| MeSH term | MeSH ID | Detail |
|---|---|---|
| Foreign Bodies | D005547 | 5 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| MuselÃk J et al. | Influence of process parameters on content uniformity of a low dose active pharmaceutical ingredient in a tablet formulation according to GMP. | 2014 | Acta Pharm | pmid:25296681 |
| Tsukada G et al. | Temperature triggered shape memory effect of transpolyisoprene-based polymer. | 2014 | J Endod | pmid:25260740 |
| Haware RV et al. | Application of multivariate methods to evaluate the functionality of bovine- and vegetable-derived magnesium stearate. | 2014 | J Pharm Sci | pmid:24596131 |
| Guo H et al. | In vitro and in vivo study of Gal-OS self-assembled nanoparticles for liver-targeting delivery of doxorubicin. | 2014 | J Pharm Sci | pmid:24549734 |
| Rico JE et al. | Compared with stearic acid, palmitic acid increased the yield of milk fat and improved feed efficiency across production level of cows. | 2014 | J. Dairy Sci. | pmid:24342689 |
| Petridis L et al. | Spatial arrangement of organic compounds on a model mineral surface: implications for soil organic matter stabilization. | 2014 | Environ. Sci. Technol. | pmid:24328330 |
| Maghsoodi M | Floating-pulsatile release multiparticulate system for chronopharmacotherapy: effect of some hydrophobic additives on the buoyancy and release behavior of particles. | 2014 | Drug Res (Stuttg) | pmid:23950100 |
| Gouk SW et al. | Stearic acids at sn-1, 3 positions of TAG are more efficient at limiting fat deposition than palmitic and oleic acids in C57BL/6 mice. | 2014 | Br. J. Nutr. | pmid:24286356 |
| Carrero-Colón M et al. | Mutations in SACPD-C result in a range of elevated stearic acid concentration in soybean seed. | 2014 | PLoS ONE | pmid:24846334 |
| Gebauer SK et al. | Impact of stearic acid and oleic acid on hemostatic factors in the context of controlled diets consumed by healthy men. | 2014 | Eur J Clin Nutr | pmid:24736679 |
| Liau CP et al. | Preparation and characterization of polyhydroxybutyrate/polycaprolactone nanocomposites. | 2014 | ScientificWorldJournal | pmid:24600329 |
| Woo JO et al. | Development of a controlled release of salicylic acid loaded stearic acid-oleic acid nanoparticles in cream for topical delivery. | 2014 | ScientificWorldJournal | pmid:24578624 |
| Yee JK et al. | High oleic/stearic fatty-acid desaturation index in cord plasma from infants of mothers with gestational diabetes. | 2014 | J Perinatol | pmid:24577432 |
| Aznar-Moreno JA et al. | Sunflower (Helianthus annuus) long-chain acyl-coenzyme A synthetases expressed at high levels in developing seeds. | 2014 | Physiol Plant | pmid:24102504 |
| Huang FC et al. | Expression and characterization of CYP52 genes involved in the biosynthesis of sophorolipid and alkane metabolism from Starmerella bombicola. | 2014 | Appl. Environ. Microbiol. | pmid:24242247 |
| Sassa T et al. | Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid. | 2014 | J. Lipid Res. | pmid:24489110 |
| Liu J et al. | Saturated fatty acids up-regulate COX-2 expression in prostate epithelial cells via toll-like receptor 4/NF-κB signaling. | 2014 | Inflammation | pmid:24221358 |
| Kushner J et al. | A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes. | 2014 | J Pharm Sci | pmid:24375069 |
| Dou J et al. | Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration. | 2014 | Colloids Surf B Biointerfaces | pmid:24157590 |
| Meulenaar J et al. | Development of an extended-release formulation of capecitabine making use of in vitro-in vivo correlation modelling. | 2014 | J Pharm Sci | pmid:24311366 |