| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lymphadenitis | D008199 | 8 associated lipids |
| Liver Neoplasms | D008113 | 8 associated lipids |
| Leprosy | D007918 | 8 associated lipids |
| Mycobacterium Infections, Nontuberculous | D009165 | 8 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rideout TC et al. | Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice. | 2010 | Mol Nutr Food Res | pmid:20333723 |
| Zornetzer GA et al. | The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond. | 2010 | Biochemistry | pmid:20014832 |
| Even P et al. | Postprandial effects of a lipid-rich meal in the rat are modulated by the degree of unsaturation of 18C fatty acids. | 2010 | Metab. Clin. Exp. | pmid:19775712 |
| Hirabara SM et al. | Saturated fatty acid-induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells. | 2010 | J. Cell. Physiol. | pmid:19780047 |
| Lehto T et al. | Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. | 2010 | J Control Release | pmid:19744531 |
| Tay T et al. | Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism? | 2010 | Int J Pharm | pmid:19748561 |
| Almeida CP et al. | Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. | 2010 | Int J Nanomedicine | pmid:20957219 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Ram HN et al. | Formulation and evaluation of floating tablets of liquorice extract. | 2010 | Pharmacognosy Res | pmid:21589757 |
| Varshosaz J et al. | Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. | 2010 | Int J Prev Med | pmid:21566772 |
| Elbaz A et al. | Inhibition of fatty acid biosynthesis prevents adipocyte lipotoxicity on human osteoblasts in vitro. | 2010 | J. Cell. Mol. Med. | pmid:19382912 |
| Louis J et al. | PAD4-dependent antibiosis contributes to the ssi2-conferred hyper-resistance to the green peach aphid. | 2010 | Mol. Plant Microbe Interact. | pmid:20367470 |
| Ospina-E JC et al. | Development of combinations of chemically modified vegetable oils as pork backfat substitutes in sausages formulation. | 2010 | Meat Sci. | pmid:20374815 |
| Ye S et al. | Polyunsaturated docosahexaenoic acid suppresses oxidative stress induced endothelial cell calcium influx by altering lipid composition in membrane caveolar rafts. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20206488 |
| Rajab M et al. | Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid. | 2010 | Pharmazie | pmid:20225651 |
| Patel BP et al. | Formulation and evaluation of mouth dissolving tablets of cinnarizine. | 2010 | Indian J Pharm Sci | pmid:21218071 |
| Kotagale NR et al. | Carbopol 934-Sodium Alginate-Gelatin Mucoadhesive Ondansetron Tablets for Buccal Delivery: Effect of pH Modifiers. | 2010 | Indian J Pharm Sci | pmid:21218058 |
| Swami G et al. | Soyabean powder as a novel diluent in tablet formulation of simvastatin. | 2010 | Indian J Pharm Sci | pmid:21218051 |
| Balch RJ and Trescot A | Extended-release morphine sulfate in treatment of severe acute and chronic pain. | 2010 | J Pain Res | pmid:21197323 |
| El Hadrami A et al. | Chitosan in plant protection. | 2010 | Mar Drugs | pmid:20479963 |
| Mir VG et al. | Application of crustacean chitin as a co-diluent in direct compression of tablets. | 2010 | AAPS PharmSciTech | pmid:20238188 |
| Teixeira AC et al. | Phase behaviour of oleanolic acid, pure and mixed with stearic acid: Interactions and crystallinity. | 2010 | Chem. Phys. Lipids | pmid:20599856 |
| Borah BM et al. | Surface-modification-directed controlled adsorption of serum albumin onto magnetite nanocuboids synthesized in a gel-diffusion technique. | 2010 | J Colloid Interface Sci | pmid:20621808 |
| Zhu SH et al. | [Study on the chemical constituents of Dichrocephala integrifolia]. | 2010 | Zhong Yao Cai | pmid:20518304 |
