic acid reveals cooperative regulation and novel gene responses. | 2005 | Plant Physiol. | pmid:15863699 |
| Wyttenbach N et al. | Drug-excipient compatibility testing using a high-throughput approach and statistical design. | 2005 | Pharm Dev Technol | pmid:16370179 |
| Lee J | Intrinsic adhesion properties of poly(vinyl pyrrolidone) to pharmaceutical materials: humidity effect. | 2005 | Macromol Biosci | pmid:16245267 |
| Lad MD et al. | Protein-lipid interactions at the air/water interface. | 2005 | Phys Chem Chem Phys | pmid:16273149 |
| Vueba ML et al. | Role of cellulose ether polymers on ibuprofen release from matrix tablets. | 2005 | Drug Dev Ind Pharm | pmid:16207613 |
| Turkoglu M et al. | Evaluation of hexagonal boron nitride as a new tablet lubricant. | 2005 | Pharm Dev Technol | pmid:16176018 |
| Chen Y et al. | Side reactions in controlling the quality, yield, and stability of high quality colloidal nanocrystals. | 2005 | J. Am. Chem. Soc. | pmid:16173766 |
| Wang X et al. | Solid state characteristics of ternary solid dispersions composed of PVP VA64, Myrj 52 and itraconazole. | 2005 | Int J Pharm | pmid:16105723 |
| Dong J et al. | Silver carboxylate nanostructure nucleation and growth on AgBr crystals. | 2005 | Nanotechnology | pmid:21727481 |
| Verma RK and Garg S | Selection of excipients for extended release formulations of glipizide through drug-excipient compatibility testing. | 2005 | J Pharm Biomed Anal | pmid:15967291 |
| Harris RK et al. | Quantification of bambuterol hydrochloride in a formulated product using solid-state NMR. | 2005 | J Pharm Biomed Anal | pmid:15869858 |
| Shim SK et al. | Analysis of cellular fatty acids in Orientia tsutsugamushi as taxonomic markers. | 2005 | Microbiol. Immunol. | pmid:15840959 |
| Tomassetti M et al. | Thermal analysis study of the interactions between acetaminophen and excipients in solid dosage forms and in some binary mixtures. | 2005 | J Pharm Biomed Anal | pmid:15862672 |
| Savickas A and Bernatoniene J | Optimization of "Askoeziuofito" tablets. | 2005 | Medicina (Kaunas) | pmid:15827390 |
| Staiger K et al. | Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells. | 2005 | Diabetologia | pmid:16078017 |
| Ibáñez L et al. | Population-based drug-induced agranulocytosis. | 2005 | Arch. Intern. Med. | pmid:15851637 |
| Morais S et al. | Dietary protein:lipid ratio and lipid nature affects fatty acid absorption and metabolism in a teleost larva. | 2005 | Br. J. Nutr. | pmid:16022750 |
| Egerton TA et al. | Characterization of TiO2 nanoparticles surface modified with aluminum stearate. | 2005 | Langmuir | pmid:15780001 |
| Armoni M et al. | Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements. | 2005 | J. Biol. Chem. | pmid:16096283 |
| Fujii M et al. | Preparation, characterization, and tableting of a solid dispersion of indomethacin with crospovidone. | 2005 | Int J Pharm | pmid:15778052 |
| Desbrosses GG et al. | Lotus japonicus metabolic profiling. Development of gas chromatography-mass spectrometry resources for the study of plant-microbe interactions. | 2005 | Plant Physiol. | pmid:15749991 |
| Citadini AP et al. | EPR studies of chlorocatechol 1,2-dioxygenase: evidences of iron reduction during catalysis and of the binding of amphipatic molecules. | 2005 | Biophys. J. | pmid:15722436 |
| Nkondjock A et al. | Specific fatty acid intake and the risk of pancreatic cancer in Canada. | 2005 | Br. J. Cancer | pmid:15685231 |
