stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Obesity, Abdominal D056128 3 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Snoeren TA et al. Multidisciplinary approach to unravelling the relative contribution of different oxylipins in indirect defense of Arabidopsis thaliana. 2009 J. Chem. Ecol. pmid:19798534
Atherton HJ et al. Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse. 2009 Mol. Syst. Biol. pmid:19357638
Sahoo RR and Biswas SK Frictional response of fatty acids on steel. 2009 J Colloid Interface Sci pmid:19232636
Martínez-Force E et al. Influence of specific fatty acids on the asymmetric distribution of saturated fatty acids in sunflower (Helianthus annuus L.) triacylglycerols. 2009 J. Agric. Food Chem. pmid:19166295
Chen JJ et al. seco-Abietane diterpenoids, a phenylethanoid derivative, and antitubercular constituents from Callicarpa pilosissima. 2009 J. Nat. Prod. pmid:19193025
Peters GH et al. Effects of fatty acid inclusion in a DMPC bilayer membrane. 2009 J Phys Chem B pmid:19195101
Sugisawa K et al. Rapid quantitative analysis of magnesium stearate in pharmaceutical powders and solid dosage forms by atomic absorption: method development and application in product manufacturing. 2009 J Pharm Biomed Anal pmid:19195812
Tuomasjukka SS et al. Regio-distribution of stearic acid is not conserved in chylomicrons after ingestion of randomised, stearic acid-rich fat in a single meal. 2009 J. Nutr. Biochem. pmid:19195862
Parlati C et al. Pulmonary spray dried powders of tobramycin containing sodium stearate to improve aerosolization efficiency. 2009 Pharm. Res. pmid:19184617
Matharu Z et al. Langmuir-Blodgett film based on MEH-PPV for cholesterol biosensor. 2009 Anal. Chim. Acta pmid:19185127
HÃ¥versen L et al. Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. 2009 Atherosclerosis pmid:18599066
Roberts R et al. Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans. 2009 Diabetologia pmid:19252892
Yuan H et al. Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles. 2009 Colloids Surf B Biointerfaces pmid:19185474
Cha D et al. Analysis of fatty acids in sputum from patients with pulmonary tuberculosis using gas chromatography-mass spectrometry preceded by solid-phase microextraction and post-derivatization on the fiber. 2009 J Chromatogr A pmid:19171347
Mermigkis C et al. A green oral appliance. 2009 Eur. Respir. J. pmid:19181918
Boros LG et al. Ethanol diversely alters palmitate, stearate, and oleate metabolism in the liver and pancreas of rats using the deuterium oxide single tracer. 2009 Pancreas pmid:19248221
Ishitsuka Y et al. Effects of bolus injection of soybean-based fat emulsion and fatty acids on pulmonary gas exchange function. 2009 Biol. Pharm. Bull. pmid:19252304
Pingali KC et al. Use of a static eliminator to improve powder flow. 2009 Int J Pharm pmid:19266628
Yadav VR et al. Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease. 2009 J. Pharm. Pharmacol. pmid:19222903
Okuda Y et al. A new formulation for orally disintegrating tablets using a suspension spray-coating method. 2009 Int J Pharm pmid:19686825
Asgary S et al. Evaluation of fatty acid content of some Iranian fast foods with emphasis on trans fatty acids. 2009 Asia Pac J Clin Nutr pmid:19713177
Yamamura T et al. Effects of automated external lubrication on tablet properties and the stability of eprazinone hydrochloride. 2009 Int J Pharm pmid:19059327
Plumley C et al. Nifedipine nanoparticle agglomeration as a dry powder aerosol formulation strategy. 2009 Int J Pharm pmid:19015016
Burkhardt M et al. Macroscopic properties and microstructure of HSA based organogels: sensitivity to polar additives. 2009 J Colloid Interface Sci pmid:19144353
Huang J et al. Quality by design case study: an integrated multivariate approach to drug product and process development. 2009 Int J Pharm pmid:19664698
Cao C et al. [Chemical study on petroleum ether portion of Sarcandra hainanensis]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19639789
Gupta A et al. Difference in the lubrication efficiency of bovine and vegetable-derived magnesium stearate during tabletting. 2009 AAPS PharmSciTech pmid:19390976
Sakuradani E et al. Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4. 2009 Appl. Microbiol. Biotechnol. pmid:19415268
Chen JM et al. [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. 2009 Ying Yong Sheng Tai Xue Bao pmid:20353052
Gohel M and Bariya SH Advanced formulation design of venlafaxine hydrochloride coated and triple-layer tablets containing hypromellose. 2009 Pharm Dev Technol pmid:19883254
Chen CY et al. Chemical constituents from the whole plant of Gaultheria itoana Hayata. 2009 Chem. Biodivers. pmid:19842133
Staiger H et al. Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans. 2009 Diabetes pmid:19074989
Kadotani A et al. Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes. 2009 Am. J. Physiol. Endocrinol. Metab. pmid:19755671
