stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Foreign Bodies D005547 5 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Arteriosclerosis D001161 86 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Stanisz B et al. Effect of pharmaceutical excipients on the stability of angiotensin-converting enzyme inhibitors in their solid dosage formulations. 2013 Drug Dev Ind Pharm pmid:22348774
Saeedi Vahdat A et al. Ultrasonic approach for viscoelastic and microstructure characterization of granular pharmaceutical tablets. 2013 Int J Pharm pmid:23820132
Franc A et al. [Content uniformity of warfarin-containing mixtures and tablets]. 2013 Ceska Slov Farm pmid:24047147
Li L et al. Drug release characteristics from chitosan-alginate matrix tablets based on the theory of self-assembled film. 2013 Int J Pharm pmid:23624081
Mužíková J and Sináglová P A study of a new co-processed dry binder based on spray-dried lactose and microcrystalline cellulose. 2013 Ceska Slov Farm pmid:23961814
Neutsch L et al. UPEC biomimickry at the urothelial barrier: lectin-functionalized PLGA microparticles for improved intravesical chemotherapy. 2013 Int J Pharm pmid:23628404
Emken E Human studies using isotope labeled fatty acids: answered and unanswered questions. 2013 J Oleo Sci pmid:23648399
Zhou X et al. The effect of saturated fatty acids on methanogenesis and cell viability of Methanobrevibacter ruminantium. 2013 Archaea pmid:23710130
Silberstein T et al. Saturated fatty acid composition of human milk in Israel: a comparison between Jewish and Bedouin women. 2013 Isr. Med. Assoc. J. pmid:23781748
Nakagawa H et al. Real-time monitoring of lubrication properties of magnesium stearate using NIR spectrometer and thermal effusivity sensor. 2013 Int J Pharm pmid:23174413
Otsuka Y et al. Effects of polymorphic transformation on pharmaceutical properties of direct compressed tablets containing theophylline anhydrate bulk powder under high humidity. 2013 Colloids Surf B Biointerfaces pmid:23178204
Azordegan N et al. Carcinogenesis alters fatty acid profile in breast tissue. 2013 Mol. Cell. Biochem. pmid:23180247
Delbecq F et al. N-stearoyl amino acid derivatives: potent biomimetic hydro/organogelators as templates for preparation of gold nanoparticles. 2013 J Colloid Interface Sci pmid:23089597
Cunha TA et al. Effect of stearic acid on enalapril stability and dissolution from multiparticulate solid dosage forms. 2013 AAPS PharmSciTech pmid:23897034
Jaumot J et al. Blending process modeling and control by multivariate curve resolution. 2013 Talanta pmid:24209372
Uchimoto T et al. Determination of useful ranges of mixing conditions for glycerin Fatty Acid ester by multiple regression analysis. 2013 Chem. Pharm. Bull. pmid:24189302
Høstmark AT et al. Increased serum triglycerides and reduced HDL cholesterol in male rats after intake of ammonium chloride for 3 weeks. 2013 Lipids Health Dis pmid:23800210
Saroja C and Lakshmi PK Formulation and optimization of fenofibrate lipospheres using Taguchi's experimental design. 2013 Acta Pharm pmid:23482314
Pethrick RA and Song M Dielectric studies of amylose, amylopectin and amylose-stearic acid complexes. 2013 Carbohydr Polym pmid:23399185
Subbaramaiah K et al. Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. 2013 Cancer Prev Res (Phila) pmid:23880231