MeSH term | MeSH ID | Detail |
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Eczema, Dyshidrotic | D011146 | 1 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kogure K et al. | Effect of dicetylphosphate or stearic acid on spontaneous transfer of protein from influenza virus-infected cells to dimyristoylphosphatidylcholine liposomes. | 1997 | Biochim. Biophys. Acta | pmid:9370255 |
Piel J et al. | Cellulysin from the plant parasitic fungus Trichoderma viride elicits volatile biosynthesis in higher plants via the octadecanoid signalling cascade. | 1997 | FEBS Lett. | pmid:9369200 |
Ali I and Steele JE | Fatty acids stimulate trehalose synthesis in trophocytes of the cockroach (Periplaneta americana) fat body. | 1997 | Gen. Comp. Endocrinol. | pmid:9356224 |
Neubert R et al. | Structure of stratum corneum lipids characterized by FT-Raman spectroscopy and DSC. II. Mixtures of ceramides and saturated fatty acids. | 1997 | Chem. Phys. Lipids | pmid:9353900 |
Dürig T and Fassihi R | Mechanistic evaluation of binary effects of magnesium stearate and talc as dissolution retardants at 85% drug loading in an experimental extended-release formulation. | 1997 | J Pharm Sci | pmid:9344163 |
Yamashita T et al. | [Studies on erythromycin stearate capsules (OE-7) (author's transl)]. | 1976 | Jpn J Antibiot | pmid:933342 |
Bondarenko LB et al. | Fatty acids hydroxamic derivatives as inhibitors of 5-lipoxygenase. | 1997 | Adv. Exp. Med. Biol. | pmid:9321992 |
West RR and Stafford DA | Occupational exposures and haematological abnormalities among ordnance factory workers: a case control study. | 1997 | Leuk. Res. | pmid:9301689 |
Moers A and Schrezenmeir J | Palmitic acid but not stearic acid inhibits NO-production in endothelial cells. | 1997 | Exp. Clin. Endocrinol. Diabetes | pmid:9288552 |
Wagner K et al. | Influence of duodenal infusion of nicotinic acid on the milk fat composition of dairy cows. | 1997 | Arch Tierernahr | pmid:9272222 |