stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Edema D004487 152 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypothyroidism D007037 32 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Foudin L et al. Ethanol consumption and serum lipid profiles in Sinclair(S-1) miniature swine. 1984 Life Sci. pmid:6700380
Sakaguchi M et al. Effect of dietary unsaturated and saturated fats on azoxymethane-induced colon carcinogenesis in rats. 1984 Cancer Res. pmid:6704963
Anderson R et al. Studies on the effects of ingestion of a single 500 mg oral dose of erythromycin stearate on leucocyte motility and transformation and on release in vitro of prostaglandin E2 by stimulated leucocytes. 1984 J. Antimicrob. Chemother. pmid:6592163
Romanowski B and Grace M Non-gonococcal urethritis: a comparison of therapy with minicycline, tetracycline and erthromycin. 1984 Can Fam Physician pmid:21278971
Pediconi MF and Rodríguez de Turco EB Free fatty acid content and release kinetics as manifestations of cerebral lateralization in mouse brain. 1984 J. Neurochem. pmid:6726237
Aylsworth CF et al. Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication. 1984 J. Natl. Cancer Inst. pmid:6422115
Kido H et al. Inhibition of chymase activity by long chain fatty acids. 1984 Arch. Biochem. Biophys. pmid:6424574
Feix JB et al. An electron-electron double-resonance study of interactions between [14N]- and [15N]stearic acid spin-label pairs: lateral diffusion and vertical fluctuations in dimyristoylphosphatidylcholine. 1984 Biochemistry pmid:6329270
Lem NW and Stumpf PK In Vitro Fatty Acid Synthesis and Complex Lipid Metabolism in the Cyanobacterium, Anabaena Variabilis: II. Acyl Transfer and Complex Lipid Formation. 1984 Plant Physiol. pmid:16663690
Francis H et al. Severe vascular spasm due to erythromycin-ergotamine interaction. 1984 Clin. Rheumatol. pmid:6236021
Bhakoo KK et al. Regional studies of changes in brain fatty acids following experimental ischaemia and reperfusion in the gerbil. 1984 J. Neurochem. pmid:6236282
Abumrad NA et al. Permeation of long-chain fatty acid into adipocytes. Kinetics, specificity, and evidence for involvement of a membrane protein. 1984 J. Biol. Chem. pmid:6746632
Bridges CD et al. Visual cycle in the mammalian eye. Retinoid-binding proteins and the distribution of 11-cis retinoids. 1984 Vision Res. pmid:6543481
Fenyvest E et al. Cyclodextrin polymer, a new tablet disintegrating agent. 1984 Pharmazie pmid:6494226
Junginger H [The ratio of free and fixed interlamellar water as quality criteria for O/W creams]. 1984 Pharmazie pmid:6504995
Kennett FF et al. Inhibition of myocardial rotenone-insensitive NADH cytochrome c reductase by amphiphilic compounds. 1984 Am. J. Physiol. pmid:6507637
Wirthensohn G et al. Phospholipid metabolism in rat kidney cortical tubules. I. Effect of renal substrates. 1984 Biochim. Biophys. Acta pmid:6477951
Shechter Y and Henis YI Cis-unsaturated fatty acids induce both lipogenesis and calcium binding in adipocytes. 1984 Biochim. Biophys. Acta pmid:6477975
Bogdanov AA et al. Immobilization of alpha-chymotrypsin on sucrose stearate--palmitate containing liposomes. 1984 FEBS Lett. pmid:6479332
Junginger HE Colloidal structures of O/W creams. 1984 Pharm Weekbl Sci pmid:6483570
Mogelson S and Lange LG Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase. 1984 Biochemistry pmid:6487591
Boakes AJ et al. Treatment of uncomplicated gonorrhoea in women with a combination of rifampicin and erythromycin. 1984 Br J Vener Dis pmid:6487986
Fernandes AC et al. Enhancement of human polymorphonuclear leucocyte motility by erythromycin in vitro and in vivo. 1984 S. Afr. Med. J. pmid:6463793
Yoshida S and Takeshita M Arachidoyl- and arachidonoyl-CoA elongation mechanism in swine cerebral microsomes. 1984 Biochim. Biophys. Acta pmid:6466693