Bao Y et al. Metabonomic variations in the drug-treated type 2 diabetes mellitus patients and healthy volunteers. 2009 J. Proteome Res. pmid:19714868
Madgulkar AR et al. Formulation and optimization of sustained release tablets of venlafaxine resinates using response surface methodology. 2009 Indian J Pharm Sci pmid:20502544
Mukherjee S et al. Solid lipid nanoparticles: a modern formulation approach in drug delivery system. 2009 Indian J Pharm Sci pmid:20502539
Arayne MS et al. Spectrophotometric Quantitation of Metformin in Bulk Drug and Pharmaceutical Formulations using Multivariate Technique. 2009 Indian J Pharm Sci pmid:20490308
Leonardi R et al. Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. 2009 J. Biol. Chem. pmid:19666474
Swamy PV et al. Preparation and evaluation of orodispersible tablets of pheniramine maleate by effervescent method. 2009 Indian J Pharm Sci pmid:20336216
Costa MC et al. The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. 2009 Chem. Phys. Lipids pmid:19520067
Prajapati ST et al. Studies on formulation and in vitro evaluation of floating matrix tablets of domperidone. 2009 Indian J Pharm Sci pmid:20177450
Puzanowska-Tarasiewicz H et al. Spectroscopic and electrochemical analysis of psychotropic drugs. 2009 Indian J Pharm Sci pmid:20177449
Wei Y et al. Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. 2009 Mol. Cell. Biochem. pmid:19444596
Mahmoud AM et al. Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate. 2009 Int J Anal Chem pmid:20140080
Evans LM et al. Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice. 2009 Clin. Exp. Metastasis pmid:19267249
Mahmoud AM New sensitive kinetic spectrophotometric methods for determination of omeprazole in dosage forms. 2009 Int J Anal Chem pmid:20140076
Darwish IA et al. New spectrophotometric and fluorimetric methods for determination of fluoxetine in pharmaceutical formulations. 2009 Int J Anal Chem pmid:20107560
Darwish IA et al. Simple spectrophotometric method for determination of paroxetine in tablets using 1,2-naphthoquinone-4-sulphonate as a chromogenic reagent. 2009 Int J Anal Chem pmid:20107559
Guo L and Qing Li G Olfactory perception of oviposition-deterring fatty acids and their methyl esters by the Asian corn borer, Ostrinia furnacalis. 2009 J. Insect Sci. pmid:20053122
Kalman DS et al. A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans-based product on functional intestinal gas symptoms. 2009 BMC Gastroenterol pmid:19922649
Fostok SF et al. Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus. 2009 BMC Complement Altern Med pmid:19917107
Evans LM et al. Stearate preferentially induces apoptosis in human breast cancer cells. 2009 Nutr Cancer pmid:19838949
Mukherjee S and Datta A Morphology and structural evolution in cobalt stearate Langmuir-Blodgett films. 2009 J Nanosci Nanotechnol pmid:19928206
Yarkala S et al. Role of excipients on N-oxide raloxifene generation from raloxifene-excipients binary mixtures. 2009 Chem. Pharm. Bull. pmid:19801885
Jayakumar OD et al. Water dispersible Fe3O4 nanoparticles carrying doxorubicin for cancer therapy. 2009 J Nanosci Nanotechnol pmid:19908532
Fujita M et al. Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine. 2009 Chem. Pharm. Bull. pmid:19801864
Ye YQ et al. Enhanced cytotoxicity of core modified chitosan based polymeric micelles for doxorubicin delivery. 2009 J Pharm Sci pmid:18563810
Gängler P et al. In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel. 2009 BMC Oral Health pmid:19799785
Amorim EA et al. Effect of cholesterol or cholesteryl conjugates on the cryosurvival of bull sperm. 2009 Cryobiology pmid:19159623
Yonezawa T et al. Saturated fatty acids stimulate and insulin suppresses BMCP1 expression in bovine mammary epithelial cells. 2009 Biochem. Biophys. Res. Commun. pmid:19852928
Hellemans KH et al. Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase. 2009 PLoS ONE pmid:19787047
Artwohl M et al. Fatty acids induce apoptosis in human smooth muscle cells depending on chain length, saturation, and duration of exposure. 2009 Atherosclerosis pmid:18597758
Masuoka HC et al. Mcl-1 degradation during hepatocyte lipoapoptosis. 2009 J. Biol. Chem. pmid:19734538
Rittermeier A et al. The formation of colloidal copper nanoparticles stabilized by zinc stearate: one-pot single-step synthesis and characterization of the core-shell particles. 2009 Phys Chem Chem Phys pmid:19756292
Jiang L et al. Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway. 2009 PLoS ONE pmid:19727392
Lakshmi RV and Basu BJ Fabrication of superhydrophobic sol-gel composite films using hydrophobically modified colloidal zinc hydroxide. 2009 J Colloid Interface Sci pmid:19720382
Alagna F et al. Comparative 454 pyrosequencing of transcripts from two olive genotypes during fruit development. 2009 BMC Genomics pmid:19709400
