| MeSH term | MeSH ID | Detail |
|---|---|---|
| Mycobacterium Infections, Nontuberculous | D009165 | 8 associated lipids |
| Lymphadenitis | D008199 | 8 associated lipids |
| Liver Neoplasms | D008113 | 8 associated lipids |
| Leprosy | D007918 | 8 associated lipids |
| Urethritis | D014526 | 9 associated lipids |
| Brain Diseases, Metabolic, Inborn | D020739 | 10 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Acquired Immunodeficiency Syndrome | D000163 | 12 associated lipids |
| Amnesia | D000647 | 12 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Haghjou N et al. | Sustained release intraocular drug delivery devices for treatment of uveitis. | 2011 | J Ophthalmic Vis Res | pmid:22454753 |
| Liu Z et al. | [Chemical constituents from root bark of Tripterygium hypoglaucum]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22256754 |
| Uchino T et al. | Effects of coating materials and size of titanium dioxide particles on their cytotoxicity and penetration into the cellular membrane. | 2011 | J Toxicol Sci | pmid:21297346 |
| Shin S et al. | Time-oriented experimental design method to optimize hydrophilic matrix formulations with gelation kinetics and drug release profiles. | 2011 | Int J Pharm | pmid:21251963 |
| Calegari VC et al. | Inflammation of the hypothalamus leads to defective pancreatic islet function. | 2011 | J. Biol. Chem. | pmid:21257748 |
| Uchimoto T et al. | A comparative study of glycerin fatty acid ester and magnesium stearate on the dissolution of acetaminophen tablets using the analysis of available surface area. | 2011 | Eur J Pharm Biopharm | pmid:21284955 |
| Subczynski WK et al. | Spin-label oximetry at Q- and W-band. | 2011 | J. Magn. Reson. | pmid:21277814 |
| Potta SG et al. | Preparation and characterization of ibuprofen solid lipid nanoparticles with enhanced solubility. | 2011 | J Microencapsul | pmid:21171818 |
| Mosca M et al. | Effect of membrane composition on lipid oxidation in liposomes. | 2011 | Chem. Phys. Lipids | pmid:21185813 |
| de Lima-Salgado TM et al. | Molecular mechanisms by which saturated fatty acids modulate TNF-α expression in mouse macrophage lineage. | 2011 | Cell Biochem. Biophys. | pmid:20809180 |
| James J et al. | Two-dimensional surface properties of PEO-PPO-PEO triblock copolymer film at the air/water interface in the absence and presence of Tyr-Phe dipeptide, Val-Tyr-Val tripeptide, SDS and stearic acid. | 2011 | Colloids Surf B Biointerfaces | pmid:20888193 |
| Park MY et al. | Hog millet (Panicum miliaceum L.)-supplemented diet ameliorates hyperlipidemia and hepatic lipid accumulation in C57BL/6J-ob/ob mice. | 2011 | Nutr Res Pract | pmid:22259675 |
| Basu B et al. | Formulation and evaluation of fast dissolving tablets of cinnarizine using superdisintegrant blends and subliming material. | 2011 | J Adv Pharm Technol Res | pmid:22247895 |
| Ely DR and Carvajal MT | Determination of the scale of segregation of low dose tablets using hyperspectral imaging. | 2011 | Int J Pharm | pmid:21601625 |
| Zhang Y and Clapp A | Overview of stabilizing ligands for biocompatible quantum dot nanocrystals. | 2011 | Sensors (Basel) | pmid:22247651 |
| Jishnu V et al. | Formulation and evaluation of cephalexin extended release matrix tablets using 3 factorial design. | 2011 | J Young Pharm | pmid:22224031 |
| Oosterveer MH et al. | Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. | 2011 | Nutr Metab (Lond) | pmid:22201701 |
| Raynes Greenow CH et al. | Antibiotics for ureaplasma in the vagina in pregnancy. | 2011 | Cochrane Database Syst Rev | pmid:21901685 |
| Chen M et al. | [Study on the chemical constituents from Fructus Toosendan (III)]. | 2011 | Zhong Yao Cai | pmid:22500422 |
| Steidl S et al. | Mâ‚… muscarinic receptors mediate striatal dopamine activation by ventral tegmental morphine and pedunculopontine stimulation in mice. | 2011 | PLoS ONE | pmid:22102904 |
| Meissner M et al. | Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate. | 2011 | PLoS ONE | pmid:22087215 |
| Wu DJ et al. | Metabonomics-based omics study and atherosclerosis. | 2011 | J Clin Bioinforma | pmid:22040517 |
| Guschina I et al. | Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice. | 2011 | Lipids | pmid:20963507 |
