| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Gonorrhea | D006069 | 7 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen Y et al. | A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. | 2010 | Appl Spectrosc | pmid:20925991 |
| Mukherjee S et al. | Stearic acid delivery to corneum from a mild and moisturizing cleanser. | 2010 | J Cosmet Dermatol | pmid:20883293 |
| Rawat MK et al. | Effect of lipid matrix on repaglinide-loaded solid lipid nanoparticles for oral delivery. | 2010 | Ther Deliv | pmid:22816120 |
| Patra S et al. | In vitro evaluation of domperidone mouth dissolving tablets. | 2010 | Indian J Pharm Sci | pmid:21969764 |
| Zornetzer GA et al. | The length of the bound fatty acid influences the dynamics of the acyl carrier protein and the stability of the thioester bond. | 2010 | Biochemistry | pmid:20014832 |
| Shen J et al. | Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: Improving in vivo ocular distribution. | 2010 | Int J Pharm | pmid:20934499 |
| Renaville B et al. | Plasma and follicular fluid fatty acid profiles in dairy cows. | 2010 | Reprod. Domest. Anim. | pmid:19055554 |
| Varshosaz J et al. | Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. | 2010 | Int J Prev Med | pmid:21566772 |
| Alizadeh M et al. | The effect of hypocaloric diet enriched in legumes with or without L-arginine and selenium on anthropometric measures in central obese women. | 2010 | J Res Med Sci | pmid:21526106 |
| Ospina-E JC et al. | Development of combinations of chemically modified vegetable oils as pork backfat substitutes in sausages formulation. | 2010 | Meat Sci. | pmid:20374815 |
| Ye S et al. | Polyunsaturated docosahexaenoic acid suppresses oxidative stress induced endothelial cell calcium influx by altering lipid composition in membrane caveolar rafts. | 2010 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:20206488 |
| Rajab M et al. | Optimization of a metformin effervescent floating tablet containing hydroxypropylmethylcellulose and stearic acid. | 2010 | Pharmazie | pmid:20225651 |
| Araújo J et al. | Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. | 2010 | Int J Pharm | pmid:20362042 |
| Bender K et al. | Metabolite concentrations in follicular fluid may explain differences in fertility between heifers and lactating cows. | 2010 | Reproduction | pmid:20385782 |
| Pedersen PJ et al. | Liposomal formulation of retinoids designed for enzyme triggered release. | 2010 | J. Med. Chem. | pmid:20405849 |
| Liew CV et al. | In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. | 2010 | Int J Pharm | pmid:19922776 |
| Ohwoavworhua FO and Adelakun TA | Non-wood Fibre Production of Microcrystalline Cellulose from Sorghum caudatum: Characterisation and Tableting Properties. | 2010 | Indian J Pharm Sci | pmid:21188036 |
| El Hadrami A et al. | Chitosan in plant protection. | 2010 | Mar Drugs | pmid:20479963 |
| Borah BM et al. | Surface-modification-directed controlled adsorption of serum albumin onto magnetite nanocuboids synthesized in a gel-diffusion technique. | 2010 | J Colloid Interface Sci | pmid:20621808 |
| Zhu SH et al. | [Study on the chemical constituents of Dichrocephala integrifolia]. | 2010 | Zhong Yao Cai | pmid:20518304 |
| Manickam E et al. | Suppressive actions of eicosapentaenoic acid on lipid droplet formation in 3T3-L1 adipocytes. | 2010 | Lipids Health Dis | pmid:20525346 |
| Luan L et al. | [Studies on the chemical constituents of extract with water from Forsythia suspensa]. | 2010 | Zhong Yao Cai | pmid:20575415 |
| Contreras GA et al. | Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. | 2010 | J. Dairy Sci. | pmid:20494158 |
| Karande AD et al. | In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. | 2010 | Int J Pharm | pmid:20558264 |
| Kim IS and Oh IJ | Preparation and characterization of stearic acid-pullulan nanoparticles. | 2010 | Arch. Pharm. Res. | pmid:20512475 |
