stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of stearic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with stearic acid?

stearic acid is suspected in Obesity, Diabetes, Fatty Liver, Hyperinsulinism, Cardiovascular Diseases, Infection and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with stearic acid

PubChem Associated disorders and diseases

What pathways are associated with stearic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with stearic acid?

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What functions are associated with stearic acid?


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What lipids are associated with stearic acid?

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What genes are associated with stearic acid?

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What common seen animal models are associated with stearic acid?

Knock-out

Knock-out are used in the study 'Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis.' (Anderson EK et al., 2012) and Knock-out are used in the study 'Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.' (Wu JH et al., 2013).

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Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with stearic acid

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Authors Title Published Journal PubMed Link
Chen Y et al. A new method to obtain Fourier transform infrared spectra free from water vapor disturbance. 2010 Appl Spectrosc pmid:20925991
Mukherjee S et al. Stearic acid delivery to corneum from a mild and moisturizing cleanser. 2010 J Cosmet Dermatol pmid:20883293
Rideout TC et al. Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice. 2010 Mol Nutr Food Res pmid:20333723
Westerbacka J et al. Splanchnic balance of free fatty acids, endocannabinoids, and lipids in subjects with nonalcoholic fatty liver disease. 2010 Gastroenterology pmid:20600015
Almeida CP et al. Modification of composition of a nanoemulsion with different cholesteryl ester molecular species: effects on stability, peroxidation, and cell uptake. 2010 Int J Nanomedicine pmid:20957219
Ram HN et al. Formulation and evaluation of floating tablets of liquorice extract. 2010 Pharmacognosy Res pmid:21589757
Pedersen PJ et al. Liposomal formulation of retinoids designed for enzyme triggered release. 2010 J. Med. Chem. pmid:20405849
Jain S et al. Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. 2010 J Young Pharm pmid:21264091
Liew CV et al. In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. 2010 Int J Pharm pmid:19922776
Naumova EA et al. Influence of individual saliva secretion on fluoride bioavailability. 2010 Open Dent J pmid:21221176
Harvey KA et al. Long-chain saturated fatty acids induce pro-inflammatory responses and impact endothelial cell growth. 2010 Clin Nutr pmid:19926177
Patel BP et al. Formulation and evaluation of mouth dissolving tablets of cinnarizine. 2010 Indian J Pharm Sci pmid:21218071
Kotagale NR et al. Carbopol 934-Sodium Alginate-Gelatin Mucoadhesive Ondansetron Tablets for Buccal Delivery: Effect of pH Modifiers. 2010 Indian J Pharm Sci pmid:21218058
Zhou Q et al. Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating. 2010 J Pharm Sci pmid:19795479
Swami G et al. Soyabean powder as a novel diluent in tablet formulation of simvastatin. 2010 Indian J Pharm Sci pmid:21218051
Balch RJ and Trescot A Extended-release morphine sulfate in treatment of severe acute and chronic pain. 2010 J Pain Res pmid:21197323
Uchimoto T et al. Lubrication properties of potential alternative lubricants, glycerin fatty acid esters, to magnesium stearate. 2010 Int J Pharm pmid:19913080
Remya K et al. Formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets. 2010 J Young Pharm pmid:21042477
Contreras GA et al. Lipomobilization in periparturient dairy cows influences the composition of plasma nonesterified fatty acids and leukocyte phospholipid fatty acids. 2010 J. Dairy Sci. pmid:20494158
Sateesha S et al. Influence of Organic Acids on Diltiazem HCl Release Kinetics from Hydroxypropyl Methyl Cellulose Matrix Tablets. 2010 J Young Pharm pmid:21042476