| Walash MI et al. | Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids. | 2011 | Chem Cent J | pmid:21996025 |
| Protière M et al. | Rational design of the gram-scale synthesis of nearly monodisperse semiconductor nanocrystals. | 2011 | Nanoscale Res Lett | pmid:21791060 |
| Rajendraprasad N et al. | Titrimetric and spectrophotometric assay of oxcarbazepine in pharmaceuticals using N-bromosuccinimide and bromopyrogallol red. | 2011 | Int J Anal Chem | pmid:21785594 |
| Bhope SG et al. | Design and development of a stable polyherbal formulation based on the results of compatibility studies. | 2011 | Pharmacognosy Res | pmid:21772756 |
| Williams KJ et al. | The Mycobacterium tuberculosis β-oxidation genes echA5 and fadB3 are dispensable for growth in vitro and in vivo. | 2011 | Tuberculosis (Edinb) | pmid:21764638 |
| Zhang H et al. | Seed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related Pathways. | 2011 | Evid Based Complement Alternat Med | pmid:21760826 |
| Raza A and Zia-Ul-Haq M | Application of Certain π-Acceptors for the Spectrophotometric Determination of Alendronate Sodium in Pharmaceutical Bulk and Dosage Forms. | 2011 | Int J Anal Chem | pmid:21760789 |
| Abdulrahman SA and Basavaiah K | Sensitive and selective spectrophotometric determination of gabapentin in capsules using two nitrophenols as chromogenic agents. | 2011 | Int J Anal Chem | pmid:21760787 |
| Zenita O and Basavaiah K | Utility of N-bromosuccinimide for the titrimetric and spectrophotometric determination of famotidine in pharmaceutical formulations. | 2011 | Int J Anal Chem | pmid:21760785 |
| Almer G et al. | Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques. | 2011 | Int J Nanomedicine | pmid:21753879 |
| Brown JD et al. | VLDL hydrolysis by hepatic lipase regulates PPARδ transcriptional responses. | 2011 | PLoS ONE | pmid:21750705 |
| Fernandez C et al. | Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice. | 2011 | PLoS ONE | pmid:21738729 |
| Lacaze C et al. | The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. | 2011 | Malar. J. | pmid:21605361 |
| Houmard JA et al. | Is there a metabolic program in the skeletal muscle of obese individuals? | 2011 | J Obes | pmid:21603262 |
| Li C et al. | Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. | 2011 | Carcinogenesis | pmid:21586513 |
| Mahdi ES et al. | Effect of surfactant and surfactant blends on pseudoternary phase diagram behavior of newly synthesized palm kernel oil esters. | 2011 | Drug Des Devel Ther | pmid:21792294 |
| Kalinina OV et al. | Combinations of protein-chemical complex structures reveal new targets for established drugs. | 2011 | PLoS Comput. Biol. | pmid:21573205 |
| Amaya KR et al. | Small molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometry. | 2011 | J. Neurochem. | pmid:21496023 |
| Duangjit S et al. | Characterization and In Vitro Skin Permeation of Meloxicam-Loaded Liposomes versus Transfersomes. | 2011 | J Drug Deliv | pmid:21490750 |
| Liu Y et al. | Graphene and graphene oxide: two ideal choices for the enrichment and ionization of long-chain fatty acids free from matrix-assisted laser desorption/ionization matrix interference. | 2011 | Rapid Commun. Mass Spectrom. | pmid:22006384 |
| Fabiano A et al. | Metabolomic analysis of bronchoalveolar lavage fluid in preterm infants complicated by respiratory distress syndrome: preliminary results. | 2011 | J. Matern. Fetal. Neonatal. Med. | pmid:21781003 |
| Santos GM et al. | Negative regulation by nuclear receptors: a plethora of mechanisms. | 2011 | Trends Endocrinol. Metab. | pmid:21196123 |
| Watanabe H et al. | Biosynthetic Pathway for Sex Pheromone Components Produced in a Plusiinae Moth, Plusia festucae. | 2011 | Front Endocrinol (Lausanne) | pmid:22649385 |
| Yee JK et al. | Organ-specific alterations in fatty acid de novo synthesis and desaturation in a rat model of programmed obesity. | 2011 | Lipids Health Dis | pmid:21569358 |
| Shivanand K et al. | In vivo bioavailability studies of sumatriptan succinate buccal tablets. | 2011 | Daru | pmid:22615661 |
| Gande S and Rao Y | Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. | 2011 | Daru | pmid:22615658 |