| Wang J et al. | Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. | 2010 | J Pharm Sci | pmid:20533436 |
| Thörn K et al. | Reduced levels of SCD1 accentuate palmitate-induced stress in insulin-producing β-cells. | 2010 | Lipids Health Dis | pmid:20920255 |
| Aly S | Detachment and recovery index: A new parameter measuring powder compressibility. | 2010 | J Adv Pharm Technol Res | pmid:22247881 |
| Pires de Souza FC et al. | In vitro comparison of the radiopacity of cavity lining materials with human dental structures. | 2010 | J Conserv Dent | pmid:20859477 |
| Lyra A et al. | Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes. | 2010 | BMC Gastroenterol | pmid:20849659 |
| Shishu VR et al. | Development of taste masked oral formulation of ornidazole. | 2010 | Indian J Pharm Sci | pmid:20838525 |
| Gohel MC et al. | Fabrication and Evaluation of Bi-layer Tablet Containing Conventional Paracetamol and Modified Release Diclofenac Sodium. | 2010 | Indian J Pharm Sci | pmid:20838522 |
| Phaechamud T et al. | Preparation of Coated Valproic Acid and Sodium Valproate Sustained-release Matrix Tablets. | 2010 | Indian J Pharm Sci | pmid:20838520 |
| Huthmacher C et al. | Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. | 2010 | BMC Syst Biol | pmid:20807400 |
| Do PT et al. | The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. | 2010 | Plant Physiol. | pmid:20841452 |
| Xu Y et al. | Carbon-covered magnetic nanomaterials and their application for the thermolysis of cancer cells. | 2010 | Int J Nanomedicine | pmid:20463932 |
| Harvey KA et al. | Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells. | 2010 | J. Lipid Res. | pmid:20852092 |
| Prossnigg F et al. | Packing behaviour of two predominant anionic phospholipids of bacterial cytoplasmic membranes. | 2010 | Biophys. Chem. | pmid:20451316 |
| Chitapanarux I et al. | Randomized controlled trial of live lactobacillus acidophilus plus bifidobacterium bifidum in prophylaxis of diarrhea during radiotherapy in cervical cancer patients. | 2010 | Radiat Oncol | pmid:20444243 |
| Blanco M and Peguero A | Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. | 2010 | J Pharm Biomed Anal | pmid:20044229 |
| Swanson EJ et al. | Phospholipid-stabilized microbubble foam for injectable oxygen delivery. | 2010 | Langmuir | pmid:20873807 |
| Howell AB et al. | Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content: a multicentric randomized double blind study. | 2010 | BMC Infect. Dis. | pmid:20398248 |
| Yasuda A et al. | Self-organizing map analysis using multivariate data from theophylline powders predicted by a thin-plate spline interpolation. | 2010 | J Pharm Sci | pmid:20845452 |
| UÄŸurlu T et al. | Effects of lubricants on binary direct compression mixtures. | 2010 | Drug Discov Ther | pmid:22491169 |
| Shaikh SA et al. | Formulation and evaluation of s-(-)-amlodipine besylate and nebivolol hydrochloride tablets. | 2010 | J Adv Pharm Technol Res | pmid:22247846 |
| Tiwari G et al. | Cyclodextrins in delivery systems: Applications. | 2010 | J Pharm Bioallied Sci | pmid:21814436 |
| Hsieh HT et al. | Facile synthesis of silver nanoparticles in CO2-expanded liquids from silver isostearate precursor. | 2010 | Langmuir | pmid:20297774 |
| van den Berg SA et al. | High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity. | 2010 | Nutr Metab (Lond) | pmid:20346174 |
| Xing Z et al. | Novel ultrasound contrast agent based on microbubbles generated from surfactant mixtures of Span 60 and polyoxyethylene 40 stearate. | 2010 | Acta Biomater | pmid:20226284 |
| Choi JN et al. | Metabolomics revealed novel isoflavones and optimal cultivation time of Cordyceps militaris fermentation. | 2010 | J. Agric. Food Chem. | pmid:20225861 |
| Desando MA et al. | Proton magnetic relaxation and the aggregation of n-octylammonium n-octadecanoate surfactant in deuterochloroform solution. | 2010 | J Colloid Interface Sci | pmid:20223468 |
