| MeSH term | MeSH ID | Detail |
|---|---|---|
| Obesity, Abdominal | D056128 | 3 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sahoo RR and Biswas SK | Frictional response of fatty acids on steel. | 2009 | J Colloid Interface Sci | pmid:19232636 |
| MartÃnez-Force E et al. | Influence of specific fatty acids on the asymmetric distribution of saturated fatty acids in sunflower (Helianthus annuus L.) triacylglycerols. | 2009 | J. Agric. Food Chem. | pmid:19166295 |
| HÃ¥versen L et al. | Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. | 2009 | Atherosclerosis | pmid:18599066 |
| Roberts R et al. | Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans. | 2009 | Diabetologia | pmid:19252892 |
| Okuda Y et al. | A new formulation for orally disintegrating tablets using a suspension spray-coating method. | 2009 | Int J Pharm | pmid:19686825 |
| Asgary S et al. | Evaluation of fatty acid content of some Iranian fast foods with emphasis on trans fatty acids. | 2009 | Asia Pac J Clin Nutr | pmid:19713177 |
| Gupta A et al. | Difference in the lubrication efficiency of bovine and vegetable-derived magnesium stearate during tabletting. | 2009 | AAPS PharmSciTech | pmid:19390976 |
| Sakuradani E et al. | Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19415268 |
| Chen JM et al. | [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. | 2009 | Ying Yong Sheng Tai Xue Bao | pmid:20353052 |
| Costa MC et al. | The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. | 2009 | Chem. Phys. Lipids | pmid:19520067 |
| Wei Y et al. | Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. | 2009 | Mol. Cell. Biochem. | pmid:19444596 |
| Kalman DS et al. | A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans-based product on functional intestinal gas symptoms. | 2009 | BMC Gastroenterol | pmid:19922649 |
| Fostok SF et al. | Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus. | 2009 | BMC Complement Altern Med | pmid:19917107 |
| Evans LM et al. | Stearate preferentially induces apoptosis in human breast cancer cells. | 2009 | Nutr Cancer | pmid:19838949 |
| Yarkala S et al. | Role of excipients on N-oxide raloxifene generation from raloxifene-excipients binary mixtures. | 2009 | Chem. Pharm. Bull. | pmid:19801885 |
| Fujita M et al. | Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine. | 2009 | Chem. Pharm. Bull. | pmid:19801864 |
| Ye YQ et al. | Enhanced cytotoxicity of core modified chitosan based polymeric micelles for doxorubicin delivery. | 2009 | J Pharm Sci | pmid:18563810 |
| Cha KH et al. | Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia. | 2009 | Arch. Pharm. Res. | pmid:20091273 |
| Thumma S and Repka MA | Compatibility studies of promethazine hydrochloride with tablet excipients by means of thermal and non-thermal methods. | 2009 | Pharmazie | pmid:19348341 |
| Bolhuis GK et al. | Compaction properties of isomalt. | 2009 | Eur J Pharm Biopharm | pmid:19327398 |
| Staiger K et al. | Protein kinase C iota mediates lipid-induced apoptosis of human coronary artery endothelial cells. | 2009 | Microvasc. Res. | pmid:19327373 |
| Alloatti A et al. | Chemical evaluation of fatty acid desaturases as drug targets in Trypanosoma cruzi. | 2009 | Int. J. Parasitol. | pmid:19249306 |
| Ishikado A et al. | Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells. | 2009 | Atherosclerosis | pmid:19215923 |
| Monajjemzadeh F et al. | Assessment of feasibility of maillard reaction between baclofen and lactose by liquid chromatography and tandem mass spectrometry, application to pre formulation studies. | 2009 | AAPS PharmSciTech | pmid:19455427 |
| Nyadong L et al. | Combining two-dimensional diffusion-ordered nuclear magnetic resonance spectroscopy, imaging desorption electrospray ionization mass spectrometry, and direct analysis in real-time mass spectrometry for the integral investigation of counterfeit pharmaceuticals. | 2009 | Anal. Chem. | pmid:19453162 |
| Meng W et al. | A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. | 2009 | Trials | pmid:19419555 |
