| MeSH term | MeSH ID | Detail |
|---|---|---|
| Edema | D004487 | 152 associated lipids |
| Leukodystrophy, Metachromatic | D007966 | 4 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Hypothyroidism | D007037 | 32 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Hypersensitivity, Delayed | D006968 | 43 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bolhuis GK et al. | Interaction of tablet disintegrants and magnesium stearate during mixing I: Effect on tablet disintegration. | 1981 | J Pharm Sci | pmid:7320846 |
| Loi F and Amati R | [Lead-stearate exposure in a plastic factory in the province of Siena (author's transl)]. | 1981 Sep-Oct | Med Lav | pmid:7322018 |
| Cook HW | The influence of trans-acids on desaturation and elongation of fatty acids in developing brain. | 1981 | Lipids | pmid:7329212 |
| Yue KT et al. | Effect of glucose on plasma concentrations of individual non-esterified fatty acids of non-diabetic and insulin-independent diabetic men. | 1981 | Postgrad Med J | pmid:7335561 |
| Sugita M et al. | Studies on glycosphingolipids of fresh-water bivalves. VI. Isolation and chemical characterization of neutral glycosphingolipids from spermatozoa of the fresh-water bivalve, Hyriopsis schlegelii. | 1981 | J. Biochem. | pmid:7338520 |
| Haley K et al. | Optimal milk penicillin levels for the treatment of experimentally induced mastitis in cows. | 1981 | Can. J. Comp. Med. | pmid:7340909 |
| Branigan TA et al. | The effects of erythromycin on the absorption and disposition of kinetics of theophylline. | 1981 | Eur. J. Clin. Pharmacol. | pmid:7341279 |
| Morimoto K and Kanoh H | The role of the de novo synthetic pathway in forming molecular species of phospholipids in resting lymphocytes from human tonsils. | 1980 | Biochim. Biophys. Acta | pmid:7353023 |
| Shepherd J et al. | Effects of saturated and polyunsaturated fat diets on the chemical composition and metabolism of low density lipoproteins in man. | 1980 | J. Lipid Res. | pmid:7354257 |
| Wood R et al. | Effect of methyl 2-hexadecynoate on hepatic fatty acid metabolism. | 1980 | Lipids | pmid:7374364 |
| Herrmann H and Gercken G | Incorporation of [1-14C]octadecanol into the lipids of Leishmania donovani. | 1980 | Lipids | pmid:7374369 |
| Clarke CW et al. | A new formulation of erythromycin stearate: blood and sputum levels in patients with chronic lower respiratory tract infection. | 1980 | J. Antimicrob. Chemother. | pmid:7400071 |
| Matocha M and Wood R | Changes in host animal plasma lipids during hepatoma growth. | 1980 | Lipids | pmid:7401940 |
| Holub BJ et al. | Relative suitability of 1-palmitoyl and 1-stearoyl homologues of 1-acyl-sn-glycerylphosphorylcholine and different acyl donors for phosphatidylcholine synthesis via acyl-CoA:1-acyl-sn-glycero-3-phosphorylcholine acyltransferase in rat lung microsomes. | 1980 | Can. J. Biochem. | pmid:7407680 |
| Thompson SE et al. | Gonococcal tenosynovitis-dermatitis and septic arthritis. Intravenous penicillin vs oral erythromycin. | 1980 | JAMA | pmid:7411761 |
| Springolo V | [Bioavailability of formulations containing erythromycin base or stearate in soft enteric gelatin capsules]. | 1978 | Boll Chim Farm | pmid:743360 |
| Marlin GE et al. | Plasma and sputum erythromycin concentrations in chronic bronchitis. | 1980 | Thorax | pmid:7434299 |
| Søndergaard D et al. | Magnesium stearate given perorally to rats. A short term study. | 1980 | Toxicology | pmid:7434368 |
| Colmano G et al. | Activation of antibacterial silver coatings on surgical implants by direct current: preliminary studies in rabbits. | 1980 | Am. J. Vet. Res. | pmid:7436092 |
| Jaffe JH et al. | Abuse potential of loperamide. | 1980 | Clin. Pharmacol. Ther. | pmid:7438696 |
| Polnikorn N et al. | Penicillin concentrations in cerebrospinal fluid after different treatment regimens for syphilis. | 1980 | Br J Vener Dis | pmid:7448578 |
| Prescott SM and Majerus PW | The fatty acid composition of phosphatidylinositol from thrombin-stimulated human platelets. | 1981 | J. Biol. Chem. | pmid:7451460 |
| Stavchansky S et al. | Correlation of in vivo bioavailability of erythromycin stearate tablets with in vitro tests. | 1980 | J Pharm Sci | pmid:7452460 |
| Kaur R et al. | Comparison of polyethylene glycol and polyoxyethylene stearate as excipients for solid dispersion systems of griseofulvin and tolbutamide I: phase equilibria. | 1980 | J Pharm Sci | pmid:7452463 |