| Collins JM et al. | De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. | 2010 | J. Biol. Chem. | pmid:20032470 |
| Xing Z et al. | The fabrication of novel nanobubble ultrasound contrast agent for potential tumor imaging. | 2010 | Nanotechnology | pmid:20220227 |
| Li Y et al. | Preparation and characterization of coverage-controlled CaCO3 nanoparticles. | 2010 | J Colloid Interface Sci | pmid:20202642 |
| Salbu L et al. | Direct compression behavior of low- and high-methoxylated pectins. | 2010 | AAPS PharmSciTech | pmid:20013080 |
| Romanowicz L and Bańkowski E | Sphingolipids of human umbilical cord vein and their alteration in preeclampsia. | 2010 | Mol. Cell. Biochem. | pmid:20155487 |
| Kordyukova LV et al. | Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. | 2010 | Virology | pmid:20006369 |
| Abdel-Mottaleb MM et al. | In vitro drug release mechanism from lipid nanocapsules (LNC). | 2010 | Int J Pharm | pmid:20149853 |
| Raeside JI and Christie HL | Diaryl dimers of estradiol and of estrone may be formed as major metabolites by mouse mammary glands. | 2010 | Biochem. Biophys. Res. Commun. | pmid:20875396 |
| Romanowicz L and Bańkowski E | Altered sphingolipid composition in Wharton's jelly of pre-eclamptic newborns. | 2010 | Pathobiology | pmid:20332667 |
| Alshamsan A et al. | Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. | 2009 Jan-Feb | Mol. Pharm. | pmid:19053537 |
| Snoeren TA et al. | Multidisciplinary approach to unravelling the relative contribution of different oxylipins in indirect defense of Arabidopsis thaliana. | 2009 | J. Chem. Ecol. | pmid:19798534 |
| Atherton HJ et al. | Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse. | 2009 | Mol. Syst. Biol. | pmid:19357638 |
| HÃ¥versen L et al. | Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. | 2009 | Atherosclerosis | pmid:18599066 |
| Roberts R et al. | Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans. | 2009 | Diabetologia | pmid:19252892 |
| Shehab-El-Deen MA et al. | Cryotolerance of bovine blastocysts is affected by oocyte maturation in media containing palmitic or stearic acid. | 2009 | Reprod. Domest. Anim. | pmid:18992093 |
| Malaterre V et al. | Benchtop-magnetic resonance imaging (BT-MRI) characterization of push-pull osmotic controlled release systems. | 2009 | J Control Release | pmid:18840483 |
| Burkhardt M et al. | Macroscopic properties and microstructure of HSA based organogels: sensitivity to polar additives. | 2009 | J Colloid Interface Sci | pmid:19144353 |
| Chen Y et al. | Observation of an amorphous calcium carbonate precursor on a stearic acid monolayer formed during the biomimetic mineralization of CaCO(3). | 2009 | Langmuir | pmid:19099353 |
| Mäe M et al. | A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy. | 2009 | J Control Release | pmid:19105971 |
| Schmidt WF et al. | Unit cell volume and liquid-phase immiscibility in oleate-stearate lipid mixtures. | 2009 | Chem. Phys. Lipids | pmid:19150441 |
| Berry SE | Triacylglycerol structure and interesterification of palmitic and stearic acid-rich fats: an overview and implications for cardiovascular disease. | 2009 | Nutr Res Rev | pmid:19442321 |
| Pingali KC et al. | Practical methods for improving flow properties of active pharmaceutical ingredients. | 2009 | Drug Dev Ind Pharm | pmid:19929205 |
| Le Guédard M et al. | PSI1 is responsible for the stearic acid enrichment that is characteristic of phosphatidylinositol in yeast. | 2009 | FEBS J. | pmid:19796168 |
| Nokhodchi A et al. | Cogrinding as a tool to produce sustained release behavior for theophylline particles containing magnesium stearate. | 2009 | AAPS PharmSciTech | pmid:19862623 |
| Okada K et al. | Effect of fatty acids added to the milk replacer on white scour and excretion of fatty acids in Holstein calves. | 2009 | Anim. Sci. J. | pmid:20163618 |