| Manickam E et al. | Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. | 2010 | Lipids Health Dis | pmid:20525346 |
| Sateesha S et al. | Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. | 2010 | J Young Pharm | pmid:21042476 |
| Hurko O et al. | Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. | 2010 | Int J Alzheimers Dis | pmid:20981353 |
| A J et al. | Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses. | 2010 | PLoS ONE | pmid:20949032 |
| Thörn K et al. | Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells. | 2010 | Lipids Health Dis | pmid:20920255 |
| Aly S | Detachment and recovery index: A new parameter measuring powder compressibility. | 2010 | J Adv Pharm Technol Res | pmid:22247881 |
| Brown AW et al. | Plant sterol and stanol substrate specificity of pancreatic cholesterol esterase. | 2010 | J. Nutr. Biochem. | pmid:19615880 |
| Pires de Souza FC et al. | In vitro comparison of the radiopacity of cavity lining materials with human dental structures. | 2010 | J Conserv Dent | pmid:20859477 |
| Zhou YY et al. | Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin. | 2010 | Int J Pharm | pmid:20420886 |
| Wu T et al. | Study on superhydrophobic hybrids fabricated from multiwalled carbon nanotubes and stearic acid. | 2010 | J Colloid Interface Sci | pmid:20427047 |
| Tiemeyer S et al. | Effect of surface charge distribution on the adsorption orientation of proteins to lipid monolayers. | 2010 | Langmuir | pmid:20707324 |
| Barupal DK et al. | Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. | 2010 | BMC Biotechnol. | pmid:20492649 |
| Ye M et al. | Synthesis of Sb2E3 (E = S, Se) nanorods with a flat cross section by a rapid hot injection method. | 2010 | J Nanosci Nanotechnol | pmid:21138031 |
| Xu Y et al. | Carbon-covered magnetic nanomaterials and their application for the thermolysis of cancer cells. | 2010 | Int J Nanomedicine | pmid:20463932 |
| Prossnigg F et al. | Packing behaviour of two predominant anionic phospholipids of bacterial cytoplasmic membranes. | 2010 | Biophys. Chem. | pmid:20451316 |
| Chitapanarux I et al. | Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. | 2010 | Radiat Oncol | pmid:20444243 |
| Foster SP and Johnson CP | Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. | 2010 | J. Insect Physiol. | pmid:20540946 |
| Thörn K and Bergsten P | Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. | 2010 | J. Cell. Biochem. | pmid:20524206 |
| Zhou QT et al. | Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders. | 2010 | Eur J Pharm Sci | pmid:20433919 |
| Nokhodchi A et al. | Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives. | 2010 | Daru | pmid:22615598 |
| Croxton RS et al. | Variation in amino acid and lipid composition of latent fingerprints. | 2010 | Forensic Sci. Int. | pmid:20413233 |
| Milanovic J et al. | Microencapsulation of flavors in carnauba wax. | 2010 | Sensors (Basel) | pmid:22315575 |
| Shi X et al. | On the coating of precipitated calcium carbonate with stearic acid in aqueous medium. | 2010 | Langmuir | pmid:20334413 |
| Nagaich U et al. | Design and evaluation of a metronidazole central core matrix tablet. | 2010 | J Adv Pharm Technol Res | pmid:22247836 |
| Hsieh HT et al. | Facile synthesis of silver nanoparticles in CO2-expanded liquids from silver isostearate precursor. | 2010 | Langmuir | pmid:20297774 |
| Bhattacharya S and Nagaich U | Assessment of anti-nociceptive efficacy of costus speciosus rhizome in swiss albino mice. | 2010 | J Adv Pharm Technol Res | pmid:22247830 |
| Xing Z et al. | Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. | 2010 | Acta Biomater | pmid:20226284 |
| O'Byrne SM et al. | Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice. | 2010 | Am. J. Physiol. Endocrinol. Metab. | pmid:20040693 |
