stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Dermatitis, Contact D003877 59 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Edema D004487 152 associated lipids
Fatty Liver D005234 48 associated lipids
Foreign Bodies D005547 5 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Gonorrhea D006069 7 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Chen DB et al. [In vitro and in vivo study of two kinds of long-circulating solid lipid nanoparticles containing paclitaxel]. 2002 Yao Xue Xue Bao pmid:12579901
Ye YQ et al. [Preparation and characterization of stearic acid-grafted chitosan oligosaccharide polymeric micelles]. 2004 Yao Xue Xue Bao pmid:15491108
Jiang RG et al. [Effect of surface modification on surface energy of lactose and performance of dry powder inhalations]. 2005 Yao Xue Xue Bao pmid:16011271
Chen JM et al. [Comparison of seed oil physicochemical characteristics among three cultivars of Jatropha curcas L]. 2009 Ying Yong Sheng Tai Xue Bao pmid:20353052
Chung DJ et al. Black cohosh and St. John's wort (GYNO-Plus) for climacteric symptoms. 2007 Yonsei Med. J. pmid:17461529
Hatipoglu ON and Tasan Y A comparative efficacy and safety study of clarithromycin, roxithromycin and erythromycin stearate in mild pneumonia. 2000 Yonsei Med. J. pmid:10957888
Schmidt P et al. [Animal experiments on barium stearate toxicity]. 1975 Z Gesamte Hyg pmid:1189478
Schmidt P et al. [Acute inhalation toxicity of cadmium stearate]. 1971 Z Gesamte Hyg pmid:5123074
Murkovic M et al. Variability of fatty acid content in pumpkin seeds (Cucurbita pepo L.). 1996 Z Lebensm Unters Forsch pmid:8873459
Gonzalez-Castro MY et al. Effects of blanching, freezing and freeze-drying on the fatty acid contents of green beans. 1996 Z Lebensm Unters Forsch pmid:9123974
Shani J et al. Efficacy of sustained-release radioprotective drugs in vivo. 1987 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:2966504
Simpson JT et al. Identification of major lipids from the scent gland secretions of Dumeril's ground boa (Acrantophis dumerili Jan) by gas chromatography-mass spectrometry. 1988 Nov-Dec Z. Naturforsch., C, J. Biosci. pmid:3245880
Kraus G et al. [The modification of different element levels in human blood by occupational cadmium exposure]. 1988 Zentralbl Bakteriol Mikrobiol Hyg B pmid:3138836
Kankofer M et al. The analysis of fatty acid content and phospholipase A2 activity in placenta of cows with and without retained fetal membranes. 1996 Zentralbl Veterinarmed A pmid:8940891
el-Naghy MA et al. Fungistatic action of natural oils and fatty acids on dermatophytic and saprophytic fungi. 1992 Zentralbl. Mikrobiol. pmid:1609554
Zakhariv OIa and Ianovich VG [The utilization of [9,10-(3)H] stearic and [1-(14)C] linolenic acids in the in-vitro synthesis of lipids in ruminant tissues]. 1995 Jul-Aug Zh. Evol. Biokhim. Fiziol. pmid:8779280
Wang Y et al. [Analysis of plasma metabonomics of mini-swines with qi deficiency and blood stasis syndrome due to chronic myocardial ischemia]. 2011 Zhong Xi Yi Jie He Xue Bao pmid:21288451
Luan L et al. [Studies on the chemical constituents of extract with water from Forsythia suspensa]. 2010 Zhong Yao Cai pmid:20575415
Cai JY et al. [Studies on chemical constituents from Anoectochilus roxburghii]. 2008 Zhong Yao Cai pmid:18619237
Ma BJ et al. [Chemical constituents study on the fruiting bodies of Lactarius rufus]. 2008 Zhong Yao Cai pmid:18619269