| Brach Del Prever EM et al. | UHMWPE for arthroplasty: past or future? | 2009 | J Orthop Traumatol | pmid:19384628 |
| Qureshi J et al. | Chronomodulated drug delivery system of salbutamol sulphate for the treatment of nocturnal asthma. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046744 |
| Issa MM et al. | Novel atomic absorption spectrometric and rapid spectrophotometric methods for the quantitation of paracetamol in saliva: application to pharmacokinetic studies. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046743 |
| Gohel MC and Sarvaiya KG | Exploration of cold extrusion for the preparation of enteric minitablets of isoniazid. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046736 |
| Gohel MC et al. | Modulation of venlafaxine hydrochloride release from press coated matrix tablet. | 2008 May-Jun | Indian J Pharm Sci | pmid:20046735 |
| Bhise SB and Aloorkar NH | Formulation and in vitro Evaluation of Floating Capsules of Theophylline. | 2008 Mar-Apr | Indian J Pharm Sci | pmid:20046717 |
| Setty CM et al. | Development of fast dispersible aceclofenac tablets: effect of functionality of superdisintegrants. | 2008 Mar-Apr | Indian J Pharm Sci | pmid:20046709 |
| Masareddy RS et al. | Development of mouth dissolving tablets of clozapine using two different techniques. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046788 |
| Syed AA and Syeda A | Spectrophotometric determination of certain benzimidazole proton pump inhibitors. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046782 |
| Baldania SL et al. | RP-HPLC Estimation of Risperidone in Tablet Dosage Forms. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046778 |
| Ganesh S et al. | In vitro Evaluation of the Effect of Combination of Hydrophilic and Hydrophobic Polymers on Controlled Release Zidovudine Matrix Tablets. | 2008 Jul-Aug | Indian J Pharm Sci | pmid:20046771 |
| Cocchi M et al. | [Membrane platelet fatty acids: biochemical characterisation of the ischemic cardiovascular disease, characteristics of the paediatric age, through an artificial neural network interpretation]. | 2008 Jan-Feb | Pediatr Med Chir | pmid:18491675 |
| Whitby CP et al. | Effect of oil soluble surfactant in emulsions stabilised by clay particles. | 2008 | J Colloid Interface Sci | pmid:18452938 |
| He X et al. | Formulation development and process scale up of a high shear wet granulation formulation containing a poorly wettable drug. | 2008 | J Pharm Sci | pmid:18449937 |
| John Wallace R | Gut microbiology - broad genetic diversity, yet specific metabolic niches. | 2008 | Animal | pmid:22443591 |
| Chen Y et al. | Isolation of 5-hydroxypyrrolidin-2-one and other constituents from the young fronds of Pteridium aquilinum. | 2008 | J Nat Med | pmid:18437503 |
| Riegler J et al. | Blue shift of CdSe/ZnS nanocrystal-labels upon DNA-hybridization. | 2008 | J Nanobiotechnology | pmid:18489732 |
| Simon MN et al. | Persistent activation of Akt or ERK prevents the toxicity induced by saturated and polyunsaturated fatty acids in RINm5F β-cells. | 2008 | Toxicol In Vitro | pmid:18395405 |
| Arida AI and Al-Tabakha MM | Cellactose a co-processed excipient: a comparison study. | 2008 | Pharm Dev Technol | pmid:18379907 |
| Ranji A et al. | Determination of calcium stearate in polyolefin samples by gas chromatographic technique after performing dispersive liquid-liquid microextraction. | 2008 | Anal Sci | pmid:18469468 |
| Jones PJ | Dietary agents that target gastrointestinal and hepatic handling of bile acids and cholesterol. | 2008 | J Clin Lipidol | pmid:21291720 |
| Shah RB et al. | Comparative evaluation of flow for pharmaceutical powders and granules. | 2008 | AAPS PharmSciTech | pmid:18446489 |
| Lee YH et al. | Separation and determination of polyethylene glycol fatty acid esters in cosmetics by a reversed-phase HPLC/ELSD. | 2008 | Talanta | pmid:18371826 |
| Darole PS et al. | Formulation and evaluation of microemulsion based delivery system for amphotericin B. | 2008 | AAPS PharmSciTech | pmid:18446472 |
