stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Edema D004487 152 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypothyroidism D007037 32 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
BERGELSON LD et al. COMPLETE STRUCTURAL ANALYSIS OF FATTY ACID MIXTURES BY THIN-LAYER CHROMATOGRAPHY. 1964 J. Chromatogr. pmid:14205937
ROWE CE THE OCCURRENCE AND METABOLISM IN VITRO OF UNESTERIFIED FATTY ACID IN MOUSE BRAIN. 1964 Biochim. Biophys. Acta pmid:14230816
KELLERMAN GM and JOLLOW DJ CONVERSION OF STEARIC ACID INTO OLEIC ACID IN ADIPOSE TISSUE. 1964 Biochim. Biophys. Acta pmid:14230826
BRYAN GT et al. IN VIVO ELUTION OF TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS FROM CHOLESTEROL PELLETS IMPLANTED INTO MOUSE BLADDERS. 1964 Cancer Res. pmid:14188460
KAKEMI K et al. [STUDIES ON SUCROSE ESTERS. 3. EFFECT OF SUCROSE ESTERS ON THE ABSORPTION OF DRUGS FROM THE ALIMENTARY TRACT]. 1964 Yakugaku Zasshi pmid:14266554
PREISS B and BLOCH K OMEGA-OXIDATION OF LONG CHAIN FATTY ACIDS IN RAT LIVER. 1964 J. Biol. Chem. pmid:14114877
KRITCHEVSKY D EXPERIMENTAL ATHEROSCLEROSIS IN RABBITS FED CHOLESTEROL-FREE DIETS. 1964 Jan-Feb J Atheroscler Res pmid:14112225
MAKLEIT JK et al. THIN LAYER AND GAS CHROMATOGRAPHIC ANALYSIS OF SYPHILIS ANTIGENS. 1964-1965 Acta Microbiol Acad Sci Hung pmid:14314670
TINOCO J et al. LIVER LIPIDS OF CHOLINE-DEFICIENT RATS. 1965 Biochem. J. pmid:14345885
FOX AM ABSORPTION OF FATTY ACIDS BY ISOLATED SEGMENTS OF TURTLE SMALL INTESTINE. 1965 Comp. Biochem. Physiol. pmid:14327569
HANSEN IA SELECTIVE INCORPORATION OF FATTY ACIDS INTO LIPIDS OF LAMB AND RAT INTESTINAL MUCOSA. 1965 Comp. Biochem. Physiol. pmid:14348000
NEWLAND J et al. PHOSPHORUS METABOLISM IN VIRAL-INDUCED NEOPLASIA. II. IN VIVO AND IN VITRO STUDIES OF THE MILK AND MAMMARY GLAND LIPIDES OF STRAINS OF MICE SUSCEPTIBLE TO THE MAMMARY TUMOR VIRUS. 1965 Can. J. Biochem. pmid:14329900
NOBLE RC and MOORE JH FURTHER STUDIES ON THE LIPID METABOLISM OF THE NORMAL AND VITAMIN B-12 DEFICIENT CHICK EMBRYO. 1965 Biochem. J. pmid:14333549
WINTER CA and FLATAKER L NOCICEPTIVE THRESHOLDS AS AFFECTED BY PARENTERAL ADMINISTRATION OF IRRITANTS AND OF VARIOUS ANTINOCICEPTIVE DRUGS. 1965 J. Pharmacol. Exp. Ther. pmid:14334273
DICOSTANZO G and CLEMENT J ["IN VIVO" INCORPORATION OF TRITIATED OLEIC, STEARIC AND PALMITIC ACIDS INTO LIPIDS OF RAT INTESTINAL LUMEN AND MUCOSA. IMPORTANCE OF SUPPLY OF ENDOGENOUS FATTY ACIDS]. 1965 Bull. Soc. Chim. Biol. pmid:14334811
SRIDHARA S and BHAT JV FURTHER INVESTIGATIONS OF THE INCORPORATION OF (1-14C)ACETATE INTO THE LIPIDS OF THE SILKWORM BOMBYX MORI L. 1965 Biochem. J. pmid:14340061
BOUCROT P and CLEMENT J [SUPPLY OF ENDOGENOUS FATTY ACIDS IN RAT LYMPH FOLLOWING ADMINISTRATION OF A MEAL CONTAINING MIXED C14-STEARIC: H3-OLEIC TRIGLYCERIDES]. 1965 C. R. Hebd. Seances Acad. Sci. pmid:14341956
ROOTS BI and JOHNSTON PV LIPIDS OF ISOLATED NEURONS. 1965 Biochem. J. pmid:14342249
KANFER J OBSERVATIONS ON CEREBROSIDE METABOLISM IN VIVO. 1965 J. Biol. Chem. pmid:14275111
KEITEL HG and CHU E PREMATURE INFANT FEEDING. I. THE CLINICAL USEFULNESS OF CALORIC CONCENTRATION OF FORMULAS, OF EARLY VERSUS LATE FEEDINGS AND OF LOW STEARIC ACID CONTENT FORMULAS. 1965 Pediatr. Clin. North Am. pmid:14276882