stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with stearic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with stearic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with stearic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with stearic acid

Download all related citations
Per page 10 20 50 100 | Total 3506
Authors Title Published Journal PubMed Link
Stinton LM and Shaffer EA Epidemiology of gallbladder disease: cholelithiasis and cancer. 2012 Gut Liver pmid:22570746
Vinay KB et al. Spectrophotometric Determination of Mycophenolate Mofetil as Its Charge-Transfer Complexes with Two π-Acceptors. 2012 J Anal Methods Chem pmid:22567572
Li D et al. Ruminal microbe of biohydrogenation of trans-vaccenic acid to stearic acid in vitro. 2012 BMC Res Notes pmid:22336099
Aling J and Podczeck F The filling of powdered herbs into two-piece hard capsules using hydrogenated cotton seed oil as lubricant. 2012 Eur J Pharm Sci pmid:22960627
Qu J et al. Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. 2012 Biotechnol Biofuels pmid:22377043
Kottala N et al. Evaluation of the performance characteristics of bilayer tablets: Part II. Impact of environmental conditions on the strength of bilayer tablets. 2012 AAPS PharmSciTech pmid:22965660
Som I et al. Status of surfactants as penetration enhancers in transdermal drug delivery. 2012 J Pharm Bioallied Sci pmid:22368393
Al-Ghamdi AF et al. Development of square-wave adsorptive stripping voltammetric method for determination of acebutolol in pharmaceutical formulations and biological fluids. 2012 Chem Cent J pmid:22353684
Wolańska D and Kłosiewicz-Latoszek L [Fatty acids intake and serum lipids profile in overweighted and obese adults]. 2012 Rocz Panstw Zakl Hig pmid:22928362
Walash MI et al. Simultaneous determination of sulpiride and mebeverine by HPLC method using fluorescence detection: application to real human plasma. 2012 Chem Cent J pmid:22333299
Craig OE et al. Distinguishing wild ruminant lipids by gas chromatography/combustion/isotope ratio mass spectrometry. 2012 Rapid Commun. Mass Spectrom. pmid:22956328
Darwish IA et al. Novel spectrophotometric method for determination of cinacalcet hydrochloride in its tablets via derivatization with 1,2-naphthoquinone-4-sulphonate. 2012 Chem Cent J pmid:22305461
Ghanam RH et al. Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. 2012 Front Microbiol pmid:22363329
Rozema E et al. Selected Extracts of Chinese Herbal Medicines: Their Effect on NF-κB, PPARα and PPARγ and the Respective Bioactive Compounds. 2012 Evid Based Complement Alternat Med pmid:22675394
Sharma A and Chauhan RS In silico identification and comparative genomics of candidate genes involved in biosynthesis and accumulation of seed oil in plants. 2012 Comp. Funct. Genomics pmid:22312320
Patel K et al. Duloxetine HCl lipid nanoparticles: preparation, characterization, and dosage form design. 2012 AAPS PharmSciTech pmid:22167415
Busignies V et al. Prediction of the compressibility of complex mixtures of pharmaceutical powders. 2012 Int J Pharm pmid:22759643
Jubie S et al. Synthesis, antidepressant and antimicrobial activities of some novel stearic acid analogues. 2012 Eur J Med Chem pmid:22770606
Zhang J et al. Synthesis of NaYF(4):Yb/Er/Gd up-conversion luminescent nanoparticles and luminescence resonance energy transfer-based protein detection. 2012 Anal. Biochem. pmid:22155069
Krogager TP et al. Identification of a potential biomarker panel for the intake of the common dietary trans fat elaidic acid (trans∆9-C18:1). 2012 J Proteomics pmid:22483997
Pawar AA et al. Influence of precursor solvent properties on matrix crystallinity and drug release rates from nanoparticle aerosol lipid matrices. 2012 Int J Pharm pmid:22469694
Zhu S et al. Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity. 2012 Bioconjug. Chem. pmid:22471294
Wajid NA and Halpern BP Oral cavity discrimination of vapor-phase long-chain 18-carbon fatty acids. 2012 Chem. Senses pmid:22459162
Gröblacher B et al. Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. 2012 Bioorg. Med. Chem. pmid:22459211
