MeSH term | MeSH ID | Detail |
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Decalcification, Pathologic | D003649 | 1 associated lipids |
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with stearic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kottala N et al. | Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. | 2012 | AAPS PharmSciTech | pmid:22965660 |
Casiraghi A et al. | The influence of the polar head and the hydrophobic chain on the skin penetration enhancement effect of poly(ethylene glycol) derivatives. | 2012 | AAPS PharmSciTech | pmid:22232021 |
Morkhade DM et al. | PEGylated rosin derivatives: novel microencapsulating materials for sustained drug delivery. | 2007 | AAPS PharmSciTech | pmid:17622122 |
Navaneethan CV et al. | Application of powder rheometer to determine powder flow properties and lubrication efficiency of pharmaceutical particulate systems. | 2005 | AAPS PharmSciTech | pmid:16353997 |
Soares LA et al. | Dry granulation and compression of spray-dried plant extracts. | 2005 | AAPS PharmSciTech | pmid:16353993 |
Tatavarti AS et al. | Assessment of NIR spectroscopy for nondestructive analysis of physical and chemical attributes of sulfamethazine bolus dosage forms. | 2005 | AAPS PharmSciTech | pmid:16353969 |
Nokhodchi A et al. | Cogrinding as a tool to produce sustained release behavior for theophylline particles containing magnesium stearate. | 2009 | AAPS PharmSciTech | pmid:19862623 |
Seitavuopio P et al. | Monitoring tablet surface roughness during the film coating process. | 2006 | AAPS PharmSciTech | pmid:16796349 |
Salbu L et al. | Direct compression behavior of low- and high-methoxylated pectins. | 2010 | AAPS PharmSciTech | pmid:20013080 |
Thotakura N et al. | Chitosan-Stearic Acid Based Polymeric Micelles for the Effective Delivery of Tamoxifen: Cytotoxic and Pharmacokinetic Evaluation. | 2017 | AAPS PharmSciTech | pmid:27287243 |