stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Edema D004487 152 associated lipids
Leukodystrophy, Metachromatic D007966 4 associated lipids
Coronary Disease D003327 70 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Acne Vulgaris D000152 35 associated lipids
Hypothyroidism D007037 32 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
STEIN O and STEIN Y METABOLISM OF FATTY ACIDS IN THE ISOLATED PERFUSED RAT HEART. 1963 Biochim. Biophys. Acta pmid:14085937
LEVY G and GUMTOW RH EFFECT OF CERTAIN TABLET FORMULATION FACTORS ON DISSOLUTION RATE OF THE ACTIVE INGREDIENT. III. TABLET LUBRICANTS. 1963 J Pharm Sci pmid:14088962
OSTWALD R Fat content and fatty acids in some commercial mixes for baked products. 1963 J Am Diet Assoc pmid:13940620
BLOMSTRAND R et al. BIOHYDROGENATION IN GERM-FREE RATS. 1963 Jul-Aug J Atheroscler Res pmid:14051792
ULLMANN E et al. [STUDIES ON THE STABILITY OF PENICILLIN G SODIUM IN THE PRESENCE OF IONOGENIC TENSIDES, ORGANIC GEL FORMERS AND PRESERVATIVE AGENTS. 7. COMMUNICATION ON THE INFLUENCE OF ADJUVANTS IN DRUG COMPOUNDING]. 1963 Jul-Aug Pharm Acta Helv pmid:14052353
LEFEBVRE P and HENRIOUL F [INFLUENCE OF GLUCAGON ON THE BLOOD LEVEL AND ARTERIO-VENOUS DIFFERENCE OF UNESTERIFIED FATTY ACIDS]. 1963 Sep-Oct Ann. Endocrinol. (Paris) pmid:14092350
GOODMAN DS et al. THE FORMATION OF CHOLESTEROL ESTERS WITH RAT LIVER ENZYMES. 1964 J. Biol. Chem. pmid:14189863
BILLOW BW et al. A CLINICAL STUDY OF ERYTHROMYCIN: A COMPARATIVE EVALUATION OF SEVERAL SALTS. 1964 Curr Ther Res Clin Exp pmid:14193771
ELOVSON J METABOLISM OF SOME MONOHYDROXYSTEARIC ACIDS IN THE INTACT RAT. 1964 Biochim. Biophys. Acta pmid:14194233
ENG LF et al. SEPARATION AND ISOLATION OF METHYL ESTERS AND DIMETHYLACETALS FORMED FROM BRAIN LIPIDS. 1964 J. Lipid Res. pmid:14173320
ACKMAN RG and BURGHER RD EMPLOYMENT OF ETHANOL AS A SOLVENT IN SMALL SCALE CATALYTIC HYDROGENATIONS OF METHYL ESTERS. 1964 J. Lipid Res. pmid:14173321
KATES M SIMPLIFIED PROCEDURES FOR HYDROLYSIS OR METHANOLYSIS OF LIPIDS. 1964 J. Lipid Res. pmid:14173322
VIVIANI R et al. FATTY ACID COMPOSITION OF PORTAL FATTY LIVER IN LYSINE- AND THREONINE-DEFICIENT RATS. 1964 J. Lipid Res. pmid:14173329
LANDS WE and HART P METABOLISM OF GLYCEROLIPIDS: V. METABOLISM OF PHOSPHATIDIC ACID. 1964 J. Lipid Res. pmid:14173334
DAUVILLIER P et al. [THE MODE OF ACTION OF PHOSPHOLIPASE A FROM SNAKE VENOM ON ELAIDIN SUBSTRATES]. 1964 C. R. Hebd. Seances Acad. Sci. pmid:14254951
DEGRELLE-CHEYMOL C [COMPARATIVE STUDY OF BLOOD LIPIDS IN THE HUMAN MOTHER AND FETUS AT TERM]. 1964 C. R. Hebd. Seances Acad. Sci. pmid:14254952
MURATA H [BIOCHEMICAL STUDIES ON PHYSIOLOGICAL UTILIZABILITY OF L-ASCORBYL STEARINE ESTER]. 1964 Tokyo Jikeikai Ika Daigaku Zasshi pmid:14288523
SOULA G et al. [DIFFUSION OF GLOBULAR FATTY ACIDS DURING OSMOTIC HEMOLYSIS]. 1964 Bull. Soc. Chim. Biol. pmid:14165549
GENTOU C [A MICRO-METHOD FOR EVALUATION OF SERUM "FREE FATTY ACIDS", UTILIZING THEIR SURFACE ACTIVITY]. 1964 Bull. Soc. Chim. Biol. pmid:14165551
BADINGS HT THIN-LAYER CHROMATOGRAPHY UNDER CONTROLLED CONDITIONS. 1964 J. Chromatogr. pmid:14165965