stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Edema D004487 152 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypothyroidism D007037 32 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Chung DJ et al. Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. 2007 Yonsei Med. J. pmid:17461529
Hatipoglu ON and Tasan Y A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. 2000 Yonsei Med. J. pmid:10957888
Chen JM et al. [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. 2009 Ying Yong Sheng Tai Xue Bao pmid:20353052
Bai YJ et al. [Structure identification of jujuboside E]. 2003 Yao Xue Xue Bao pmid:15040089
Chen DB et al. [In vitro and in vivo study of two kinds of long-circulating solid lipid nanoparticles containing paclitaxel]. 2002 Yao Xue Xue Bao pmid:12579901
Ye YQ et al. [Preparation and characterization of stearic acid-grafted chitosan oligosaccharide polymeric micelles]. 2004 Yao Xue Xue Bao pmid:15491108
Li CC et al. [In situ rat intestine absorption of paclitaxel-loaded solid lipid nanoparticles modified with cell-penetrating peptides]. 2013 Yao Xue Xue Bao pmid:23600154
Jiang RG et al. [Effect of surface modification on surface energy of lactose and performance of dry powder inhalations]. 2005 Yao Xue Xue Bao pmid:16011271
NAKAGAKI M and NISHINO M [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF ALUMINUM SOAPS. III. COMPOSITION OF ALUMINUM STEARATE AND STRUCTURAL VISCOSITY OF BENZENE SOLUTION]. 1963 Yakugaku Zasshi pmid:14094211
NAKAGAKI M and NISHINO M [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF ALUMINUM SOAPS. IV. EFFECT OF THERMAL TREATMENT ON THE STRUCTURE OF THE SOAP]. 1963 Yakugaku Zasshi pmid:14094212
Sunagane N et al. [Possibility of interactions between prescription drugs and OTC drugs (2nd report)--interaction between levodopa preparation and OTC Kampo medicines for upset stomach]. 2006 Yakugaku Zasshi pmid:17077621
Goto S et al. [Effect of magnesium stearate in preparation of eudragit RS-microcapsules containing drugs]. 1985 Yakugaku Zasshi pmid:3835255
Nakagawa H et al. [Effects of particle size of rifampicin and addition of magnesium stearate on release of rifampicin from hard gelatin capsules (author's transl)]. 1980 Yakugaku Zasshi pmid:7205556
Nadai M et al. [Correlation between in vitro dissolution characteristics of macrolide antibiotic tablets and bioavailability in man]. 1987 Yakugaku Zasshi pmid:3437396
NAKAGAKI M and NISHINO M [Studies on the physicochemical properties of aluminum soap. II. Structural viscosity of aluminum stearate in benzene]. 1963 Yakugaku Zasshi pmid:13937343
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. 3. Influence of calcium stearate content on compacting phenomenon of pharmaceutical powders (author's transl)]. 1973 Yakugaku Zasshi pmid:4797567
Miyake Y et al. [Studies on packing-property of pharmaceutical powders. II. Compacting phenomenon of pharmaceutical powders in the course of mixing with calcium stearate]. 1972 Yakugaku Zasshi pmid:4675495
NISHINO M [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF ALUMINUM SOAPS. V. STRUCTURAL VISCOSITY OF ALUMINUM STEARATES IN VEGETABLE OILS]. 1964 Yakugaku Zasshi pmid:14266543
NAKAGAKI M and NISHINO M [STUDIES ON THE PHYSICO-CHEMICAL PROPERTIES OF ALUMINUM SOAPS. VI. EFFECT OF ADDITIVES ON THE VISCOSITY OF BENZENE SOLUTION OF ALUMINUM DISTEARATE]. 1964 Yakugaku Zasshi pmid:14266544
KAKEMI K et al. [STUDIES ON SUCROSE ESTERS. 3. EFFECT OF SUCROSE ESTERS ON THE ABSORPTION OF DRUGS FROM THE ALIMENTARY TRACT]. 1964 Yakugaku Zasshi pmid:14266554