| Flasiński M et al. | Per-6-O-(tert-butyldimethylsilyl)cyclodextrins (TBDMS-CDs) in Langmuir monolayers: the importance of a spreading solvent in the preparation of LB layers suitable for sensor application. | 2008 | J Phys Chem B | pmid:18358030 |
| Liao KS et al. | Superhydrophobic surfaces formed using layer-by-layer self-assembly with aminated multiwall carbon nanotubes. | 2008 | Langmuir | pmid:18324860 |
| Lee DY and Fiehn O | High quality metabolomic data for Chlamydomonas reinhardtii. | 2008 | Plant Methods | pmid:18442406 |
| Gouda AA and Hassan WS | Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations. | 2008 | Chem Cent J | pmid:18410679 |
| Hu FQ et al. | Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin. | 2008 | Eur J Pharm Biopharm | pmid:17997293 |
| Vögler O et al. | Structure-effect relation of C18 long-chain fatty acids in the reduction of body weight in rats. | 2008 | Int J Obes (Lond) | pmid:18059405 |
| Jose R et al. | Dependence of luminescence efficiency of cdse quantum dots on chemical environments. | 2008 | J Nanosci Nanotechnol | pmid:19198279 |
| Ruths M et al. | Friction of fatty acids in nanometer-sized contacts of different adhesive strength. | 2008 | Langmuir | pmid:18085802 |
| Harding L et al. | The development of microthermal analysis and photothermal microspectroscopy as novel approaches to drug-excipient compatibility studies. | 2008 | Int J Pharm | pmid:18162342 |
| Desai D et al. | Solid-state interaction of stearic acid with povidone and its effect on dissolution stability of capsules. | 2008 | Int J Pharm | pmid:18194844 |
| Garay AS and Rodrigues DE | Effects of the inclusion of the spin label 10-doxyl-stearic acid on the structure and dynamics of model bilayers in water: stearic acid and stearic acid/cholesterol (50:20). | 2008 | J Phys Chem B | pmid:18198858 |
| Bacher C et al. | Granule fraction inhomogeneity of calcium carbonate/sorbitol in roller compacted granules. | 2008 | Int J Pharm | pmid:17765416 |
| Piao ZZ et al. | Colonic release and reduced intestinal tissue damage of coated tablets containing naproxen inclusion complex. | 2008 | Int J Pharm | pmid:17928177 |
| Jones OA et al. | A metabolomics based approach to assessing the toxicity of the polyaromatic hydrocarbon pyrene to the earthworm Lumbricus rubellus. | 2008 | Chemosphere | pmid:17928029 |
| Rhee YS et al. | Application of instrumental evaluation of color for the pre-formulation and formulation of rabeprazole. | 2008 | Int J Pharm | pmid:17919858 |
| Vehring R | Pharmaceutical particle engineering via spray drying. | 2008 | Pharm. Res. | pmid:18040761 |
| Wu H et al. | Process analytical technology (PAT): quantification approaches in terahertz spectroscopy for pharmaceutical application. | 2008 | J Pharm Sci | pmid:17722101 |
| Nyblom HK et al. | Glucose-induced de novo synthesis of fatty acyls causes proportional increases in INS-1E cellular lipids. | 2008 | NMR Biomed | pmid:17691080 |
| Werle M | Natural and synthetic polymers as inhibitors of drug efflux pumps. | 2008 | Pharm. Res. | pmid:17896100 |
| Hernández ML et al. | The utilization and desaturation of oleate and linoleate during glycerolipid biosynthesis in olive (Olea europaea L.) callus cultures. | 2008 | J. Exp. Bot. | pmid:18515829 |
| Fang YP et al. | Physicochemical and safety evaluation of 5-aminolevulinic acid in novel liposomes as carrier for skin delivery. | 2008 | J Liposome Res | pmid:18348070 |
| Dou M et al. | [Orthogonal experiments for optimizing the formulation and preparation conditions of temozolomide solid lipid nanoparticles]. | 2008 | Sheng Wu Yi Xue Gong Cheng Xue Za Zhi | pmid:19024463 |
| Vartorelli MR et al. | Spin-labeled stearic acid behavior and perturbations on the structure of a gel-phase-lipid bilayer in water: 5-, 12- and 16-SASL. | 2008 | J Phys Chem B | pmid:19055388 |
| Lasserre R et al. | Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation. | 2008 | Nat. Chem. Biol. | pmid:18641634 |
