stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Gonorrhea D006069 7 associated lipids
Gallbladder Neoplasms D005706 3 associated lipids
Foreign Bodies D005547 5 associated lipids
Fatty Liver D005234 48 associated lipids
Edema D004487 152 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Dermatitis, Contact D003877 59 associated lipids
Dermatitis D003872 30 associated lipids
Decalcification, Pathologic D003649 1 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Coronary Disease D003327 70 associated lipids
Chancroid D002602 4 associated lipids
Ischemic Attack, Transient D002546 42 associated lipids
Brain Ischemia D002545 89 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Cattle Diseases D002418 24 associated lipids
Per page 10 20 50 100 | Total 101

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Samanta AK et al. Cone milling of compacted flakes: process parameter selection by adopting the minimal fines approach. 2012 Int J Pharm pmid:22001841
Tay T et al. Dissolution of a poorly water-soluble drug dry coated with magnesium and sodium stearate. 2012 Eur J Pharm Biopharm pmid:22036990
Abe H and Otsuka M Effects of lubricant-mixing time on prolongation of dissolution time and its prediction by measuring near infrared spectra from tablets. 2012 Drug Dev Ind Pharm pmid:21954869
Zanon NC et al. Immbolization of uricase enzyme in Langmuir and Langmuir-Blodgett films of fatty acids: possible use as a uric acid sensor. 2012 J Colloid Interface Sci pmid:21875709
Sabir A et al. The fatty acid and tocopherol constituents of the seed oil extracted from 21 grape varieties (Vitis spp.). 2012 J. Sci. Food Agric. pmid:22271548
Vega Mercado F et al. Modulation of the domain topography of biphasic monolayers of stearic acid and dimyristoyl phosphatidylcholine. 2012 Chem. Phys. Lipids pmid:22274694
Mason P et al. SCD1 inhibition causes cancer cell death by depleting mono-unsaturated fatty acids. 2012 PLoS ONE pmid:22457791
Morales A et al. Quantitative analysis of hydroperoxy-, keto- and hydroxy-dienes in refined vegetable oils. 2012 J Chromatogr A pmid:22321954
Olivieri C et al. Phylogenetic position of a copper age sheep (Ovis aries) mitochondrial DNA. 2012 PLoS ONE pmid:22457789
Liu X et al. Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. 2012 PLoS Pathog. pmid:22412372
Lee AL and Kim CB The effect of erythromycin on gastrointestinal motility in subtotal gastrectomized patients. 2012 J Korean Surg Soc pmid:22403748
Sampey BP et al. Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. 2012 PLoS ONE pmid:22701716
Singh AV and Nath LK Evaluation of acetylated moth bean starch as a carrier for controlled drug delivery. 2012 Int. J. Biol. Macromol. pmid:22210486
Basseri S and Austin RC Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential. 2012 Biochem Res Int pmid:22195283
Seeliger JC et al. Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. 2012 J. Biol. Chem. pmid:22194604
Hao J et al. Development and optimization of baicalin-loaded solid lipid nanoparticles prepared by coacervation method using central composite design. 2012 Eur J Pharm Sci pmid:22820033
Severino P et al. Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. 2012 J Drug Deliv pmid:22175030
Han K et al. Novel gene transfer vectors based on artificial recombinant multi-functional oligopeptides. 2012 Int J Pharm pmid:22796172
Kottala N et al. Influence of compaction properties and interfacial topography on the performance of bilayer tablets. 2012 Int J Pharm pmid:22728259
Chansela P et al. Composition and localization of lipids in Penaeus merguiensis ovaries during the ovarian maturation cycle as revealed by imaging mass spectrometry. 2012 PLoS ONE pmid:22432001
Kakisaka K et al. Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21995961
Galvao TF et al. High intake of saturated fat, but not polyunsaturated fat, improves survival in heart failure despite persistent mitochondrial defects. 2012 Cardiovasc. Res. pmid:21960686
Honkanen AM et al. Characterization of the disappearance and formation of biohydrogenation intermediates during incubations of linoleic acid with rumen fluid in vitro. 2012 J. Dairy Sci. pmid:22365221
Kushner J Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume. 2012 Int J Pharm pmid:22405966
Matsui H et al. Stearoyl-CoA desaturase-1 (SCD1) augments saturated fatty acid-induced lipid accumulation and inhibits apoptosis in cardiac myocytes. 2012 PLoS ONE pmid:22413010
