stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Dermatitis, Contact D003877 59 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Edema D004487 152 associated lipids
Fatty Liver D005234 48 associated lipids
Foreign Bodies D005547 5 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Gonorrhea D006069 7 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Varghese N et al. Investigations of the growth kinetics of capped CdSe and CdS nanocrystals by a combined use of small angle X-ray scattering and other techniques. 2008 Chem Asian J pmid:18637656
Shah DA et al. Stability Indicating RP-HPLC Estimation of Nebivolol Hydrochloride in Pharmaceutical Formulations. 2008 Indian J Pharm Sci pmid:21394254
Gonçalves-Araújo T et al. Application of percolation theory in the study of an extended release Verapamil hydrochloride formulation. 2008 Int J Pharm pmid:18621491
Labonté ED et al. Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice. 2008 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:18718999
Late SG and Banga AK Thermal and non-thermal methods to evaluate compatibility of granisetron hydrochloride with tablet excipients. 2008 Pharmazie pmid:18604989
Sachse F et al. Anti-inflammatory effects of ciprofloxacin in S. aureus Newman induced nasal inflammation in vitro. 2008 J Inflamm (Lond) pmid:18664275
De Girolamo J et al. Layer-by-layer assembled composite films of side-functionalized poly(3-hexylthiophene) and CdSe nanocrystals: electrochemical, spectroelectrochemical and photovoltaic properties. 2008 Phys Chem Chem Phys pmid:18597017
Reyna SM et al. Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. 2008 Diabetes pmid:18633101
Ikonen M et al. Controlled complexation of plasmid DNA with cationic polymers: effect of surfactant on the complexation and stability of the complexes. 2008 Colloids Surf B Biointerfaces pmid:18583110
Yee JK et al. Compartmentalization of stearoyl-coenzyme A desaturase 1 activity in HepG2 cells. 2008 J. Lipid Res. pmid:18599738
Shah RB et al. Stability indicating validated HPLC method for quantification of levothyroxine with eight degradation peaks in the presence of excipients. 2008 Int J Pharm pmid:18524511
Bermúdez L et al. A candidate gene survey of quantitative trait loci affecting chemical composition in tomato fruit. 2008 J. Exp. Bot. pmid:18552354
Salas JJ et al. The biochemical characterization of a high-stearic acid sunflower mutant reveals the coordinated regulation of stearoyl-acyl carrier protein desaturases. 2008 Plant Physiol. Biochem. pmid:18023195
Georget DM et al. A study on maize proteins as a potential new tablet excipient. 2008 Eur J Pharm Biopharm pmid:18294824
Sun CC On the mechanism of reduced tabletability of granules prepared by roller compaction. 2008 Int J Pharm pmid:18024020
Xie L et al. Quality-by-design (QbD): effects of testing parameters and formulation variables on the segregation tendency of pharmaceutical powder measured by the ASTM D 6940-04 segregation tester. 2008 J Pharm Sci pmid:18271036
Lee WJ and Chen YC Novolak PF resins prepared from phenol liquefied Cryptomeria japonica and used in manufacturing moldings. 2008 Bioresour. Technol. pmid:18243689
Schwab U et al. Triacylglycerol fatty acid composition in diet-induced weight loss in subjects with abnormal glucose metabolism--the GENOBIN study. 2008 PLoS ONE pmid:18612464
Kim CH et al. Effects of emulsified octadecanic acids on gas production and cellulolysis by the rumen anaerobic fungus, Piromyces communis M014. 2008 Anaerobe pmid:17996466
Zaccone A et al. Correlation between colloidal stability and surfactant adsorption/association phenomena studied by light scattering. 2008 J Phys Chem B pmid:18229917
Hu FQ et al. Cellular uptake and cytotoxicity of shell crosslinked stearic acid-grafted chitosan oligosaccharide micelles encapsulating doxorubicin. 2008 Eur J Pharm Biopharm pmid:17997293
Wakasawa T et al. Solid-state compatibility studies using a high-throughput and automated forced degradation system. 2008 Int J Pharm pmid:18215480