| Costa MC et al. | The solid-liquid phase diagrams of binary mixtures of consecutive, even saturated fatty acids. | 2009 | Chem. Phys. Lipids | pmid:19520067 |
| Prajapati ST et al. | Studies on formulation and in vitro evaluation of floating matrix tablets of domperidone. | 2009 | Indian J Pharm Sci | pmid:20177450 |
| Wei Y et al. | Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells. | 2009 | Mol. Cell. Biochem. | pmid:19444596 |
| Kalman DS et al. | A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans-based product on functional intestinal gas symptoms. | 2009 | BMC Gastroenterol | pmid:19922649 |
| Fostok SF et al. | Interleukin-6 and Cyclooxygenase-2 downregulation by fatty-acid fractions of Ranunculus constantinopolitanus. | 2009 | BMC Complement Altern Med | pmid:19917107 |
| Evans LM et al. | Stearate preferentially induces apoptosis in human breast cancer cells. | 2009 | Nutr Cancer | pmid:19838949 |
| Mukherjee S and Datta A | Morphology and structural evolution in cobalt stearate Langmuir-Blodgett films. | 2009 | J Nanosci Nanotechnol | pmid:19928206 |
| Yarkala S et al. | Role of excipients on N-oxide raloxifene generation from raloxifene-excipients binary mixtures. | 2009 | Chem. Pharm. Bull. | pmid:19801885 |
| Fujita M et al. | Generation of formaldehyde by pharmaceutical excipients and its absorption by meglumine. | 2009 | Chem. Pharm. Bull. | pmid:19801864 |
| Gängler P et al. | In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel. | 2009 | BMC Oral Health | pmid:19799785 |
| Cha KH et al. | Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia. | 2009 | Arch. Pharm. Res. | pmid:20091273 |
| Hesta M et al. | The effect of vitamin C supplementation in healthy dogs on antioxidative capacity and immune parameters. | 2009 | J Anim Physiol Anim Nutr (Berl) | pmid:19386005 |
| Thumma S and Repka MA | Compatibility studies of promethazine hydrochloride with tablet excipients by means of thermal and non-thermal methods. | 2009 | Pharmazie | pmid:19348341 |
| Bolhuis GK et al. | Compaction properties of isomalt. | 2009 | Eur J Pharm Biopharm | pmid:19327398 |
| Staiger K et al. | Protein kinase C iota mediates lipid-induced apoptosis of human coronary artery endothelial cells. | 2009 | Microvasc. Res. | pmid:19327373 |
| Late SG et al. | Effects of disintegration-promoting agent, lubricants and moisture treatment on optimized fast disintegrating tablets. | 2009 | Int J Pharm | pmid:18778759 |
| Alloatti A et al. | Chemical evaluation of fatty acid desaturases as drug targets in Trypanosoma cruzi. | 2009 | Int. J. Parasitol. | pmid:19249306 |
| Ishikado A et al. | Soy phosphatidylcholine inhibited TLR4-mediated MCP-1 expression in vascular cells. | 2009 | Atherosclerosis | pmid:19215923 |
| Ussher JR et al. | Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. | 2009 | Diabetes | pmid:19478144 |
| Yang Y et al. | Radial-position-controlled doping of CdS/ZnS core/shell nanocrystals: surface effects and position-dependent properties. | 2009 | Chemistry | pmid:19206119 |
| Monajjemzadeh F et al. | Assessment of feasibility of maillard reaction between baclofen and lactose by liquid chromatography and tandem mass spectrometry, application to pre formulation studies. | 2009 | AAPS PharmSciTech | pmid:19455427 |
| Nyadong L et al. | Combining two-dimensional diffusion-ordered nuclear magnetic resonance spectroscopy, imaging desorption electrospray ionization mass spectrometry, and direct analysis in real-time mass spectrometry for the integral investigation of counterfeit pharmaceuticals. | 2009 | Anal. Chem. | pmid:19453162 |
| Meng W et al. | A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. | 2009 | Trials | pmid:19419555 |
| Brach Del Prever EM et al. | UHMWPE for arthroplasty: past or future? | 2009 | J Orthop Traumatol | pmid:19384628 |