| Donoso M and Ghaly ES | Prediction of tablets disintegration times using near-infrared diffuse reflectance spectroscopy as a nondestructive method. | 2005 | Pharm Dev Technol | pmid:15926669 |
| Katsuta Y et al. | Unsaturated fatty acids induce calcium influx into keratinocytes and cause abnormal differentiation of epidermis. | 2005 | J. Invest. Dermatol. | pmid:15854043 |
| Green RL et al. | Comparison of near-infrared and laser-induced breakdown spectroscopy for determination of magnesium stearate in pharmaceutical powders and solid dosage forms. | 2005 | Appl Spectrosc | pmid:15901316 |
| Sahin N et al. | Lipase-catalyzed acidolysis of tripalmitin with hazelnut oil fatty acids and stearic acid to produce human milk fat substitutes. | 2005 | J. Agric. Food Chem. | pmid:15998148 |
| Berry SE and Sanders TA | Influence of triacylglycerol structure of stearic acid-rich fats on postprandial lipaemia. | 2005 | Proc Nutr Soc | pmid:15960865 |
| Lin WC et al. | Determination of carotenoids in spear shrimp shells (Parapenaeopsis hardwickii) by liquid chromatography. | 2005 | J. Agric. Food Chem. | pmid:15969489 |
| Fernández-Moya V et al. | Oils from improved high stearic acid sunflower seeds. | 2005 | J. Agric. Food Chem. | pmid:15969513 |
| Mirmehrabi M and Rohani S | An approach to solvent screening for crystallization of polymorphic pharmaceuticals and fine chemicals. | 2005 | J Pharm Sci | pmid:15929066 |
| Jiang RG et al. | [Effect of surface modification on surface energy of lactose and performance of dry powder inhalations]. | 2005 | Yao Xue Xue Bao | pmid:16011271 |
| Zhao XY et al. | [Studies on chemical constituents from rhizome of Impatiens pritzellii var. hupehensis]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16011279 |
| Patil S and Chan C | Palmitic and stearic fatty acids induce Alzheimer-like hyperphosphorylation of tau in primary rat cortical neurons. | 2005 | Neurosci. Lett. | pmid:15939536 |
| MuzÃková J and PálenÃk L | [A study of the properties of compacts from a mixed dry binder on the base of alpha-lactose monohydrate and microcrystalline cellulose]. | 2005 | Ceska Slov Farm | pmid:15945458 |
| Zhu S et al. | Acid soap and phase behavior of stearic acid and triethanolamine stearate. | 2005 | J Phys Chem B | pmid:16852443 |
| Le Jossic-Corcos C et al. | Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids. | 2005 | Biochem. J. | pmid:15473864 |
| Mishra R and Simonson MS | Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G. | 2005 | Cardiovasc Diabetol | pmid:15642122 |
| Hong J et al. | The short-term effect of fatty acids on glucagon secretion is influenced by their chain length, spatial configuration, and degree of unsaturation: studies in vitro. | 2005 | Metab. Clin. Exp. | pmid:16154432 |
| Jurkiewicz K | Adsorptive bubble separation of zinc and cadmium cations in presence of ferric and aluminum hydroxides. | 2005 | J Colloid Interface Sci | pmid:15897071 |
| Hoppu U et al. | Breast milk fatty acid composition is associated with development of atopic dermatitis in the infant. | 2005 | J. Pediatr. Gastroenterol. Nutr. | pmid:16131990 |
| Choi MY et al. | Pheromone biosynthetic pathways in the moths Heliothis subflexa and Heliothis virescens. | 2005 | Arch. Insect Biochem. Physiol. | pmid:15898118 |
| Iwahashi M et al. | Dynamical dimer structure and liquid structure of fatty acids in their binary liquid mixture: decanoic/octadecanoic acid and decanoic/dodecanoic acid systems. | 2005 | Chem. Phys. Lipids | pmid:15642581 |