stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Foreign Bodies D005547 5 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Uterine Neoplasms D014594 18 associated lipids
Adrenoleukodystrophy D000326 29 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Arteriosclerosis D001161 86 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Dawes J et al. Application of external lubrication during the roller compaction of adhesive pharmaceutical formulations. 2013 Pharm Dev Technol pmid:22813432
Mazel V et al. The surface layer of pharmaceutical compacts: the role of the punch surface and its impact on the mechanical properties of the compacts. 2013 Int J Pharm pmid:22902389
Intorre F et al. Fatty acid content of serum lipid fractions and blood lipids in normolipidaemic volunteers fed two types of cheese having different fat compositions: a pilot study. 2013 Int J Food Sci Nutr pmid:22849318
Dangarembizi R et al. Aloe ferox seed: a potential source of oil for cosmetic and pharmaceutical use. 2013 Nat Prod Commun pmid:23678824
Maia M et al. A novel, direct, reagent-free method for the detection of beeswax adulteration by single-reflection attenuated total reflectance mid-infrared spectroscopy. 2013 Talanta pmid:23598195
Li CC et al. [In situ rat intestine absorption of paclitaxel-loaded solid lipid nanoparticles modified with cell-penetrating peptides]. 2013 Yao Xue Xue Bao pmid:23600154
Salehi M et al. Debinding mechanisms in thermoplastic processing of a Ba(0.5)Sr(0.5)Co(0.8)Fe(0.2)O(3-δ)- stearic acid-polystyrene mixture. 2013 ChemSusChem pmid:23281298
He M et al. Controllable stearic acid crystal induced high hydrophobicity on cellulose film surface. 2013 ACS Appl Mater Interfaces pmid:23289586
Chen JJ et al. New pterosin sesquiterpenes and antitubercular constituents from Pteris ensiformis. 2013 Chem. Biodivers. pmid:24130033
Avalle P et al. Interrogating erosion-based drug liberation phenomena from hydrophilic matrices using near infrared (NIR) spectroscopy. 2013 Eur J Pharm Sci pmid:23059372
Desai SS et al. Methods for reduction of cohesive forces between carrier and drug in DPI formulation. 2013 Drug Dev Ind Pharm pmid:23050727
Vijayaraghavan M et al. Suitability of polymer materials for production of pulmonary microparticles using a PGSS supercritical fluid technique: preparation of microparticles using PEG, fatty acids and physical or chemicals blends of PEG and fatty acids. 2013 Int J Pharm pmid:23178217
Sharma P et al. Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site. 2013 Arch. Biochem. Biophys. pmid:23149273
Tsuchiya A et al. Stearic acid serves as a potent inhibitor of protein tyrosine phosphatase 1B. 2013 Cell. Physiol. Biochem. pmid:24296476
Camacho-Chab JC et al. Emulsifying activity and stability of a non-toxic bioemulsifier synthesized by Microbacterium sp. MC3B-10. 2013 Int J Mol Sci pmid:24065097
Šašiċ S et al. Raman chemical mapping of magnesium stearate delivered by a punch-face lubrication system on the surface of placebo and active tablets. 2013 Appl Spectrosc pmid:24067639
Mérian J et al. Synthetic lipid nanoparticles targeting steroid organs. 2013 J. Nucl. Med. pmid:24071507
Liu Z et al. Changes in the electron paramagnetic resonance spectra of albumin-associated spin-labeled stearic acid as a diagnostic parameter of colorectal cancer. 2013 World J Surg Oncol pmid:24025321
Osorio JG and Muzzio FJ Effects of powder flow properties on capsule filling weight uniformity. 2013 Drug Dev Ind Pharm pmid:23902366
Yuan B et al. Laboratory-scale column study for remediation of TCE-contaminated aquifers using three-section controlled-release potassium permanganate barriers. 2013 J Environ Sci (China) pmid:24218827