| Kaur R et al. | Comparison of polyethylene glycol and polyoxyethylene stearate as excipients for solid dispersion systems of griseofulvin and tolbutamide II: dissolution and solubility studies. | 1980 | J Pharm Sci | pmid:7452464 |
| Light ND and Bailey AJ | Polymeric C-terminal cross-linked material from type-I collagen. A modified method for purification, anomalous behaviour on gel filtration, molecular weight estimation, carbohydrate content and lipid content. | 1980 | Biochem. J. | pmid:7458897 |
| Ahmed M and Enever RP | The influence of magnesium stearate on physical properties and biological availability of sulphadiazine tablet formulations. | 1978 | Pharm Acta Helv | pmid:746045 |
| Cochran FB et al. | Myelin gangliosides: an unusual pattern in the avian central nervous system. | 1981 | J. Neurochem. | pmid:7463084 |
| Katan MB | Exit trans fatty acids. | 1995 | Lancet | pmid:7475713 |
| Tanaka H et al. | Morphology of a cytochrome c-adsorbed stearic acid monolayer on Brewster angle microscopy. | 1995 | J. Biochem. | pmid:7490253 |
| Cardoso CM and De Meis L | Modulation by fatty acids of Ca2+ fluxes in sarcoplasmic-reticulum vesicles. | 1993 | Biochem. J. | pmid:7504458 |
| Wang G et al. | Phosphatidylcholines with sn-1 saturated and sn-2 cis-monounsaturated acyl chains. Their melting behavior and structures. | 1995 | J. Biol. Chem. | pmid:7559399 |
| Tholstrup T et al. | Effect of fats high in individual saturated fatty acids on plasma lipoprotein[a] levels in young healthy men. | 1995 | J. Lipid Res. | pmid:7595068 |
| Torrado-Durán JJ et al. | Tableting characteristics of micro-aggregated egg albumin particles containing paracetamol. | 1995 | J. Pharm. Pharmacol. | pmid:7602464 |
| Mizushima H et al. | Thermotropic behavior of stratum corneum lipids containing a pseudo-ceramide. | 1995 | Lipids | pmid:7609600 |
| Sarel I and Widmaier EP | Stimulation of steroidogenesis in cultured rat adrenocortical cells by unsaturated fatty acids. | 1995 | Am. J. Physiol. | pmid:7611525 |
| Brewer E and Ramsland A | Particle size determination by automated microscopical imaging analysis with comparison to laser diffraction. | 1995 | J Pharm Sci | pmid:7629744 |
| Nonogaki T et al. | Developmental blockage of mouse embryos caused by fatty acids. | 1994 | J. Assist. Reprod. Genet. | pmid:7633171 |
| de la Casa E et al. | Effects of dietary oil related to the toxic oil syndrome on the lipids of guinea pig liver microsomes. | 1995 | Lipids | pmid:7651086 |
| Bizzozero OA | Chemical analysis of acylation sites and species. | 1995 | Meth. Enzymol. | pmid:7651165 |
| Canuto RA et al. | Changes of adenylate cyclase activity in AH-130 ascites hepatoma of Yoshida induced by enrichment with fatty acids. | 1995 | Biochem. Biophys. Res. Commun. | pmid:7654247 |
| Brink EJ et al. | Positional distribution of stearic acid and oleic acid in a triacylglycerol and dietary calcium concentration determines the apparent absorption of these fatty acids in rats. | 1995 | J. Nutr. | pmid:7666256 |
| van Tol A et al. | Dietary trans fatty acids increase serum cholesterylester transfer protein activity in man. | 1995 | Atherosclerosis | pmid:7669083 |
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| Bruce JS et al. | Desaturation and esterification of palmitic and stearic acids in cultured hepatocytes. | 1995 | Biochem. Soc. Trans. | pmid:7672331 |
| Zeng FY et al. | Fatty acylation of the rat asialoglycoprotein receptor. The three subunits from active receptors contain covalently bound palmitate and stearate. | 1995 | J. Biol. Chem. | pmid:7673174 |
| Fujimoto T et al. | P-selectin is acylated with palmitic acid and stearic acid at cysteine 766 through a thioester linkage. | 1993 | J. Biol. Chem. | pmid:7684381 |
| Keita Y et al. | Effect of free fatty acids on the binding kinetics at the benzodiazepine binding site of glycated human serum albumin. | 1993 | Int J Clin Pharmacol Ther Toxicol | pmid:7690351 |
| Robert S et al. | Fatty acid acylation of RNase A using reversed micelles as microreactors. | 1993 | Biochem. Biophys. Res. Commun. | pmid:7692851 |
| Dougherty RM et al. | Effects of diets containing high or low amounts of stearic acid on plasma lipoprotein fractions and fecal fatty acid excretion of men. | 1995 | Am. J. Clin. Nutr. | pmid:7733038 |