Nakagawa H et al. Evaluation of infrared-reflection absorption spectroscopy measurement and locally weighted partial least-squares for rapid analysis of residual drug substances in cleaning processes. 2012 Anal. Chem. pmid:22449097
Ménard N et al. Novel surfactants with diglutamic acid polar head group: drug solubilization and toxicity studies. 2012 Pharm. Res. pmid:22451248
Sellami M et al. Enzymatic transesterification of palm stearin and olein blends to produce zero-trans margarine fat. 2012 BMC Biotechnol. pmid:22889174
Li Y et al. New bactericidal surgical suture coating. 2012 Langmuir pmid:22877364
Das SC and Stewart PJ Characterising surface energy of pharmaceutical powders by inverse gas chromatography at finite dilution. 2012 J. Pharm. Pharmacol. pmid:22881445
Wang YN et al. [Study on chemical constituents from Anoectochilus chapaensis]. 2012 Zhong Yao Cai pmid:23236826
Hu SY et al. [Studies on sustained release solid dispersion of tripterine carried by HPMC-stearic acid]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23311152
Yavuz B et al. An overview on dry eye treatment: approaches for cyclosporin a delivery. 2012 ScientificWorldJournal pmid:22619624
de Jong S et al. A semipermanent coating for preventing protein adsorption at physiological pH in kinetic capillary electrophoresis. 2012 Electrophoresis pmid:22899267
Dziewulska A et al. Monounsaturated fatty acids are required for membrane translocation of protein kinase C-theta induced by lipid overload in skeletal muscle. 2012 Mol. Membr. Biol. pmid:22881371
Zhang WY et al. Chronic unpredictable mild stress affects myocardial metabolic profiling of SD rats. 2012 J Pharm Biomed Anal pmid:22658902
Tuli RA et al. Studies on the effect of the size of polycaprolactone microspheres for the dispersion of salbutamol sulfate from dry powder inhaler formulations. 2012 Pharm. Res. pmid:22584947
Itoh Y and Hasegawa T Polarization dependence of Raman scattering from a thin film involving optical anisotropy theorized for molecular orientation analysis. 2012 J Phys Chem A pmid:22551093
Gellrich V et al. Behavior of perfluorinated compounds in soils during leaching experiments. 2012 Chemosphere pmid:22391048
Muro M et al. Molecular rearrangement in a zinc stearate Langmuir film dependent on a film preparation method studied using polarization-modulation infrared reflection absorption spectroscopy and X-ray absorption fine structure. 2012 J Phys Chem B pmid:22339471
Okoye P et al. To evaluate the effect of various magnesium stearate polymorphs using powder rheology and thermal analysis. 2012 Drug Dev Ind Pharm pmid:22304483
Simonsen ME et al. Comparison of methods for evaluation of activity of photocatalytic films. 2012 Environ Sci Pollut Res Int pmid:23054739
Dobrzyn P et al. Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation. 2012 Mitochondrion pmid:21664496
Dawes J et al. An investigation into the impact of magnesium stearate on powder feeding during roller compaction. 2012 Drug Dev Ind Pharm pmid:21810064
Guo C et al. In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. 2012 J Nanosci Nanotechnol pmid:22523972
Bevilacqua A et al. Selection of Yeasts as Starter Cultures for Table Olives: A Step-by-Step Procedure. 2012 Front Microbiol pmid:22666220
Shah KU and Khan GM Regulating drug release behavior and kinetics from matrix tablets based on fine particle-sized ethyl cellulose ether derivatives: an in vitro and in vivo evaluation. 2012 ScientificWorldJournal pmid:22649325
Polizzotti BD et al. Intrapericardial delivery of gelfoam enables the targeted delivery of Periostin peptide after myocardial infarction by inducing fibrin clot formation. 2012 PLoS ONE pmid:22590609
Song IS et al. Pharmacogenetics meets metabolomics: discovery of tryptophan as a new endogenous OCT2 substrate related to metformin disposition. 2012 PLoS ONE pmid:22590580
Ahmed TA et al. Miconazole nitrate oral disintegrating tablets: in vivo performance and stability study. 2012 AAPS PharmSciTech pmid:22585373
Varshosaz J et al. Development and evaluation of a novel pellet-based tablet system for potential colon delivery of budesonide. 2012 J Drug Deliv pmid:22577558