Karande AD et al. In-line quantification of micronized drug and excipients in tablets by near infrared (NIR) spectroscopy: Real time monitoring of tabletting process. 2010 Int J Pharm pmid:20558264
Hurko O et al. Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. 2010 Int J Alzheimers Dis pmid:20981353
Kim IS and Oh IJ Preparation and characterization of stearic acid-pullulan nanoparticles. 2010 Arch. Pharm. Res. pmid:20512475
A J et al. Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses. 2010 PLoS ONE pmid:20949032
Wang J et al. Solid-state interactions of a drug substance and excipients and their impact on tablet dissolution: a thermal-mechanical facilitated process-induced transformation or PIT. 2010 J Pharm Sci pmid:20533436
Karande AD et al. Calibration sampling paradox in near infrared spectroscopy: a case study of multi-component powder blend. 2010 Int J Pharm pmid:20472048
Akihisa T et al. Triterpene alcohol and fatty acid composition of shea nuts from seven African countries. 2010 J Oleo Sci pmid:20513968
Brown AW et al. Plant sterol and stanol substrate specificity of pancreatic cholesterol esterase. 2010 J. Nutr. Biochem. pmid:19615880
Tripathi B and Platel K Finger millet (Eleucine coracana) flour as a vehicle for fortification with zinc. 2010 J Trace Elem Med Biol pmid:20122580
Huang WH et al. Development of liposomal salbutamol sulfate dry powder inhaler formulation. 2010 Biol. Pharm. Bull. pmid:20190418
Rivera CA et al. Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis. 2010 BMC Gastroenterol pmid:20509914
Barupal DK et al. Hydrocarbon phenotyping of algal species using pyrolysis-gas chromatography mass spectrometry. 2010 BMC Biotechnol. pmid:20492649
Ye M et al. Synthesis of Sb2E3 (E = S, Se) nanorods with a flat cross section by a rapid hot injection method. 2010 J Nanosci Nanotechnol pmid:21138031
Blanco M and Peguero A Influence of physical factors on the accuracy of calibration models for NIR spectroscopy. 2010 J Pharm Biomed Anal pmid:20044229
Lin SY et al. Solid-state transformation of different gabapentin polymorphs upon milling and co-milling. 2010 Int J Pharm pmid:20561572
Asai T and Fujimoto Y Cyclic fatty acyl glycosides in the glandular trichome exudate of Silene gallica. 2010 Phytochemistry pmid:20541780
Foster SP and Johnson CP Feeding and hemolymph trehalose concentration influence sex pheromone production in virgin Heliothis virescens moths. 2010 J. Insect Physiol. pmid:20540946
Thörn K and Bergsten P Fatty acid-induced oxidation and triglyceride formation is higher in insulin-producing MIN6 cells exposed to oleate compared to palmitate. 2010 J. Cell. Biochem. pmid:20524206
Zhou QT et al. Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders. 2010 Eur J Pharm Sci pmid:20433919
Nokhodchi A et al. Physico-mechanical and dissolution behaviours of ibuprofen crystals crystallized in the presence of various additives. 2010 Daru pmid:22615598
Croxton RS et al. Variation in amino acid and lipid composition of latent fingerprints. 2010 Forensic Sci. Int. pmid:20413233
Milanovic J et al. Microencapsulation of flavors in carnauba wax. 2010 Sensors (Basel) pmid:22315575
Shi X et al. On the coating of precipitated calcium carbonate with stearic acid in aqueous medium. 2010 Langmuir pmid:20334413
Nagaich U et al. Design and evaluation of a metronidazole central core matrix tablet. 2010 J Adv Pharm Technol Res pmid:22247836
Bhattacharya S and Nagaich U Assessment of anti-nociceptive efficacy of costus speciosus rhizome in swiss albino mice. 2010 J Adv Pharm Technol Res pmid:22247830
O'Byrne SM et al. Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice. 2010 Am. J. Physiol. Endocrinol. Metab. pmid:20040693
Collins JM et al. De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury. 2010 J. Biol. Chem. pmid:20032470
Kushner J and Moore F Scale-up model describing the impact of lubrication on tablet tensile strength. 2010 Int J Pharm pmid:20667504
Zhang Y et al. The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity. 2010 J. Lipid Res. pmid:19609006
Thomas CP et al. Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. 2010 J. Biol. Chem. pmid:20061396