| Varshosaz J et al. | Development of novel budesonide pellets based on CODES(TM) technology: In vitro/in vivo evaluation in induced colitis in rats. | 2011 | Daru | pmid:22615647 |
| Dey S et al. | Formulation and optimization of sustained release Stavudine microspheres using response surface methodology. | 2011 | ISRN Pharm | pmid:22389855 |
| Prajapati ST et al. | Formulation and evaluation of controlled-release tablet of zolpidem tartrate by melt granulation technique. | 2011 | ISRN Pharm | pmid:22389845 |
| Flowers MT et al. | Metabolic changes in skin caused by Scd1 deficiency: a focus on retinol metabolism. | 2011 | PLoS ONE | pmid:21573029 |
| Mantzaris MD et al. | Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells. | 2011 | FEBS J. | pmid:21182590 |
| Dasu MR and Jialal I | Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. | 2011 | Am. J. Physiol. Endocrinol. Metab. | pmid:20959532 |
| Kouskoumvekaki I and Panagiotou G | Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. | 2011 | J. Biomed. Biotechnol. | pmid:20936122 |
| Goto T et al. | Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist. | 2011 | Biochem. J. | pmid:21605082 |
| Kasliwal N et al. | Formulation, development, and performance evaluation of metoclopramide HCl oro-dispersible sustained release tablet. | 2011 | Arch. Pharm. Res. | pmid:22076769 |
| Wang GG et al. | Self-assembled biomimetic superhydrophobic CaCO3 coating inspired from fouling mineralization in geothermal water. | 2011 | Langmuir | pmid:21919516 |
| Asahi H et al. | Plasmodium falciparum: differing effects of non-esterified fatty acids and phospholipids on intraerythrocytic growth in serum-free medium. | 2011 | Exp. Parasitol. | pmid:21095186 |
| Kushner J et al. | Examining the impact of excipient material property variation on drug product quality attributes: a quality-by-design study for a roller compacted, immediate release tablet. | 2011 | J Pharm Sci | pmid:21319161 |
| de Sousa Neto D et al. | Effect of the ω-acylceramides on the lipid organization of stratum corneum model membranes evaluated by X-ray diffraction and FTIR studies (Part I). | 2011 | Chem. Phys. Lipids | pmid:21238439 |
| Seow LJ et al. | Anti-angiogenic activity of Gynura segetum leaf extracts and its fractions. | 2011 | J Ethnopharmacol | pmid:21167271 |
| Price ER et al. | Carnitine palmitoyl transferase activity and whole muscle oxidation rates vary with fatty acid substrate in avian flight muscles. | 2011 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:21153644 |
| Lin Y et al. | Nucleating effect of calcium stearate coated CaCO(3) nanoparticles on polypropylene. | 2011 | J Colloid Interface Sci | pmid:21122873 |
| MacDonald AM et al. | A modified supported bilayer/diblock polymer--working towards a tunable coating for capillary electrophoresis. | 2011 | J Chromatogr A | pmid:21122870 |
| Liu X et al. | Synthesis of high quality and stability CdS quantum dots with overlapped nucleation-growth process in large scale. | 2011 | J Colloid Interface Sci | pmid:21040929 |
| Tamilvanan S et al. | In vitro and in vivo evaluation of hydrophilic and hydrophobic polymers-based nicorandil-loaded peroral tablet compared with its once-daily commercial sustained-release tablet. | 2011 | Drug Dev Ind Pharm | pmid:20923389 |
| Liu H et al. | A surfactant-free recipe for shape-controlled synthesis of CdSe nanocrystals. | 2011 | Nanotechnology | pmid:21169661 |
| Pingali K et al. | Mixing order of glidant and lubricant--influence on powder and tablet properties. | 2011 | Int J Pharm | pmid:21356286 |
| Zaki Rizkalla CM et al. | In vitro and in vivo evaluation of hydroxyzine hydrochloride microsponges for topical delivery. | 2011 | AAPS PharmSciTech | pmid:21800216 |
| Roblegg E et al. | Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion. | 2011 | Eur J Pharm Biopharm | pmid:21801834 |
| Van Hoeck V et al. | Elevated non-esterified fatty acid concentrations during bovine oocyte maturation compromise early embryo physiology. | 2011 | PLoS ONE | pmid:21858021 |
| El Andaloussi S et al. | Cell-penetrating peptides-based strategies for the delivery of splice redirecting antisense oligonucleotides. | 2011 | Methods Mol. Biol. | pmid:21748634 |
