MeSH term | MeSH ID | Detail |
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Obesity, Abdominal | D056128 | 3 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kushner J and Schlack H | Commercial scale validation of a process scale-up model for lubricant blending of pharmaceutical powders. | 2014 | Int J Pharm | pmid:25152166 |
Mateo-Ortiz D et al. | Analysis of powder phenomena inside a Fette 3090 feed frame using in-line NIR spectroscopy. | 2014 | J Pharm Biomed Anal | pmid:25128874 |
Horio T et al. | Effect of particle shape on powder flowability of microcrystalline cellulose as determined using the vibration shear tube method. | 2014 | Int J Pharm | pmid:25079435 |
Yodkhum K and Phaechamud T | Hydrophobic chitosan sponges modified by aluminum monostearate and dehydrothermal treatment as sustained drug delivery system. | 2014 | Mater Sci Eng C Mater Biol Appl | pmid:25063173 |
Pavićević ID et al. | Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal. | 2014 | Chem. Biol. Interact. | pmid:25451573 |
DÃaz R et al. | Identification of fatty acids in canine seminal plasma. | 2014 | Andrologia | pmid:23398451 |
Eiras CE et al. | Glycerine levels in the diets of crossbred bulls finished in feedlot: carcass characteristics and meat quality. | 2014 | Meat Sci. | pmid:24211551 |
Sertoglu E et al. | Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus. | 2014 | Chem. Phys. Lipids | pmid:24384240 |
Khodadoust S et al. | Identification and determination of the fatty acid composition of Quercus brantii growing in southwestern Iran by GC-MS. | 2014 | Nat. Prod. Res. | pmid:24499169 |
Wu MH et al. | A novel sodium N-fatty acyl amino acid surfactant using silkworm pupae as stock material. | 2014 | Sci Rep | pmid:24651079 |