| MeSH term | MeSH ID | Detail |
|---|---|---|
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Foreign Bodies | D005547 | 5 associated lipids |
| Gallbladder Neoplasms | D005706 | 3 associated lipids |
| Gonorrhea | D006069 | 7 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Bergquist SO et al. | Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. | 1987 | Pediatr. Infect. Dis. J. | pmid:2885802 |
| Zara GP et al. | Erythromycin and gastrointestinal motility. | 1987 | Lancet | pmid:2889954 |
| West AA et al. | The relationship between glycosyltransferase production and membrane fatty acid composition of Streptococcus sanguis NCTC 7865 grown in the presence of protonmotive force inhibitors. | 1987 | J. Gen. Microbiol. | pmid:2966234 |
| Ondrias K et al. | Spin label study of the perturbation effect of the local anaesthetics tetracaine and dibucaine on synaptosomes at pharmacological concentrations. | 1987 | Biochem. Pharmacol. | pmid:2825709 |
| Reddy TS and Bazan NG | Arachidonic acid, stearic acid, and diacylglycerol accumulation correlates with the loss of phosphatidylinositol 4,5-bisphosphate in cerebrum 2 seconds after electroconvulsive shock: complete reversion of changes 5 minutes after stimulation. | 1987 | J. Neurosci. Res. | pmid:2830409 |
| Ogata S et al. | Chemical identification of lipid components in the membranous form of rat liver alkaline phosphatase. | 1987 | J. Biochem. | pmid:2834351 |
| Swendsen CL et al. | Human neutrophils incorporate arachidonic acid and saturated fatty acids into separate molecular species of phospholipids. | 1987 | Biochim. Biophys. Acta | pmid:3105590 |
| DeGeorge JJ et al. | Acetylcholine stimulates selective liberation and re-esterification of arachidonate and accumulation of inositol phosphates and glycerophosphoinositol in C62B glioma cells. | 1987 | J. Biol. Chem. | pmid:3110145 |
| Morse DR et al. | Infectious flare-ups and serious sequelae following endodontic treatment: a prospective randomized trial on efficacy of antibiotic prophylaxis in cases of asymptomatic pulpal-periapical lesions. | 1987 | Oral Surg. Oral Med. Oral Pathol. | pmid:3112672 |
| Crost S et al. | Hormonal effects on mitochondrial respiration: potential role of endogenous lipolytic activities. | 1987 | Arch. Biochem. Biophys. | pmid:3113334 |
| Halát G et al. | Effects of incomplete ischemia and subsequent recirculation on free palmitate, stearate, oleate and arachidonate levels in lumbar and cervical spinal cord of rabbit. | 1987 | Gen. Physiol. Biophys. | pmid:3117617 |
| Imai A and Gershengorn MC | Measurement of lipid turnover in response to thyrotropin-releasing hormone. | 1987 | Meth. Enzymol. | pmid:3037241 |
| Feix JB et al. | Interactions of 14N:15N stearic acid spin-label pairs: effects of host lipid alkyl chain length and unsaturation. | 1987 | Biochemistry | pmid:2820479 |
| Roughan PG et al. | Metabolism of exogenous long-chain fatty acids by spinach leaves. | 1987 | Arch. Biochem. Biophys. | pmid:3426240 |
| Rhoads DE et al. | Metabolism of saturated fatty acids by Paramecium tetraurelia. | 1987 | J. Lipid Res. | pmid:3430068 |
| Tonnet ML and Green AG | Characterization of the seed and leaf lipids of high and low linolenic acid flax genotypes. | 1987 | Arch. Biochem. Biophys. | pmid:3813554 |
| Ong DE et al. | Acyl-CoA-independent esterification of retinol bound to cellular retinol-binding protein (type II) by microsomes from rat small intestine. | 1987 | J. Biol. Chem. | pmid:3818619 |
| Berlin E et al. | Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits. | 1987 | Atherosclerosis | pmid:3827974 |
| Albertini G et al. | Studies of structural modifications induced by gamma-irradiation in distearoylphosphatidylcholine liposomes. | 1987 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:3496306 |
| Carter BL et al. | Gastrointestinal side effects with erythromycin preparations. | 1987 | Drug Intell Clin Pharm | pmid:3498618 |
| Seifert R et al. | Activation of protein kinase C by cis- and trans-octadecadienoic acids in intact human platelets and its potentiation by diacylglycerol. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3426598 |
| Bos CE et al. | Native starch in tablet formulations: properties on compaction. | 1987 | Pharm Weekbl Sci | pmid:3432037 |