Ivanova T et al. Action of Humicola lanuginosa lipase on mixed monomolecular films of tricaprylin and polyethylene glycol stearate. 2008 Colloids Surf B Biointerfaces pmid:18178069
Vögler O et al. Structure-effect relation of C18 long-chain fatty acids in the reduction of body weight in rats. 2008 Int J Obes (Lond) pmid:18059405
UÄŸurlu T and TurkoÄŸlu M Hexagonal boron nitride as a tablet lubricant and a comparison with conventional lubricants. 2008 Int J Pharm pmid:18160235
Tanka-Salamon A et al. Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids. Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation. 2008 FEBS J. pmid:18279394
Gianotti A et al. Involvement of cell fatty acid composition and lipid metabolism in adhesion mechanism of Listeria monocytogenes. 2008 Int. J. Food Microbiol. pmid:18160165
Ruths M et al. Friction of fatty acids in nanometer-sized contacts of different adhesive strength. 2008 Langmuir pmid:18085802
Galperin MY Social bacteria and asocial eukaryotes. 2008 Environ. Microbiol. pmid:18199122
Harding L et al. The development of microthermal analysis and photothermal microspectroscopy as novel approaches to drug-excipient compatibility studies. 2008 Int J Pharm pmid:18162342
Zhu CQ et al. Facile Phosphine-Free Synthesis of CdSe/ZnS Core/Shell Nanocrystals Without Precursor Injection. 2008 Nanoscale Res Lett pmid:21777485
Desai D et al. Solid-state interaction of stearic acid with povidone and its effect on dissolution stability of capsules. 2008 Int J Pharm pmid:18194844
Ebbesson SO et al. Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: the Genetics of Coronary Artery Disease in Alaska Natives study. 2008 Atherosclerosis pmid:18054937
Baldania SL et al. RP-HPLC Estimation of Venlafaxine Hydrochloride in Tablet Dosage Forms. 2008 Indian J Pharm Sci pmid:20390099
Garay AS and Rodrigues DE Effects of the inclusion of the spin label 10-doxyl-stearic acid on the structure and dynamics of model bilayers in water: stearic acid and stearic acid/cholesterol (50:20). 2008 J Phys Chem B pmid:18198858
Patel DM and Patel MM Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique. 2008 Indian J Pharm Sci pmid:20390084
Widjaja E and Seah RK Application of Raman microscopy and band-target entropy minimization to identify minor components in model pharmaceutical tablets. 2008 J Pharm Biomed Anal pmid:17980994
Jithan AV et al. Development and evaluation of a chloramphenicol hypertonic ophthalmic solution. 2008 Indian J Pharm Sci pmid:20390083
Darwish IA et al. New spectrofluorimetric method with enhanced sensitivity for determination of paroxetine in dosage forms and plasma. 2008 Anal Chem Insights pmid:19609398
Bacher C et al. Granule fraction inhomogeneity of calcium carbonate/sorbitol in roller compacted granules. 2008 Int J Pharm pmid:17765416
Rahman N and Haque SM Optimized and validated spectrophotometric methods for the determination of enalapril maleate in commercial dosage forms. 2008 Anal Chem Insights pmid:19609388
Piao ZZ et al. Colonic release and reduced intestinal tissue damage of coated tablets containing naproxen inclusion complex. 2008 Int J Pharm pmid:17928177
El-Enany N et al. Spectrofluorimetric determination of oxamniquine in dosage forms and spiked human plasma through derivatization with 1-dimethylaminonaphthalene-5-sulphonyl chloride. 2008 J Fluoresc pmid:18058206
Yuan H et al. Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells. 2008 Int J Pharm pmid:17714896
Vehring R Pharmaceutical particle engineering via spray drying. 2008 Pharm. Res. pmid:18040761
Gmucová K et al. Orientation ordering of nanoparticle Ag/Co cores controlled by electric and magnetic fields. 2008 Chemphyschem pmid:18386264
Houmadi S et al. Langmuir-Blodgett film of hydrophobin protein from Pleurotus ostreatus at the air-water interface. 2008 Langmuir pmid:18925762
Crowe FL et al. Fatty acid composition of plasma phospholipids and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition. 2008 Am. J. Clin. Nutr. pmid:18996872
Isaev NP and Dzuba SA Fast stochastic librations and slow rotations of spin labeled stearic acids in a model phospholipid bilayer at cryogenic temperatures. 2008 J Phys Chem B pmid:18826269