| Collins JM et al. | De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. | 2010 | J. Biol. Chem. | pmid:20032470 |
| Salbu L et al. | Direct compression behavior of low- and high-methoxylated pectins. | 2010 | AAPS PharmSciTech | pmid:20013080 |
| Zhang Y et al. | The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity. | 2010 | J. Lipid Res. | pmid:19609006 |
| Kuo WT et al. | Polymeric micelles comprising stearic acid-grafted polyethyleneimine as nonviral gene carriers. | 2010 | J Nanosci Nanotechnol | pmid:21133072 |
| Li YW et al. | [Studies on the chemical constituents of Ficus microcarpa]. | 2010 | Zhong Yao Cai | pmid:21049616 |
| Romanowicz L and Bańkowski E | Altered sphingolipid composition in Wharton's jelly of pre-eclamptic newborns. | 2010 | Pathobiology | pmid:20332667 |
| Zhang L et al. | Fabrication of nanotubules and microspheres from the self-assembly of amphiphilic monochain stearic acid derivatives. | 2010 | Langmuir | pmid:21049915 |
| Zarbakhsh A et al. | Stabilization of alkylated azacrown ether by fatty acid at the air-water interface. | 2010 | Langmuir | pmid:21049946 |
| Alshamsan A et al. | Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. | 2009 Jan-Feb | Mol. Pharm. | pmid:19053537 |
| Liu K et al. | Isolation and biochemical characterization of two lipases from a metagenomic library of China Holstein cow rumen. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19486892 |
| HÃ¥versen L et al. | Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. | 2009 | Atherosclerosis | pmid:18599066 |
| Yuan H et al. | Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles. | 2009 | Colloids Surf B Biointerfaces | pmid:19185474 |
| Cha D et al. | Analysis of fatty acids in sputum from patients with pulmonary tuberculosis using gas chromatography-mass spectrometry preceded by solid-phase microextraction and post-derivatization on the fiber. | 2009 | J Chromatogr A | pmid:19171347 |
| Mermigkis C et al. | A green oral appliance. | 2009 | Eur. Respir. J. | pmid:19181918 |
| Boros LG et al. | Ethanol diversely alters palmitate, stearate, and oleate metabolism in the liver and pancreas of rats using the deuterium oxide single tracer. | 2009 | Pancreas | pmid:19248221 |
| Ishitsuka Y et al. | Effects of bolus injection of soybean-based fat emulsion and fatty acids on pulmonary gas exchange function. | 2009 | Biol. Pharm. Bull. | pmid:19252304 |
| Pingali KC et al. | Use of a static eliminator to improve powder flow. | 2009 | Int J Pharm | pmid:19266628 |
| Shehab-El-Deen MA et al. | Cryotolerance of bovine blastocysts is affected by oocyte maturation in media containing palmitic or stearic acid. | 2009 | Reprod. Domest. Anim. | pmid:18992093 |
| Roberts LD et al. | Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse. | 2009 | Genome Med | pmid:19968882 |
| Oosterveer MH et al. | High fat feeding induces hepatic fatty acid elongation in mice. | 2009 | PLoS ONE | pmid:19557132 |
| Yamamura T et al. | Effects of automated external lubrication on tablet properties and the stability of eprazinone hydrochloride. | 2009 | Int J Pharm | pmid:19059327 |
| Plumley C et al. | Nifedipine nanoparticle agglomeration as a dry powder aerosol formulation strategy. | 2009 | Int J Pharm | pmid:19015016 |
| Burkhardt M et al. | Macroscopic properties and microstructure of HSA based organogels: sensitivity to polar additives. | 2009 | J Colloid Interface Sci | pmid:19144353 |
| Gohel M and Bariya SH | Advanced formulation design of venlafaxine hydrochloride coated and triple-layer tablets containing hypromellose. | 2009 | Pharm Dev Technol | pmid:19883254 |
| Chen CY et al. | Chemical constituents from the whole plant of Gaultheria itoana Hayata. | 2009 | Chem. Biodivers. | pmid:19842133 |
| Pingali KC et al. | Practical methods for improving flow properties of active pharmaceutical ingredients. | 2009 | Drug Dev Ind Pharm | pmid:19929205 |
