| MeSH term | MeSH ID | Detail |
|---|---|---|
| Foreign Bodies | D005547 | 5 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Uterine Neoplasms | D014594 | 18 associated lipids |
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Drug Hypersensitivity | D004342 | 20 associated lipids |
| Arteriosclerosis | D001161 | 86 associated lipids |
stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with stearic acid?
stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with stearic acid
PubChem Associated disorders and diseases
What pathways are associated with stearic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with stearic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with stearic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with stearic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with stearic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with stearic acid?
Knock-out
Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with stearic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Maphalla TG and Emmambux MN | Functionality of maize, wheat, teff and cassava starches with stearic acid and xanthan gum. | 2016 | Carbohydr Polym | pmid:26572436 |
| Du J and Li L | Which one performs better for targeted lung cancer combination therapy: pre- or post-bombesin-decorated nanostructured lipid carriers? | 2016 | Drug Deliv | pmid:26455787 |
| Kumar Gaur P et al. | Nanovesicles of nitrendipine with lipid complex for transdermal delivery: pharmacokinetic and pharmacodynamic studies. | 2016 | Artif Cells Nanomed Biotechnol | pmid:26375758 |
| Ocloo FCK et al. | Effects of stearic acid and gamma irradiation, alone and in combination, on pasting properties of high amylose maize starch. | 2016 | Food Chem | pmid:26212935 |
| Yan G et al. | Preparation and evaluation of liver-targeting micelles loaded with oxaliplatin. | 2016 | Artif Cells Nanomed Biotechnol | pmid:25287740 |
| Pradhan M et al. | Influence of selected variables on fabrication of Triamcinolone acetonide loaded solid lipid nanoparticles for topical treatment of dermal disorders. | 2016 | Artif Cells Nanomed Biotechnol | pmid:25229831 |
| Martins AB and Santana RM | Effect of carboxylic acids as compatibilizer agent on mechanical properties of thermoplastic starch and polypropylene blends. | 2016 | Carbohydr Polym | pmid:26453854 |
| Simon C et al. | Screening of endocrine activity of compounds migrating from plastic baby bottles using a multi-receptor panel of in vitro bioassays. | 2016 | Toxicol In Vitro | pmid:27633901 |
| Jeyanathan J et al. | Biohydrogenation of 22:6n-3 by Butyrivibrio proteoclasticus P18. | 2016 | BMC Microbiol. | pmid:27283157 |
| Hashemi Goradel N et al. | Improvement of Liver Cell Therapy in Rats by Dietary Stearic Acid. | 2016 | Iran. Biomed. J. | pmid:27090202 |
| Ma Y et al. | Silymarin-Loaded Nanoparticles Based on Stearic Acid-Modified Bletilla striata Polysaccharide for Hepatic Targeting. | 2016 | Molecules | pmid:26938513 |
| Šrámek J et al. | p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells. | 2016 | Int J Mol Sci | pmid:26861294 |
| Cerf ME and Herrera E | High Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat. | 2016 | Nutrients | pmid:26742067 |
| Fretts AM et al. | Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. | 2016 | J. Nutr. | pmid:26701797 |
| Sergeant S et al. | Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans. | 2016 | Br. J. Nutr. | pmid:26615716 |
| Nie H et al. | Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in Solid-State Formulations. | 2016 | Mol. Pharm. | pmid:27542728 |
| Passerini N et al. | Development of microparticles for oral administration of the non-conventional radical scavenger IAC and testing in an inflammatory rat model. | 2016 | Int J Pharm | pmid:27530293 |
| Karthik S et al. | Quillaja saponin: A prospective emulsifier for the preparation of solid lipid nanoparticles. | 2016 | Colloids Surf B Biointerfaces | pmid:27521748 |
| Ghate VM et al. | Nanostructured lipid carriers for the topical delivery of tretinoin. | 2016 | Eur J Pharm Biopharm | pmid:27519827 |
| Ohiri RC and Bassey EE | Gas Chromatography-Mass Spectrometry Analysis of Constituent Oil from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), from Nigeria. | 2016 | Int J Med Mushrooms | pmid:27481303 |
| Monteyne T et al. | Stearic acid and high molecular weight PEO as matrix for the highly water soluble metoprolol tartrate in continuous twin-screw melt granulation. | 2016 | Int J Pharm | pmid:27452420 |
| Ariyasu A et al. | Delay effect of magnesium stearate on tablet dissolution in acidic medium. | 2016 | Int J Pharm | pmid:27444551 |
| Schulze C et al. | A one-stage cultivation process for lipid- and carbohydrate-rich biomass of Scenedesmus obtusiusculus based on artificial and natural water sources. | 2016 | Bioresour. Technol. | pmid:27394996 |
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| Yang D et al. | Delivery of siRNA Using Cationic Liposomes Incorporating Stearic Acid-modified Octa-Arginine. | 2016 | Anticancer Res. | pmid:27354583 |
| Liu H et al. | Self-assembled dual-modality contrast agents for non-invasive stem cell tracking via near-infrared fluorescence and magnetic resonance imaging. | 2016 | J Colloid Interface Sci | pmid:27299677 |
| Démuth B et al. | Lubricant-Induced Crystallization of Itraconazole From Tablets Made of Electrospun Amorphous Solid Dispersion. | 2016 | J Pharm Sci | pmid:27290626 |
| Meng T et al. | A spermine conjugated stearic acid-g-chitosan oligosaccharide polymer with different types of amino groups for efficient p53 gene therapy. | 2016 | Colloids Surf B Biointerfaces | pmid:27289311 |
| Schrank S et al. | Pore blocking: An innovative formulation strategy for the design of alcohol resistant multi-particulate dosage forms. | 2016 | Int J Pharm | pmid:27282540 |
| Eltayeb M et al. | Electrosprayed nanoparticle delivery system for controlled release. | 2016 | Mater Sci Eng C Mater Biol Appl | pmid:27207047 |
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| Michaut A et al. | A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen. | 2016 | Toxicol. Appl. Pharmacol. | pmid:26739624 |
| Stahlberg S et al. | Probing the Role of Ceramide Headgroup Polarity in Short-Chain Model Skin Barrier Lipid Mixtures by ²H Solid-State NMR Spectroscopy. | 2016 | Langmuir | pmid:26828109 |
| Lavergne SN et al. | Potential cutaneous hypersensitivity reaction to an inactive ingredient of thyroid hormone supplements in a dog. | 2016 | Vet. Dermatol. | pmid:26748887 |
| Baig MS et al. | Application of Box-Behnken design for preparation of levofloxacin-loaded stearic acid solid lipid nanoparticles for ocular delivery: Optimization, in vitro release, ocular tolerance, and antibacterial activity. | 2016 | Int. J. Biol. Macromol. | pmid:26740466 |
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| Wood MH et al. | Comparative Adsorption of Saturated and Unsaturated Fatty Acids at the Iron Oxide/Oil Interface. | 2016 | Langmuir | pmid:26707597 |
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| Castellanos-Tapia L et al. | Apolipoprotein E isoforms 3/3 and 3/4 differentially interact with circulating stearic, palmitic, and oleic fatty acids and lipid levels in Alaskan Natives. | 2015 | Nutr Res | pmid:25727313 |
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