Zhang ZH et al. Solid lipid nanoparticles modified with stearic acid-octaarginine for oral administration of insulin. 2012 Int J Nanomedicine pmid:22848162
Liu J et al. Stearoyl-acyl carrier protein desaturase gene from the oleaginous microalga Chlorella zofingiensis: cloning, characterization and transcriptional analysis. 2012 Planta pmid:22855030
Carol D et al. Synergistic effect of calcium stearate and photo treatment on the rate of biodegradation of low density polyethylene spent saline vials. 2012 Indian J. Exp. Biol. pmid:22822530
Serra Bonvehi J and Orantes Bermejo FJ Detection of adulterated commercial Spanish beeswax. 2012 Food Chem pmid:26434344
Lou CW et al. PLA/ β-TCP complex tubes: the mechanical properties and applications of artificial bone. 2012 J Biomater Sci Polym Ed pmid:21968651
Varshosaz J et al. Optimization of self-assembling properties of fatty acids grafted to methoxy poly(ethylene glycol) as nanocarriers for etoposide. 2012 Acta Pharm pmid:22472447
Lee SH et al. End point determination of blending process for trimebutine tablets using principle component analysis (PCA) and partial least squares (PLS) regression. 2012 Arch. Pharm. Res. pmid:23054717
Osmond G et al. Metal stearate distributions in modern artists' oil paints: surface and cross-sectional investigation of reference paint films using conventional and synchrotron infrared microspectroscopy. 2012 Appl Spectrosc pmid:23031696
McNamee CE et al. Effect of the degree of dissociation of molecules in a monolayer at an air/water interface on the force between the monolayer and a like-charged particle in the subphase. 2012 J Phys Chem B pmid:23092192
Chu BB et al. [XANES study of lead speciation in duckweed]. 2012 Guang Pu Xue Yu Guang Pu Fen Xi pmid:23016367
Sharma P et al. Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. 2012 J Biomed Nanotechnol pmid:23030001
Pijls BG et al. Differences in long-term fixation between mobile-bearing and fixed-bearing knee prostheses at ten to 12 years' follow-up: a single-blinded randomised controlled radiostereometric trial. 2012 J Bone Joint Surg Br pmid:23015562
Charpentier PA et al. Nano-TiO2/polyurethane composites for antibacterial and self-cleaning coatings. 2012 Nanotechnology pmid:23037881
Akinsete JA et al. Consumption of high ω-3 fatty acid diet suppressed prostate tumorigenesis in C3(1) Tag mice. 2012 Carcinogenesis pmid:22045025
Baldwin AC et al. A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell death. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22436701
Tuli RA et al. Polycaprolactone microspheres as carriers for dry powder inhalers: effect of surface coating on aerosolization of salbutamol sulfate. 2012 J Pharm Sci pmid:21956254
Shuhendler AJ et al. Thermally-triggered 'off-on-off' response of gadolinium-hydrogel-lipid hybrid nanoparticles defines a customizable temperature window for non-invasive magnetic resonance imaging thermometry. 2012 J Control Release pmid:21939700
Wang X et al. Volatile components of ethanolic extract from broccolini leaves. 2012 Nat. Prod. Res. pmid:21859369
Suo T et al. Fixed-point and stratified analysis of the fine structure and composition of five gallstones with Fourier transform infrared (FT-IR) specular reflection spectroscopy. 2012 Microsc. Res. Tech. pmid:21809418
Smathers RL et al. Characterization of 4-HNE modified L-FABP reveals alterations in structural and functional dynamics. 2012 PLoS ONE pmid:22701647
Foster SP and Anderson KG Synthetic rates of key stored fatty acids in the biosynthesis of sex pheromone in the moth Heliothis virescens. 2012 Insect Biochem. Mol. Biol. pmid:22982110
Xie J et al. Composition of fatty oils from semen ziziphi spinosae and its cardiotonic effect on isolated toad hearts. 2012 Nat. Prod. Res. pmid:21707231
Tamokou Jde D et al. Antioxidant and antimicrobial activities of ethyl acetate extract, fractions and compounds from stem bark of Albizia adianthifolia (Mimosoideae). 2012 BMC Complement Altern Med pmid:22809287
Wang L et al. Effect of rare Earth ions on the properties of composites composed of ethylene vinyl acetate copolymer and layered double hydroxides. 2012 PLoS ONE pmid:22693627
Wong RH et al. Chronic effects of a wild green oat extract supplementation on cognitive performance in older adults: a randomised, double-blind, placebo-controlled, crossover trial. 2012 Nutrients pmid:22690320