stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Hisazumi J et al. Quantification of pharmaceutical polymorphs and prediction of dissolution rate using theophylline tablet by terahertz spectroscopy. 2011 Chem. Pharm. Bull. pmid:21467671
Almer G et al. Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. 2011 Int J Nanomedicine pmid:21753879
Varshosaz J et al. Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats. 2011 Daru pmid:22615647
Chaturvedi K et al. Floating matrix dosage form for propranolol hydrochloride based on gas formation technique: development and in vitro evaluation. 2010 Oct-Dec Sci Pharm pmid:21179326
Terekhova EA et al. [Stearic acid methyl ether: a new extracellular metabolite of the obligate methylotrophic bacterium Methylophilus quaylei]. 2010 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:20391761
Kristó K et al. Effect of lubricant on spreading of coating liquid on surface of tablets containing pancreatin. 2010 Jul-Aug Pharm Dev Technol pmid:19772392
Badawy SI et al. Effect of spray-dried mannitol on the performance of microcrystalline cellulose-based wet granulated tablet formulation. 2010 Jul-Aug Pharm Dev Technol pmid:20088677
Kaur G et al. Chitosan-carboxymethyl tamarind kernel powder interpolymer complexation: investigations for colon drug delivery. 2010 Jan-Mar Sci Pharm pmid:21179370
Stanisz B et al. Influence of humidity and hydroxypropyl cellulose, hydroxypropylmethyl cellulose, glyceryl behenate or magnesium stearate on the degradation kinetics of quinapril hydrochloride in solid phase. 2010 Jan-Feb Acta Pol Pharm pmid:20210086
Aburahma MH et al. Preparation and in vitro/in vivo characterization of porous sublingual tablets containing ternary kneaded solid system of vinpocetine with î-cyclodextrin and hydroxy Acid. 2010 Apr-Jun Sci Pharm pmid:21179352
Singh B et al. Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride. 2010 Apr-Jun Sci Pharm pmid:21179349
Chen Y et al. A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. 2010 Appl Spectrosc pmid:20925991
Mukherjee S et al. Stearic acid delivery to corneum from a mild and moisturizing cleanser. 2010 J Cosmet Dermatol pmid:20883293
Rawat MK et al. Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. 2010 Ther Deliv pmid:22816120
Patra S et al. In vitro evaluation of domperidone mouth dissolving tablets. 2010 Indian J Pharm Sci pmid:21969764
Shen J et al. Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: Improving in vivo ocular distribution. 2010 Int J Pharm pmid:20934499
Alizadeh M et al. The effect of hypocaloric diet enriched in legumes with or without L-arginine and selenium on anthropometric measures in central obese women. 2010 J Res Med Sci pmid:21526106
Araújo J et al. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. 2010 Int J Pharm pmid:20362042
Bender K et al. Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. 2010 Reproduction pmid:20385782
Pedersen PJ et al. Liposomal formulation of retinoids designed for enzyme triggered release. 2010 J. Med. Chem. pmid:20405849
Liew CV et al. In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. 2010 Int J Pharm pmid:19922776
Ohwoavworhua FO and Adelakun TA Non-wood Fibre Production of Microcrystalline Cellulose from Sorghum caudatum: Characterisation and Tableting Properties. 2010 Indian J Pharm Sci pmid:21188036
Luan L et al. [Studies on the chemical constituents of extract with water from Forsythia suspensa]. 2010 Zhong Yao Cai pmid:20575415
Contreras GA et al. Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. 2010 J. Dairy Sci. pmid:20494158
Karande AD et al. In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. 2010 Int J Pharm pmid:20558264
Kim IS and Oh IJ Preparation and characterization of stearic acid-pullulan nanoparticles. 2010 Arch. Pharm. Res. pmid:20512475
Wang J et al. Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. 2010 J Pharm Sci pmid:20533436
Lyra A et al. Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes. 2010 BMC Gastroenterol pmid:20849659
Shishu VR et al. Development of taste masked oral formulation of ornidazole. 2010 Indian J Pharm Sci pmid:20838525
Gohel MC et al. Fabrication and Evaluation of Bi-layer Tablet Containing Conventional Paracetamol and Modified Release Diclofenac Sodium. 2010 Indian J Pharm Sci pmid:20838522
Phaechamud T et al. Preparation of Coated Valproic Acid and Sodium Valproate Sustained-release Matrix Tablets. 2010 Indian J Pharm Sci pmid:20838520
Huthmacher C et al. Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. 2010 BMC Syst Biol pmid:20807400
Do PT et al. The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. 2010 Plant Physiol. pmid:20841452
Harvey KA et al. Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. 2010 J. Lipid Res. pmid:20852092
Blanco M and Peguero A Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. 2010 J Pharm Biomed Anal pmid:20044229
Swanson EJ et al. Phospholipid-stabilized microbubble foam for injectable oxygen delivery. 2010 Langmuir pmid:20873807
Howell AB et al. Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. 2010 BMC Infect. Dis. pmid:20398248
Yasuda A et al. Self-organizing map analysis using multivariate data from theophylline powders predicted by a thin-plate spline interpolation. 2010 J Pharm Sci pmid:20845452
UÄŸurlu T et al. Effects of lubricants on binary direct compression mixtures. 2010 Drug Discov Ther pmid:22491169
Shaikh SA et al. Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. 2010 J Adv Pharm Technol Res pmid:22247846
Tiwari G et al. Cyclodextrins in delivery systems: Applications. 2010 J Pharm Bioallied Sci pmid:21814436
van den Berg SA et al. High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity. 2010 Nutr Metab (Lond) pmid:20346174
Choi JN et al. Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. 2010 J. Agric. Food Chem. pmid:20225861
Desando MA et al. Proton magnetic relaxation and the aggregation of n-octylammonium n-octadecanoate surfactant in deuterochloroform solution. 2010 J Colloid Interface Sci pmid:20223468
Xing Z et al. The fabrication of novel nanobubble ultrasound contrast agent for potential tumor imaging. 2010 Nanotechnology pmid:20220227
Li Y et al. Preparation and characterization of coverage-controlled CaCO3 nanoparticles. 2010 J Colloid Interface Sci pmid:20202642
Romanowicz L and Bańkowski E Sphingolipids of human umbilical cord vein and their alteration in preeclampsia. 2010 Mol. Cell. Biochem. pmid:20155487
Kordyukova LV et al. Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. 2010 Virology pmid:20006369
Abdel-Mottaleb MM et al. In vitro drug release mechanism from lipid nanocapsules (LNC). 2010 Int J Pharm pmid:20149853
Raeside JI and Christie HL Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands. 2010 Biochem. Biophys. Res. Commun. pmid:20875396