Abbasi M et al. Further investigation of lipid-substituted poly(L-Lysine) polymers for transfection of human skin fibroblasts. 2008 Biomacromolecules pmid:18498191
Hasegawa K et al. Growth of beta(2)-microglobulin-related amyloid fibrils by non-esterified fatty acids at a neutral pH. 2008 Biochem. J. pmid:18637792
Hernández ML et al. The utilization and desaturation of oleate and linoleate during glycerolipid biosynthesis in olive (Olea europaea L.) callus cultures. 2008 J. Exp. Bot. pmid:18515829
Dou M et al. [Orthogonal experiments for optimizing the formulation and preparation conditions of temozolomide solid lipid nanoparticles]. 2008 Sheng Wu Yi Xue Gong Cheng Xue Za Zhi pmid:19024463
Vartorelli MR et al. Spin-labeled stearic acid behavior and perturbations on the structure of a gel-phase-lipid bilayer in water: 5-, 12- and 16-SASL. 2008 J Phys Chem B pmid:19055388
Lasserre R et al. Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation. 2008 Nat. Chem. Biol. pmid:18641634
Aoki PH et al. Sensor array made with nanostructured films to detect a phenothiazine compound. 2008 J Nanosci Nanotechnol pmid:19049023
Liu Q et al. Cobalt nanowires prepared by heterogeneous nucleation in propanediol and their catalytic properties. 2008 Nanotechnology pmid:21828879
Zhang JX et al. Sex- and gonad-affecting scent compounds and 3 male pheromones in the rat. 2008 Chem. Senses pmid:18515819
Balk M et al. Desulfatirhabdium butyrativorans gen. nov., sp. nov., a butyrate-oxidizing, sulfate-reducing bacterium isolated from an anaerobic bioreactor. 2008 Int. J. Syst. Evol. Microbiol. pmid:18175693
Ishima Y et al. S-nitrosylated human serum albumin-mediated cytoprotective activity is enhanced by fatty acid binding. 2008 J. Biol. Chem. pmid:18940810
Xue R et al. A serum metabolomic investigation on hepatocellular carcinoma patients by chemical derivatization followed by gas chromatography/mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18767022
McNamara RK et al. Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder. 2008 Psychiatry Res pmid:18715653
Xu G and Fang Y Studies of surface-enhanced Raman scattering of C60 Langmuir-Blodgett film on a new substrate. 2008 Spectrochim Acta A Mol Biomol Spectrosc pmid:17889595
Chatterjee A and Chowdhury R Bile and unsaturated fatty acids inhibit the binding of cholera toxin and Escherichia coli heat-labile enterotoxin to GM1 receptor. 2008 Antimicrob. Agents Chemother. pmid:17954701
Zeng Q et al. Highly luminescent CdSe/ZnSe core-shell quantum dots of one-pot preparation in octadecene. 2008 J Nanosci Nanotechnol pmid:18468151
Kordyukova LV et al. S acylation of the hemagglutinin of influenza viruses: mass spectrometry reveals site-specific attachment of stearic acid to a transmembrane cysteine. 2008 J. Virol. pmid:18596092
Karoussi O and Hamouda AA Macroscopic and nanoscale study of wettability alteration of oil-wet calcite surface in presence of magnesium and sulfate ions. 2008 J Colloid Interface Sci pmid:17931645
Fujio J et al. Regulation of gut-derived resistin-like molecule beta expression by nutrients. 2008 Diabetes Res. Clin. Pract. pmid:17936398
Asadi A et al. Interaction of bovine serum albumin with some novel PEG-containing diblock copolymers. 2008 Int. J. Biol. Macromol. pmid:18602419
Miguélez-Morán AM et al. The effect of lubrication on density distributions of roller compacted ribbons. 2008 Int J Pharm pmid:18602976
Wan F et al. Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro. 2008 Int J Pharm pmid:18450394
Kumon M et al. Application and mechanism of inhalation profile improvement of DPI formulations by mechanofusion with magnesium stearate. 2008 Chem. Pharm. Bull. pmid:18451547
Smirnov AI Post-processing of EPR spectra by convolution filtering: calculation of a harmonics' series and automatic separation of fast-motion components from spin-label EPR spectra. 2008 J. Magn. Reson. pmid:17967556
Zhang XG et al. Reversal activity of nanostructured lipid carriers loading cytotoxic drug in multi-drug resistant cancer cells. 2008 Int J Pharm pmid:18586075
