stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Edema D004487 152 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypothyroidism D007037 32 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Porra RJ and Stumpf PK Lipid biosynthesis in developing and germinating soybean cotyledons. The formation of palmitate and stearate by chopped tissue and supernatant preparations. 1976 Arch. Biochem. Biophys. pmid:987755
Weber J et al. [Can zinc stearate cause lung fibrosis? (Case report)]. 1976 Beitr Silikoseforsch Pneumokoniose pmid:990095
Yamashita T et al. [Studies on erythromycin stearate capsules (OE-7) (author's transl)]. 1976 Jpn J Antibiot pmid:933342
Thies C Development of injectable microcapsules for use in the treatment of narcotic addiction. 1976 Natl Inst Drug Abuse Res Monogr Ser pmid:967230
Gray AP and Guardina WJ Long-acting narcotic antagonist complexes. 1976 Natl Inst Drug Abuse Res Monogr Ser pmid:967231
Eliasz AW et al. Phospholipid phase transitions. Effects of n-alcohols, n-monocarboxylic acids, phenylalkyl alcohols and quaternary ammonium compounds. 1976 Biochim. Biophys. Acta pmid:971432
Graham KC et al. Simple thin-layer chromatographic identification method for erythromycin stearate. 1976 J. Chromatogr. pmid:977688
Matsuda Y et al. Comparative evaluation of tablet lubricants: effect of application method on tablet hardness and ejectability after compression. 1976 J Pharm Sci pmid:978434
Caster WO et al. Effect of dietary palmitate, stearate, oleate and linoleate on the tissue lipid and systolic blood pressure of the rat. 1976 Int J Vitam Nutr Res pmid:1010686
Brown ST Treatment of secondary syphilis. 1976 J Am Vener Dis Assoc pmid:1010778
Norwitz G and Galan M Determination of barium and strontium peroxides (active oxygen) in igniters in small-arms tracer ammunition. 1976 Talanta pmid:18961958
Boggiano BG and Gleeson M Gastric acid inactivation of erythromycin stearate in solid dosage forms. 1976 J Pharm Sci pmid:5588
Ahmed M and Enever RP Influence of magnesium stearate on the dissolution and biological availability of sulphadiazine tablet formulations [proceedings]. 1976 J. Pharm. Pharmacol. pmid:12326
Soler-Argilaga C et al. The effect of sex on the quantity and properties of the very low density lipoprotein secreted by the liver in vitro. 1976 J. Lipid Res. pmid:178815
Uyesaka N et al. Lanthanum and some other cation-induced changes in fluidity of synaptosomal membrane studied with nitroxide stearate spin labels. 1976 J. Membr. Biol. pmid:181579
Miller RW and De La Roche IA Properties of spin labelled membranes of Fusarium oxysporum f. sp. lycopersici. 1976 Biochim. Biophys. Acta pmid:182261
Ruf HH and Gratzl M Binding of nitroxide stearate spin labels to bovine serum albumin. 1976 Biochim. Biophys. Acta pmid:184832
Todorow S and Elies W [Oily contrast medium in liquor space following myelography. A clinical-radiological study on extent, velocity and ways of elimination of monoiodine stearate]. 1976 Neurochirurgia (Stuttg) pmid:185538
Marai L et al. Identification of isomeric doxyl stearic acids by gas-liquid chromatography and mass spectrometry. 1976 Chem. Phys. Lipids pmid:186203
Zenser TV et al. Spin-labeled stearates as probes for microenvironment of murine thymocyte adenylate cyclase-cyclic adenosine 3':5'-monophosphate system. 1976 J. Biol. Chem. pmid:187588