| Herczeg M et al. | Toward synthesis of the isosteric sulfonate analogues of the AT-III binding domain of heparin. | 2009 | Org. Lett. | pmid:19473011 |
| Mattes RD | Oral thresholds and suprathreshold intensity ratings for free fatty acids on 3 tongue sites in humans: implications for transduction mechanisms. | 2009 | Chem. Senses | pmid:19357229 |
| Shen J et al. | Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery. | 2009 | J Control Release | pmid:19393270 |
| Swamy PV et al. | Preparation and evaluation of orodispersible tablets of pheniramine maleate by effervescent method. | 2009 | Indian J Pharm Sci | pmid:20336216 |
| Hanlon PR et al. | Aqueous extracts from dietary supplements influence the production of inflammatory cytokines in immortalized and primary T lymphocytes. | 2009 | BMC Complement Altern Med | pmid:20003431 |
| Teraoka R et al. | Effect of pharmaceutical excipients on the stability of trichlormethiazide tablets under humid conditions. | 2009 | Chem. Pharm. Bull. | pmid:19952441 |
| Hoppa MB et al. | Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules. | 2009 | Cell Metab. | pmid:19945403 |
| Weber K et al. | Lesions in the Larynx of Wistar RccHan: WIST Rats. | 2009 | J Toxicol Pathol | pmid:22271998 |
| Kalman DS et al. | A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans-based product on functional intestinal gas symptoms. | 2009 | BMC Gastroenterol | pmid:19922649 |
| Kobayashi K et al. | Photocatalytic decomposition of organic thin films in a nanometer-scale by an atomic force microscope. | 2009 | J Nanosci Nanotechnol | pmid:19504857 |
| Yonezawa T et al. | Saturated fatty acids stimulate and insulin suppresses CIDE-A expression in bovine mammary epithelial cells. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19427838 |
| Kessler W et al. | Using scattering and absorption spectra as MCR-hard model constraints for diffuse reflectance measurements of tablets. | 2009 | Anal. Chim. Acta | pmid:19427467 |
| Hesta M et al. | The effect of vitamin C supplementation in healthy dogs on antioxidative capacity and immune parameters. | 2009 | J Anim Physiol Anim Nutr (Berl) | pmid:19386005 |
| Thumma S and Repka MA | Compatibility studies of promethazine hydrochloride with tablet excipients by means of thermal and non-thermal methods. | 2009 | Pharmazie | pmid:19348341 |
| Deb C et al. | A novel in vitro multiple-stress dormancy model for Mycobacterium tuberculosis generates a lipid-loaded, drug-tolerant, dormant pathogen. | 2009 | PLoS ONE | pmid:19562030 |
| Ahn S et al. | Biochemical characterization of the lipid-binding properties of a broccoli cuticular wax-associated protein, WAX9D, and its application. | 2009 | BMB Rep | pmid:19558796 |
| van Die MD et al. | Are we drawing the right conclusions from randomised placebo-controlled trials? A post-hoc analysis of data from a randomised controlled trial. | 2009 | BMC Med Res Methodol | pmid:19549306 |
| Late SG et al. | Effects of disintegration-promoting agent, lubricants and moisture treatment on optimized fast disintegrating tablets. | 2009 | Int J Pharm | pmid:18778759 |
| Peter A et al. | Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo. | 2009 | Diabetes | pmid:19478146 |
| Ussher JR et al. | Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. | 2009 | Diabetes | pmid:19478144 |
| Monajjemzadeh F et al. | Assessment of feasibility of maillard reaction between baclofen and lactose by liquid chromatography and tandem mass spectrometry, application to pre formulation studies. | 2009 | AAPS PharmSciTech | pmid:19455427 |
| Barakat NS et al. | Controlled-release carbamazepine matrix granules and tablets comprising lipophilic and hydrophilic components. | 2009 | Drug Deliv | pmid:19555310 |