Liu C et al. In situ intestinal absorption of cyclosporine A solid dispersion in rats. 2008 Drug Dev Ind Pharm pmid:18568913
Gotoh K et al. A quartz crystal microbalance simulation to examine the effect of ultraviolet light treatment on characteristics of polyethylene surface. 2008 J Oleo Sci pmid:18685232
Adeagbo AA and Alebiowu G Evaluation of cocoa butter as potential lubricant for coprocessing in pharmaceutical tablets. 2008 Pharm Dev Technol pmid:18484488
Cai JY et al. [Studies on chemical constituents from Anoectochilus roxburghii]. 2008 Zhong Yao Cai pmid:18619237
Ma BJ et al. [Chemical constituents study on the fruiting bodies of Lactarius rufus]. 2008 Zhong Yao Cai pmid:18619269
Fini A et al. Raman and thermal analysis of indomethacin/PVP solid dispersion enteric microparticles. 2008 Eur J Pharm Biopharm pmid:18621516
Liu LX et al. Effect of particle properties on the flowability of ibuprofen powders. 2008 Int J Pharm pmid:18652883
Lumor SE et al. Optimization of solid fat content and crystal properties of a trans-free structured lipid by blending with palm midfraction. 2008 J. Agric. Food Chem. pmid:18781758
Moon CD et al. Reclassification of Clostridium proteoclasticum as Butyrivibrio proteoclasticus comb. nov., a butyrate-producing ruminal bacterium. 2008 Int. J. Syst. Evol. Microbiol. pmid:18768601
Li Y and Weng W Surface modification of hydroxyapatite by stearic acid: characterization and in vitro behaviors. 2008 J Mater Sci Mater Med pmid:17569011
Johansson TP and Leach GW A low temperature phase transition in Langmuir-Blodgett films. 2008 J Phys Chem B pmid:18855435
Yonezawa T et al. Regulation of hormone-sensitive lipase expression by saturated fatty acids and hormones in bovine mammary epithelial cells. 2008 Biochem. Biophys. Res. Commun. pmid:18755148
Liu J et al. Size-tunable near-infrared PbS nanoparticles synthesized from lead carboxylate and sulfur with oleylamine as stabilizer. 2008 Nanotechnology pmid:21730651
Kartal A et al. Compatibility of chewing gum excipients with the amino acid L-cysteine and stability of the active substance in directly compressed chewing gum formulation. 2008 J. Pharm. Pharmacol. pmid:18718115
Panda DS et al. Evaluation of Gum of Moringa oleifera as a Binder and Release Retardant in Tablet Formulation. 2008 Indian J Pharm Sci pmid:21394258
Kundu S et al. Relaxation of bimolecular layer films on water surfaces. 2008 Langmuir pmid:18665619
Chandran S et al. Design and Evaluation of Ethyl Cellulose Based Matrix Tablets of Ibuprofen with pH Modulated Release Kinetics. 2008 Indian J Pharm Sci pmid:21394255
Teixeira AC et al. Microdomains in mixed monolayers of oleanolic and stearic acids: thermodynamic study and BAM observation at the air-water interface and AFM and FTIR analysis of LB monolayers. 2007 Sep-Oct Chem. Phys. Lipids pmid:17583687
Naidu KA et al. P53 enhances ascorbyl stearate-induced G2/M arrest of human ovarian cancer cells. 2007 Nov-Dec Anticancer Res. pmid:18225552
Yu DG et al. Tablets with material gradients fabricated by three-dimensional printing. 2007 J Pharm Sci pmid:17497729
Fatouros DG et al. Clinical studies with oral lipid based formulations of poorly soluble compounds. 2007 Ther Clin Risk Manag pmid:18472981
Kusano M et al. Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. 2007 BMC Syst Biol pmid:18028551
Zhao L et al. Non-destructive determination of metronidazole powder by using artificial neural networks on short-wavelength NIR spectroscopy. 2007 Spectrochim Acta A Mol Biomol Spectrosc pmid:16920000
Maduko CO et al. Enzymatic interesterification of tripalmitin with vegetable oil blends for formulation of caprine milk infant formula analogs. 2007 J. Dairy Sci. pmid:17235135
Graves EL et al. Factors affecting the concentration of sphingomyelin in bovine milk. 2007 J. Dairy Sci. pmid:17235147
Cavallari C et al. Enhanced release of indomethacin from Pvp/stearic acid microcapsules prepared coupling Co-freeze-drying and ultrasound assisted spray-congealing process. 2007 Pharm. Res. pmid:17252191