stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Lymphadenitis D008199 8 associated lipids
Lymphoma D008223 18 associated lipids
Lymphoma, Non-Hodgkin D008228 6 associated lipids
Malignant Hyperthermia D008305 6 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Melanoma D008545 69 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Neuroblastoma D009447 66 associated lipids
Occupational Diseases D009784 42 associated lipids
Otitis Media D010033 12 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Pneumoconiosis D011009 3 associated lipids
Eczema, Dyshidrotic D011146 1 associated lipids
Prostatic Diseases D011469 4 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Relapsing Fever D012061 3 associated lipids
Rosacea D012393 13 associated lipids
Salivary Duct Calculi D012465 2 associated lipids
Seizures D012640 87 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
LEFEBVRE P and HENRIOUL F [INFLUENCE OF GLUCAGON ON THE BLOOD LEVEL AND ARTERIO-VENOUS DIFFERENCE OF UNESTERIFIED FATTY ACIDS]. 1963 Sep-Oct Ann. Endocrinol. (Paris) pmid:14092350
BLOMSTRAND R et al. BIOHYDROGENATION IN GERM-FREE RATS. 1963 Jul-Aug J Atheroscler Res pmid:14051792
ULLMANN E et al. [STUDIES ON THE STABILITY OF PENICILLIN G SODIUM IN THE PRESENCE OF IONOGENIC TENSIDES, ORGANIC GEL FORMERS AND PRESERVATIVE AGENTS. 7. COMMUNICATION ON THE INFLUENCE OF ADJUVANTS IN DRUG COMPOUNDING]. 1963 Jul-Aug Pharm Acta Helv pmid:14052353
MORRIS LJ SEPARATION OF ISOMERIC LONG-CHAIN POLYHYDROXY ACIDS BY THIN-LAYER CHROMATOGRAPHY. 1963 J. Chromatogr. pmid:14070998
SHIFRINE M and MARR AG THE REQUIREMENT OF FATTY ACIDS BY PITYROSPORUM OVALE. 1963 J. Gen. Microbiol. pmid:14053273
SOLOFF LA and WIEDEMAN MP BIOMICROSCOPIC OBSERVATIONS ON VASOCONSTRICTIVE AND THROMBOGENIC EFFECTS PRODUCED BY LONG-CHAIN SATURATED FATTY ACIDS WITHIN THE VASCULATURE OF THE WING OF AN UNANAESTHETIZED BAT. 1963 Nature pmid:14058613
ROUS S and FAVARGER P [ROLE OF DEGRADATION IN THE MAINTENANCE OF THE COMPOSITION OF RESERVE FATTY ACIDS]. 1963 Helv Physiol Pharmacol Acta pmid:14058926
GOMPERTZ SM and SAMMONS HG THE ORIGIN OF FAECAL LIPIDS. THE COMPOSITION OF FAECAL FATSIN HUMAN SUBJECTS. 1963 Clin. Chim. Acta pmid:14063975
DEMPSKI RE et al. Permeability of excised human keratin to lipid-soluble substances. II. 1963 J Pharm Sci pmid:14026933
KAUNITZ H et al. Studies of the generalized Shwartzman reaction produced by diet. IV. Ethyl ester fractions of cod liver oil and dihydroxystearic acid. 1963 Metab. Clin. Exp. pmid:14031428
WELD JT et al. Production of octadecenoic acid in plasma by Staphylococcus aureus. 1963 Proc. Soc. Exp. Biol. Med. pmid:13999824
ROSENBERG MD Cell guidance by alterations in monomolecular films. 1963 Science pmid:13974905
KUNUGI K Studies on the syntheses of sucrose fatty acid esters. II. Separation of the alcoholyses products by liquid column chromatography and determination of the contents of sucrose monostearate. 1963 Chem. Pharm. Bull. pmid:13927387
KUNUGI K Studies on the syntheses of sucrose fatty acid esters. III. Re-esterification of sucrose monostearate. 1963 Chem. Pharm. Bull. pmid:13927388
NAKAGAKI M and NISHINO M [Studies on the physicochemical properties of aluminum soap. II. Structural viscosity of aluminum stearate in benzene]. 1963 Yakugaku Zasshi pmid:13937343
OSTWALD R Fat content and fatty acids in some commercial mixes for baked products. 1963 J Am Diet Assoc pmid:13940620
HIRSCH J FACTICE CHROMATOGRAPHY: AN AUTOMATICALLY MONITORED, LIQUID-GEL SYSTEM FOR THE SEPARATION OF NONPOLAR LIPIDS. 1963 J. Lipid Res. pmid:14167659
RAZIN S and ROTTEM S FATTY ACID REQUIREMENTS OF MYCOPLASMA LAIDLAWII. 1963 J. Gen. Microbiol. pmid:14114935
HJORTH N and TROLLE-LASSEN C SKIN REACTIONS TO OINTMENT BASES. 1963 Trans St Johns Hosp Dermatol Soc pmid:14116129
CALI G et al. [GAS CHROMATOGRAPHY RESEARCH ON THE FATTY ACIDS OF HUMAN ADIPOSE TISSUE]. 1963 Ric Sci 2 Ser Pt 2 Rend B pmid:14123061