Lozano MM and Longo ML Microbubbles coated with disaturated lipids and DSPE-PEG2000: phase behavior, collapse transitions, and permeability. 2009 Langmuir pmid:19708150
Spaniol B et al. Compressional behavior of a mixture of granules containing high load of Phyllanthus niruri spray-dried extract and granules of adjuvants: comparison between eccentric and rotary tablet machines. 2009 AAPS PharmSciTech pmid:19662537
Mukherjee S et al. Chemistry at air/water interface versus reaction in a flask: tuning molecular conformation in thin films. 2009 Langmuir pmid:19708145
Kantartzis K et al. Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene. 2009 Diabetes pmid:19651814
Cha KH et al. Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia. 2009 Arch. Pharm. Res. pmid:20091273
Hesta M et al. The effect of vitamin C supplementation in healthy dogs on antioxidative capacity and immune parameters. 2009 J Anim Physiol Anim Nutr (Berl) pmid:19386005
Thumma S and Repka MA Compatibility studies of promethazine hydrochloride with tablet excipients by means of thermal and non-thermal methods. 2009 Pharmazie pmid:19348341
Bolhuis GK et al. Compaction properties of isomalt. 2009 Eur J Pharm Biopharm pmid:19327398
Staiger K et al. Protein kinase C iota mediates lipid-induced apoptosis of human coronary artery endothelial cells. 2009 Microvasc. Res. pmid:19327373
Singh R et al. Mapping quantitative trait loci (QTLs) for fatty acid composition in an interspecific cross of oil palm. 2009 BMC Plant Biol. pmid:19706196
Alloatti A et al. Chemical evaluation of fatty acid desaturases as drug targets in Trypanosoma cruzi. 2009 Int. J. Parasitol. pmid:19249306
Ishikado A et al. Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells. 2009 Atherosclerosis pmid:19215923
Ussher JR et al. Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. 2009 Diabetes pmid:19478144
Yang Y et al. Radial-position-controlled doping of CdS/ZnS core/shell nanocrystals: surface effects and position-dependent properties. 2009 Chemistry pmid:19206119
Monajjemzadeh F et al. Assessment of feasibility of maillard reaction between baclofen and lactose by liquid chromatography and tandem mass spectrometry, application to pre formulation studies. 2009 AAPS PharmSciTech pmid:19455427
Durak D and Kalender Y Fine structure and chemical analysis of the metathoracic scent gland secretion in Graphosoma lineatum (Linnaeus, 1758) (Heteroptera, Pentatomidae). 2009 C. R. Biol. pmid:19200924
Anderson BM and Ma DW Are all n-3 polyunsaturated fatty acids created equal? 2009 Lipids Health Dis pmid:19664246
Nyadong L et al. Combining two-dimensional diffusion-ordered nuclear magnetic resonance spectroscopy, imaging desorption electrospray ionization mass spectrometry, and direct analysis in real-time mass spectrometry for the integral investigation of counterfeit pharmaceuticals. 2009 Anal. Chem. pmid:19453162
Wu Y et al. Metabonomic profile of rats with acute liver rejection. 2009 OMICS pmid:19196102
Meng W et al. A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. 2009 Trials pmid:19419555
Kaye RS et al. Simultaneously manufactured nano-in-micro (SIMANIM) particles for dry-powder modified-release delivery of antibodies. 2009 J Pharm Sci pmid:19189420
Brach Del Prever EM et al. UHMWPE for arthroplasty: past or future? 2009 J Orthop Traumatol pmid:19384628
Sobal G et al. Uptake of 99mTc-labeled chondroitin sulfate by chondrocytes and cartilage: a promising agent for imaging of cartilage degeneration? 2009 Nucl. Med. Biol. pmid:19181270
Marvey BB Extrudate versus powder silica alumina as support for Re₂O₇ catalyst in the metathesis of seed oil-derivatives - a comparison. 2009 Int J Mol Sci pmid:19333442
Chin PT et al. Highly luminescent ultranarrow Mn doped ZnSe nanowires. 2009 Nano Lett. pmid:19146460
Begat P et al. The role of force control agents in high-dose dry powder inhaler formulations. 2009 J Pharm Sci pmid:19067395
Pérez-Berná AJ et al. Screening a peptide library by DSC and SAXD: comparison with the biological function of the parent proteins. 2009 PLoS ONE pmid:19194494
Kaye RS et al. Development and testing of particulate formulations for the nasal delivery of antibodies. 2009 J Control Release pmid:19059291
Figueiras AN et al. Epicuticular lipids induce aggregation in Chagas disease vectors. 2009 Parasit Vectors pmid:19173716
Ren X et al. Nonionic surfactants are strong inhibitors of cytochrome P450 3A biotransformation activity in vitro and in vivo. 2009 Eur J Pharm Sci pmid:19041719
García MS et al. Development of membrane selective electrode for determination of the antipsychotic sulpiride in pharmaceuticals and urine. 2009 Sensors (Basel) pmid:22408528
Rico S et al. Ebastine in the light of CONGA recommendations for the development of third-generation antihistamines. 2009 J Asthma Allergy pmid:21437146
Chen CJ et al. Preparation of Monodisperse Iron Oxide Nanoparticles via the Synthesis and Decomposition of Iron Fatty Acid Complexes. 2009 Nanoscale Res Lett pmid:20628451