| Aoki PH et al. | Sensor array made with nanostructured films to detect a phenothiazine compound. | 2008 | J Nanosci Nanotechnol | pmid:19049023 |
| Zhang JX et al. | Sex- and gonad-affecting scent compounds and 3 male pheromones in the rat. | 2008 | Chem. Senses | pmid:18515819 |
| Kirtsreesakul V et al. | Microbiology and antimicrobial susceptibility patterns of commensal flora in the middle nasal meatus. | 2008 | Ann. Otol. Rhinol. Laryngol. | pmid:19140538 |
| McNamara RK et al. | Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder. | 2008 | Psychiatry Res | pmid:18715653 |
| Xu G and Fang Y | Studies of surface-enhanced Raman scattering of C60 Langmuir-Blodgett film on a new substrate. | 2008 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:17889595 |
| Chatterjee A and Chowdhury R | Bile and unsaturated fatty acids inhibit the binding of cholera toxin and Escherichia coli heat-labile enterotoxin to GM1 receptor. | 2008 | Antimicrob. Agents Chemother. | pmid:17954701 |
| Zeng Q et al. | Highly luminescent CdSe/ZnSe core-shell quantum dots of one-pot preparation in octadecene. | 2008 | J Nanosci Nanotechnol | pmid:18468151 |
| Karoussi O and Hamouda AA | Macroscopic and nanoscale study of wettability alteration of oil-wet calcite surface in presence of magnesium and sulfate ions. | 2008 | J Colloid Interface Sci | pmid:17931645 |
| Fujio J et al. | Regulation of gut-derived resistin-like molecule beta expression by nutrients. | 2008 | Diabetes Res. Clin. Pract. | pmid:17936398 |
| Asadi A et al. | Interaction of bovine serum albumin with some novel PEG-containing diblock copolymers. | 2008 | Int. J. Biol. Macromol. | pmid:18602419 |
| Miguélez-Morán AM et al. | The effect of lubrication on density distributions of roller compacted ribbons. | 2008 | Int J Pharm | pmid:18602976 |
| Wan F et al. | Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro. | 2008 | Int J Pharm | pmid:18450394 |
| Richardson AD et al. | Central carbon metabolism in the progression of mammary carcinoma. | 2008 | Breast Cancer Res. Treat. | pmid:17879159 |
| Kumon M et al. | Application and mechanism of inhalation profile improvement of DPI formulations by mechanofusion with magnesium stearate. | 2008 | Chem. Pharm. Bull. | pmid:18451547 |
| Zhang XG et al. | Reversal activity of nanostructured lipid carriers loading cytotoxic drug in multi-drug resistant cancer cells. | 2008 | Int J Pharm | pmid:18586075 |
| Gotoh K et al. | A quartz crystal microbalance simulation to examine the effect of ultraviolet light treatment on characteristics of polyethylene surface. | 2008 | J Oleo Sci | pmid:18685232 |
| Adeagbo AA and Alebiowu G | Evaluation of cocoa butter as potential lubricant for coprocessing in pharmaceutical tablets. | 2008 | Pharm Dev Technol | pmid:18484488 |
| Cai JY et al. | [Studies on chemical constituents from Anoectochilus roxburghii]. | 2008 | Zhong Yao Cai | pmid:18619237 |
| Ma BJ et al. | [Chemical constituents study on the fruiting bodies of Lactarius rufus]. | 2008 | Zhong Yao Cai | pmid:18619269 |
| Fini A et al. | Raman and thermal analysis of indomethacin/PVP solid dispersion enteric microparticles. | 2008 | Eur J Pharm Biopharm | pmid:18621516 |
| Liu LX et al. | Effect of particle properties on the flowability of ibuprofen powders. | 2008 | Int J Pharm | pmid:18652883 |
| Ling XY et al. | Supramolecular layer-by-layer assembly of 3D multicomponent nanostructures via multivalent molecular recognition. | 2008 | Int J Mol Sci | pmid:19325764 |
| Aleong JM et al. | Ice recrystallization inhibition in ice cream by propylene glycol monostearate. | 2008 | J. Food Sci. | pmid:19021802 |
| Li Y and Weng W | Surface modification of hydroxyapatite by stearic acid: characterization and in vitro behaviors. | 2008 | J Mater Sci Mater Med | pmid:17569011 |
| Mazumder B et al. | Flow of Formulation Granules through a Conical Hopper. | 2008 | Indian J Pharm Sci | pmid:21369452 |
| Shah DA et al. | Stability Indicating RP-HPLC Estimation of Atorvastatin Calcium and Amlodipine Besylate in Pharmaceutical Formulations. | 2008 | Indian J Pharm Sci | pmid:21369436 |