| Nadai M et al. | [Correlation between in vitro dissolution characteristics of macrolide antibiotic tablets and bioavailability in man]. | 1987 | Yakugaku Zasshi | pmid:3437396 |
| Hasin Y et al. | Dietary lipid intake and myocardial electrophysiology. | 1987 | Isr. J. Med. Sci. | pmid:3440741 |
| Cutler RR et al. | The effect of polyoxyethylene stearate (POES) on the growth of mycobacteria in radiometric 7H12 Middlebrook TB medium. | 1987 | Tubercle | pmid:3448797 |
| Matsui MS and Jeffrey AM | Fatty acid modification of C3H 10T 1/2 fibroblast cells: changes in benzo(a)pyrene metabolism and phorbol ester binding. | 1987 | Cancer Res. | pmid:3471326 |
| Venho VM et al. | The value of comparative bioavailability studies of marketed drugs in drug control. An example with erythromycin stearate. | 1987 | Methods Find Exp Clin Pharmacol | pmid:3683018 |
| Bridges CD et al. | Rhodopsin, vitamin A, and interstitial retinol-binding protein in the rd chicken. | 1987 | Invest. Ophthalmol. Vis. Sci. | pmid:3557867 |
| Hope MJ and Cullis PR | Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. | 1987 | J. Biol. Chem. | pmid:3558410 |
| Husebye ES and Flatmark T | Characterization of phospholipase activities in chromaffin granule ghosts isolated from the bovine adrenal medulla. | 1987 | Biochim. Biophys. Acta | pmid:3607074 |
| Cavalleri A and Minoia C | Lead level of whole blood and plasma in workers exposed to lead stearate. | 1987 | Scand J Work Environ Health | pmid:3616550 |
| Seimiya T et al. | Effects of composition and molecular packing on ionic properties of lipid monolayer having both cationic and anionic head groups. | 1987 | Chem. Phys. Lipids | pmid:3621383 |
| Salminen S and Salminen E | Urinary excretion of orally administered oxalic acid in MYRJ 45-treated NMRI mice. | 1987 | Toxicol. Lett. | pmid:3590233 |
| Masuzawa Y et al. | Distribution of dietary trans-octadecenoate among acyl-CoA and other lipid fractions of rat liver and heart. | 1987 | Biochim. Biophys. Acta | pmid:3593750 |
| Kolesnick RN and Paley AE | 1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action. | 1987 | J. Biol. Chem. | pmid:3597411 |
| Habib NA et al. | Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas. | 1987 | Int J Colorectal Dis | pmid:3598325 |
| Pyörälä S | Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk. | 1987 | J. Vet. Pharmacol. Ther. | pmid:3656512 |
| Emken EA et al. | Metabolism in humans of cis-12,trans-15-octadecadienoic acid relative to palmitic, stearic, oleic and linoleic acids. | 1987 | Lipids | pmid:3306237 |
| Dinman BD | Aluminum in the lung: the pyropowder conundrum. | 1987 | J Occup Med | pmid:3316541 |
| Hattori T et al. | Membrane phospholipid composition and membrane fluidity of human brain tumour: a spin label study. | 1987 | Neurol. Res. | pmid:2883605 |
| Søreide O et al. | Inadequacy of oleic acid in erythrocytes as a marker of malignancies. | 1987 | Br Med J (Clin Res Ed) | pmid:3103770 |
| Kringsholm B and Christoffersen P | The nature and the occurrence of birefringent material in different organs in fatal drug addiction. | 1987 May-Jun | Forensic Sci. Int. | pmid:3036675 |
| Udod VM et al. | [Microbial breakdown of stearox-6 and a study of the genetic determination of the nature of the degradative activity]. | 1987 May-Jun | Mikrobiol. Zh. | pmid:3150493 |
| Shani J et al. | Efficacy of sustained-release radioprotective drugs in vivo. | 1987 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:2966504 |
| Loscalzo J et al. | Unsaturated fatty acids enhance low density lipoprotein uptake and degradation by peripheral blood mononuclear cells. | 1987 Sep-Oct | Arteriosclerosis | pmid:3675304 |
| Hoeg JM et al. | Apolipoprotein B synthesized by Hep G2 cells undergoes fatty acid acylation. | 1988 | J. Lipid Res. | pmid:2846736 |
| Avila P et al. | Which salt of erythromycin is most hepatotoxic? | 1988 | Lancet | pmid:2896928 |
| Jones RE and Plymate SR | Evidence for the regulation of fatty acid utilization in human sperm by docosahexaenoic acid. | 1988 | Biol. Reprod. | pmid:2905175 |
| Van Rafelghem MJ and Andersen ME | The effects of perfluorodecanoic acid on hepatic stearoyl-coenzyme A desaturase and mixed function oxidase activities in rats. | 1988 | Fundam Appl Toxicol | pmid:2906022 |