Waldman SA et al. Acyl composition and phospholipase activities in plasma membranes isolated from rat embryos. 1984 Int. J. Biochem. pmid:6468725
Slevin ML et al. The pharmacokinetics of subcutaneous bolus cytosine arabinoside in an arachis oil plus aluminium distearate suspension. 1984 Invest New Drugs pmid:6511233
Rosén C et al. Acute otitis media in older children and adults treated with phenoxymethyl penicillin or erythromycin stearate. Bacteriological and immunological aspects. 1983 Sep-Oct Acta Otolaryngol. pmid:6416018
Robson HG et al. Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis. 1983 Jul-Sep Sex Transm Dis pmid:6648747
Hashisaki P et al. Erythromycin failure in the treatment of syphilis in a pregnant woman. 1983 Jan-Mar Sex Transm Dis pmid:6601848
Rosenthal MD and Whitehurst MC Selective effects of isomeric cis and trans fatty acids on fatty acyl delta 9 and delta 6 desaturation by human skin fibroblasts. 1983 Biochim. Biophys. Acta pmid:6615875
Hwang CC and Danti AG Percutaneous absorption of flufenamic acid in rabbits: effect of dimethyl sulfoxide and various nonionic surface-active agents. 1983 J Pharm Sci pmid:6620136
Philip J and Daly RE Test for selection of erythromycin stearate bulk drug for tablet preparation. 1983 J Pharm Sci pmid:6620167
Shih JC and Ohsawa R Differential effect of cholesterol on two types of 5-hydroxytryptamine binding sites. 1983 Neurochem. Res. pmid:6621769
van Kamp HV et al. Improvement by super disintegrants of the properties of tablets containing lactose, prepared by wet granulation. 1983 Pharm Weekbl Sci pmid:6622211
Erman A et al. Phospholipase A2 inhibitors. Differential inhibition of fatty acid acylation into kidney lipids by mepacrine and p-bromophenacyl bromide. 1983 Biochem. Pharmacol. pmid:6870935
Flood MT et al. Vitamin A utilization in human retinal pigment epithelial cells in vitro. 1983 Invest. Ophthalmol. Vis. Sci. pmid:6885309
Chien JL and Hogan EL Novel pentahexosyl ganglioside of the globo series purified from chicken muscle. 1983 J. Biol. Chem. pmid:6885798
Foot M et al. Some properties, including the substrate in vivo, of the delta 9-desaturase in Micrococcus cryophilus. 1983 Biochem. J. pmid:6847622
Quinn PA et al. Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. 1983 Am. J. Obstet. Gynecol. pmid:6849358
Streichman S et al. Unique profile for erythrocyte membrane acetylcholinesterase in hereditary spherocytosis. 1983 Biochim. Biophys. Acta pmid:6849970
Sobel JD et al. Legionella bozemanii. Still another cause of pneumonia. 1983 JAMA pmid:6854903
Stults BM et al. Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease. 1983 South. Med. J. pmid:6857302
Slomiany A et al. Isolation of fatty acids covalently bound to the gastric mucus glycoprotein of normal and cystic fibrosis patients. 1983 Biochem. Biophys. Res. Commun. pmid:6860340
Slomiany A et al. Covalently linked fatty acids in gastric mucus glycoprotein of cystic fibrosis patients. 1983 J. Biol. Chem. pmid:6863300
Khan KA et al. The effect of mixing time of magnesium stearate on the tableting properties of dried microcrystalline cellulose. 1983 Pharm Acta Helv pmid:6867042
Shanson DC et al. High dose oral erythromycin for preventing endocarditis. 1983 Lancet pmid:6130318
Carli F and Colombo I Influence of porosity on the contact angle of non-wet solids. 1983 J. Pharm. Pharmacol. pmid:6135790
Gabriel SM and Simpkins JW Effects of a sustained-release naloxone pellet on luteinizing hormone secretion in female rats. 1983 Neuroendocrinology pmid:6139759
Agrawal HC et al. In vivo incorporation of [3H]palmitic acid into PO protein, the major intrinsic protein of rat sciatic nerve myelin. 1983 J. Biol. Chem. pmid:6189827
Neufeld EJ et al. High affinity esterification of eicosanoid precursor fatty acids by platelets. 1983 J. Clin. Invest. pmid:6308046