| Li Y et al. | Building layer-by-layer 3D supramolecular nanostructures at the terephthalic acid/stearic acid interface. | 2011 | Chem. Commun. (Camb.) | pmid:21755081 |
| Morinaga N et al. | Synthesis of fatty acid sterol esters using cholesterol esterase from Trichoderma sp. AS59. | 2011 | Enzyme Microb. Technol. | pmid:22113022 |
| Kumar A et al. | Phytochemical investigation and antifeedant activity of Premna latifolia leaves. | 2011 | Nat. Prod. Res. | pmid:21756197 |
| Hirose A et al. | Clofibric acid increases the formation of oleic acid in endoplasmic reticulum of the liver of rats. | 2011 | J. Pharmacol. Sci. | pmid:21757842 |
| Choi SE et al. | Capsaicin attenuates palmitate-induced expression of macrophage inflammatory protein 1 and interleukin 8 by increasing palmitate oxidation and reducing c-Jun activation in THP-1 (human acute monocytic leukemia cell) cells. | 2011 | Nutr Res | pmid:21745629 |
| Fameau AL et al. | Smart foams: switching reversibly between ultrastable and unstable foams. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21780260 |
| Gremos S et al. | Direct enzymatic acylation of cellulose pretreated in BMIMCl ionic liquid. | 2011 | Bioresour. Technol. | pmid:20888759 |
| Li S et al. | Preparation, characterization, pharmacokinetics and tissue distribution of solid lipid nanoparticles loaded with tetrandrine. | 2011 | AAPS PharmSciTech | pmid:21811889 |
| Perrault M et al. | An experimental investigation of the effect of the amount of lubricant on tablet properties. | 2011 | Drug Dev Ind Pharm | pmid:20704461 |
| Cheng YY et al. | A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. | 2011 | Int J Mol Sci | pmid:22072918 |
| Peng Q et al. | A novel esterase gene cloned from a metagenomic library from neritic sediments of the South China Sea. | 2011 | Microb. Cell Fact. | pmid:22067554 |
| Yu WL et al. | Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae. | 2011 | Microb. Cell Fact. | pmid:22047615 |
| Someshwar K et al. | Formulation and evaluation of effervescent floating tablets of tizanidine hydrochloride. | 2011 | Acta Pharm | pmid:21684848 |
| Sekharan TR et al. | Formulation and Evaluation of Hydroxypropyl Methylcellulose-based Controlled Release Matrix Tablets for Theophylline. | 2011 | Indian J Pharm Sci | pmid:22707833 |
| Pani NR et al. | Compatibility studies of nateglinide with excipients in immediate release tablets. | 2011 | Acta Pharm | pmid:21684850 |
| Nagarsekar KS et al. | Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract of leaves of vitex negundo linn. | 2011 | Indian J Pharm Sci | pmid:22707827 |
| Němcová-Fürstová V et al. | Inhibitory effect of unsaturated fatty acids on saturated fatty acid-induced apoptosis in human pancreatic β-cells: activation of caspases and ER stress induction. | 2011 | Cell. Physiol. Biochem. | pmid:21691070 |
| Xu M et al. | Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism. | 2011 | J. Biol. Chem. | pmid:21697096 |
| White HM et al. | Differential regulation of bovine pyruvate carboxylase promoters by fatty acids and peroxisome proliferator-activated receptor-α agonist. | 2011 | J. Dairy Sci. | pmid:21700028 |
| Farboud ES et al. | Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies. | 2011 | Int J Nanomedicine | pmid:21674018 |
| Tiţa B et al. | Compatibility study between ketoprofen and pharmaceutical excipients used in solid dosage forms. | 2011 | J Pharm Biomed Anal | pmid:21665404 |
| Mercado FV et al. | Phase diagram of mixed monolayers of stearic acid and dimyristoylphosphatidylcholine. Effect of the acid ionization. | 2011 | Chem. Phys. Lipids | pmid:21635875 |
| Abbasi M et al. | siRNA-mediated down-regulation of P-glycoprotein in a Xenograft tumor model in NOD-SCID mice. | 2011 | Pharm. Res. | pmid:21638135 |
| Lan DM et al. | A novel cold-active lipase from Candida albicans: cloning, expression and characterization of the recombinant enzyme. | 2011 | Int J Mol Sci | pmid:21747717 |
| Lee YJ and Jenkins TC | Biohydrogenation of linolenic acid to stearic acid by the rumen microbial population yields multiple intermediate conjugated diene isomers. | 2011 | J. Nutr. | pmid:21653571 |
| Sloat BR et al. | In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles. | 2011 | Int J Pharm | pmid:21371545 |