| Baichwal AR and Augsburger LL | Variations in the friction coefficients of tablet lubricants and relationship to their physicochemical properties. | 1988 | J. Pharm. Pharmacol. | pmid:2907013 |
| Longmuir KJ and Rossi ME | Fatty acid chain-shortening activity in the pulmonary type II cell. | 1988 | Biochim. Biophys. Acta | pmid:3289622 |
| Schmid KM and Patterson GW | Effects of cyclopropenoid fatty acids on fungal growth and lipid composition. | 1988 | Lipids | pmid:3131612 |
| Chu SH and Walker WA | Development of the gastrointestinal mucosal barrier: changes in phospholipid head groups and fatty acid composition of intestinal microvillus membranes from newborn and adult rats. | 1988 | Pediatr. Res. | pmid:3131728 |
| Kaya K and Kusumi T | Isolation and structural characterization of a diacyltaurolipid in cells of Tetrahymena mimbres. | 1988 | Biochim. Biophys. Acta | pmid:3132980 |
| Aho P and Männistö PT | Effects of two erythromycins, doxycycline and phenoxymethylpenicillin on human leucocyte chemotaxis in vitro. | 1988 | J. Antimicrob. Chemother. | pmid:3134323 |
| Kraus G et al. | [The modification of different element levels in human blood by occupational cadmium exposure]. | 1988 | Zentralbl Bakteriol Mikrobiol Hyg B | pmid:3138836 |
| Abbott AA et al. | A prospective randomized trial on efficacy of antibiotic prophylaxis in asymptomatic teeth with pulpal necrosis and associated periapical pathosis. | 1988 | Oral Surg. Oral Med. Oral Pathol. | pmid:3144686 |
| Takenaka T et al. | Effects of arachidonic acid and the other long-chain fatty acids on the membrane currents in the squid giant axon. | 1988 | J. Membr. Biol. | pmid:3147335 |
| Bach R et al. | Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine. | 1988 | Biochemistry | pmid:3166978 |
| Ertel KD and Carstensen JT | Chemical, physical, and lubricant properties of magnesium stearate. | 1988 | J Pharm Sci | pmid:3171951 |
| Effect of dietary stearic acid on plasma cholesterol level. | 1988 | N. Engl. J. Med. | pmid:3173438 | |
| de Groot AC et al. | Cosmetic allergy from stearic acid and glyceryl stearate. | 1988 | Contact Derm. | pmid:3180776 |
| Ricevuti G et al. | Serum, sputum and bronchial concentrations of erythromycin in chronic bronchitis after single and multiple treatments with either propionate-N-acetylcysteinate or stearate erythromycin. | 1988 | Chemotherapy | pmid:3180905 |
| Morasso MI et al. | Effect of mixing on the biopharmaceutical properties of sulfadiazine tablets. | 1988 | Farmaco Prat | pmid:3181415 |
| Korkeala H and Männistö PT | Time course of the antibacterial activity of erythromycin stearate and erythromycin acistrate against two Staphylococcus aureus strains in vitro. | 1988 | J. Antimicrob. Chemother. | pmid:3182415 |
| Demediuk P et al. | Traumatic brain injury in the rat: effects on lipid metabolism, tissue magnesium, and water content. | 1988 | J. Neurotrauma | pmid:3066912 |
| Nahata MC | Selection of an erythromycin for the treatment of pertussis. | 1988 | Drug Intell Clin Pharm | pmid:3069427 |
| Ciszewski A and Lukaszewski Z | Electrochemical masking for removal of the titanium matrix effect in DPASV determination of thallium. | 1988 | Talanta | pmid:18964494 |
| Huang G et al. | Identification of the thiol ester linked lipids in apolipoprotein B. | 1988 | Biochemistry | pmid:3365394 |
| Periquet B et al. | Fatty acid composition and kinetic behaviour of liver retinyl esters in vitamin A sufficient and deficient rats. | 1988 | Clin. Chim. Acta | pmid:3370842 |
| Brodersen R et al. | Palmitate binding to serum albumin, measured by rate of dialysis. | 1988 | Eur. J. Biochem. | pmid:3371363 |
| Slinger AJ and Isaac RE | Synthesis of apolar ecdysone esters by ovaries of the cockroach Periplaneta americana. | 1988 | Gen. Comp. Endocrinol. | pmid:3371652 |
| Roberts L | Beef and chocolate: a partial reprieve. | 1988 | Science | pmid:3375809 |
| Salo OP et al. | Efficacy and tolerability of erythromycin acistrate and erythromycin stearate in acute skin infections of patients with atopic eczema. | 1988 | J. Antimicrob. Chemother. | pmid:3391871 |
| Rostila T et al. | Erythromycin acistrate and erythromycin stearate in the treatment of non-gonococcal urethritis. | 1988 | J. Antimicrob. Chemother. | pmid:3391873 |
| Männistö PT et al. | Fate of single oral doses of erythromycin acistrate, erythromycin stearate and pelleted erythromycin base analysed by mass-spectrometry in plasma of healthy human volunteers. | 1988 | J. Antimicrob. Chemother. | pmid:3391874 |
| Savolainen S et al. | Tonsillar penetration of erythromycin and its 2'-acetyl ester in patients with chronic tonsillitis. | 1988 | J. Antimicrob. Chemother. | pmid:3391878 |
| Viluksela M et al. | Comparative liver toxicity of various erythromycin derivatives in animals. | 1988 | J. Antimicrob. Chemother. | pmid:3391880 |
| Ogata S et al. | Chemical characterization of the membrane-anchoring domain of human placental alkaline phosphatase. | 1988 | J. Biol. Chem. | pmid:3392021 |
| Pitt WG and Cooper SL | Albumin adsorption on alkyl chain derivatized polyurethanes: I. The effect of C-18 alkylation. | 1988 | J. Biomed. Mater. Res. | pmid:3397377 |
| Rahman MD et al. | Effects of sulfur-containing analogues of stearic acid on growth and fatty acid biosynthesis in the protozoan Crithidia fasciculata. | 1988 | J. Med. Chem. | pmid:3398003 |
| Trinchera M et al. | Different metabolic recycling of the lipid components of exogenous sulphatide in human fibroblasts. | 1988 | Biochem. J. | pmid:3415659 |
| Bull AW et al. | Structural requirements for stimulation of colonic cell proliferation by oxidized fatty acids. | 1988 | Cancer Res. | pmid:3349456 |
| Sanjurjo P et al. | Plasma fatty acid composition during the first week of life following feeding with human milk or formula. | 1988 | Acta Paediatr Scand | pmid:3354331 |
| Graham A et al. | Fatty acid specificity for the synthesis of triacylglycerol and phosphatidylcholine and for the secretion of very-low-density lipoproteins and lysophosphatidylcholine by cultures of rat hepatocytes. | 1988 | Biochem. J. | pmid:3355493 |
| Bonanome A and Grundy SM | Effect of dietary stearic acid on plasma cholesterol and lipoprotein levels. | 1988 | N. Engl. J. Med. | pmid:3362176 |
| Rosenberg IH and Schaefer EJ | Dietary saturated fatty acids and blood cholesterol. | 1988 | N. Engl. J. Med. | pmid:3362180 |
| Cevc G et al. | Phosphatidylcholine-fatty acid membranes. I. Effects of protonation, salt concentration, temperature and chain-length on the colloidal and phase properties of mixed vesicles, bilayers and nonlamellar structures. | 1988 | Biochim. Biophys. Acta | pmid:2835979 |
| Zanetti R and Catalá A | Lipid binding properties of fatty acid binding protein isolated from mouse liver. | 1988 | Acta Physiol Pharmacol Latinoam | pmid:3201993 |
| Nakayoshi T et al. | Comparative study on effects of 14- and 16-membered macrolides on gastrointestinal motility in unanaesthetized dogs. | 1988 | Drugs Exp Clin Res | pmid:3265375 |
| Yeh YY | Long chain fatty acid deficits in brain myelin sphingolipids of undernourished rat pups. | 1988 | Lipids | pmid:3226227 |
| Broderick PA | Distinguishing in vitro electrochemical signatures for norepinephrine and dopamine. | 1988 | Neurosci. Lett. | pmid:3226613 |
| Ubels JL et al. | Vitamin A is stored as fatty acyl esters of retinol in the lacrimal gland. | 1988 | Curr. Eye Res. | pmid:3229120 |
| McNulty CA et al. | Inhibitory antimicrobial concentrations against Campylobacter pylori in gastric mucosa. | 1988 | J. Antimicrob. Chemother. | pmid:3209531 |
| Tan S et al. | Gas chromatographic determination of calcium stearate in polyethylene food packaging sheets. | 1988 | J. Chromatogr. | pmid:3209663 |
| Sparace SA et al. | A preliminary analysis of Fatty Acid synthesis in pea roots. | 1988 | Plant Physiol. | pmid:16666088 |
| Horváth LI et al. | Exchange rates at the lipid-protein interface of myelin proteolipid protein studied by spin-label electron spin resonance. | 1988 | Biochemistry | pmid:2450570 |
| Heyman SN et al. | Erythromycin-induced dynamic ileus? | 1988 | J. Clin. Gastroenterol. | pmid:3183328 |
| Hoppe JE and Haug A | Treatment and prevention of pertussis by antimicrobial agents (Part II). | 1988 May-Jun | Infection | pmid:3042626 |
| Simpson JT et al. | Identification of major lipids from the scent gland secretions of Dumeril's ground boa (Acrantophis dumerili Jan) by gas chromatography-mass spectrometry. | 1988 Nov-Dec | Z. Naturforsch., C, J. Biosci. | pmid:3245880 |